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   oral mucosas 的翻译结果: 查询用时:0.013秒
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oral mucosas
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  口腔粘膜
     When most serious mucositis, the patients' oral mucosas were checked, 32 patients with fungal infection were treated with fluconazole (fluconazole 100 mg, po , qd×5 d or 150 mg,iv,gtt×3 d).
     年龄 52a±s 4 1a( 11~ 76a) ,在病人的口腔粘膜反应最严重的时候 ,做口腔粘膜真菌学检查 ,32例有真菌感染的病人 ,用氟康唑胶囊 10 0mg ,po ,qd× 5d或氟康唑注射液 150mg ,iv ,gtt× 3d治疗。
短句来源
     P53 protein expression was studied with immunohistochemically in 15normal oral mucosas, 45 precancerous lesions and 21 invasive squamous cell carcinomas.
     用免疫组化技术检测了15例正常口腔粘膜、45例癌前病变和21例浸润性鳞癌标本的P53蛋白的表达。
短句来源
     The positive rate of P(53) protein was significantly different among normal oral mucosas,precancerous lesions and invasive squamous cell carcinomas (P<0. 05).
     癌前病变和浸润性鳞癌P53的阳性表达率分别是22.2%和47.6%,癌前病变与正常口腔粘膜之间和浸润性鳞癌与癌前病变之间差异均有显著性(P<0.05)。
短句来源
     Telomerase activity was negative in 4 papillary tumors,4 mixed tumors,2 ameloblastomas,5 normal oral mucosas.
     4例乳头状瘤、4例混合瘤、2例造釉细胞瘤、5例正常口腔粘膜端粒酶表达均为阴性。
短句来源
     Thirty two oral and maxillofacial cancers and 32 adjacent peritumoral tissues,4 papillary tumors,4 mixed tumors,2 ameloblastomas,5 normal oral mucosas,were examined for telomerase activity by silver staining TRAP assay based on PCR.
     [方法]用银染 TRAP法检测32例口腔颌面部癌组织及其相应的32例癌旁组织、4例混合瘤、4例乳头状瘤、2例造釉细胞瘤、5例正常口腔粘膜的端粒酶活性。
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  “oral mucosas”译为未确定词的双语例句
     Method Immunohistochemical S-P method was used in this study to dete ct the expressions of p27 and p16 protein in 37 OSCCs, 30 pericancerous mucosas and 10 normal oral mucosas . Result The reduced expressions of p27 and p16 were related to the d evelopment and extent of malignancy of OSCCs.
     方法 采用 p2 7与 p16单克隆抗体 ,用免疫组化S -P法对 3 7例口腔鳞癌组织、3 0例癌旁组织、10例正常口腔黏膜 p2 7与p16的表达进行检测 ,结果 p2 7与 p16表达减少与口腔鳞癌的发生和恶性程度有关。
短句来源
     Methods Immunohistochemical S-P method was applied to examine the expressions of P16 in 56 oral squamous cell carcinomas, 30 pericancerous mucosas and 10 normal oral mucosas and the image analysis technology was applied to measure the intensity of staining quantitatively. Results P16 expression quantity in oral squamous cell carcinomas was lower than that in pericancerous mucosas and normal oral mucosas apparently (P<0.05).
     方法 采用免疫组化S -P法,对5 6例口腔鳞癌组织、30例癌旁组织及10例正常口腔黏膜中P16蛋白的表达进行检测,应用全自动图像分析仪对染色结果进行定量测定。
短句来源
     Objective: To explore the role of cyclin G2 in the occurrence and development of oral squamous cell carcinoma(OSCC) by determining the expression and distribution of cyclin G2.Methods: The expression of cyclin G2 was determined by immunohistochemical S-P method in 39 OSCC tissues of and 20 normal oral mucosas.
     目的:探讨细胞周期蛋白G2(cyc lin G2)表达在口腔鳞癌发生和发展中的意义。
短句来源
  相似匹配句对
     TELOMERASE ACTIVITY IN NORMAL ORAL MUCOSAS
     正常口腔粘膜上皮细胞端粒酶活性的观察
短句来源
     Objective To detect the telomerase activity in normal oral mucosas.
     目的 检测正常口腔粘膜上皮细胞端粒酶活性。
短句来源
     Oral Hygiene
     口腔卫生
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     Oral English
     (英语口语)
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  oral mucosas
Enzyme activities involved in collagen and proteoglycan degradations in oral mucosas of beige (Chediak-Higashi syndrome) mice
      


