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determination of matrine
相关语句
  苦参碱的含量
     Quantitative Determination of Matrine in Gandean Capsule(肝得安胶囊) by TLCS
     薄层扫描法测定肝得安胶囊中苦参碱的含量
短句来源
     Determination of matrine injection by HPLC
     HPLC法测定苦参碱注射液中苦参碱的含量
短句来源
     HPLC method is used for the determination of matrine in Compound radix euphorbiae fischerianae injection with the column of Shim pack CLC ODS, the mobile phase of acetonitrile 0.02 mol·L -1 sodium phosphate monobasic (60∶40), detection wavelength of 210 nm.
     采用 HPL C法 ,以 Shim-pack CL C-ODS为色谱柱 ,乙腈 -0 .0 2 mol· L- 1 磷酸二氢钠 (60∶ 40 )为流动相 ,检测波长 2 1 0 nm,测定复方狼毒注射液中苦参碱的含量
短句来源
     Determination of matrine contents in zhiyang tincture by RP-HPLC
     HPLC法测定止痒酊中苦参碱的含量
短句来源
     Determination of Matrine in Ganyanlin Injection by HPLC
     HPLC法测定肝炎灵注射液中苦参碱的含量
短句来源
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  苦参碱含量测定
     Methodological comparison of the determination of Matrine in Sophors flavescens Ait
     苦参药材中苦参碱含量测定方法比较研究
短句来源
     Study of Determination of Matrine in Xin'an Granules
     心安颗粒中苦参碱含量测定方法的研究
短句来源
     Objective To establish an HPLC method for determination of matrine in Fuan Xiaozhen Lotions.
     目的建立对妇安消疹洗液中苦参碱含量测定的方法。
短句来源
  测定苦参碱
     Determination of matrine injection by HPLC
     HPLC法测定苦参碱注射液中苦参碱的含量
短句来源
     Study on Determination of Matrine Injection by HPLC
     HPLC法测定苦参碱注射液含量的方法研究
短句来源
     HPCE Determination of Matrine in Matrine Liposome
     高效毛细管电泳法测定苦参碱脂质体中苦参碱的含量
短句来源
     OBJECTIVE:To establish a method for content determination of matrine in it's liposomes by acid dye colorime_ try.
     目的:建立以酸性染料比色法测定苦参碱脂质体中苦参碱含量的方法。
短句来源
     Determination of Matrine and Impurities in Matrine Glucose Injection by HPLC
     HPLC法测定苦参碱葡萄糖注射液中的苦参碱
短句来源
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  “determination of matrine”译为未确定词的双语例句
     Determination of matrine and phillyrin in Jieyinjing Suppositories by HPLC
     HPLC法测定洁阴净栓中苦参碱和连翘苷的含量
短句来源
     Determination of Matrine Sodium Chloride Injections Related Substances by HPLC
     苦参碱氯化钠注射液有关物质的HPLC测定
短句来源
     Recovery of determination of Matrine (n5) was 99.56 ? 0.59%Accuracy of determination of Matrine was 0.65% within day and 0.70%between day.
     本法回收率99.56±0.59%,日内RSD0.65%,日间RSD0.70%。
短句来源
     Determination of Matrine in Cream by Micella HPLC
     乳膏中苦参碱的胶束HPLC法测定
短句来源
     Objective To establish the method for the determination of matrine in Ganyanlin injection by high performance liquid chromatography (HPLC).
     目的 建立肝炎灵注射液中苦参碱含量的HPLC测定方法。
短句来源
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  determination of matrine
Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly impr
      


A method for the simultaneous determination of Matrine and Oxymatrine in the same biological materials and the metabolic fate of the latter compound are described.There is a wide variation between the distribution and excretion of Oxymatrine administered to rats by different routes. After im injection of Oxymatrine, the parent drug concentration was found to be high in the tissue, bile and urine. However, when Oxymatrine was given orally, Matrine concentration was higher than that of Oxymatrine in...

A method for the simultaneous determination of Matrine and Oxymatrine in the same biological materials and the metabolic fate of the latter compound are described.There is a wide variation between the distribution and excretion of Oxymatrine administered to rats by different routes. After im injection of Oxymatrine, the parent drug concentration was found to be high in the tissue, bile and urine. However, when Oxymatrine was given orally, Matrine concentration was higher than that of Oxymatrine in all tissues. This indicates that Oxymatrine may be converted to Matfine in the G-Ⅰ tract. After absorption, Matrine was distributed to the tissues and excreted in the urine. After iv injection, Oxymatrine rapidly disappeared from plasma.These results showed that Matrine is probably the pharmacologically active substance in the treatment of asthma.Institute of Materia Medica, Chinese Academy of Medical Sciences, BeijingDepartment of Pharmacology, Quiyang Medical College

本文报告氧化苦参碱在动物体内的吸收、分布、排泄和转化的动态情况。静脉注射氧化苦参碱后,大鼠血浆中的药物浓度呈双相指数下降,符合开放式二室模型(T 1/2(a)=5.0min,T 1/2(β)=27.0 min)。氧化苦参碱经不同途径给药,药物在体内的转化有较大的差异。肌肉注射氧化苦参碱后,药物在大鼠组织中的分布以氧化苦参碱为主,尿中排出大量原形药,24小时内排出氧化苦参碱占排出总量的85.3%,说明肌肉注射后药物在体内转化较少。口服后,氧化苦参碱在大鼠或小鼠胃肠道中逐渐转化成苦参碱被吸收,药物在大鼠组织中的分布,苦参碱的含量比氧化苦参碱高,尿排泄也以苦参碱为主,24小时内占排出总量的80.1%,人口服氧化苦参碱后,屎排泄苦参碱比氧化苦参碱高。实验证明,苦参碱可能是平喘作用的有效形式。

The article describes the quantitative determination of matrine and oxymat oxymatrinein Shandougen (Radix Sophorae Tonkinensis) with a TLC-Densitometry. The method is simple,sensitive and accurate.It was applied to the determination of matrine and oxymatrine in Shandougen from different habitates. The results showed that the alkaloid content in Shandougen fromNanning, Guangxi province was higher than that in other habitates.

采用薄层光密度法测定山豆根中苦参碱及氧化苦参碱的含量,双波长反射法锯齿形扫描,波长s=502nm,R=650um,苦参碱及氧化苦参碱的平均回收率为101.4%及101.7%,r为2.1%及2.3%。用本法测定了八批不同来源的药材含量并进行了比较,为评价山豆根质量提供了数据,该方法灵敏度高,重现性、准确性好。

TLC scanning technique was, developed for the determination of matrine in Jieshenbao lotion. The method is simple, and highly sensitive, with an average recovery of 99.87%and a variation cofficient of 1.33%.

采用薄层扫描法测定法身宝洗剂中苦参碱的含量。平均回收率99.87%,变异系数1.33%

 
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