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      抗肿瘤免疫反应     
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  anti tumor immune response
     The Experimental Study on Idiotypic DNA Vaccine against Human B-cell Lymphoma to Induce Antitumor Immune Response
     人B细胞淋巴瘤独特型DNA疫苗诱导抗肿瘤免疫反应的实验研究
短句来源
     Conclusion Immunotherapy with IL 2 and IFN α synergies with cryotherapy possibly enhance a systemic, specific anti tumor immune response.
     结论 用 IFN -α和 r IL - 2免疫治疗协同冷冻治疗可能通过诱发全身性、特异性抗肿瘤免疫反应 ,获得更好的疗效。
短句来源
     Induction of potent antitumor immune response of leukemia antigen pulsed dendritic cells by IL 2 gene modification
     IL-2基因修饰增强白血病抗原冲击的树突状细胞诱导的抗肿瘤免疫反应
短句来源
     Objective To observe whether antitumor immune response can be induced in BALB/c mice immunized with a fusion protein (6Bl1mGM) of anti-idiotypic single chain antibody (6B11scFv) and murine granulocyte-macrophage colony-stimulating factor (GM-CSF) instead of ovarian carcinoma antigen.
     目的 观察卵巢癌抗独特型单链抗体 6B11ScFv与鼠粒细胞巨噬细胞集落刺激因于(murine granulocvte-macrophage colony-stimulating factor.mGM-CSF)的融合蛋白(6B11mGM)在小鼠体内诱导抗肿瘤免疫反应情况,探讨此种融合蛋白作为卵巢癌疫苗的可能性及适当的免疫方法。
短句来源
     Conclusion: ATV NDV was a safe, effective and high specially immune pharmaceutics。 It can improve the patient anti tumor immune response
     结论 :经 NDV修饰的 ATV- NDV是一种免疫源性高和安全有效的免疫制剂 ,具有针对性强、特异性高的优点 ,并能改善患者的抗肿瘤免疫反应
短句来源
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  antitumor immune response
     The Experimental Study on Idiotypic DNA Vaccine against Human B-cell Lymphoma to Induce Antitumor Immune Response
     人B细胞淋巴瘤独特型DNA疫苗诱导抗肿瘤免疫反应的实验研究
短句来源
     Conclusion Immunotherapy with IL 2 and IFN α synergies with cryotherapy possibly enhance a systemic, specific anti tumor immune response.
     结论 用 IFN -α和 r IL - 2免疫治疗协同冷冻治疗可能通过诱发全身性、特异性抗肿瘤免疫反应 ,获得更好的疗效。
短句来源
     Induction of potent antitumor immune response of leukemia antigen pulsed dendritic cells by IL 2 gene modification
     IL-2基因修饰增强白血病抗原冲击的树突状细胞诱导的抗肿瘤免疫反应
短句来源
     Objective To observe whether antitumor immune response can be induced in BALB/c mice immunized with a fusion protein (6Bl1mGM) of anti-idiotypic single chain antibody (6B11scFv) and murine granulocyte-macrophage colony-stimulating factor (GM-CSF) instead of ovarian carcinoma antigen.
     目的 观察卵巢癌抗独特型单链抗体 6B11ScFv与鼠粒细胞巨噬细胞集落刺激因于(murine granulocvte-macrophage colony-stimulating factor.mGM-CSF)的融合蛋白(6B11mGM)在小鼠体内诱导抗肿瘤免疫反应情况,探讨此种融合蛋白作为卵巢癌疫苗的可能性及适当的免疫方法。
短句来源
     Conclusion: ATV NDV was a safe, effective and high specially immune pharmaceutics。 It can improve the patient anti tumor immune response
     结论 :经 NDV修饰的 ATV- NDV是一种免疫源性高和安全有效的免疫制剂 ,具有针对性强、特异性高的优点 ,并能改善患者的抗肿瘤免疫反应
短句来源
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  anti-tumor immunity
     Non-replicating recombinant vaccinia virus expressing HPV16 E6 and E7 proteins elicits anti-tumor immunity in mice
     表达HPV16 E6和E7蛋白的非复制型重组痘苗病毒诱发的抗肿瘤免疫反应
短句来源
     Induction of specific anti-tumor immunity by interferon-γ gene transferred G422 mouse glioblastoma
     IFN-γ基因转染G422胶质母细胞瘤诱导的抗肿瘤免疫反应
短句来源
     Anti-tumor immunity in mice induced by synthetic polypeptides of MUC5AC and MUC6 apomucins
     MUC5AC、MUC6核粘蛋白合成肽诱导小鼠抗肿瘤免疫反应
短句来源
     Objective To explore mechanisms of the augmented anti-tumor immunity observed in reconstituted lymphopenic mice (RLM) receiving melanoma vaccination.
     目的阐明向免疫重建的淋巴细胞减少小鼠(reconstituted lymphopenic mice,RLM)进行瘤苗免疫增强抗肿瘤免疫反应的机制。
短句来源
     Conclusions Immature DC administrated intratumorally which were induced in vitro,could capture antigen of apoptosic tumor cells by low dose chemotherapy,enhance specific anti-tumor immunity.