P53 protein expression was studied with immunohistochemically in 15normal oral mucosas, 45 precancerous lesions and 21 invasive squamous cell carcinomas.In normal musosa, the immunoreactivity of P(53) was negative while in precancerous lesions and squamous cell carcinomas,P(53) positively expressed in the nuclei and kept increased with malignancy. The positive rate of P(53) protein was significantly different among normal oral mucosas,precancerous lesions and invasive squamous cell carcinomas (P<0....

P53 protein expression was studied with immunohistochemically in 15normal oral mucosas, 45 precancerous lesions and 21 invasive squamous cell carcinomas.In normal musosa, the immunoreactivity of P(53) was negative while in precancerous lesions and squamous cell carcinomas,P(53) positively expressed in the nuclei and kept increased with malignancy. The positive rate of P(53) protein was significantly different among normal oral mucosas,precancerous lesions and invasive squamous cell carcinomas (P<0. 05). This demonstrated that the mutation of P(53) suppressor gene occcurs in the initiation of carcinogenesis of oral mucosa and prior to the malignant phenotype of cells.A close correlation may exist in the formation of oral cancer and P53 gene aberration. The overexpression of P(53) protein may be a biomarker in the developement of oral cancer and valuable in cancer diagnosis.

用免疫组化技术检测了15例正常口腔粘膜、45例癌前病变和21例浸润性鳞癌标本的P53蛋白的表达。结果表明,正常口腔粘膜中无P53表达;癌前病变和浸润性鳞癌P53的阳性表达率分别是22.2%和47.6%,癌前病变与正常口腔粘膜之间和浸润性鳞癌与癌前病变之间差异均有显著性(P<0.05)。提示P53基因突变发生在口腔粘膜癌变的启动阶段,即细胞呈明显恶性表现型之前。P53基因突变及P53蛋白的过度表达可能与口腔癌的发生密切相关,P53可作为口腔鳞癌发生发展过程中的生物学指标及口腔鳞癌早期诊断的参考依据。

AIM: To study the relation of acute radiation induced oral mucositis to fungal infection and evaluate the effect of fluconazole in the treatment of patients with fungal infection. METHODS: Seventy one patients (M 42, F 29; 52 a± s 41 a,11-76 a) with large area of oral mucosas irradiated were into this study. When most serious mucositis, the patients' oral mucosas were checked, 32 patients with fungal infection were treated with fluconazole (fluconazole 100 mg, po , qd×5 d or 150 mg,iv,gtt×3...

AIM: To study the relation of acute radiation induced oral mucositis to fungal infection and evaluate the effect of fluconazole in the treatment of patients with fungal infection. METHODS: Seventy one patients (M 42, F 29; 52 a± s 41 a,11-76 a) with large area of oral mucosas irradiated were into this study. When most serious mucositis, the patients' oral mucosas were checked, 32 patients with fungal infection were treated with fluconazole (fluconazole 100 mg, po , qd×5 d or 150 mg,iv,gtt×3 d). RESULTS: The rate of fungal infection was 45%, the most of patients were infected by candida albicans. Degrees of mucositis between the patients with fungal infection to the patients without fungal infection were significantly different ( P <0.05). The patients with fungal infection were treated with fluconazole. Degree of mucositis between the pretreated patients and post treated patients were significantly different ( P <0.05). CONCLUSION: The serious acute radiation induced oral mucositis has significantly related with fungal infection. The patients with fungus infection treated with antifungal agents (fluconazole) can significantly relieve the reaction of acute radiation induced oral mucositis.

