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the rabbit method
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  家兔法
     Depending on the results,the judgement of LAL assay to replace rabbit method for pyrogen test of meningococcal polysaccharide vaccine group A was built up ,and writer suggest:if the endotoxin concentration was <100IU/μg,the product should be considered to pass pyrogen test; if the endotoxin concentration was≥ l00IU/μg,the rabbit method should be used to arbitrate finally.
     根据实验结果,可制订用凝胶法替代家兔法进行A群流脑多糖菌苗的热原质试验的判定标准。 作者建议:内毒素含量<100IU/μg多糖者,热原质试验判为合格,≥100IU/μg多糖者,用家兔法予以仲裁。
短句来源
     Aim: To test bzacterial endotosin in ofloxarin injectio with TAL TAL reagent. Method: The bacterial endotoxin ofloxacin injection according to Pharmacopoeia of the People's Republic of China 2000. Result: The bacterial endotoxin in ofloxacin injection could be effectively determined with the marker value 0. 25KU/ml as sensitivity. Conclution: The rabbit method can be replaced by TAL reagent method to determine the pyrogen in ofloxacin injection.
     目的:有鲎试剂检测氧氟沙星注射液的内毒素 方法:参照中国药典1995年版二部收载的细菌内毒素检查方法进行检测 结果:氧氟沙星注射液中细菌内毒素用标示值灵敏度为0.25EU·ml~1检测有效 结论:鲎试剂法可代替氧氟沙星注射液热原检查项目中的家兔法
短句来源
     This experiment analyzes and resolves the interference affect of cefazolin sodium for injection to TAL by adopting the maximum effective dilution method. It is considered that detection method of bacterium endotoxin can be applied for detecting the endotoxin in the sample and the result is the same comparing with the rabbit method.
     本试验采用最大有效稀释法,分析并解决了注射用头孢唑啉钠对鲎试剂的干扰作用,认为细菌内毒素检测法可用于该样品中内毒素的检测,且与家兔法比较结果完全一致。
短句来源
     Conclusion The bacterial endotoxins test can replacement the rabbit method for pyrogen test.
     结论 细菌内毒素检查法可代替家兔法进行平衡液热原 检查。
短句来源
     Conclusion It is available for the bacterial eodotoxin test by diluting the Potassium Dehydroandrograpolide Succinate Injection to 0.5 mg/mL in tachypleus amebocyte lysate method and it can substitute for the Rabbit Method in quality control.
     结论穿琥宁注射液稀释至0.5 mg/mL时,对细菌内毒素检查无干扰,用鲎试剂法代替家兔法控制穿琥宁注射液的热原是可行的。
短句来源
  “the rabbit method”译为未确定词的双语例句
     According to the rabbit method recommended by WHO, we have improved the detailed experimental method of Eckstein.
     根据WHO推荐的兔法,我们对Eckstein提供的具体实验方法作了改进。
短句来源
     Conclusion:After dilution of the soclium citrate injection for transfusion in accordance with the sensitivity of TAL and proved feasibee by booster inhibition test, the pyrogen can be detected with the method of TAL but must be justfied by the rabbit method when pyrogen is positive
     结论 枸橼酸钠注射液可根据鲎试剂灵敏度进行稀释后通过加强抑制试验验证可行后 ,用鲎法做热原的初筛试验 ,若出现阳性时再选用兔法仲裁
短句来源
     Conclusion:It is available for test of the bacterial endotoxin by diluting the oxaliplatin for injection to 2 mg/mL in tachypleus amebocyte lysate method and it can substitute for the Rabbit Method in quality control.
     结论:本品1mL含奥沙利铂2mg的供试品及其稀释液对细菌内毒素检查无干扰。 可用鲎试验法代替家兔热原检查法控制奥沙利铂注射液的热原。
短句来源
     Conclusion:Bacterial endotoxin test can be used in place of the rabbit method for quality monitoring of fosfomycin sodium for injection.
     结论:细菌内毒素检查法代替家兔热原检查法用于注射用磷霉素钠的质量监控是可行的。
短句来源
  相似匹配句对
     The Rabbit of Seville
     《塞维利亚野兔》(英文)
短句来源
     The Rainbow Rabbit
     彩虹兔
短句来源
     Rabbit, Rat and Cat
     唐锡阳绿色沉思与百家评点 兔子、老鼠和猫
短句来源
     Diagnosis of Rabbit Pasteurellosis
     兔巴氏杆菌病的诊断
短句来源
     BLUP Method in Rabbit Breeding
     BLUP法在种兔选择上的应用
短句来源
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In order to ensure safety in the application of vaginal contraceptives, it is necessory to assess exactly the tolerance of local irritation of vaginal contraceptives. According to the rabbit method recommended by WHO, we have improved the detailed experimental method of Eckstein. The improved method is simpler to manipulate and the experimental instruments are easierto be produced than the original one. In addition, it can correctly show drug irritation. Havinganalysed our experimental results,...

