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   联合细胞毒诱导分化 的翻译结果: 查询用时:0.183秒
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联合细胞毒诱导分化
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  differentiation inducers in combination with cytotoxic agents
     Effects of differentiation inducers in combination with cytotoxic agents on human gastric carcinoma cell line SGC 7901
     联合细胞毒诱导分化对胃癌SGC-7901细胞株作用的研究
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  “联合细胞毒诱导分化”译为未确定词的双语例句
     Conclusion: The combined use of the three agents can significantly inhibit proliferation, induce differentiation and promote apoptosis in the gastric carcinoma cells.
     结论:3种药物联合使用时可对胃癌细胞产生显著的抑制增殖、诱导分化和促凋谢作用。 联合细胞毒诱导分化对胃癌细胞有明显的抗肿瘤作用
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  相似匹配句对
     Cytochalasin B
     细胞B
短句来源
     Effects of differentiation inducers in combination with cytotoxic agents on human gastric carcinoma cell line SGC 7901
     联合细胞诱导分化对胃癌SGC-7901细胞株作用的研究
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     Experimental Study of Combination Therapy against Human Glioma Xenograft by Differentiation-Inducing Agent and Cytotoxic Chemotherapeutic Drug
     诱导分化剂与细胞化疗药联合治疗可移植性人脑胶质瘤的实验研究
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     INDUCED-DIFFERENTIATION AND CYTOTOXICITY OF ISOVERBASCOSIDE ON HL-60 CELLS
     Isoverbascoside对HL-60细胞诱导分化细胞作用
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     Studies on the differentiation of HL-60 cells induced by cinnamic acid and vitamin C
     桂皮酸联合维生素C对HL-60的细胞诱导分化
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Objective: To investigate the effects of differentiation inducers in combination with cytotoxic agents on human gastric carcinoma cell line and explore a new approach of treatment to the cancer. Methods: The effects of ATRA in combination with α IFN and 5 Fu on human gastric carcinoma cell line SGC 7901 were observed in vitro. The gastric carcinoma cell line was exposed to the three agents in single, two agent combining or three agent combining manner respectively. The morphological and functional...

Objective: To investigate the effects of differentiation inducers in combination with cytotoxic agents on human gastric carcinoma cell line and explore a new approach of treatment to the cancer. Methods: The effects of ATRA in combination with α IFN and 5 Fu on human gastric carcinoma cell line SGC 7901 were observed in vitro. The gastric carcinoma cell line was exposed to the three agents in single, two agent combining or three agent combining manner respectively. The morphological and functional changes of the cell line were observed with MTT, flow cytometry, image analysis and CEA. Results: ①The cytostatic rates of the cell line were gradually increased while plating efficiency decreased after the treatment in three manners. The cells at G 0/G 1 phase were relatively increased and synthesis of DNA inhibited. ②The malignant phenotype of the cell line gradually disappeared while characteristics of mature cell were progressively increased. ③Obvious cell apoptosis and plenty of apoptotic bodies were seen after treatment. Conclusion: The combined use of the three agents can significantly inhibit proliferation, induce differentiation and promote apoptosis in the gastric carcinoma cells.

目的:探讨诱导分化剂联合细胞毒药物对胃癌细胞的作用效能,寻找治疗胃癌的新途径。方法:应用全反式维甲酸(ATRA)、α-干扰素(α-IFN)和5-Fu,分别以单用、两两双用和联用对胃癌细胞系SGC-7901细胞作用,用MTT法、流式细胞术、图像分析和CEA测定等方法观察细胞的形态和功能变化。结果:①随着单用、双用和联用对胃癌细胞的抑制率逐渐升高,平皿克隆形成率逐渐下降,细胞周期示G0/G1期细胞相对积聚,DNA合成受抑制。②癌细胞恶性表型逐渐消失,成熟细胞特征逐渐增多,培养液CEA滴度逐渐下降。③药物作用后细胞凋谢现象明显,可见大量凋谢小体。结论:3种药物联合使用时可对胃癌细胞产生显著的抑制增殖、诱导分化和促凋谢作用。联合细胞毒诱导分化对胃癌细胞有明显的抗肿瘤作用

 
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