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glucose turnover
相关语句
  葡萄糖周转速度
     INFLUENCE OF RUMINAL ACETATE TO PROPIONATE RATIO ON GLUCONEOGENESIS OF PROPIONATE AND GLUCOSE TURNOVER IN SHEEP
     不同瘤胃乙、丙酸比例对绵羊丙酸糖异生和葡萄糖周转速度的影响
短句来源
     C-labelled propionate and -14C-glucose were used as a tracer to measure the percentage of glucose carbon from propionate and glucose turnover of the sheep sustained by intragastric nutrition when volatile fatty acid mixtures with three acetate to propionate ratios were infused.
     本项试验使用了 14C标记的丙酸和葡萄糖 ; 用同位素示踪技术研究了全营养灌注绵羊改变瘤胃灌注混合挥发性脂肪酸中乙/丙酸比例后 ,丙酸糖异生代谢和体内葡萄糖周转速度的变化。
短句来源
  葡萄糖周转
     INFLUENCE OF RUMINAL ACETATE TO PROPIONATE RATIO ON GLUCONEOGENESIS OF PROPIONATE AND GLUCOSE TURNOVER IN SHEEP
     不同瘤胃乙、丙酸比例对绵羊丙酸糖异生和葡萄糖周转速度的影响
短句来源
     C-labelled propionate and -14C-glucose were used as a tracer to measure the percentage of glucose carbon from propionate and glucose turnover of the sheep sustained by intragastric nutrition when volatile fatty acid mixtures with three acetate to propionate ratios were infused.
     本项试验使用了 14C标记的丙酸和葡萄糖 ; 用同位素示踪技术研究了全营养灌注绵羊改变瘤胃灌注混合挥发性脂肪酸中乙/丙酸比例后 ,丙酸糖异生代谢和体内葡萄糖周转速度的变化。
短句来源
  “glucose turnover”译为未确定词的双语例句
     Methords An extended hyperinsulinemic euglycemic clamp technique with 3-3H labelled glucose as a tracer was applied in conscious rats to investigate the time course of plasma free fatty acids(FFA), insulin levels and glucose turnover during the insulin clamp.
     方法 采用3-3H标记葡萄糖作为示踪剂建立自由状态下大鼠扩展高胰岛素—正常血糖钳夹技术,并动态观察其体内糖代谢的改变及血浆游离脂肪酸(FFA)和胰岛素(Ins)浓度随时间变化的过程。
短句来源
     Euglycemic hyperinsulinemic clamp studies were established in awake, unstressed rats with 6,6 D 2 glucose as a tracer . Time course of plasma free fatty acids (FFA), insulin levels and glucose turnover were estimated during euglycemic clamp study .
     采用 6 ,6 D2 葡萄糖作为示踪剂 ,建立了自由状态下大鼠正常血糖 -高胰岛素钳夹术 ,并动态观察了其体内糖代谢的动态改变及血浆游离脂肪酸 (FFA)和Ins浓度随时间变化的过程。
短句来源
     Glucose turnover was decided by gas chromatograph mass spectrometer (GC-MS).
     采用气相色谱 -质谱仪 (GC -MS)测定糖代谢率。
短句来源
     Glucose turnover was determind with by gas chromatograph mass spectrometer (GC MS).
     采用气相色谱 -质谱仪 (GC MS)测定糖代谢率。
短句来源
  相似匹配句对
     TURNOVER OF ~(14)C-GLUCOSE IN SOILS AND ITS RELATIONSHIP WITH SOIL CHARACTERS
     土壤中~(14)C-葡萄糖的周转及其与土壤特性的关系
短句来源
     glucose 3;
     葡萄糖 ,3;
短句来源
     The turnover of 14 C\|glucose added in 13 soils was studied.
     研究了1 4 C 葡萄糖在 1 3种土壤中的周转。
短句来源
     Separation of Fructose and Glucose
     果糖与葡萄糖的分离
短句来源
     Price Indices & Turnover
     股价指数及成交统计
短句来源
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  glucose turnover
Glucose turnover time was inversely related to integral algal production (r = -0.72, n = 70, p >amp;lt; 0.001) and less strongly to bacterial numbers.
      
Vmax, maximum glucose concentration (Kt + Sn) and glucose turnover time (Tt) were usually highest at the surface and decreased with depth concomitant with algal production.
      
Very low summertime 3H-glucose turnover times of 5 h increased to a level of 10-20 h from August to January.
      
Glucose carbon recycling, glucose production and glucose turnover in glycogen storage disease type I and type II patients and control subjects were determined by a novel approach - mass isotopomer analysis of plasma13C glucose.
      
The relationship between insulin concentration in plasma and glucose turnover (measured with [3-3H]glucose) was not influenced by the calcemic and vitamin D status of the piglets.
      