目的 :研究头颈部肿瘤放射治疗中急性放射性口腔粘膜反应与真菌感染的关系及氟康唑治疗的有效性。方法 :71例口腔粘膜受到大面积照射的肿瘤病人 :男性 4 2例 ,女性 2 9例 ;年龄 52a±s 4 1a( 11~ 76a) ,在病人的口腔粘膜反应最严重的时候 ,做口腔粘膜真菌学检查 ,32例有真菌感染的病人 ,用氟康唑胶囊 10 0mg ,po ,qd× 5d或氟康唑注射液 150mg ,iv ,gtt× 3d治疗。结果 :真菌的检出率为 4 5% ,以白念珠菌感染为主。有真菌感染和无真菌感染的 2组病人 ,在急性放射性粘膜反应上差异有显著意义 (P <0 .0 5) ;有真菌感染的病人用氟康唑治疗 ,治疗前后的粘膜反应差异有显著意义 (P<0 .0 5)。结论 :严重的急性放射性粘膜反应与真菌感染有密切的关系 ;有真菌感染的放射性口腔粘膜反应用氟康唑治疗可以明显减轻放射性粘膜反应

To investigate the telomerase activity in human oral and maxillofacial cancer and corresponding adjacent tissues,to explore the possibility of telomerase as tumor marker and its clinicopathological significance.Thirty two oral and maxillofacial cancers and 32 adjacent peritumoral tissues,4 papillary tumors,4 mixed tumors,2 ameloblastomas,5 normal oral mucosas,were examined for telomerase activity by silver staining TRAP assay based on PCR.Thirty of 32 oral and maxillofacial cancers and 2 of 32...

To investigate the telomerase activity in human oral and maxillofacial cancer and corresponding adjacent tissues,to explore the possibility of telomerase as tumor marker and its clinicopathological significance.Thirty two oral and maxillofacial cancers and 32 adjacent peritumoral tissues,4 papillary tumors,4 mixed tumors,2 ameloblastomas,5 normal oral mucosas,were examined for telomerase activity by silver staining TRAP assay based on PCR.Thirty of 32 oral and maxillofacial cancers and 2 of 32 adjacent peritumoral tissue specimens were positive for telomerase activity with a positive rate of 93.7% and 6.3%,respectively.Telomerase activity was negative in 4 papillary tumors,4 mixed tumors,2 ameloblastomas,5 normal oral mucosas.There was no correlation between the clinical stage of oral and maxillofacial cancer and their expression of telomerase activity(P>0.05).[Conclusion]Positive telomerase activity occurs in the majority of oral and maxillofacial cancer examined. It can be used as a tumor marker in the diagnosis oral and maxillofacial cancer.The telomerase activation of the peritumoral tissue shows fewer tumor cells and should be followed up to be proved.

[目的]研究口腔颌面部癌组织及相应癌旁组织中的端粒酶活性 ,探讨其作为口腔颌面部癌肿瘤标志物的可行性及其临床意义。[方法]用银染 TRAP法检测32例口腔颌面部癌组织及其相应的32例癌旁组织、4例混合瘤、4例乳头状瘤、2例造釉细胞瘤、5例正常口腔粘膜的端粒酶活性。[结果]32例口腔颌面部癌组织中 ,有30例端粒酶活性表达阳性 ,其阳性率为93.7%。32例癌旁组织中 ,有2例端粒酶表达阳性 ,其阳性率为6.3%。4例乳头状瘤、4例混合瘤、2例造釉细胞瘤、5例正常口腔粘膜端粒酶表达均为阴性。口腔颌面部癌组织端粒酶活性表达与该肿瘤的临床病理特征无明显相关性(P>0.05)。[结论]口腔颌面部癌组织中普遍存在端粒酶活性表达 ,而口腔良性肿瘤和正常口腔组织中端粒酶活性较少表达 ,端粒酶可作为诊断口腔颌面部癌的肿瘤标志物。癌旁组织端粒酶活化提示有少量肿瘤细胞 ,应随访以证实。

 
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