助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   orthotopic injection 的翻译结果: 查询用时:0.199秒
图标索引 在分类学科中查询
所有学科
基础医学
更多类别查询

图标索引 历史查询
 

orthotopic injection
相关语句
  “orthotopic injection”译为未确定词的双语例句
     Differential metastasis-related gene analysis of prostate cancer cells isolated from primary tumor and spontaneous metastases in nude mice with orthotopic injection of PC-3M cells by cDNA microarray
     利用基因芯片法探索人前列腺癌细胞PC-3M在裸鼠体内淋巴道转移相关基因
短句来源
     Methods Patient-like metastatic model was established in female Balb/C mice (n=92) via orthotopic injection of human colon cancer cells suspension (LoVo cells 0 1ml,1×10 7/L) into caecum wall.
     方法 选用人结肠癌细胞 (Lo Vo细胞 )悬液 (1× 10 7/L) ,OT针注入雌性Balb/C裸鼠盲肠浆膜下 (0 1mL) ,建立人结肠癌细胞裸鼠原位种植模型。
短句来源
     Establishment of prostate cancer model by orthotopic injection of human prostate cancer cell line Du145
     裸鼠前列腺原位肿瘤模型的建立
短句来源
     3. Surgical specimens/tumor cell suspensions were transplanted/injected into the various tissues of BALB/c nude mice (subcutis, perinephrium, COl (cellular orthotopic injection into renal capsule), SOI (surgical orthotopic implantation into renal capsule)).
     2.以1.0mg/ml、20μl/孔对Transwell铺胶,固定细胞悬液浓度(5×10~5/ml),于实验第5天消化回收细胞较为理想。 3.裸小鼠总成瘤率为26.8%(22/82),转移率为2.4%(2/82)。
短句来源
     Human prostatic cancer cells were transfected with the mutated c-erb B2/neu oncogene. The orthotopic injection of the transfected clone N35 to the dorsal prostate of athymic mice resulted in widespread dissemination to various sites. Several studies demonstrated stable integration of pSVneu-T and pSV2neo to the chromosome DNA of human cell.
     用突变的c-erbB2/neu癌基因转染人类PC3细胞系,使转化克隆N35具有癌转移能力,在接种到裸鼠后能向肺、骨髓等远处转移.各项实验指标证实,外源性的neu基因已整合至人类细胞的染色质DNA中,并获得基因扩增和高表达.结果提示neu癌基因与肿瘤的发展和转移能力的形成有密切的关系.
短句来源
更多       
  相似匹配句对
     Split injection;
     分流进样,分流比1∶20。
短句来源
     Sandostatin Injection
     善得定注射液
短句来源
     Orthotopic liver transplantation
     原位肝移植治疗终末期肝硬化
短句来源
     AIM: To establish a prostate cancer orthotopic injection model in nude mice and to discuss its value of application.
     目的:建立一种裸鼠前列腺癌原位模型.
短句来源
     Establishment of prostate cancer model by orthotopic injection of human prostate cancer cell line Du145
     裸鼠前列腺原位肿瘤模型的建立
短句来源
查询“orthotopic injection”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  orthotopic injection
In contrast, 'orthotopic' injection procedures will often enhance the tumorigenic and/or metastatic ability of tumor cell populations.
      
Tumor take and metastasis after orthotopic injection of the three cell lines into mice was monitored.
      
Here we describe the establishment of 468LN cells, a variant of the MDA-MB-468 human breast adenocarcinoma cell line, which produces extensive lymph node metastasis following orthotopic injection of nude mice.
      
In vivo models utilizing orthotopic injection of tumor cells into nude mice have proven valuable for the study of metastasis.
      
Subcutaneous (ectopic) or intra-adrenal (orthotopic) injection of the neuroblastoma cell lines SK-N-SH or IMR-32 has generated a number of derivative tumor cell lines.
      
更多          


Human prostatic cancer cells were transfected with the mutated c-erb B2/neu oncogene. The orthotopic injection of the transfected clone N35 to the dorsal prostate of athymic mice resulted in widespread dissemination to various sites. Several studies demonstrated stable integration of pSVneu-T and pSV2neo to the chromosome DNA of human cell. Clone N35 was found to have amplification and overexpression of neu. The results suggested the possible roles for the neu oncogene in human prostate cancer progression...

Human prostatic cancer cells were transfected with the mutated c-erb B2/neu oncogene. The orthotopic injection of the transfected clone N35 to the dorsal prostate of athymic mice resulted in widespread dissemination to various sites. Several studies demonstrated stable integration of pSVneu-T and pSV2neo to the chromosome DNA of human cell. Clone N35 was found to have amplification and overexpression of neu. The results suggested the possible roles for the neu oncogene in human prostate cancer progression and metastasis.

用突变的c-erbB2/neu癌基因转染人类PC3细胞系,使转化克隆N35具有癌转移能力,在接种到裸鼠后能向肺、骨髓等远处转移.各项实验指标证实,外源性的neu基因已整合至人类细胞的染色质DNA中,并获得基因扩增和高表达.结果提示neu癌基因与肿瘤的发展和转移能力的形成有密切的关系.

Objective To evaluate the impact of laparoscopic colorectal surgery on the port-site and viscera metastasis of colon cancer cells in nude mice .Methods Patient-like metastatic model was established in female Balb/C mice (n=92) via orthotopic injection of human colon cancer cells suspension (LoVo cells 0 1ml,1×10 7/L) into caecum wall.Two weeks later, the nude mice were randomly divided into three groups:a CO 2 pneumoperitoneum group(n=31),a laparotomy group (n=31),an unoperated group(n=30) .Ten...