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C-labelled propionate and -14C-glucose were used as a tracer to measure the percentage of glucose carbon from propionate and glucose turnover of the sheep sustained by intragastric nutrition when volatile fatty acid mixtures with three acetate to propionate ratios were infused.The three acetate to propionate ratios were 75:15 (VFA1),65:25(VFA2) and 45:45(VFA3),respectively.The percentages of glucose carbon from propionate in blood samples drained from jungular vein of the sheep, when different VFA...

C-labelled propionate and -14C-glucose were used as a tracer to measure the percentage of glucose carbon from propionate and glucose turnover of the sheep sustained by intragastric nutrition when volatile fatty acid mixtures with three acetate to propionate ratios were infused.The three acetate to propionate ratios were 75:15 (VFA1),65:25(VFA2) and 45:45(VFA3),respectively.The percentages of glucose carbon from propionate in blood samples drained from jungular vein of the sheep, when different VFA mixtures were infused, were 29.5±1.05(VFA1),24.35±2.17(VFA2)and 25.21±1.15(VFA3) respectively,with the highest percentage for VFA1 (P<0.01).Glucose turnovers of the sheep,when VFA1 or VFA2 were infused ,were (5.16±0.16) g/h and(4.69±0.08 )g/h respectively,which indicated that when VFA1 was infused,glucose turnover was increased(P<0.01).

本项试验使用了 14C标记的丙酸和葡萄糖 ;用同位素示踪技术研究了全营养灌注绵羊改变瘤胃灌注混合挥发性脂肪酸中乙/丙酸比例后 ,丙酸糖异生代谢和体内葡萄糖周转速度的变化。结果表明 ,灌注乙/丙酸比例为75 :15的混合挥发性脂肪酸时 ,葡萄糖碳原子中来自丙酸的碳原子比例(P<0.01)和体内葡萄糖周转速度(P<0.05)均高于灌注其它乙/丙酸比例的混合挥发性脂肪酸。本研究结果为粗饲料代谢能利用效率低于精饲料是由于体内葡萄糖供给不足的观点提供了依据

To evaluate the insulin sensitivity (insulin stimulated systemic glucose uptake) in vivo . Euglycemic hyperinsulinemic clamp studies were established in awake, unstressed rats with 6,6 D 2 glucose as a tracer . Time course of plasma free fatty acids (FFA), insulin levels and glucose turnover were estimated during euglycemic clamp study . When insulin was infused at a rate of 4.8mU/kg .min, hepatic glucose production (HGP) was completely inhibited while insulin-mediated glucose disappearance...

To evaluate the insulin sensitivity (insulin stimulated systemic glucose uptake) in vivo . Euglycemic hyperinsulinemic clamp studies were established in awake, unstressed rats with 6,6 D 2 glucose as a tracer . Time course of plasma free fatty acids (FFA), insulin levels and glucose turnover were estimated during euglycemic clamp study . When insulin was infused at a rate of 4.8mU/kg .min, hepatic glucose production (HGP) was completely inhibited while insulin-mediated glucose disappearance rate (GRd) was significantly (3.8 fold) increased compared with baseline, and the concentration of FFA was remarkably decreased . The average coefficients of variation in plasma glucose levels, glucose infusion rates (GIR) and glucose disappearance rate (GRd) were 5.76%, 6.25% and 9.17% respectively . The errors of replication in GIR and GRd were 1.2% and 7% . Euglycemic hyperinsulinemic clamp technique in the awake rat using 6,6 D 2 glucose as a tracer were performed with good precision and credibility . This technique excluded the risk of radioactive contamination . During the steady state of exogenous insulin and glucose metabolism, glucose utilization increased while the lipolysis decreased.

为准确地评价在体组织对胰岛素 (Ins)的敏感性及探讨在胰岛素抵抗 (IR)状态下机体糖代谢变化。采用 6 ,6 D2 葡萄糖作为示踪剂 ,建立了自由状态下大鼠正常血糖 -高胰岛素钳夹术 ,并动态观察了其体内糖代谢的动态改变及血浆游离脂肪酸 (FFA)和Ins浓度随时间变化的过程。大鼠在 4 8mU (kg·min)速率Ins输注下 ,血糖稳定在正常水平而肝糖输出被抑制 ,胰岛素介导的机体葡萄糖利用率较基础状态显著增加 ,游离脂肪酸 (FFA)浓度显著下降。本钳夹术平均血糖变异系数为 5 76 %。平均GIR变异系数为 6 2 5 % ,GRd为 9 17%。重复试验GIR与GRd误差范围为 1 2 %和 1 7%。以 6 ,6 D2 葡萄糖作为示踪剂建立的自由状态下的大鼠正常血糖钳夹技术具有准确、可靠 ,无放射污染等优点 ,在外源性胰岛素 -葡萄糖代谢稳定状态下 ,机体对葡萄糖利用显著增加 ,脂肪分解显著减少。

AIM: To investigate the effects of milrinone (a selective phosphdiesterase III inhibitor PDE 3) on insulin secretion, blood glucose, plasma free fatty acids (FFA) and dose-response relationship, and assess possible effects of milrinone on glucose metabolism and insulin sensitivity in conscious rats. METHODS: The catheterized nonstressed rats were administered by the varying doses of milrinone (1, 5, 25 μmol/kg) and were compared with controls. A hyperinsulinaemic- euglycaemic clamp was established...

