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release carrier
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  释载体
     Conclusion The rhBMP2 -dex-HM can promote the proliferation and differentiation of osteoblasts through a long period of controlled release of rhBMP-2.Hydrogel microspheres may be an ideal controlled release carrier for growth factors.
     结论 rhBMP 2 dex HM可以较长时间持续释放活性rhBMP 2 ,作为rhBMP 2的缓释载体 ,可以明显促进成骨细胞增殖和分化。
短句来源
     Experiment Study of Ultra-Fine Montmorillonite Used as a Control Release Carrier of Fluorouracil
     超细蒙脱石制备及其作为氟尿嘧啶药物控释载体的实验研究
短句来源
     [Method]Bone defects of 15 mm were created on the bilateral radius in rabbits and treated with four kinds of implantations,ie,composition of transgeneie MSCs and PLA/PCL(Group A),composition of MSCs and gradual release carrier for BMP-2(Group B),composition of MSCs and PLA/PCL(Group C),and PLA/PCL alone(Group D).
     [方法]于兔双侧桡骨中段造成1·5cm骨缺损,采用4种方法修复:A组植入转基因骨髓间质干细胞(MSCs)与PLA/PCL(聚乳酸/聚己内酯)支架的复合物; B组植入单纯MSCs与含重组BMP-2的PLA/PCL缓释载体的复合物;
短句来源
     Comparison between gene therapy and gradual release carrier for bone morphogenetic protein-2 in repairing bone defects
     骨形态发生蛋白2基因治疗与缓释载体修复骨缺损的比较研究
短句来源
     Conclusion:It can be concluded that CPC showed its characteristics as a sustained delivery system for rhBMP-2 and may be used as a novel sustained release carrier for rhBMP-2 in clinic.
     结论 :CPC能对rhBMP -2有缓慢而持久的体外缓释作用 ,有望充当rhBMP -2的缓释载体 ,但缓释速度尚有待提高
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  缓释载体
     Conclusion The rhBMP2 -dex-HM can promote the proliferation and differentiation of osteoblasts through a long period of controlled release of rhBMP-2.Hydrogel microspheres may be an ideal controlled release carrier for growth factors.
     结论 rhBMP 2 dex HM可以较长时间持续释放活性rhBMP 2 ,作为rhBMP 2的缓释载体 ,可以明显促进成骨细胞增殖和分化。
短句来源
     [Method]Bone defects of 15 mm were created on the bilateral radius in rabbits and treated with four kinds of implantations,ie,composition of transgeneie MSCs and PLA/PCL(Group A),composition of MSCs and gradual release carrier for BMP-2(Group B),composition of MSCs and PLA/PCL(Group C),and PLA/PCL alone(Group D).
     [方法]于兔双侧桡骨中段造成1·5cm骨缺损,采用4种方法修复:A组植入转基因骨髓间质干细胞(MSCs)与PLA/PCL(聚乳酸/聚己内酯)支架的复合物; B组植入单纯MSCs与含重组BMP-2的PLA/PCL缓释载体的复合物;
短句来源
     Comparison between gene therapy and gradual release carrier for bone morphogenetic protein-2 in repairing bone defects
     骨形态发生蛋白2基因治疗与缓释载体修复骨缺损的比较研究
短句来源
     Conclusion:It can be concluded that CPC showed its characteristics as a sustained delivery system for rhBMP-2 and may be used as a novel sustained release carrier for rhBMP-2 in clinic.
     结论 :CPC能对rhBMP -2有缓慢而持久的体外缓释作用 ,有望充当rhBMP -2的缓释载体 ,但缓释速度尚有待提高
短句来源
     Conclusion:Fibrin glue can be used as a good sustained release carrier of MTX or CDDP,except ADM.
     结论:纤维蛋白胶可作为CDDP、MTX而不是阿霉素(ADM)的良好缓释载体,并可增强前两者的药效。
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  “release carrier”译为未确定词的双语例句
     Study on the development of slow release carrier urea and its release mechanism
     载体尿素的研制及其释放机理研究初探
短句来源
     The release properties could be expressed by the following equation: Q = 2.1811 t + 13.50 ( r =0.9527). These materials have good prospect as a controlled or sustained release carrier.
     阐明了载体中加入D ,L PLA材料 ,改善了以PHBV单一材料为载体的微球释药性能 ,体外释药方程为Q =2 .1811t +13.5 0 (r =0 .95 2 7)
短句来源
     [Objective]To compare the effects between gene therapy and gradual release carrier for bone morphogenetic protein-2(BMP-2)in repairing bone defects.
     [目的]比较骨形态发生蛋白2(BMP-2)基因治疗与生长因子缓释方法修复节段性骨缺损效果。
短句来源
     Application of sustained release carrier containing antibiotic and anti-inflammatory drugs to firearm wounds of extremities after seawater immersion
     抗菌抗炎药物缓释体在海水浸泡肢体软组织火器伤救治中的应用
短句来源
     PRELIMINARY STUDY ON CONTROLLED/SLOW RELEASE CARRIER NITROGEN FERTILIZERS
     载体缓控释尿素研制初探
短句来源
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  release carrier
Protein incorporation within Ti scaffold for bone ingrowth using Sol-gel SiO2 as a slow release carrier
      
