助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   upstream regulation region 的翻译结果: 查询用时:0.034秒
图标索引 在分类学科中查询
所有学科
基础医学
更多类别查询

图标索引 历史查询
 

upstream regulation region
相关语句
  上游调控序列
     Identification of 5-flank upstream regulation region of CD226
     CD226基因5′上游调控序列研究
短句来源
     Objective:To identify the function of the 5′-flank upstream regulation region of human CD226 gene.
     目的:研究CD226基因5′上游调控序列对CD226基因表达调控的影响。
短句来源
     Methods:The upstream regulation region of CD226 was cloned by PCR and ligated into pGL3 vector.
     方法:通过基因克隆的方法将CD226基因5′上游调控序列,克隆到荧光素酶报告基因载体中(pGL3basic),用脂质体转染Jurkat细胞,48小时后检测荧光素酶活性。
短句来源
     Aim To identify the promoter sequence and 5' terminal upstream regulation region of CD226. Methods We predict promoter sequence and 5'-terminal regulation region by software, then analysis one single nucleic acid polymorphism site in open reading frame of CD226 by sequencing.
     目的 研究人CD2 2 6 (PTA1)启动子及其 5’上游调控序列。 方法 应用计算机软件预测启动子序列 ,并分析人CD2 2 6基因 5’上游调控序列以及通过RT -PCR的方法研究开放读框中的单核苷酸多态性。
短句来源
  “upstream regulation region”译为未确定词的双语例句
     METHODS: Bioinformatic analysis was performed on the upstream regulation region of ndrg 2 gene and the second structure of NDRG2 protein.
     方法 :运用internet网络上的数据库及程序 ,对ndrg2基因的调控区和NDRG2蛋白的二级结构进行生物信息学分析 .
短句来源
  相似匹配句对
     Study on the engineering of channel regulation in upstream Hanjiang River
     韩江上游(梅江、汀江)航道整治工程试验研究
短句来源
     REGULATION OF HBV GENE EXPRESSION BY CORE PROMOTER AND ITS UPSTREAM SEQUENCE
     乙型肝炎病毒核心启动子及其上游顺序对其基因表达的调控
短句来源
     Regulation and Control
     约束与控制
短句来源
     On Legal Regulation
     论法律调整
短句来源
     Identification of 5-flank upstream regulation region of CD226
     CD226基因5′上游调控序列研究
短句来源
查询“upstream regulation region”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
没有找到相关例句


Aim To identify the promoter sequence and 5' terminal upstream regulation region of CD226. Methods We predict promoter sequence and 5'-terminal regulation region by software, then analysis one single nucleic acid polymorphism site in open reading frame of CD226 by sequencing. Results We get two possible promoter sequence of CD226 and some putative nuclear factor binding sites through which nuclear factors may play some role in it, such as AP-1, Ets-1, Sp1, P300, PU.1 and PEA3. There is...

Aim To identify the promoter sequence and 5' terminal upstream regulation region of CD226. Methods We predict promoter sequence and 5'-terminal regulation region by software, then analysis one single nucleic acid polymorphism site in open reading frame of CD226 by sequencing. Results We get two possible promoter sequence of CD226 and some putative nuclear factor binding sites through which nuclear factors may play some role in it, such as AP-1, Ets-1, Sp1, P300, PU.1 and PEA3. There is one SNP site in the cytoplasmic part of CD226. Conclusion The expression of CD226 may be subtly regulated by many transcription factors and 5' upstream regulator sequence.

目的 研究人CD2 2 6 (PTA1)启动子及其 5’上游调控序列。方法 应用计算机软件预测启动子序列 ,并分析人CD2 2 6基因 5’上游调控序列以及通过RT -PCR的方法研究开放读框中的单核苷酸多态性。结果 CD2 2 6基因在 -375bp处和 - 130bp处可能有两个启动子 ,含有AP - 1、Ets- 1、Sp1、P30 0、PU .1、PEA3等转录因子结合序列 ,在编码胞浆区的序列中存在一个单核苷酸多态性位点。结论 CD2 2 6基因表达受到多种转录因子和 5’端上游调控序列的调控。

AIM: To obtain some functional clues from the structures of ndrg 2 gene and NDRG2 protein. METHODS: Bioinformatic analysis was performed on the upstream regulation region of ndrg 2 gene and the second structure of NDRG2 protein. RESULTS: Several binding sequences of some different transcription factors were found and these factors were involved in the regulation of tissue specific gene expression, the expression of genes related to growth and early development of cells and the expression...

