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fulminant hepatitis
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  相似匹配句对
     THE ETIOLOGY OF FULMINANT VIRAL HEPATITIS
     重症病毒性肝炎的病原学分析
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     STUDY OF TREATMENT FOR FULMINANT HEPATITIS
     重症肝炎治疗的研究
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     Hepatitis B Virus
     乙型肝炎病毒
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     HEPATITIS A
     A型肝炎
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Liver biopsies were performed in 110 cases of deep-jaundiced viral hepatitis of different types. Fulminant hepatitis showed two different types of liver cell damage. One was severe swelling of liver cells with foci of ceil necrosis of various extent, the mortality of this type was low (3/16). Theother type was characterized by massive cell necrosis, all of them died (3/3).The clinical diagnosis corresponded with the pathological findings in 66%. Thus liver biopsy might be used to correct the clinical...

Liver biopsies were performed in 110 cases of deep-jaundiced viral hepatitis of different types. Fulminant hepatitis showed two different types of liver cell damage. One was severe swelling of liver cells with foci of ceil necrosis of various extent, the mortality of this type was low (3/16). Theother type was characterized by massive cell necrosis, all of them died (3/3).The clinical diagnosis corresponded with the pathological findings in 66%. Thus liver biopsy might be used to correct the clinical misdiagnosis, offer a histological basis for evaluating the treatment and prognosis, and as a possible way,for studying the machanism of viral hepatitis.

110例黄疸深的各型病毒性肝炎作肝穿活组织检查,发现临床诊断为暴发型肝炎的病例有两种病理表现:一种是肝细胞严重肿胀伴有大小不等坏死灶病变,其病死率低(3/16)。另一种是肝细胞大块坏死病变,全部死亡(3/3)。本组临床诊断与病理相符者66%。因此,肝穿活检可纠正临床的误诊,并为临床评价疗效、判断预后提供病理依据,且将为研究其发病机制提供可能的途径。

We attempted to find criteria of clinical diagnosis of chronic active hepatitis ( CAH ) and raise clinical diagnosis rate through analysing clinical data of 104 cases of patients with CAR confirmed by pathological examination of liver biopsy. But clinical features and laboratory findings of patients with CAH are extremely different. The mild patients may have-no symptom at all, but the severe patients may mimic the patients with acut fulminant hepatitis. Clinical diagnosis is still difficult without the...

We attempted to find criteria of clinical diagnosis of chronic active hepatitis ( CAH ) and raise clinical diagnosis rate through analysing clinical data of 104 cases of patients with CAR confirmed by pathological examination of liver biopsy. But clinical features and laboratory findings of patients with CAH are extremely different. The mild patients may have-no symptom at all, but the severe patients may mimic the patients with acut fulminant hepatitis. Clinical diagnosis is still difficult without the pathological examination of liver biopsy. It is necessary to study how to-raise clirical diagnosis rate of CAH further.

我们企图通过104例肝穿活检病理检查确诊为慢性活动性肝炎的临床分析,找出慢性活动性肝炎的临床诊断标准,以提高临床诊断率。但慢性活动性肝炎的临床表现和实验室所见极为悬殊,轻者可无明显症状,重者则酷似急性重症肝炎,如无肝穿活检病理检查,临床诊断仍然困难。怎样提高临床诊断率仍待进一步研究。

Anti-HAV-IgM, anti-HBc-IgM, and three antibody systems of hepatitis B were tested in 48 patients with fulminant hepatitis to determine which of the hepatitis viruses A and B was the causative agent. HBV was found in 31 cases, HAV in one case, mixed infection of HBV and HAV in 15 cases (31.25%),and uncertain agent in 1 case.Ten cases out of the 15 with mixed infection were subacute, and the other 5 chronic. 13 patients were male and 2 female. The age of the patients ranged from 15 to 49 years with...

Anti-HAV-IgM, anti-HBc-IgM, and three antibody systems of hepatitis B were tested in 48 patients with fulminant hepatitis to determine which of the hepatitis viruses A and B was the causative agent. HBV was found in 31 cases, HAV in one case, mixed infection of HBV and HAV in 15 cases (31.25%),and uncertain agent in 1 case.Ten cases out of the 15 with mixed infection were subacute, and the other 5 chronic. 13 patients were male and 2 female. The age of the patients ranged from 15 to 49 years with an average of 30.39. The clinical conditions of 10 cases became more serious and some of them even died during hospitalization. The clinical and biochemical parameters of the patients with mixed infection showed no statistical difference from those of the patients with single infection of either HBV or HAV of the same time period. 7 patients complained of sudden aggravation of their clinical conditions after they exhibited a group of symptoms and signs of "acute icteric hepatitis". One such case was found during his hospitalization and his anti-HAV-IgM turned positive at the same time. This patient died eventually.It is considered that aggravation of acute or chronic hepatitis can be resulted from superinfection and this problem deserves close attention.

报告经血清免疫学抗HAVIgM、抗-HBcIgM、HBV-DNA、HBsAg/IgM复合物以及乙肝三种抗原抗体系统检测48例重型肝炎中甲、乙型肝炎病毒感染情况。结果:31例为HBV感染,1例为HAV感染,1例未定型,15例(31.25%)为甲、乙型合并感染(混合感染7例、重叠感染8例)。15例中亚急性10例、慢性5例;死亡或恶化10例,与同期“单纯”感染的重肝比较,包括主要临床生化指标均无显著差异。有7例患者病程中有近期出现“急黄肝”症状的历史,随后病情突然加重;1例发生在住院期间,且血清抗-HAVIgM转阳,最后死亡。认为合并感染可使部分急、慢性肝炎病情加重,甚至发展成重型。应注意发现。

 
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