The average pore size of PVA sponges used in this study was 30, 60, 110, 250, 350, and 700 μm and gelatin microspheres were employed as release carrier of bFGF.
      
Characteristics of clay as a slow-release carrier of Zn by direct implantation into tree trunks
      
EO105PO27EO105 copolymer is expected to be useful as a novel sustained-release carrier that maintains constant release rates for the volatility of perfume compounds over a wide temperature range.
      
Poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) triblock copolymer as a sustained-release carrier for perfume co
      
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This article presents 149 cases of peridental diseases treated with carboxymethyl cellulose as peridental sustained release membrane for local application with good therapeutic effect. The results showed that this treatment had the advantages of smaller dose, high local concentration, satisfactory curative effect, no adverse reaetions, being not liable to produce drug-fast bacteria strains and ready reception from the patients. The paper also discusses the merits of taking the carboxymethylcellulose natrium...

This article presents 149 cases of peridental diseases treated with carboxymethyl cellulose as peridental sustained release membrane for local application with good therapeutic effect. The results showed that this treatment had the advantages of smaller dose, high local concentration, satisfactory curative effect, no adverse reaetions, being not liable to produce drug-fast bacteria strains and ready reception from the patients. The paper also discusses the merits of taking the carboxymethylcellulose natrium as peridental sustained release carrier: it can be dissolved in saliva, gingival sulcus fluid and blood; release slowly so that it may mantain a longer effective concentration in the local part, being beneficial to kill the bacteria.

以羧甲基纤维素钠作牙周缓释剂局部应用治疗牙周病149例。结果表明本药具有用药剂量小、局部浓度高、效果好、无副作用、不易形成耐药菌株、且病人易于接受等优点。还进一步讨论了以羧甲基纤维素钠作牙周缓释剂载体材料,能被唾液、龈沟液、血液等溶解而药物缓慢、持久释放,使局部维持有效药物浓度时间较长,有利于杀菌。

Objective: To determine whether chitosan can be used as a drug carrier in treatment of giant cell tumor of bone (GCT). Methods: In vitro chemosensitivities of chitosan and chitosan with adriamycin(ADM),cisplachitin (CDDP), and methotrexate(MTX) to GCT were tested by using MTT method. Results:The only chitosan was had no inhibitory effect on GCT (inhibitory rate:1.8%),the inhibitory rates of chitosan with ADM,CDDP and MTX were higher than that of chitosan with ADM,CDDP and MTX in equal concentration (maximum...