AIM: To investigate the effects of milrinone (a selective phosphdiesterase III inhibitor PDE 3) on insulin secretion, blood glucose, plasma free fatty acids (FFA) and dose-response relationship, and assess possible effects of milrinone on glucose metabolism and insulin sensitivity in conscious rats. METHODS: The catheterized nonstressed rats were administered by the varying doses of milrinone (1, 5, 25 μmol/kg) and were compared with controls. A hyperinsulinaemic- euglycaemic clamp was established in awake rats, and milrinone(25 μmol/kg) and 25% dimethyl sulfoxide (DMSO, as a control) were given at 120 min during hyperinsulinaemic- euglycaemic clamp. Glucose turnover was decided by gas chromatograph mass spectrometer (GC-MS). RESULTS: After dosing, plasma FFA levels in 3 milrinone groups significantly increased compared with the controls and before dosing. The percentages of elevation of FFA by the different milrinone doses were very similar, 50%, 52%, 55% for 1, 5, 25 μmol/kg respectively at 2 min after dosing. Plasma insulin levels were significantly elevated in the 5 and 25 μmol/kg groups, and the effect of milrinone on glucose concentration was detectable only 25 μmol/kg group. During hyperinsulinaemic clamp, there were significant increase in plasma FFA (from 173.1±15 2 to 633 8±87 3 μEq/L) and hepatic glucose production (HGP), and a significant decrease in glucose infusion rates (GIR) (to about 21%). CONCLUSION: These data suggest that milrinone impaires the abilities of insulin to suppress lipolysis and HGP, and insulin-mediated glucose utilization in peripheral tissue. Therefore, milrinone administration may induce an acute insulin resistance in vivo.

目的 :探讨选择性磷酸二酯酶III(PDE3 )抑制剂米力农 (milrinone)对大鼠胰岛素分泌、血糖、血浆游离脂肪酸 (FFA)的影响和剂量依赖关系 ,及其在胰岛素钳夹状态下对大鼠糖代谢和胰岛素敏感性的影响。方法 :由植入导管给予大鼠不同剂量的米力农 ( 1、5、2 5 μmol/kg)在不同时相测定血糖、血浆FFA和胰岛素水平并与对照组比较。在清醒状态下建立大鼠高胰岛素 -正常血糖钳夹技术 ,并在钳夹 12 0min时分别经导管给予米力农 ( 2 5 μmol/kg)和 2 5 %二甲基亚砜 (DMSO ,对照组 )。采用气相色谱 -质谱仪 (GC -MS)测定糖代谢率。结果 :3个不同剂量米力农组血浆FFA浓度明显高于对照组和给药前 ,在注射后 2min ,各组FFA升高的百分数为 :5 0 %、5 2 %、5 5 % ( 1、5、2 5μmol/kg)。在 5、2 5 μmol/kg组血浆胰岛素水平也明显高于对照组和给药前 ,仅 2 5 μmol/kg组血糖浓度高于对照组和给药前。在胰岛素钳夹研究中 ,米力农处理组大鼠血浆FFA明显高于给药前 ,肝糖输出 (HGP)也明显高于给药前。葡萄糖输注率 ...

目的 :探讨选择性磷酸二酯酶III(PDE3 )抑制剂米力农 (milrinone)对大鼠胰岛素分泌、血糖、血浆游离脂肪酸 (FFA)的影响和剂量依赖关系 ,及其在胰岛素钳夹状态下对大鼠糖代谢和胰岛素敏感性的影响。方法 :由植入导管给予大鼠不同剂量的米力农 ( 1、5、2 5 μmol/kg)在不同时相测定血糖、血浆FFA和胰岛素水平并与对照组比较。在清醒状态下建立大鼠高胰岛素 -正常血糖钳夹技术 ,并在钳夹 12 0min时分别经导管给予米力农 ( 2 5 μmol/kg)和 2 5 %二甲基亚砜 (DMSO ,对照组 )。采用气相色谱 -质谱仪 (GC -MS)测定糖代谢率。结果 :3个不同剂量米力农组血浆FFA浓度明显高于对照组和给药前 ,在注射后 2min ,各组FFA升高的百分数为 :5 0 %、5 2 %、5 5 % ( 1、5、2 5μmol/kg)。在 5、2 5 μmol/kg组血浆胰岛素水平也明显高于对照组和给药前 ,仅 2 5 μmol/kg组血糖浓度高于对照组和给药前。在胰岛素钳夹研究中 ,米力农处理组大鼠血浆FFA明显高于给药前 ,肝糖输出 (HGP)也明显高于给药前。葡萄糖输注率 (GIR)明显低于对照组和给药前。结论 :米力农损害了胰岛素抑制脂解和肝糖输出的能力及胰岛素介导的外周组织糖的利用。因此 ,米力农处理可能在体内诱导了一个急性胰岛素抵抗

 
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