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tetracycline
相关语句
  四环素
     Study on Drug Release Kinetics from Tetracycline Hydrochloride/α-TCP Bone Cement and in Vitro Dissolution Kinetics of α-TCP Bone Cement
     盐酸四环素/α-TCP骨水泥药物释放动力学及α-TCP骨水泥体外溶解动力学研究
短句来源
     Restoration of Tetracycline Resistance in a Hybrid Plasmid of pBR 322 by DNA Insertion
     DNA插入引起质粒四环素抗性的恢复
短句来源
     CONTINUED EFFECT OF TETRACYCLINE ON THE ELIMINATION OF CITRUS YELLOW SHOOT BY BUDWOOD IMMERSION
     四环素浸泡芽条消除柑桔黄龙病的持续效果
短句来源
     Polarographic Determination of Tetracycline
     四环素的极谱法测定
短句来源
     Studies of the Rare Earth Tetracycline Complex Ⅱ. Determination of the Stability Constants of La, Pr, Nd, Sna, Eu, Gd-Tetracycline Complexes
     稀土四环素络合物的研究Ⅱ.La~(3+)、Pr~(3+)、Nd~(3+)、Sm~(3+)、Eu~(3+)、Gd~(3+)——四环素络合物的稳定常数的测定
短句来源
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  “tetracycline”译为未确定词的双语例句
     Beer's law is obeyed for tetracycline (oxetracyclinum) in the range of 0.5~50μg/mL(0 6~50μg/mL) and the detection limit is 0.5μg/mL (0 6~50μg/mL).
     检出限分别为0.5μg/mL,0.6μg/mL,线性范围分别为0.5~50μg/mL和0.6~50μg/mL。
短句来源
     Finally,MIC90 of genta mycin and tetracycline ranged from 4.0 to 16.0 mg/L,the sensitive rate was 6 3.2~59.7%.
     庆大霉素、氯霉素其MIC90值为4.0~16.0mg/L,敏感率为63.2%~59.7%。
短句来源
     The cultured mycoplasma was sensitive to josamycin (97 7%), azithromycin (96 6%), doxycycline (94 3%), roxithromycin (90 9%), ofloxacin (88 6%), minocyclin (87 5%), norfloxacin (80 7%), spirmycin (73 9%), erythromycin (72 7%), and tetracycline (67%).
     药敏试验结果表明支原体对交沙霉素、阿奇霉素、强力霉素、罗红霉素最敏感 ,敏感率分别为 97 7%、96 6 %、94 3%、90 9% 其次为泰利必妥、美满霉素、诺氟沙星、螺旋霉素、红霉素 ,敏感率分别为 88 6 %、87 5 %、80 7%、73 9%、72 7%。
短句来源
     and those in PB061(ATDC+) were 0.56Gy,0.96Gy-1 and 0.10 respectively,the difference of α and SF2 value in PB061±tetracycline was significant.
     而BP061(ATDC+)组的D0值为0.56Gy,α值为0.96Gy-1,SF2为0.10。
短句来源
     gonorrhoeae (PPNG) was 16.0% and ~20.8% and the tetracycline resistant N.
     PPNG检出率药敏法为16.0%,PCR法为20.8;
短句来源
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  相似匹配句对
     Polarographic Determination of Tetracycline
     四环素的极谱法测定
短句来源
     362 cases with tetracycline;
     四环素组362例;
短句来源
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  tetracycline
The sensitivity of this method for gentamicin and streptomycin in the presence of blood serum amounted to 2.5 ± 0.5; for tetracycline, 45 ± 8 ng/ml.
      
Rate of Tetracycline Photolysis during Irradiation at 365 nm
      
Determination of Benzylpenicillin, Levomycetin (Chloramphenicol), and Tetracycline in Food Products by High-Performance Liquid C
      
The fluorescence of europium(III) in micellar solutions of surfactants sensitized by tetracycline derivatives was studied.
      
It was found that the fluorescence intensity in the system Eu3+-tetracycline derivatives increases in the presence of 1,10-phenanthroline by a factor of 3-4.
      
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Analogs of tetracycline and anhydrotetracycline were expected to be syn-thesised by condensation of 1, 4-anthraquinonoid compounds with suitable dienes.Synthesis of 1, 4, 4a, 5, 12, 12a-hexahydro-6-hydroxy-11-methyl-5, 12-diketonaphtha-cene (XI) by the action of 9, 10-dihydro-9-keto-10-methyl anthraquinone-[1, 4]with 1, 3-butadiene is reported. 3-Methyl-3-(2', 5'-dimethoxyphenyl) (VI), m. p. 79--80°, is obtainedby the action of 2-(2', 5'-dimethoxy benzoyl)-benzoic acid (V) with methylmagnesium iodide....

