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mandibular bone defects
相关语句
  下颌骨缺损
     Reconstruction of Bilateral Mandibular Bone Defects——Report of 12 Cases
     两侧下颌骨缺损的修复(附12例报告)
     Conclusions Reverse engineering combining with rapid prototyping could accomplish the design and manufacture of implant for the restoration of mandibular bone defects.
     结论 反求结合快速原型能够完成下颌骨缺损的修复体的设计和制造 ,提高了手术精度 ,节省了手术时间 ,在颌骨缺损的个体化和定制化修复中有独特的优势
短句来源
     Conclusion Reverse engineering combining with rapid prototyping could accomplish the design and manufacture of implant for the restoration of mandibular bone defects.
     结论:反求结合快速成型能够完成下颌骨缺损的修复体的设计和预制,提高了手术精度,节省了手术时间,在颌骨缺损的个体化和定制化修复中有独特的优势。
短句来源
     Experiment of fabricating titanium implant individually by using the techniques of SLS way to reconstruct mandibular bone defects
     用SLS法定制修复下颌骨缺损的钛植入体的实验研究
短句来源
     Conclusion:SLS way combining with titanium casting can be used to reconstruct human mandibular bone defects individually.
     结论:应用SLS法定制修复下颌骨缺损的植入体精度高,耗时短,是一种很有前景的个性化修复下颌骨缺损的方法。
短句来源
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  “mandibular bone defects”译为未确定词的双语例句
     An Experimental Study on the Effects of Bone Formation and Repair of Rats Mandibular Bone Defects Using ADSCs Transferred with BMP-2 Gene Combined with CTCP
     BMP-2基因转染ADSCs复合CTCP成骨及修复颌骨缺损的实验研究
短句来源
     Studies on the Application of Poly(Propylene Fumarate)-based Composite Materials in the Repairing of Mandibular Bone Defects
     丙二醇/反丁烯二酰氯缩聚物复合材料在颌骨缺损修复中的应用基础研究
短句来源
     Repair of dog mandibular bone defects using rhBMP carrier system compounded with BMCs
     rhBMP载体系统复合骨髓基质干细胞修复犬颌骨缺损
短句来源
     In this study, Reverse Engineering and Rapid Prototyping techniques were used in the reconstruction of mandibular bone defects, chin augmentation as well as hemifacial atrophy cases.
     将反求与快速成型技术运用于颌面畸形与骨缺损的整复领域,能够达到理想恢复面部形态与功能的目的,特别是在颌骨替代物的形状匹配中具有独特的优势,符合当前修复体个体化设计的趋势,具有广泛的应用前景。
短句来源
     1 Restoration of mandibular bone defects based on reverse engineering and rapid prototyping.
     1反求与快速成型技术在下领骨缺损整复中的应用研究
短句来源
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  相似匹配句对
     ANALYSIR OF CORRELATIVE FACTORS OF MANDIBULAR BONE
     下颌骨的相关因素分析
短句来源
     The Linear Regressive Eguation of Mandibular Bone
     下颔骨的线性回归分析
短句来源
     RIGID FIXATION FOR THE BONE GRAFT OF MANDIBULAR DEFECTS
     下颌骨缺损游离植骨的坚固固定
     Mechanotransduction in Bone
     力学信号在骨骼中的转导
短句来源
     The Dog and the Bone
     狗与骨头(英文)
短句来源
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  mandibular bone defects
A mixture of tricalcium phosphate (TCP) and ε-caprolactone-lactide copolymer P(ε -CL/DL-LA) was prepared and implanted in critical size mandibular bone defects in twelve sheep.
      


Objective Element Strontium of different ration was added to Hydroxyalapatite by altering element Ca in order to study the application of rehabilitation of mandibular bone defect through animal experiment. Method 32 rabbits were divided into 4 groups for detailed study. Bone defects with size of 6mm×12mm×4mm were made at the mandibular angles of rabbits and Sr HAP with different proportion (10%, 5%, 0%) was applied to reform the bone defect. One animal group which was randomly...

Objective Element Strontium of different ration was added to Hydroxyalapatite by altering element Ca in order to study the application of rehabilitation of mandibular bone defect through animal experiment. Method 32 rabbits were divided into 4 groups for detailed study. Bone defects with size of 6mm×12mm×4mm were made at the mandibular angles of rabbits and Sr HAP with different proportion (10%, 5%, 0%) was applied to reform the bone defect. One animal group which was randomly selected was killed separately at 2 weeks, 1 month, 3 months, 6 months to evaluate the capacity of bone rehabilitation with methods as anatomy observation, histology analysis and SEM (Scanning Electron Microscope). Results Sr HAP almost hadn't been rejected by host bone, and early after operation the new bone was induced to the porous materials space with the degradation of Sr HAP, and gradualy the undegraded stem cell was transfered to mature osteoplast. The total osteoplastic capacity of Sr hap is higher than that of pure Hydroxyapatite during the whole period, at the same time we also found 5% Sr HAP had a better bone reconstruction capability than 10% Sr HAP. Conclusion Sr HAP has a better biocompatibility and biodegradation than pure HA and has an excellent osteoinductivity. The osteoplastic ability of Sr HAP has no positive relationship with proportion of Strontium increasing in the materials.