AIM: To obtain some functional clues from the structures of ndrg 2 gene and NDRG2 protein. METHODS: Bioinformatic analysis was performed on the upstream regulation region of ndrg 2 gene and the second structure of NDRG2 protein. RESULTS: Several binding sequences of some different transcription factors were found and these factors were involved in the regulation of tissue specific gene expression, the expression of genes related to growth and early development of cells and the expression of genes under some stimulated conditions. The results of protein fold classification showed that NDRG2 belonged to alpha/beta hydrolase fold family and high similarity was found between NDRG2 and epoxide hydrolase of bacteria. CONCLUSION : NDRG2 protein may be involved in resisting the oxidative stress, maintaining the balance of cell redox potential and regulating the metabolism process of xenobiotics or intracellular toxic molecules, which is very useful in further exploring the precise functions of NDRG2 protein.

目的 :对ndrg2 (n mycdownsreamregulatorgene 2 )基因调控区和NDRG2蛋白序列进行生物信息学分析 ,从结构上预测其功能 .方法 :运用internet网络上的数据库及程序 ,对ndrg2基因的调控区和NDRG2蛋白的二级结构进行生物信息学分析 .结果 :ndrg2基因调控区存在多种转录因子结合位点 ,功能主要涉及组织特异性表达调控 ,细胞生长发育相关基因和应激反应基因的表达调控等 ;NDRG2蛋白的结构属于α/β水解酶类折叠 ,其分类预测表明与细菌环氧化物水解酶的二级结构极为相似 .结论 :生物信息学分析提示NDRG2蛋白具有一定的酶活性 ,可能参与细胞抗氧化应激反应 ,内外源有毒物质的代谢 ,维持细胞内氧还电势平衡等

Objective:To identify the function of the 5′-flank upstream regulation region of human CD226 gene.Methods:The upstream regulation region of CD226 was cloned by PCR and ligated into pGL3 vector. Then the vector was transfected into Jurkat cell and luciferase activity was detected after 48 h culture.Results:CD226 gene may have two promoters, P1 and P2,which were located at the region of -843--319 bp and +1-+181 bp respectively, and PMA can up-regulate P1 while down-regulate P2. Both P1 and P2...

Objective:To identify the function of the 5′-flank upstream regulation region of human CD226 gene.Methods:The upstream regulation region of CD226 was cloned by PCR and ligated into pGL3 vector. Then the vector was transfected into Jurkat cell and luciferase activity was detected after 48 h culture.Results:CD226 gene may have two promoters, P1 and P2,which were located at the region of -843--319 bp and +1-+181 bp respectively, and PMA can up-regulate P1 while down-regulate P2. Both P1 and P2 can be up-regulated by A23187, especially P2.Conclusion:CD226 gene may have two promoters, and PMA and A23187 can regulate CD226 promoter activity in the similar pattern of protein level.

目的:研究CD226基因5′上游调控序列对CD226基因表达调控的影响。方法:通过基因克隆的方法将CD226基因5′上游调控序列,克隆到荧光素酶报告基因载体中(pGL3basic),用脂质体转染Jurkat细胞,48小时后检测荧光素酶活性。结果:CD226基因存在两个启动子P1和P2,分别位于与-843~-319bp和+1~+181bp,PMA可以上调P1的启动子活性,对P2有一定的抑制作用;A23187均可以上调两个启动子的活性,但对P2的作用更为明显。结论:CD226基因存在两个启动子,其活性受到PMA和A23187的调控,并呈与蛋白水平表达调控相类似的模式。

 
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关upstream regulation region的内容
在知识搜索中查有关upstream regulation region的内容
在数字搜索中查有关upstream regulation region的内容
在概念知识元中查有关upstream regulation region的内容
在学术趋势中查有关upstream regulation region的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社