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-nucleotide phosphodiesterase
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  5′-核苷酸磷酸二酯酶
     The Diagnostic Value of 5'-Nucleotide Phosphodiesterase Isoenzyme in Differentiating Malignant from Unmalignant Ascites
     5′-核苷酸磷酸二酯酶同工酶鉴别良恶性腹水的诊断价值
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  “5 '-nucleotide phosphodiesterase”译为未确定词的双语例句
     Evaluation of the combined assay of 5'-nucleotide phosphodiesterase V and alpha fetoprotein in the diagnosis of primary hepatic carcinoma
     5′核苷酸磷酸二酯酮同工酶V和甲胎蛋白联检对肝癌诊断意义的评价
短句来源
     THE RELATIONSHIP BETWEEN THE DAMAGE OF RAT'S KIDNEY INDUCED BY DDP AND THE CHANGE OF 5'-NUCLEOTIDE PHOSPHODIESTERASE IN URINE
     顺铂致大鼠肾损害与尿5'-核苷酸磷酸二酯酶的关系
短句来源
     5'-nucleotide phosphodiesterase (5'-NPD) isoenzyme was measured in 37 cases with malignant ascites (MA) and 35 cases with unmalignant ascites (UMA). The positive rate of 5'-NPD-Ⅴ and Ⅵ in MA were significantly higher than that in UMA(P<0.01).
     对37例恶性腹水和35例良性腹水测定5′-NPD同工酶,结果表明:恶性腹水中5′-NPI)-Ⅴ和Ⅵ的阳性率明显高于良性腹水(P<0.01)。 特异性分别为80%和74.3%;
短句来源
     THE SIGNIFICANCE OF γ-GLUTAMYL TRANSPEPTIDASE (γ-GTP) AND 5'-NUCLEOTIDE PHOSPHODIESTERASE(5'-NPDase) IN THE DIAGNOSIS OF HEPATOCELLULAR CARCINOMA
     r-谷氨酰转肽酶与5'-核苷酸磷酸二酯酶两种同功酶检查对原发性肝癌诊断价值的探讨
短句来源
  相似匹配句对
     THE PREPARATION OF IMMOBLLIZED 5'-PHOSPHODIESTERASE
     固定化5′-磷酸二酯酶的制备
短句来源
     5.As it is.
     5.仍采用原有设备。
短句来源
     5?
     5?
短句来源
     EVALUATION OF 5' NUCLEOTIDE PHOSPHODIESTERASE ISOZYME V FOR THE DIAGNOSIS OF PRIMARY LIVER CANCER
     探讨5′核苷酸磷酸二酯酶同工酶Ⅴ测定对原发性肝癌的诊断价值
短句来源
     Identification and Characterization of PDE5 cGMP-specific Cyclic Nucleotide Phosphodiesterase
     磷酸二酯酶同工酶PDE5的纯化及性质研究
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  -nucleotide phosphodiesterase
The distribution of cyclic 3', 5'-nucleotide phosphodiesterase activity was determined in photoreceptor cells of the flyCalliphora erythrocephala.
      
Cyclic 3', 5'-nucleotide phosphodiesterase: cytochemical localization in photoreceptor cells of the flyCalliphora erythrocephala
      
The cyclic 3'5'-nucleotide phosphodiesterase D3 was purified from Sinorhizobium fredii MAR-1.
      
Purification and characterization of cyclic 3'5'-nucleotide phosphodiesterase D3 from Sinorhizobium fredii MAR-1
      
Cytochemical distribution of cyclic AMP-dependent 3',5'-nucleotide phosphodiesterase in the rat myocardium
      
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Y-Glutamyl transpeptidase (Y-GTP) and 5'-Nucleotide phosphodiesterase (5'-NPDase) isoenzymes were studied in 210 cases of various liver diseases, including 100 cases of hepatocellu-lar carcinoma, 10 metastatic liver carcinoma, 47 liver cirrhosis, 29 chronic hepatitis, 10 acute hepatitis and 14 obstructive jaundice.Y-GTP isoenzyme I', II, II' were found in.7%, 67% and 5% of hepatocellular carcinoma respectively, Y-GTP I could also be found in 2/47 (4%) cases of cirrhosis, and Y-GTP I ' in a case of chronic...

Y-Glutamyl transpeptidase (Y-GTP) and 5'-Nucleotide phosphodiesterase (5'-NPDase) isoenzymes were studied in 210 cases of various liver diseases, including 100 cases of hepatocellu-lar carcinoma, 10 metastatic liver carcinoma, 47 liver cirrhosis, 29 chronic hepatitis, 10 acute hepatitis and 14 obstructive jaundice.Y-GTP isoenzyme I', II, II' were found in.7%, 67% and 5% of hepatocellular carcinoma respectively, Y-GTP I could also be found in 2/47 (4%) cases of cirrhosis, and Y-GTP I ' in a case of chronic hepatitis.5'NPDase V was found, in 28/38 (73.6%) cases of hepaiocellular carcinoma, in 4 out of 6 cases in metastatic liver carcinoma and in 2 out of 10 cases in cirrhosis,Combination of Y-GTP and 5'NPDase isoenzyme positive in 38 cases of hepatocellular carcinoma could raise the positive rate to 97%, and similarly from 63% and 81% to 100% in H cases of hepatocellular carcinoma with normal or low titer of serum AFP.

