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acute icteric hepatitis b
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  “acute icteric hepatitis b”译为未确定词的双语例句
     In comparision with acute icteric hepatitis B(n=11)and chronic active hepatitis B(n=28),the CD8+ cells in patients with severe hepatitis B were markedly hig-her and CD4+/CD8+ ratios markedly lower.
     相反,非HBV感染性肝病患者非T细胞和CD_4~+细胞增加,CD_4~+/CD_8~+比值>1。
短句来源
     Of 46 cases with acute icteric hepatitis B diagnosed on the clinical ground, 24 were IgM anti-HBc negative by this kit. Follow-up showed that these cases were actually chronic asymptomatic HBV carriers with an acute episode.
     在46例临床诊断为急性黄疸型乙型肝炎中,24例IgM抗HBc阴性,随访表明为慢性无症状乙肝病毒携带者的急性症状发作.
短句来源
     Objective To observer the therapeutic efficacy of ahylysantinfarctase injection in acute icteric hepatitis B (AIHB).
     目的观察腹蛇抗酶治疗急性黄疸型乙肝炎的疗效。
短句来源
  相似匹配句对
     Acute Infectious Hepatitis
     急性传染性肝炎
短句来源
     STUDY OF ANTI HEV IN CHILDREN WITH ACUTE ICTERIC HEPATITIS.
     成都地区小儿急性黄疸型肝炎HEV感染研究
短句来源
     Acute icteric viral hepatitis was the main clinical type .
     急性黄疸型肝炎是主要的临床类型。
短句来源
     Serological Analysis of284 Patients with Acute Icteric Hepatitis
     急性黄疸型肝炎284例血清学分析
短句来源
     Ultrasonic Image of gallbladder Wall's Change in Acute Icteric Hepatitis
     急性黄疸型肝炎胆囊壁改变超声显像观察
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  acute icteric hepatitis b
On the contrary, two surgeons who omitted the third dose of vaccine developed acute icteric hepatitis B two years later.
      


CORAB-M ( Abbott, USA ) is a specially prepared kit, which is not very sensitive and only able to detect high titer of IgM anti-HBc. Of 46 cases with acute icteric hepatitis B diagnosed on the clinical ground, 24 were IgM anti-HBc negative by this kit. Follow-up showed that these cases were actually chronic asymptomatic HBV carriers with an acute episode. The detection of IgM anti-HBc among the individuals with chronic HBV infection by a kit routinely prepared by ourselves was correlated with activity...

CORAB-M ( Abbott, USA ) is a specially prepared kit, which is not very sensitive and only able to detect high titer of IgM anti-HBc. Of 46 cases with acute icteric hepatitis B diagnosed on the clinical ground, 24 were IgM anti-HBc negative by this kit. Follow-up showed that these cases were actually chronic asymptomatic HBV carriers with an acute episode. The detection of IgM anti-HBc among the individuals with chronic HBV infection by a kit routinely prepared by ourselves was correlated with activity of liver inflammatory process. The results showed that IgM anti-HBc was implicated in the immune response to viral replication in liver.

CORAB-M(Abbott,USA)是经特殊标定的试剂盒,只能检出很高滴度的IgM抗HBc.在46例临床诊断为急性黄疸型乙型肝炎中,24例IgM抗HBc阴性,随访表明为慢性无症状乙肝病毒携带者的急性症状发作.用未经特殊处理自行组成的试剂盒检测处于病毒复制时相的慢性乙肝病毒感染者,IgM抗HBc的检出率与肝组织病变的活动性相平行.上述结果表明:IgM抗HBc能较好反映对病毒复制的组织免疫应答,即病变活动性.

T lymphocyte subsets in the infiltrating cells in the areas of massive or submassive necrosis of patients(n=21)with severe B-viral hepatitis were investigated using monoclonal antibodies(McAb)against human T lymphocyte surface antigen--CD3,CD4, CD8 by avidin-biotin-peroxidase complex technique(ABC). More than 70% of infiltrating cell type were CD3+cells(total T lymphocytes), in which the majority were the CD8+(suppressor /cytotoxic)cells. CD4+(inducer/holper)cells were decreased and CD4+/CD8+ ratios...

