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second primary malignancy
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  “second primary malignancy”译为未确定词的双语例句
     Clinical Course Of Patients with Small Cell Lung Cancer As Second Primary Malignancy
     小细胞肺癌作为第二原发肿瘤的临床特征(英文)
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  相似匹配句对
     Second .
     二、破自造论。
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     Second,
     二是对于?
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     Radiation-induced second primary tumors
     辐射诱发的二重癌
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     Second part is the primary part of the thesis.
     论文的第一部分是背景介绍。
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     Primary Myelofibrosis
     原发性骨髓纤维化(附5例报告)
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  second primary malignancy
Squamous Cell Esophageal Carcinoma as a Second Primary Malignancy in a Woman with Epithelial Ovarian Cancer
      
Cerebral primitive neuro-ectodermal tumour (PNET) occurring as a second primary malignancy in childhood is exceedingly rare.
      
Of 949 patients included in the study, 189 (20%) developed a metachronous second primary malignancy, most frequently in the aerodigestive tract.
      
In 69 patients (12.4%) a lung malignancy was diagnosed, with 28 having a histologically confirmed second primary malignancy.
      
A delayed presentation makes distinction from an anterior mediastinal mass problematic in view of the increased risk of a second primary malignancy in pediatric cancer survivors.
      
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Among 17250 cases of cervical canser treated at Shanghai Cancer Hospital from1962 to 1989, 59 were found to have developed multiple primary malignant tumors and71.2% of them had their second primary malignancies at the female gentital tract andgastrointestinal tract. Fifty six cases were found to have second primary carcinomasafter treatment of cervical cancer and three were before. The carcinogenic factors werediscussed. The combination of surgery, radiotherapy and chemotherapy was used...

Among 17250 cases of cervical canser treated at Shanghai Cancer Hospital from1962 to 1989, 59 were found to have developed multiple primary malignant tumors and71.2% of them had their second primary malignancies at the female gentital tract andgastrointestinal tract. Fifty six cases were found to have second primary carcinomasafter treatment of cervical cancer and three were before. The carcinogenic factors werediscussed. The combination of surgery, radiotherapy and chemotherapy was used in themanagement of the second primary carcinomas. In this series, the three and five-yearsurvival rates were 35.3% and 21%, respectively.

本文报道我院1962~1989年收治59例宫颈癌伴发其他原发癌,结合文献对其病因、发生部位和治疗进行讨论。多原发癌71.2%发生在生殖系统和消化系统,该两系统是多原发癌的易感器官,由于原发癌和复发转移癌两者处理预后截然不同,第二原发癌如能及时发现、正确处理,采用手术或放疗,辅以化疗,疗效良好。本文病例三年、五年生存率分别为35.3%及21%。

Objective To discuss the development, treatment and prognosis of a second primary lung cancer in laryngeal carcinoma patients. Methods A total of 36 patients with a second primary lung cancer was discovered in 2 182 laryngeal cancer patients. For comparison, a group of 15 541 lung cancers was also reviewed for the presence of a second primary laryngeal cancer. All patients have been followed for over five years. Results From 1958 to 1999, out of 2 182 laryngeal carcinoma...

Objective To discuss the development, treatment and prognosis of a second primary lung cancer in laryngeal carcinoma patients. Methods A total of 36 patients with a second primary lung cancer was discovered in 2 182 laryngeal cancer patients. For comparison, a group of 15 541 lung cancers was also reviewed for the presence of a second primary laryngeal cancer. All patients have been followed for over five years. Results From 1958 to 1999, out of 2 182 laryngeal carcinoma patients, 36 synchronous (3) or metachronous (33) second primary malignancies of the lung were found. This represented 1.65% of all largngeal cancers observed or 45.0% of all the second primary cancers developed. Their pathology was: squamous cell carcinoma(32 88.9%), adenocarcinoma(2 5.6%), small cell carcinoma(1 2.8%) and large cell carcinoma (1 2.8%). The c TNM stages were: stageⅠ (7 19.4%), stageⅡ(12 33.3%), stageⅢ(9 25.0%) and stageⅣ(8 22.2%). The 2 and 5 year survival rates were 41.7% and 8.3%, with an average survival of 23 months. The interval from the treatment of the initial laryngeal carcinoma to the development of the new second primary carcinoma of lung ranged from 1 to 14 years, with an average of 44 months. Conclusion Synchronous or metachronous second malignancies of the lung are sometimes encountered in laryngeal cancer patients while the occurrence of a laryngeal second primary following a lung cancer is not observed. The development of the second primary lung cancer is not related to the treatment of the initial laryngeal malignancies. Surgery plus external radiotherapy provides better results than surgery or radiotherapy alone.

目的 探讨喉癌患者以肺癌为表现的第二原发癌的发病情况、治疗方法及预后。方法总结 2 182例喉癌患者中出现的 36例第二原发肺癌 ,回顾分析喉癌的治疗 (分为单一放疗、单一手术、手术 +放疗 )对发生第二原发肺癌的影响 ,及第二原发肺癌的治疗情况和预后。随访患者均超过 5年 ,随诊率为 10 0 %。生存率用寿命表法计算。结果  36例第二原发肺癌 ,占喉癌患者总例数的1.7% (36 /2 182 ) ;占喉癌第二原发癌的 45 .0 % (36 /80 ) ,而同期 15 5 41例肺癌患者中 ,则没有在喉部发生第二原发癌者。第二原发肺癌多在喉癌确诊后平均 44个月 (1~ 14年 )时发现。 36例中 ,鳞癌 32例 ,腺癌 2例 ,小细胞未分化癌 1例 ,大细胞未分化癌 1例。第二原发肺癌平均生存 2 3个月 ,2年生存率为 41.7% ,5年生存率为 8.3%。结论 喉癌的第二原发癌以肺癌为最多 ,而肺癌很少出现第二原发喉癌。喉癌的治疗方法对肺癌的发生与否及发生时机影响不大 ,手术 +放疗优于单一手术及单一放疗。

