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release carrier
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  释载体
    Comparison between gene therapy and gradual release carrier for bone morphogenetic protein-2 in repairing bone defects
    骨形态发生蛋白2基因治疗与缓释载体修复骨缺损的比较研究
短句来源
    Conclusion The rhBMP2 -dex-HM can promote the proliferation and differentiation of osteoblasts through a long period of controlled release of rhBMP-2.Hydrogel microspheres may be an ideal controlled release carrier for growth factors.
    结论 rhBMP 2 dex HM可以较长时间持续释放活性rhBMP 2 ,作为rhBMP 2的缓释载体 ,可以明显促进成骨细胞增殖和分化。
短句来源
    Conclusion:Chitosan can be used as a good sustained release carrier of ADM,CDDP and MTX.
    结论:壳多糖可以作为阿霉素、顺氨氯铂及甲氨蝶呤的良好缓释载体
短句来源
    Conclusion:It can be concluded that CPC showed its characteristics as a sustained delivery system for rhBMP-2 and may be used as a novel sustained release carrier for rhBMP-2 in clinic.
    结论 :CPC能对rhBMP -2有缓慢而持久的体外缓释作用 ,有望充当rhBMP -2的缓释载体 ,但缓释速度尚有待提高
短句来源
    as a slow release carrier, HAG enhances the effectiveness of bFGF. The combination of bFGF, HAG and freeze dried bone allograft can repair the segmental bone defect more effectively.
    HAG作为缓释载体提高 b FGF的效能 ,它们复合异体冻干骨后能有效提高骨缺损的修复能力。
短句来源
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  缓释载体
    Comparison between gene therapy and gradual release carrier for bone morphogenetic protein-2 in repairing bone defects
    骨形态发生蛋白2基因治疗与缓释载体修复骨缺损的比较研究
短句来源
    Conclusion The rhBMP2 -dex-HM can promote the proliferation and differentiation of osteoblasts through a long period of controlled release of rhBMP-2.Hydrogel microspheres may be an ideal controlled release carrier for growth factors.
    结论 rhBMP 2 dex HM可以较长时间持续释放活性rhBMP 2 ,作为rhBMP 2的缓释载体 ,可以明显促进成骨细胞增殖和分化。
短句来源
    Conclusion:Chitosan can be used as a good sustained release carrier of ADM,CDDP and MTX.
    结论:壳多糖可以作为阿霉素、顺氨氯铂及甲氨蝶呤的良好缓释载体
短句来源
    Conclusion:It can be concluded that CPC showed its characteristics as a sustained delivery system for rhBMP-2 and may be used as a novel sustained release carrier for rhBMP-2 in clinic.
    结论 :CPC能对rhBMP -2有缓慢而持久的体外缓释作用 ,有望充当rhBMP -2的缓释载体 ,但缓释速度尚有待提高
短句来源
    as a slow release carrier, HAG enhances the effectiveness of bFGF. The combination of bFGF, HAG and freeze dried bone allograft can repair the segmental bone defect more effectively.
    HAG作为缓释载体提高 b FGF的效能 ,它们复合异体冻干骨后能有效提高骨缺损的修复能力。
短句来源
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  “release carrier”译为未确定词的双语例句
    [Objective]To compare the effects between gene therapy and gradual release carrier for bone morphogenetic protein-2(BMP-2)in repairing bone defects.
    [目的]比较骨形态发生蛋白2(BMP-2)基因治疗与生长因子缓释方法修复节段性骨缺损效果。
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  release carrier
Protein incorporation within Ti scaffold for bone ingrowth using Sol-gel SiO2 as a slow release carrier
      
The average pore size of PVA sponges used in this study was 30, 60, 110, 250, 350, and 700 μm and gelatin microspheres were employed as release carrier of bFGF.
      
Characteristics of clay as a slow-release carrier of Zn by direct implantation into tree trunks
      
EO105PO27EO105 copolymer is expected to be useful as a novel sustained-release carrier that maintains constant release rates for the volatility of perfume compounds over a wide temperature range.
      
Poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) triblock copolymer as a sustained-release carrier for perfume co
      
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Objective: To determine whether chitosan can be used as a drug carrier in treatment of giant cell tumor of bone (GCT). Methods: In vitro chemosensitivities of chitosan and chitosan with adriamycin(ADM),cisplachitin (CDDP), and methotrexate(MTX) to GCT were tested by using MTT method. Results:The only chitosan was had no inhibitory effect on GCT (inhibitory rate:1.8%),the inhibitory rates of chitosan with ADM,CDDP and MTX were higher than that of chitosan with ADM,CDDP and MTX in equal concentration (maximum...

Objective: To determine whether chitosan can be used as a drug carrier in treatment of giant cell tumor of bone (GCT). Methods: In vitro chemosensitivities of chitosan and chitosan with adriamycin(ADM),cisplachitin (CDDP), and methotrexate(MTX) to GCT were tested by using MTT method. Results:The only chitosan was had no inhibitory effect on GCT (inhibitory rate:1.8%),the inhibitory rates of chitosan with ADM,CDDP and MTX were higher than that of chitosan with ADM,CDDP and MTX in equal concentration (maximum concentration in plasma),but there were no marked differences (P>0.05). Conclusion:Chitosan can be used as a good sustained release carrier of ADM,CDDP and MTX.As the chemotherapeutic concentration of GCT is high (the inhibitory rates of ADM,CDDP,MTX in maximum concentration in plasma were 17.06%,15.87%,7.09%),usual injection in vein or local giving is not suited,and so it may be useful for sensitivity chemical drugloaded chitosan drug delivery system used for local treatment of GCT to reduce the recurrent rate after operation.