     并能特异性杀伤小鼠前胃癌细胞MFC(P<0.01)。 结论体外诱导分化的未成熟DC,能于体内捕获小剂量化疗诱导的凋亡肿瘤细胞所携带的肿瘤抗原,诱导机体特异性抗肿瘤免疫反应
短句来源
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  anti-tumor immune response
     (2)H22-DC-TIL can induce to enhance specific anti-tumor Immune response of mice bearing tumor.
     (2)H22-DC-TIL可明显诱导提高荷瘤小鼠特异性抗肿瘤免疫反应
短句来源
     Conclusion Combined IL-12 and GM-CSF gene therapy can enhance the anti-tumor immune response of B16 melanoma bearing mice and decrease side-effect of using AdCMVIL-12.
     结论:IL-12与GM-CSF联合基因治疗可增强荷B16黑色素瘤小鼠的抗肿瘤免疫反应,并能有效降低单独应用AdCMVIL-12的毒副作用。
短句来源
     Background &Objective:Chemokines paly an important role in the infiltration of immune cells to t umor tissues. Anti-tumor immune response had been elicited in many tumor models by the chemokine gene transfectio n. The aim of this study was to evaluate the possibility of inducing anti-colorecta l cancer active immune response by tr ansfection of mouse colorectal cancer CMT93cells with c hemokine MCP-3gene.
     背景与目的:趋化因子对于免疫细胞在肿瘤组织中的浸润起重要作用,转染趋化因子基因在许多类型的肿瘤中诱导了抗肿瘤免疫反应,本研究的目的是通过将趋化因子单核细胞趋化蛋白-3(monocytechemotacticprotein-3,MCP-3)基因转染小鼠大肠癌CMT93瘤细胞,探讨MCP-3用于诱导抗大肠癌主动免疫的可行性。
短句来源
     Conclusion AdCMVGM-CSF can enhance the anti-tumor immune response of B16 melanoma bearing mice and inhibit the growth of tumor.
     结论:AdCMVGMCSF可增强荷B16黑色素瘤小鼠的抗肿瘤免疫反应,具有抑制肿瘤生长的作用。
短句来源
     Conclusion: Langerhans cells in the skin lesions could migrate and induce an anti-tumor immune response in MF.
     结论:MF皮损中朗格汉斯细胞发生迁移,参与了抗肿瘤免疫反应
短句来源

 

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      anti tumor immune response
    DCs that induce a Th1type response have been reported to be a key factor for the efficient induction of the anti-tumor immune response.
    例句来源      
    Effect of GMCSF and IL-2 co-expression on the anti-tumor immune response.
    例句来源      
    However GM-CSF also mediates crucial functions in host response to external stimuli, in inflammation and in the anti tumor immune response.
    例句来源      
    IFNhas also been reported to induce a potent anti-tumor immune response, largely because of the induction of MHC class I antigens.
    例句来源      
    It implies that cytokine gene transfer is capable of triggering anti-tumor immune response in bladder and eradicating existing/residual tumor.
    例句来源      
    更多          
      antitumor immune response
    Expression of immunostimulatory molecules on tumor cells by gene transfer can be used to induce an antitumor immune response.
    例句来源      
    Expression of interleukin-12 (IL-12) on tumor-cell membranes in a GPI-anchored form induces a strong antitumor immune response that is comparable to the effects of secretory IL-12.
    例句来源      
    Although there is ample evidence for the presence of tumor-associated antigens on a variety of tumors, they are seemingly unable to elicit an adequate antitumor immune response.
    例句来源      
    Surface anchorage of superantigen SEA promotes induction of specific antitumor immune response by tumor-derived exosomes
    例句来源      
    Crude and electrofocused antigen preparations capable of eliciting a protective antitumor immune response were used to prepare liposome vaccines.
    例句来源      
    更多          
      anti-tumor immunity
    Detection of anti-tumor immunity induced by laser immunotherapy
    例句来源      
    Molecular identification of tumor-associated antigens not only provided the means to activate or monitor anti-tumor immunity, but also gave insights into new and unexpected biochemical processes that are taking place within cells.
    例句来源      
    Dendritic cells (DC)-derived or tumor-derived exosomes are a population of nanometer sized membrane vesicles that can induce specific anti-tumor immunity.
    例句来源      
    Our findings suggest that Exo/IL-18 has more potent capability to induce specific anti-tumor immunity, and our strategy of IL-18 modification of exosomes is a feasible approach to develop exosomes-based tumor vaccines.
    例句来源      
    This apparent stimulation of anti-tumor immunity was observed in treated animals regardless of substrain or site of MER injection, and could not be correlated with the outcome of immunotherapy.