Objective To evaluate the impact of laparoscopic colorectal surgery on the port-site and viscera metastasis of colon cancer cells in nude mice .Methods Patient-like metastatic model was established in female Balb/C mice (n=92) via orthotopic injection of human colon cancer cells suspension (LoVo cells 0 1ml,1×10 7/L) into caecum wall.Two weeks later, the nude mice were randomly divided into three groups:a CO 2 pneumoperitoneum group(n=31),a laparotomy group (n=31),an unoperated group(n=30) .Ten weeks later sacrificed the nude mice, investigated the implantation and metastasis of tumor cells,and the rate of port-site and viscera metastasis in nude mice with colon tumors was recorded and compared by χ 2 test among the three groups.Results (1)Colon tumor formation occurred in 23/31 mice of the CO 2 pneumoperitoneum group , in 22/31 mice of the laparotomy group, in 21/30 mice of the unoperated group,no significant difference existed.(2)In nude mice with colon tumors ,there was no significant difference between the rate of port-site metastasis in the CO 2 pneumoperitoneum group(2/23) and that in the laparotomy group(4/22),and there was no significant difference when the rates of viscera metastasis were compared among CO 2 pneumoperitoneum group(12/23),laparotomy group(13/22) and unoperated group(10/21). Conclusion The CO 2 pneumoperitoneum does not significantly stimulate the metastasis of colon cancer cells to port-site and viscera in nude mice,laparoscopic surgery in colorectal cancer is safe and feasible.

目的 研究腹腔镜结直肠癌手术对肿瘤切口种植及脏器转移的影响。方法 选用人结肠癌细胞 (Lo Vo细胞 )悬液 (1× 10 7/L) ,OT针注入雌性Balb/C裸鼠盲肠浆膜下 (0 1mL) ,建立人结肠癌细胞裸鼠原位种植模型。 2周后 ,实验裸鼠随机分为 3组 :CO2 人工气腹术组 (31只 )、剖腹术组 (31只 )、和未行手术组 (30只 )。 10周后 ,3组裸鼠均脱颈法处死 ,探查肿瘤细胞原位种植及致瘤鼠肿瘤细胞切口种植及各脏器转移情况。结果  (1) 3组裸鼠的致瘤率为 :CO2 人工气腹组 2 3/ 31例 ,开腹术组 2 2 / 31例 ,未手术组 2 1/ 30例 ,差异无显著意义。 (2 )CO2 人工气腹术组的 2 3只致瘤鼠中 ,有 2只发生切口种植 ,12只发生脏器转移 ;开腹术组的 2 2只致瘤鼠中 ,有 4只发生切口种植 ,13只发生脏器转移 ;未手术组 2 1只致瘤鼠中 ,有 10只发生脏器转移 ,致瘤裸鼠的切口种植及脏器转移率差异无显著意义。结论 CO2 人工气腹没有促进人结肠癌细胞裸鼠原位种植模型切口种植及脏器转移的发生 ,腹腔镜结直肠癌手术具有一定的安全性与可行性。

Objective To investigate tumor metastasis by orthotopic injection of prostate tumor cells PC 98106.Methods For 8 nude mice,lower abdominal incision was made.The bladder and prostate were exposed,the PC 98106 cell suspension 0.2 0.4?ml was injected under the capsule of posterior lobe of prostate,then the vital signs of the nude mouse were observed.After killing the mouse,the tissues of prostate,bladder,lymphatic node,lung,spleen and liver were taken,fixed in 10% neutral buffered formalin,embedded in...

Objective To investigate tumor metastasis by orthotopic injection of prostate tumor cells PC 98106.Methods For 8 nude mice,lower abdominal incision was made.The bladder and prostate were exposed,the PC 98106 cell suspension 0.2 0.4?ml was injected under the capsule of posterior lobe of prostate,then the vital signs of the nude mouse were observed.After killing the mouse,the tissues of prostate,bladder,lymphatic node,lung,spleen and liver were taken,fixed in 10% neutral buffered formalin,embedded in paraffin and observed microscopically.The metastasis to the skeleton was observed by X ray.The micromorphology of prostate tumor was also examined.Results Five models were successfully established.About 10 days later,there were small nodes in prostate,and about 60 days later,cachexia occurred in the nude mice.After dissection,it was found there was invasion to the bladder and metastasis to pelvic lymphatic node and also micro metastasis to liver.But no metastasis to skeleton was observed.Conclusion Orthotopic transplantation model prognosis of prostate tumor is similar to that of clinical prostate tumor and may be very useful for the research of metastasis.

目的 应用前列腺梭形细胞瘤细胞系PC 981 0 6建立人前列腺肿瘤原位移植模型 ,观察肿瘤局部浸润和远处转移情况。方法  8只裸鼠取下腹部切口 ,显露膀胱和前列腺 ,将PC 981 0 6细胞悬液 0 .2~ 0 .4ml注射于前列腺后叶包膜下。观察裸鼠生命体征的变化 ,取原位肿瘤、膀胱、盆腔淋巴结、肺脏、肝脏、脾脏标本福马林液固定 48h ,苏木素 伊红染色后显微镜下观察。原位移植瘤电镜观察 ,X线照射显示骨骼转移情况。结果  5只模型建立成功 ,1 0d左右 ,可触及前列腺部位有小结节。 60d左右 ,裸鼠出现明显恶液质。解剖后发现盆腔淋巴结肿大 ,显微镜观察膀胱有浸润 ,肝脏有微转移灶。X线未见骨骼转移。结论 前列腺肿瘤原位移植模型的转归接近于临床 ,是肿瘤转移研究的较好模型

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关orthotopic injection的内容
在知识搜索中查有关orthotopic injection的内容
在数字搜索中查有关orthotopic injection的内容
在概念知识元中查有关orthotopic injection的内容
在学术趋势中查有关orthotopic injection的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社