T lymphocyte subsets in the infiltrating cells in the areas of massive or submassive necrosis of patients(n=21)with severe B-viral hepatitis were investigated using monoclonal antibodies(McAb)against human T lymphocyte surface antigen--CD3,CD4, CD8 by avidin-biotin-peroxidase complex technique(ABC). More than 70% of infiltrating cell type were CD3+cells(total T lymphocytes), in which the majority were the CD8+(suppressor /cytotoxic)cells. CD4+(inducer/holper)cells were decreased and CD4+/CD8+ ratios were reduced markedly. In comparision with acute icteric hepatitis B(n=11)and chronic active hepatitis B(n=28),the CD8+ cells in patients with severe hepatitis B were markedly hig-her and CD4+/CD8+ ratios markedly lower. By contrast, inpatients with liver diseases (n=5) without HBV infection, the number of non-T and CD4+ cells were increased, CD4+/CD8+ ratios were more than 1. These data suggested that T lymphocytes might play an important role in the mechanism leading to tissue injury. The subpopulation, CD8+ cells may be one of the important immunological factors resulted in destruction of hepatocytes.A fair number of HLA-DR (Human Leucocyte Antigen-DR) positive lymphocytes and hepatocytes and close apposition between infiltrating lymphocytes and membranous HBAg( + ) hepatocytes could be observed.

本文用抗CD_3,CD_4,CD_8McAb和ABC法检测21例重型乙肝患者肝大片,亚大片坏死区炎性浸润细胞中的T细胞亚群,CD_3~+细胞>70%,其中主要为CD_8~+细胞,CD_4~+细胞减少,CD_4~+/CD_8~+比值显著下降,与急黄肝和慢活肝比较差异显著。相反,非HBV感染性肝病患者非T细胞和CD_4~+细胞增加,CD_4~+/CD_8~+比值>1。提示重肝时T细胞可能参与了肝损伤,CD_8细胞亚群可能是介导肝细胞坏死的重要因素之一。还观察到相当数量的淋巴细胞和肝细胞HLA—DR抗原阳性,淋巴细胞与膜型HBAg(+)肝细胞密切接触。

Objective To investigate the relationship between B 7-1 expression and liver damage of patients with hepatitis B. Methods Consecutive paraffin sections were immunohistochemically stained with anti-B 7-1 and anti-HBs monoclonal antibodies, respectively. Results It was observed that B 7-1 antigen expressed variously in the cytoplasm of hepatocytes. In chronic persistent hepatitis B(CPH) group, B 7-1 expressed negatively in 1, mildly in 8, moderately...

Objective To investigate the relationship between B 7-1 expression and liver damage of patients with hepatitis B. Methods Consecutive paraffin sections were immunohistochemically stained with anti-B 7-1 and anti-HBs monoclonal antibodies, respectively. Results It was observed that B 7-1 antigen expressed variously in the cytoplasm of hepatocytes. In chronic persistent hepatitis B(CPH) group, B 7-1 expressed negatively in 1, mildly in 8, moderately in 5, and strongly in 3 samples, respectively. In contrast, in chronic active hepatitis B(CAH) group, B 7-1 expressed mildly in 2, moderately in 3 and strongly in 9 samples, respectively. There was statistical difference between the two groups by Wilcoxon's test. One subacute fulminant and 1 acute icteric hepatitis B(AIH) samples expressed mildly. Hepatitis B surface antigen (HBsAg) expressed in 33 of 34 samples with different levels, mostly expressing moderately to markedly and in the cytoplasm of hepatocytes, a few both in the cytoplasm and on the membrane. Conclusion (1) B 7-1 expressed in the liver tissues might be induced by HBV infection and its expression was closely correlated with the activity of viral hepatitis B. (2) There was no direct relationship between B 7-1 expression and the level of HBsAg expression. (3) Like other adhesion molecules, B 7-1 expression in liver tissue with HBV infection was probably one of the evidences that hepatocytes were activated and actively involved in the immune regulation during HBV infection.

目的阐明B7-1在乙型肝炎肝组织中的表达及其与病变发生、发展的关系。方法用免疫组织化学方法检测连续切片的乙型肝炎肝组织B7-1及表面抗原表达。结果正常对照2例均为阴性;17例慢性迁延性肝炎(CPH)中,胞浆B7-1阳性的有16例,轻度阳性8例,中度5例,重度3例;14例慢性活动性肝炎(CAH)全部阳性,其中轻度阳性2例,中度3例,重度9例,经等级秩和检验,两者差异显著(P<001)。急性黄疸性肝炎、亚急性重型肝炎轻度阳性。在34例乙型肝炎肝组织中,33例HBsAg阳性,轻度阳性3例,其余为中到重度阳性,且CPH与CAH两组之间无统计学差异。结论(1)乙型肝炎病毒感染可诱导B7-1在肝组织表达,且表达强弱与肝炎病变程度正相关;(2)乙型肝炎表面抗原在组织中表达强弱与B7-1表达无关。(3)B7-1在肝组织中的表达可能是肝细胞活化积极参与免疫反应的佐证。

 
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