    例句来源      
    更多          
      anti-tumor immune response
    In vitro anti-tumor immune response induced by dendritic cells transfected with recombinant adenovirus carrying mutant k-ras gen
    例句来源      
    The specific anti-tumor immune response induced by mouse bone marrow dendritic cells (DCs) transfected with recombinant adenovirus carrying mutant k-ras genes was investigated.
    例句来源      
    Nitric oxide synthase inhibitor and IL-18 enhance the anti-tumor immune response of rats carrying an intrahepatic colon carcinom
    例句来源      
    Together, these results show that linkage of CD40L to a self-tumor antigen enhances the anti-tumor immune response in DC-based treatment.
    例句来源      
    The migration of leukocytes is, among other things, of primary importance for an anti-tumor immune response, whereas the migration of tumor cells is a prerequisite for invasion and the development of metastases.
    例句来源      
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             The ability to transfer anti-tumor immunity by spleen RNA of tumor bearing donors was evaluated both in in vitro and in vivo experiments in animals and human patients. In in vitro test of mixed lymphocyte-tumor cells reaction, it was found that normal lymphocytes behaved like the tumor-sensitized lymphocytes after the preincubation with spleen RNA of mice bearing Sarcoma180 in blastogenic response to these tumor cells, and thus the mediation of anti-tumor immunological responsiveness by spleen RNA of tumor ...
                本文对带瘤小鼠及肿瘤患者的脾RNA的传递免疫反应的能力进行了实验研究。用淋巴细胞——肿瘤细胞混合培养法对带S_(180)小鼠的脾RNA进行的体外培养实验表明,正常小鼠的淋巴细胞与带S_(180)小鼠的脾RNA温育后可以转变成为对S_(180)瘤细胞致敏的淋巴细胞。表现为在混合淋巴细胞——瘤细胞培养中的淋转率的提高。这就说明带瘤鼠的脾RNA可以有正常淋巴细胞传递抗S_(180)免疫反应的功能。在小鼠的活体抑瘤实验中,带S_(180)小鼠的脾RNA可对接种S_(180)小鼠的肿瘤生长有33.0—66.9%的抑瘤率,用正常脾RNA则没有效果;同样,用从胃癌患者切除的脾脏中提取的RNA对胃癌患者进行免疫治疗时,治疗组的四年存活率可达47.1%,对照组则为22.7%,治疗组的几项免疫指标均较治疗前有所提高。上述各项体外及活体实验的结果都说明带瘤供体的脾RNA可以传递特异的抗肿瘤免疫反应的信息,其效应和前人所报告的从免疫动物脾中提取的免疫RNA是完全一致的。
    文摘来源
             The antigen-specific binding cell (ABC) in EAC-bearing mice were detected by means of specific rosette-forming test after SRBC immunization. It was found that the number of ABC in host decreased gradually with EAC development. The ABC response of normal donors enhanced when thymocytes from the 5th day EAC-bearing mice were transferred into syngeneic mice, but declined while thymocytes transferred from the 10th day host. Contrastly, marrow cells or host spleen cells could not reconstitute the response of let...
                本文采用免疫特异性玫瑰花环形成试验检测了Ehrlich腹水癌(EAC)带瘤鼠体内特异性抗原结合细胞(ABC)的动态变化。发现随着EAC的进行性生长,ABC数量逐渐下降。但将第5天瘤鼠的胸腺细胞转移给正常受鼠可增强ABC反应,而第10天瘤鼠的胸腺细胞转移可明显降低ABC反应,且第10天瘤鼠的胸腺细胞加正常骨髓细胞转移或瘤鼠脾细胞单独转移对致死量γ射线照射鼠的免疫重建能力明显低于正常对照组,这提示ABC数量或功能的变化是宿主抗肿瘤免疫反应改变的重要原因之一。
    文摘来源
             The reactivity of a monoclonal anti-human leucocyte antibody, designated 1C34-5, with. various human normal and malignant tissues were tested by means of ELLSA as well as immunohistochemical staining. It was found that this antibody reacted only with normal leucocytes and malignant heamopoietic tissues so far tested. Pathological samples from 1 case of hairy cell leukemia, 10 cases of malignant lymphoma and 2 cases of Hodgkin's disease showed positive staining. In contrast, all 31 ofses of non-heamop-oietic...
                用免疫组化方法及EUSA测检研究抗人白细胞单克隆抗体1C34-5与正常及肿瘤细胞组织的反应性,发现1C34-5仅与正常的白细胞和淋巴造血组织来源的肿瘤细胞反应。在所观察的1例毛细胞白血病、10例恶性淋巴病,2例何杰金氏病的肿瘤组织均与1C34-5呈不同程度的阳性反应,而31例各种不同类型非淋巴造血组织来源的肿瘤均为阴性反应。浸润到肿瘤细胞间或邻近部位的淋巴样细胞也为阳性反应。此抗体在辅助鉴别形态学难以区分的小圆细胞癌和淋巴瘤的病理诊断中,将有一定意义。此外也为观察判断转移癌细胞分布及浸润程度,以及宿主抗肿瘤免疫反应提供了一种新手段。
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