Objective: To determine whether chitosan can be used as a drug carrier in treatment of giant cell tumor of bone (GCT). Methods: In vitro chemosensitivities of chitosan and chitosan with adriamycin(ADM),cisplachitin (CDDP), and methotrexate(MTX) to GCT were tested by using MTT method. Results:The only chitosan was had no inhibitory effect on GCT (inhibitory rate:1.8%),the inhibitory rates of chitosan with ADM,CDDP and MTX were higher than that of chitosan with ADM,CDDP and MTX in equal concentration (maximum concentration in plasma),but there were no marked differences (P>0.05). Conclusion:Chitosan can be used as a good sustained release carrier of ADM,CDDP and MTX.As the chemotherapeutic concentration of GCT is high (the inhibitory rates of ADM,CDDP,MTX in maximum concentration in plasma were 17.06%,15.87%,7.09%),usual injection in vein or local giving is not suited,and so it may be useful for sensitivity chemical drugloaded chitosan drug delivery system used for local treatment of GCT to reduce the recurrent rate after operation.

目的:确定壳多糖(几丁糖)是否可作为骨巨细胞瘤治疗的药物载体。方法:用壳多糖及壳多糖联合阿霉素、顺氨氯铂及甲氨蝶呤对骨巨细胞瘤进行体外敏感实验(MTT法)。结果:单纯壳多糖对骨巨细胞瘤在体外无抑制作用(抑制率为1.8%),壳多糖联合阿霉素、顺氨氯铂及甲氨蝶呤分别较单独应用相同浓度(血浆峰值浓度)药物的抑制率要高,但无显著差异(P>0.05)。结论:壳多糖可以作为阿霉素、顺氨氯铂及甲氨蝶呤的良好缓释载体。由于骨巨细胞瘤要求化疗药物浓度较高(阿霉素、顺氨氯铂及甲氨蝶呤的血浆峰值浓度的抑制率分别为17.06%,15.87%,7.09%),不适合常规的静脉及局部给药。故壳多糖与敏感药物制成的缓释系统用于局部治疗可在降低术后复发率上起到较为积极的作用。

Objective:To prepare recombinant human morphogenetic protein 2 (rhBMP 2)/coral composite attificial bone and to determine its osteoinductivity.Methods:The composite artificial bone was prepared by combining coral with rhBMP-2,and was implanted into the muscle pouches of mice.Sixty six mices were divited into three groups:Group 1, the composite bone (coral:rhBMP 2(w/w)=20∶1)transplanted;Group 2, the composite bone (coral∶rhBMP 2(w/w)=40∶1);and Group 3 the coral alone.All the animals were killed at intervals...

Objective:To prepare recombinant human morphogenetic protein 2 (rhBMP 2)/coral composite attificial bone and to determine its osteoinductivity.Methods:The composite artificial bone was prepared by combining coral with rhBMP-2,and was implanted into the muscle pouches of mice.Sixty six mices were divited into three groups:Group 1, the composite bone (coral:rhBMP 2(w/w)=20∶1)transplanted;Group 2, the composite bone (coral∶rhBMP 2(w/w)=40∶1);and Group 3 the coral alone.All the animals were killed at intervals of 1,3,5 weeks after operation.The speciments were evaluated by light microscope and image analysis.Results:Cartilage growth in the pores or on the surface of the implants was observed one week after operation, woven bone three weeks and lamellar bone with bone marrow six weeks,partial coral absorption was observed,the amount of induced endochondral bone was time and rhBMP 2 dose dependent.Conclusion:The results indicate that the composite possesses a superior osteoinductivity and coral may act as one of the most suitable rhBMP 2 slow releasing carriers currently available.

目的:制备珊瑚(coral)与重组人骨形成蛋白-2(rhBMP-2)复合人工骨并测试其骨诱导活性。方法:将rhBMP-2与珊瑚复合后植入鼠肌袋内。66只小鼠随机分为3组:第1组为复合骨(1∶20w/w);第2组为复合骨(1∶40w/w);第3组为单独珊瑚。术后1、3、6周处死动物,光镜下观察,并用图象分析法作成骨定量测定,结果:术后1周,可见复合材料表面及孔洞内有软骨形成。3周出现编织骨。6周形成含骨髓的板层骨。珊瑚被部分吸收。诱导成骨的量有时间依赖性和rhBMP-2剂量依赖性。结论:rhBMP-2/coral复合人工骨具有良好的诱导成骨能力;珊瑚可能是目前能使用的rhBMP-2最合适的缓释载体。

 
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