目的 用不同比例的元素锶 (Sr)替代羟磷灰石 (HA)中的部分钙元素 ,通过动物实验研究该种复合人工骨在颌骨缺损修复中的应用。方法 将 32只新西兰大白兔 (简称新白 )分为 4组 ,在兔的下颌角造成约 2 m m×12 mm× 4mm的缺损 ,用不同浓度 (10 % ,5 % ,0 % )的含锶 HA块分别予以修复 ,于 2周 ,1月 ,3月 ,6月时随机处死一组进行尸解、组织学、扫描电镜观察以评价其骨修复能力。结果 掺锶羟基磷灰石复合人工骨几乎不引起排斥反应 ,术后早期即随材料的降解 ,新生骨引导进入降解间隙 ,并逐渐诱导未分化细胞转化为成骨细胞 ,随时间延长其成骨量明显较纯羟基磷灰石组为多 ,同时发现 5 %的锶磷灰石烧结体其成骨能力较 10 %者好。结论 掺锶羟基磷灰石较纯羟基磷灰石有更好的组织相容性、骨引导能力及生物降解率 ,并可能具备一定程度的骨诱导能力 ;掺锶羟基磷灰石的骨形成能力与其浓度并不成正相关。

Objective To evaluate the feasibility of designing and fabricating customized titanium bone substitutes to restore mandibular bone defects using reverse engineering (RE) and rapid prototyping (RP) techniques. Methods Titanium tray for mandibular defects were designed and fabricated through multi step procedures of reverse engineering and rapid prototyping, then in operation it was filled with cancellous bone and fixed. Results The bone substitutes fabricated by this method had...

Objective To evaluate the feasibility of designing and fabricating customized titanium bone substitutes to restore mandibular bone defects using reverse engineering (RE) and rapid prototyping (RP) techniques. Methods Titanium tray for mandibular defects were designed and fabricated through multi step procedures of reverse engineering and rapid prototyping, then in operation it was filled with cancellous bone and fixed. Results The bone substitutes fabricated by this method had been successfully put into clinical use for maxillofacial surgery in 2 patients and got a satisfactory result. Conclusions Reverse engineering combining with rapid prototyping could accomplish the design and manufacture of implant for the restoration of mandibular bone defects.

目的 探讨应用反求工程和快速原型技术进行下颌骨缺损修复的设计和植入体制作的可行性。方法 应用反求工程和快速原型技术完成 2例下颌骨缺损的修复体设计和制作 ,并行修复体植入术。结果 经计算机设计和严密制作的修复体术中仅数分钟顺利就位 ,各部件达到设计位置 ,术后患者面部外形与健侧对称 ,咬合关系良好 ,下颌偏斜纠正。结论 反求结合快速原型能够完成下颌骨缺损的修复体的设计和制造 ,提高了手术精度 ,节省了手术时间 ,在颌骨缺损的个体化和定制化修复中有独特的优势

Objective: To study the effects of tissue engineered bone in the repair of mandibular defect.Methods:The experiments were conducted in 12 dogs.Bone marrow stromal stem cells(BMSCs) of dog were cultured in DMEM containing 100 ml/L fetal bovine serum and induced to differentiate towards osteoblasts.Then the cells were seeded onto absorbable polylactic acid(PLA) compounded with rhBMP-2(0.16 mg for each implant), the composite was implanted into the oval-shaped mandibular bone defect...

Objective: To study the effects of tissue engineered bone in the repair of mandibular defect.Methods:The experiments were conducted in 12 dogs.Bone marrow stromal stem cells(BMSCs) of dog were cultured in DMEM containing 100 ml/L fetal bovine serum and induced to differentiate towards osteoblasts.Then the cells were seeded onto absorbable polylactic acid(PLA) compounded with rhBMP-2(0.16 mg for each implant), the composite was implanted into the oval-shaped mandibular bone defect in the size of 30 mm×12 mm on one side,another side was used as blank control.The dogs were divided into 4 grups with 3 in each group.PLA/rhBMP/BMSCs,PLA/rhBMP,PLA/BMSCs and PLA were used as the implants in group A,B,C and D respectively. 2, 4 and 8 weeks after implantation,the effectiveness of bone formation was evaluated by means of gross observation,histological and scanning electronic microscope ( SEM) examination. Results: In group A new bone formation in the implanted defects was observed 4 weeks after operation, the defects were replaced by muture bone tissue 8 weeks after operation. In group B a little new bone was found in the implanted area 4 weeks after operation and fibrous bone was observed 8 weeks after operation. In group C chondral ossification was found and in group D fibrous tissue was found in the bone defects 8 weeks after operation.Conclusion:PLA/rhBMP/BMSCs may be feasible in the repair of bone defect.

目的:利用组织工程骨诱导颌骨再生,修复颌骨缺损的效能评价。方法:取犬骨髓基质干细胞(BMSC)于含 100ml/L胎牛血清的DMEM培养液中培养,并向成骨细胞诱导。将细胞与可吸收性聚乳酸 (PLA)、重组人骨形成蛋白(rhBMP)复合植入右侧下颌骨 30×12mm椭圆形缺损区,左侧骨缺损区不植骨,作为空白对照,收 12只狗分为 4组,每组 3只,A组试验侧植入PLA/rhBMP/BMSCs,B组植入PLA/rhBMP,C组植入PLA/BM SCs,D组植入PLA。2、4、8周时行X线检查,取材组织行组织病理及扫描电镜检查,观察成骨情况。结果:A组实验侧 4周时,有小片状类骨质出现, 8周时新生骨形成大片状结构,PLA大部分降解,缺损由骨组织修复,成骨量明显大于B组或C组及D组,而空白对照侧仅为纤维组织修复。结论:聚乳酸、重组人骨形成蛋白、骨髓基质干细胞构建的组织工程骨,可诱导颌骨再生,能修复骨缺损,作为骨缺损修复材料,应用前景良好。

 
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