Analogs of tetracycline and anhydrotetracycline were expected to be syn-thesised by condensation of 1, 4-anthraquinonoid compounds with suitable dienes.Synthesis of 1, 4, 4a, 5, 12, 12a-hexahydro-6-hydroxy-11-methyl-5, 12-diketonaphtha-cene (XI) by the action of 9, 10-dihydro-9-keto-10-methyl anthraquinone-[1, 4]with 1, 3-butadiene is reported. 3-Methyl-3-(2', 5'-dimethoxyphenyl) (VI), m. p. 79--80°, is obtainedby the action of 2-(2', 5'-dimethoxy benzoyl)-benzoic acid (V) with methylmagnesium iodide. Reduction of VI by means of zinc-sodium hydroxide followedby cyclisation and demethylation affords 1, 4-dihydroxy-10-methyl-anthrone-[9](IX), m. p. 192--3°(dec.), which on oxidation with lead tetraacetate gives risealmost quantitatively to 9, 10-dihydro-9-keto-10-methyl-anthraquinone-[1,4] (X),m. p. 178.80°(dec.). Condensation of the latter with 1, 3-butadiene produces1, 4, 4a, 5, 12, 12a-hexahydro-6-hydroxy-11-methyl-5, 12-diketonaphthacene (XI), m. p.160--16l°, γ_(max)~(dioxane) 278 (∈76100), 378 (∈9800) mμ.

本文报告脱水四圜素同型物合成工作中一个模型试验,1,4,4a,5,12,12a-六氢-6-羟基-11-甲基-5,12-二羰基-并四苯合成的结果。 2-(2′,5′-二甲氧基苯甲酰)-苯甲酸(Ⅴ)经与碘化甲基镁作用,得3-甲基-3(2′,5′-二甲氧基苯)-隣苯甲醇甲酸内酯(Ⅵ),再经锌粉-氢氧化钠还原,得隣(α-甲基-2′,5′-二甲氧基)-苄基-苯甲酸(Ⅶ),浓硫酸环化变成1,4-二甲氧-10-甲基葱酮-[9](Ⅷ),用氢溴酸去甲基得1,4-二羟基-10-甲基蒽酮-[9](Ⅸ),以四乙酸铅氧化几乎全部变成9,10-二氢-9-羰基-10-甲基-蒽醌[1,4](Ⅹ)。Ⅹ和丁二烯-[1,3] 作用变为1,4,4a,5,12,12a-六氢-6-羟基-11-甲基-5,12-二羟基并四苯(Ⅺ)。

The separation, identification, and determination of epimer of tetracycline have been attempted paper-chromatographically based on the principle of Selzer's method. Some improvements were made to effect an efficient separation and identification. It was demonstrated experimentally that results from Selzer's method were not reliable owing to partial inversion of tetracycline in the course of chromatography. However, better results could be obtained through the modification of the solvent system. ...

The separation, identification, and determination of epimer of tetracycline have been attempted paper-chromatographically based on the principle of Selzer's method. Some improvements were made to effect an efficient separation and identification. It was demonstrated experimentally that results from Selzer's method were not reliable owing to partial inversion of tetracycline in the course of chromatography. However, better results could be obtained through the modification of the solvent system. In order to determine the epimer quantitatively, the chromatogram concerned was cut down and eluted many times with 0.1 N sulphuric acid. The optical density of the elute was then determined spectrophotometrically at 355 mμ, and finally by using E_(1cm)~(1%)=333 the quantity of epimer was worked out accordingly.

本文报告了四环素中差向异构体的紙上层析分离鉴定及定量方法。四环素中差向异构体的分离鉴定是在selzer法基础上加以改进的。本試驗証实該法在层析过程中有部分四环素轉化,結果不可靠,改进溶剂后可得到良好分离。四环素中差向异构体的定量是經层析后,将异构体部分剪下,以0.1N硫酸分多次洗下,再用分光光度計在355毫微米处測定,以E_1~(1%)值=333計算差向异构体的含量。

Problems concerning the toxicity of tetracycline, 4-epitetracycline, anhydrotetracycline and anhydro-4-epi-tetracycline are discussed in this paper. Among the above preparations, the 4-epi-tetracycline is most toxic to mice. When given intravenously its LD_(50) to mice is 85.8 mg/kg, as compared with 160.7 mg/kg of tetracycline, 134.2 mg/kg of anhydrotetracycline and 193 mg/kg of anhydro-4-epi-tetracycline. In sub-acute toxicity study anhydro-4-epi-tetracycline exhibited...

Problems concerning the toxicity of tetracycline, 4-epitetracycline, anhydrotetracycline and anhydro-4-epi-tetracycline are discussed in this paper. Among the above preparations, the 4-epi-tetracycline is most toxic to mice. When given intravenously its LD_(50) to mice is 85.8 mg/kg, as compared with 160.7 mg/kg of tetracycline, 134.2 mg/kg of anhydrotetracycline and 193 mg/kg of anhydro-4-epi-tetracycline. In sub-acute toxicity study anhydro-4-epi-tetracycline exhibited most toxic effects in mice. When given intravenously 1 mg/day, or even 12 mg/day orally, severe diabetic urine and proteinuria were observed, and serious pathologic change of the convoluted tube appeared. Our experiment indicates that anhydro-4-epi-tetracycline may be the chief material responsible for Fanconi syndrome.

本文比较了四环素,脱水四环素,叉向四环素及脫水叉向四环素的毒性。急性毒性以叉向四环素为最大,小白鼠靜脉LD_(50)为85.8毫克/公斤,而四环素,脫水四环素及脫水叉向四环素的LD_(50)分別为160.7毫克/公斤,134.2毫克/公斤及193毫克/公斤。亚急性毒性则以脫水叉向四环素为最大,小白鼠不论靜脉注射1毫克/0.5毫升或口服12毫克/0.2毫升,均能出现较重的糖尿及蛋白尿,肾曲管发生较重的病变,可能是临床引起Fanconi症候羣的主要物质。

 
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