In order to ensure safety in the application of vaginal contraceptives, it is necessory to assess exactly the tolerance of local irritation of vaginal contraceptives. According to the rabbit method recommended by WHO, we have improved the detailed experimental method of Eckstein. The improved method is simpler to manipulate and the experimental instruments are easierto be produced than the original one. In addition, it can correctly show drug irritation. Havinganalysed our experimental results, we suggest that histological examination of the middle portionof the vagina under microscope should be desirable. The calculation of the inflammatory score ofthe two inflammatory indices, that is. epithalaxia and leukocytic infiltration, will save much more time, labour and reagent, and what is more, it is easy to differentiate one vaginal contracep-tive irritation from another. Our findings indicate that vaginal spermicides in our country haveno systemic toxicity to rabbits in a short period of time.

为了保证用药的安全性,需对阴道避孕药局部刺激的耐受性作出评价。根据WHO推荐的兔法,我们对Eckstein提供的具体实验方法作了改进。改进后,操作更简便,器械更宜制作,且能准确的反映药品对阴道的刺激性。实验结果分析之后,我们建议只用阴道中段镜检,仅用上皮脱落和炎性细胞浸润两个单项炎症指标计算炎症分值,可省工、节时,减少试剂消耗,更有利于把各药品的刺激性区分开。实验结果表明,我国应用的外用避孕药膜对家兔没有全身近期毒性作用。

The endotoxin concentration of 212 lots of meningococcal polysaccharide vaccine group A was determined quantitatively by LAL test. The results were compared with rabbit test.The Linear regression relation beween endotoxin concentration and temparature rise of rabbit was established ,the minimus rabbit pyrogen dose was got. The results showd that when endotoxin concentation of praduct is <100IU/μg polysacchoride,rabbit test was pass 100%,there were 94. 3% lots of product in this range; when endotoxin concentration...

The endotoxin concentration of 212 lots of meningococcal polysaccharide vaccine group A was determined quantitatively by LAL test. The results were compared with rabbit test.The Linear regression relation beween endotoxin concentration and temparature rise of rabbit was established ,the minimus rabbit pyrogen dose was got. The results showd that when endotoxin concentation of praduct is <100IU/μg polysacchoride,rabbit test was pass 100%,there were 94. 3% lots of product in this range; when endotoxin concentration of product was≥ 100IU/μg polysacchoride,rabbit test was pass 58.3%,there were 5. 7% lots of product in this range. Depending on the results,the judgement of LAL assay to replace rabbit method for pyrogen test of meningococcal polysaccharide vaccine group A was built up ,and writer suggest:if the endotoxin concentration was <100IU/μg,the product should be considered to pass pyrogen test;if the endotoxin concentration was≥ l00IU/μg,the rabbit method should be used to arbitrate finally.

本文应用鲎试验凝胶法定量测定了212批A群流脑多糖菌苗中内毒素含量,并与家兔热原试验结果进行了比较,通过试验求得内毒素标准品对家兔体温升温变化关系的线性方程和内毒素对家兔最小致热剂量。结果表明,占检定总批数94.3%的制品中内毒素含量<100IU/μg多糖,家兔热原试验合格率为100%,5.7%的制品中内毒素含量≥100IU/μg多糖,家兔热原试验合格率为58.3%。根据实验结果,可制订用凝胶法替代家兔法进行A群流脑多糖菌苗的热原质试验的判定标准。作者建议:内毒素含量<100IU/μg多糖者,热原质试验判为合格,≥100IU/μg多糖者,用家兔法予以仲裁。

Objective:To study a rapid and sensitive method with TAL for bacterial endotoxin detection.Motheds: TAL was used to detect endotoxins in the ten batches of sodium citrate injection for transfusion that had been proved proper by the Rabbit Method.Results: There was not any difference between the method of TAL and the rabbit mothed.Conclusion:After dilution of the soclium citrate injection for transfusion in accordance with the sensitivity of TAL and proved feasibee by booster inhibition test, the pyrogen can...

Objective:To study a rapid and sensitive method with TAL for bacterial endotoxin detection.Motheds: TAL was used to detect endotoxins in the ten batches of sodium citrate injection for transfusion that had been proved proper by the Rabbit Method.Results: There was not any difference between the method of TAL and the rabbit mothed.Conclusion:After dilution of the soclium citrate injection for transfusion in accordance with the sensitivity of TAL and proved feasibee by booster inhibition test, the pyrogen can be detected with the method of TAL but must be justfied by the rabbit method when pyrogen is positive

目的 探讨一种简便、快速、灵敏的检测方法。方法 采用鲎法检测细菌内毒素。结果 取 10批经家兔法热原合格的枸橼酸钠注射液进行比较 ,二者结果吻合。结论 枸橼酸钠注射液可根据鲎试剂灵敏度进行稀释后通过加强抑制试验验证可行后 ,用鲎法做热原的初筛试验 ,若出现阳性时再选用兔法仲裁

 
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