Objective:To evaluatc the clinical courrse of patients with small cell lung cancer(SCLC)as second primary malignancy.Methods:Among thc 355 patients diagnosed with SCLC at Helen and Harry Gray Cancer Center of Hartford Hospital Connecticut USA between 1988 and 1998,the records of 48 patients,which had been diagnosed with other malignancies before their diagnosis of SCLC,were retro- spectively reviewed.Results:Forty-eight patients(13.5%)were diagnosed with other malignancies prior to their SCLC...

Objective:To evaluatc the clinical courrse of patients with small cell lung cancer(SCLC)as second primary malignancy.Methods:Among thc 355 patients diagnosed with SCLC at Helen and Harry Gray Cancer Center of Hartford Hospital Connecticut USA between 1988 and 1998,the records of 48 patients,which had been diagnosed with other malignancies before their diagnosis of SCLC,were retro- spectively reviewed.Results:Forty-eight patients(13.5%)were diagnosed with other malignancies prior to their SCLC among which 43 had documented smoking history and 93% of them(40/43)were cur- rent/former smokers.Of the 28-second primary SCLC patients who were treated with standard method, 11(39.3%)achieved CR,12(42.8%)achieved PR,and the RR was 82.1%.The median survival of the 28 treated with standard method was 11.3 months(5.1-77.7 months),while that of the rest 19 untreated patients(1 of 20 was lost to follow-up)was only 2.0 months(0.5-34.0 months).There was no significant difference in the median survival and RR between 165 treated first primary SCLC(13.5 months and 77.6% respectively)and 28 treated secondary primary SCLC(11.3 months and 82.1% respectively)(P>0.05). The patients who had prostate cancer were older and subjected to less treatments than those with skin cancer,so their survival was shorter than the latter(3.5 months vs.15 months,P<0.05).Conclusion: The response and survival of the treated patients with SCLC as a second malignancy showed no difference as compared to the treated ones with SCLC only.Therefore,an active medical treatment is important to relieve symptom and prolong survival of the second primary SCLC patients.

目的探讨小细胞肺癌作为第二原发肿瘤的临床特征。方法回顾分析美国康州 Hartford 医院 Helen & Harry Gray 癌症中心10年诊治的355例小细胞肺癌,其中经正规治疗者165例。作为第二原发肿瘤发生于其他恶性肿瘤之后的小细胞肺癌48例,经正规治疗者28例。结果 48例小细胞肺癌诊断之前患有其他恶性肿瘤,占13.5%,其中包括头颈部癌4例(8.3%),皮肤癌11例(22.9%,其中2例为三原发肿瘤),非小细胞肺癌2例(4.2%),乳腺癌6例(12.5%),胃肠肿瘤5例(10.4%),妇科肿瘤3例(6.3%),男性泌尿生殖道肿瘤5例(10.4%),前列腺癌13例(27.1%),血液系统肿瘤2例(4.2%)。三原发肿瘤5例(10.4%)。有吸烟史者93%(40/43例)。发生在前列腺癌后的患者与发生在皮肤癌后的患者相比,年龄较大,正规治疗者较少,生存期较短(分别为3.5月和15月)。在28例正规治疗患者中,11例完全缓解(39.3%),12例部分缓解(42.9%),其生存期为5.1~77.7月(中位1 1.3月);20例未治疗患者的生存期为0.5~34.0月(中位2.0月)。165例经正规治疗过的...

目的探讨小细胞肺癌作为第二原发肿瘤的临床特征。方法回顾分析美国康州 Hartford 医院 Helen & Harry Gray 癌症中心10年诊治的355例小细胞肺癌,其中经正规治疗者165例。作为第二原发肿瘤发生于其他恶性肿瘤之后的小细胞肺癌48例,经正规治疗者28例。结果 48例小细胞肺癌诊断之前患有其他恶性肿瘤,占13.5%,其中包括头颈部癌4例(8.3%),皮肤癌11例(22.9%,其中2例为三原发肿瘤),非小细胞肺癌2例(4.2%),乳腺癌6例(12.5%),胃肠肿瘤5例(10.4%),妇科肿瘤3例(6.3%),男性泌尿生殖道肿瘤5例(10.4%),前列腺癌13例(27.1%),血液系统肿瘤2例(4.2%)。三原发肿瘤5例(10.4%)。有吸烟史者93%(40/43例)。发生在前列腺癌后的患者与发生在皮肤癌后的患者相比,年龄较大,正规治疗者较少,生存期较短(分别为3.5月和15月)。在28例正规治疗患者中,11例完全缓解(39.3%),12例部分缓解(42.9%),其生存期为5.1~77.7月(中位1 1.3月);20例未治疗患者的生存期为0.5~34.0月(中位2.0月)。165例经正规治疗过的第一原发 SCLC 的中位生存期(13.5月)、缓解率(77.6%)与28例第二原发 SCLC(11.3月,82.1%)均无显著差异。(P>0.05)。结论小细胞肺癌作为第二原发肿瘤的发生率为13.5%,其中三原发肿瘤为10.4%。其治疗有效率和生存期与一般小细胞肺癌均无差异。发生在前列腺癌后的患者可能比发生在皮肤癌后的患者预后差。

 
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