本文对各种肝脏疾病210例,包括原发性肝癌100例,转移性肝癌10例,肝硬化47例,慢性肝炎29例,急性肝炎10例和阻塞性黄疸14例,分别进行r-谷氨酰转肽酶(γ-GT)、5’-核苷磷酸二酯酶(5’-NPDase)同功酶测定。 γ-GT同功酶Ⅰ’、Ⅱ、Ⅱ’带主要是见于原发性肝癌组,100例中67例有Ⅰ’、Ⅱ、Ⅱ’带,占67%;有Ⅰ’带者7例,占7%;有Ⅱ’带者5例,占5%;在肝硬化组中有Ⅱ带者2例,占4%(2/47);一例郁胆性肝炎出现Ⅰ’带,占3%(1/29)。 38例原发性肝癌中28例出现5’-NPDase同功酶Ⅴ带。占73.6%;转移性肝癌6例中4例有Ⅴ带,占66%;肝硬化中有2例出现Ⅴ带,占10%(2/20)。 原发性肝癌AFP阴性和低滴度阳性者11例。其中出现γ-GT-Ⅱ带者7例,占63%,出现5’-NPDase-Ⅴ带者9例,占81%。若将r-GTⅡ带和5’-NPDase-Ⅴ带互相补充,可提高阳性率100%。

5′-nucleotide phosphodiesterase is-oenzymes have been separated from theserum of human hepatocellular carcinomaon 4-20% tubular polyacrylamide gelgradient electrophoresis showing ele-ven isoenzymes in which Band Ⅰ ,Ⅴ andⅥ (from anode to cathode) are allabsent in 125 normal sera.Band Ⅴ and Ⅵwere detectable in 31 (73.8% ) of 42patients with hepatocellular carcinomabut absent in 70 cases of other diseases.Therefore, Band Ⅴ and Ⅵ are possiblyspecific isoenzyme bands of primary liv-er cancer and might be a...

5′-nucleotide phosphodiesterase is-oenzymes have been separated from theserum of human hepatocellular carcinomaon 4-20% tubular polyacrylamide gelgradient electrophoresis showing ele-ven isoenzymes in which Band Ⅰ ,Ⅴ andⅥ (from anode to cathode) are allabsent in 125 normal sera.Band Ⅴ and Ⅵwere detectable in 31 (73.8% ) of 42patients with hepatocellular carcinomabut absent in 70 cases of other diseases.Therefore, Band Ⅴ and Ⅵ are possiblyspecific isoenzyme bands of primary liv-er cancer and might be a new additon tothe means in the diagnosis of this disea-se. By the same method, also found thatserum abnormal isoenzyme bands of pa-tients with liver cancer corresponded tothose of cord blood sera of the newbornand foetus. It has also been found thatthese abnormal isoenzymes are diminishi-ng gradually after birth and all disape-ar when children reach the age of ten.These findings indicate that the 5′-NPDaseabnormal isoenzymes belong to the carc-inoembryonic isoenzymes in the serum ofpatients with liver cancer.

用4~20%管状聚丙烯酰胺梯度凝胶电泳,分离肝癌病人血清5′-核苷酸磷酸二酯酶同工酶,出现的11条同工酶带中,第Ⅰ、Ⅴ和第Ⅵ条在125例正常人血清中均未出现,而第Ⅴ和第Ⅴ条在42例肝癌中有31例出现,但在70例非肝癌肝病病人中没有1例出现.因此第Ⅴ和第Ⅵ同工酶带可能是肝癌的特异带,会有助于肝癌的诊断。用同法又发现胎儿和新生儿脐带血清中存在着与肝癌病人血清中相对应的异常同工酶带,新生儿出生后这异常的第Ⅰ、Ⅴ和Ⅵ同工酶逐渐减弱,到10岁以后全部消失。这些结果提示肝癌病人血清中出现的5′-核苷酸磷酸二酯酶异常同工酶带属于癌胚同工酶。

The activity of 5'-Nucleotide Phosphodiesterase-V in the serum was measur- ed in 15 mid-and late-gestation fetuses, 100 first-, second- and third-trimester pregnant women and 67 normal, persons. The rusults suggest that this isoenzyme is of an embryonic origin. The enzymatic activity was also measured in 30 cases of hepatoma, 30 cases of acute hepatitis and 43 cases of chronic hepatitis. All patients were HBsAg positive. The results suggest that this isoenzyme has no direct relationship to HBsAg. But it...

The activity of 5'-Nucleotide Phosphodiesterase-V in the serum was measur- ed in 15 mid-and late-gestation fetuses, 100 first-, second- and third-trimester pregnant women and 67 normal, persons. The rusults suggest that this isoenzyme is of an embryonic origin. The enzymatic activity was also measured in 30 cases of hepatoma, 30 cases of acute hepatitis and 43 cases of chronic hepatitis. All patients were HBsAg positive. The results suggest that this isoenzyme has no direct relationship to HBsAg. But it might be correlated to regeneration of liver cell.

作者对15例中、大月份胎儿,100例早、中、晚期孕妇及97例正常人血清作5'-NpDase-V的测定。直接证实了本同工酶的胚胎性来源,对HBsAg阳性的30例肝癌,30例急性肝炎和43例慢性肝炎亦作本同工酶测定,结果说明本同工酶与HBsAg无直接关联,但可能与肝细胞再生有关。

 
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