目的:确定壳多糖(几丁糖)是否可作为骨巨细胞瘤治疗的药物载体。方法:用壳多糖及壳多糖联合阿霉素、顺氨氯铂及甲氨蝶呤对骨巨细胞瘤进行体外敏感实验(MTT法)。结果:单纯壳多糖对骨巨细胞瘤在体外无抑制作用(抑制率为1.8%),壳多糖联合阿霉素、顺氨氯铂及甲氨蝶呤分别较单独应用相同浓度(血浆峰值浓度)药物的抑制率要高,但无显著差异(P>0.05)。结论:壳多糖可以作为阿霉素、顺氨氯铂及甲氨蝶呤的良好缓释载体。由于骨巨细胞瘤要求化疗药物浓度较高(阿霉素、顺氨氯铂及甲氨蝶呤的血浆峰值浓度的抑制率分别为17.06%,15.87%,7.09%),不适合常规的静脉及局部给药。故壳多糖与敏感药物制成的缓释系统用于局部治疗可在降低术后复发率上起到较为积极的作用。

Giant cell tumor of bone (GCT)is a semi—malignant tumor.There are high recurrentrates in this tumor after operation.7 specimens of GCT proved by pathology were cultured,then the chemosensisitivity of the primary cultures were tested by using MTT method,The results showed there were middle degree sensitivity to GCT in usual dose (1/250 of one clinical dose )of cisplachitin (CDDP)and adriamycin (ADM),The results of chemosensitivity test of echelon dense of chemical drug showed the lowest effective dense of ADM,CDDP...

Giant cell tumor of bone (GCT)is a semi—malignant tumor.There are high recurrentrates in this tumor after operation.7 specimens of GCT proved by pathology were cultured,then the chemosensisitivity of the primary cultures were tested by using MTT method,The results showed there were middle degree sensitivity to GCT in usual dose (1/250 of one clinical dose )of cisplachitin (CDDP)and adriamycin (ADM),The results of chemosensitivity test of echelon dense of chemical drug showed the lowest effective dense of ADM,CDDP and MTX were 0.4ug/ml, 2ug/ml, 3ug/ml, It is concluded GCT may be treated by ADM and CDDP to reduce the recurrent rate of GCT after operation. As the effeective dense of the drug is high,usual injection in vein and local giving are not suited,and the local treatment by drug delivery system made out by good sustained release carrier and sensitivity chemical drug may be the only effective mothed.

骨巨细胞瘤是一种半恶性的肿瘤,术后复发率较高。作者取经病理证实的骨巨细胞瘤标本(共7例)进行体外培养,并用MTT法进行原代细胞的化疗药物敏感试验及梯度浓度的化疗药物的敏感试验,结果显示,在常规剂量下(临床一次用量的1/250)骨巨细胞瘤对阿霉素及顺氨氯铂中度敏感,梯度试验表明,阿霉素、顺氨氯铂及甲氨蝶吟的最低有效抑制浓度分别为0.4ug/ml、2ug/ml和3us/ml,因此,骨巨细胞瘤可以应用阿霉素、顺氨氯铂等进行治疗以降低术后复发率,但由于有效浓度较高,不适合常规的静脉及局部给药,而仅适用于良好缓释载体与敏感化疗药物制成的缓释制剂的局部应用。

Objective To investigate the effect of fibrin glue (FG) as slowly-released carrier of bone morphogenetic protein (BMP). Methods The composite (BMP/FG) containing 200mg bovine BMP, 1.0g fibrinogen,100U thrombosin and 20ml mixed solvent was utilized in 16 cases of compression plating of fracture of femoral shaft, and was studied after operation by histological and ultrastructural observation, x-ray surveillance and safety supervision of 4 kinds of virus.Results The structure of BMP/FG was dense...

Objective To investigate the effect of fibrin glue (FG) as slowly-released carrier of bone morphogenetic protein (BMP). Methods The composite (BMP/FG) containing 200mg bovine BMP, 1.0g fibrinogen,100U thrombosin and 20ml mixed solvent was utilized in 16 cases of compression plating of fracture of femoral shaft, and was studied after operation by histological and ultrastructural observation, x-ray surveillance and safety supervision of 4 kinds of virus.Results The structure of BMP/FG was dense and compact, callus appeared one month after the implantation, the effect of biological plating formed at 3rd month, and no virus infection was found.Conclusions FG which is the ideal slowly-released carrier for BMP.BMP/FG can lead to the effect of biological plating and its virus infection can be monitored.

目的 用纤维蛋白黏合剂(fibrin glue,FG)作为骨形态发生蛋白(BMP) 的缓释放载体,以增强诱导成骨效果。方法 粗制bBMP200 mg,纤维蛋白原1 .0 g,凝血酶100 U,混合溶解液20ml 组成复合物(bBMP/FG) ;临床应用于股骨干骨折加压钢板内固定16 例,并进行bBMP/FG的超微结构、X线片观察及4 种病毒的安全监控。结果 bBMP/FG结构致密厚实;术后1 个月出现新骨,3个月形成“生物接骨板”效应;16 例均未发现病毒感染。结论 FG 是BMP 理想的缓释放载体,BMP/FG可形成“生物接骨板”效应,而且其病毒感染可以监控

 
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