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   antiproliferative activity 的翻译结果: 查询用时:0.172秒
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antiproliferative activity
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  “antiproliferative activity”译为未确定词的双语例句
     RESULTS: CN-2 was demonstrated to exert antiproliferative activity in a dose-and time-dependent manner. IC_ 50 of A549 after 24,48,72 h exposure to CN-2 was 108.20,41.28,20.67 mg/L,respectively. Typical apoptotic morphological changes were observed by electron microscope;
     结果CN-2对A549细胞增殖具有明显的剂量和时间依赖的抑制作用,24,48,72hIC50分别为108.20,41.28,20.67mg/L,电镜观察呈现典型的凋亡形态改变;
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     in the second round of screening, the antiproliferative activity of the full phosphorothioate ASODN complementary to the 287-306 region of the mRNA on HepG2 cells was 68.3±2.6%, with IC50 of 51.9±8.6 nmol/L.
     二次筛选显示互补于第287~306片段的全磷酸硫代修饰ASODN抗增殖作用最强,抑制率为(68.3±2.6)%,半数抑制浓度为(51.9±8.6)nmol/L。
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     IFN-λs,a Novel family of IFNs,including IFNλ-1、IFNλ-2 and IFNλ-3,can induce antiviral and antiproliferative activity and so on,which like type IFN Ⅰ,by Jak-STAT signaling through a heterodimeric class Ⅱ cytokine receptor consisting of CRF2-12/IFNLR1/IL-28Rα and CRF2-4/IL-10Rβ.
     IFN-λs的信号转导机制类似于IFN-α,两者都是通过诱导受体异二聚体化,活化Jak-STAT信号通路,进而发挥抗病毒、抗细胞增殖等生物学作用。 所不同的是IFN-λs是通过诱导其独特的Ⅱ型细胞因子受体CRF2-12/IFNLR1/IL-28Rα和CRF2-4/IL-10Rβ异二聚体化。
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     Antiproliferative activity of compounds 1、 2、 5、 7、 15 in human HL-60 leukemia cells were tested by growth inhibition method.
     采用细胞生长抑制计数法,对已鉴定结构的21个化合物中的1、2、5、7、15五个化合物进行体外抑制HL-60癌细胞活性研究。
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     Results DADAG had potential antiproliferative activity on human HL-60 cells and K562 cells,the IC 50 value was 3.7? μg·ml -1 and 25.5? μg·ml -1 ,respectively.
     结果 DADAG对HL60细胞和K562细胞有较强的抑制作用 ,IC50 值分别为 3 .7μg·ml- 1 和 2 5 .5μg·ml- 1 。
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     The activity of E.
     淀粉酶活性在50℃,pH 6.0条件下最高.
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     The antiproliferative activity of DFO increased in a dose dependent manner.
     DFO的抗增殖活性为时间-剂量依赖型。
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     The activity of OH-.
     OH.
短句来源
     The antiproliferative activity of DFO increased in a dose dependent manner.
     DFO抗细胞增殖活性为剂量依赖性。
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  antiproliferative activity
Synthesis and antiproliferative activity of 1-[(sub)]-6-fluoro-3-[(sub)]-1, 3,4-oxadiazol-2-yl-7-piperazino-1, 4-dihydro-4-quino
      
The conventional and predictive correlation coefficients were found to be 0.725 and 0.577 for the antiproliferative activity of aminophenylbenzamides and acrylamide series, respectively.
      
The study indicated that their antiproliferative activity is largely explained by the steric factors of the substituents, highlighting the role of the size and shape of the inhibitor in forming effective binding interactions with histone deacetylase.
      
195-201), already contains the IFN-α 130-137 fragment and possesses antiproliferative activity comparable with that of IFN-α2.
      
Studies on the dose dependent effects of the flavonoids showed antiproliferative activity of all compounds with EC50 values ranging between 39.7 ± 2.3 μM (baicalein) and 203.6 ± 15.5 μM (diosmin).
      
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The effect of crystalline trichosanthin on two tumour cell lines , Jar(human choriocarcinom a )and Hela (human carcinoma of cervix), and one normal cell line Fib (human normal skin fibroblast ) was studied. Trichosanthin exerts a selective antiproliferative activity towards the Jar cells as determined by the total protein assay of survival cells and hCG sercretion (in Jar). ID50 is around 3.3μg/ml for Jar cells compared to 13.0 μg/ml for Hela and 16.0 μ g/ml for Fib cells after 48 hour incubation. The...

The effect of crystalline trichosanthin on two tumour cell lines , Jar(human choriocarcinom a )and Hela (human carcinoma of cervix), and one normal cell line Fib (human normal skin fibroblast ) was studied. Trichosanthin exerts a selective antiproliferative activity towards the Jar cells as determined by the total protein assay of survival cells and hCG sercretion (in Jar). ID50 is around 3.3μg/ml for Jar cells compared to 13.0 μg/ml for Hela and 16.0 μ g/ml for Fib cells after 48 hour incubation. The mechanism of this selective antitum our activity is discussedd.

结晶天花粉蛋白对Jar人绒癌细胞的增殖有明显的抑制作用,培育48小时后的ID50为3.3μg/ml:而Hela人宫颈癌细胞和正常纤维细胞的ID50分别为13.0和16.0μg/ml。此外,结晶天花粉蛋白对Jar细胞的hCG分泌显示更强的抑制作用,培养48小时后,抑制50%hCG分泌的结晶天花粉浓度为1.3μg/ml。文中并对天花粉蛋白的选择性抑制作用的机理,加以讨论。

tilizing three human tumor cell lines as models,we analyzed the effects of sequence,dose and time on the antiproliferative activity of combinations of tumor necrosis fatcor β(β TNF)and interferon γ(γ IFN).The results could provide some experimental basis for the clinical use of β TNF and γ IFN.

采用3个人肿瘤细胞株为模型,分析了给药顺序、剂量和时间等因素对γ-干扰素和β-肿瘤坏死因子联合应用抗增殖的影响。本结果为临床设计肿瘤治疗方案提供了一定的实验依据

Antitumor activity of quercetin and tumor associated gene expressiong are studied.These results demonstrate a direct correlation between the antiproliferative activity of quercetin on variety of tumors and the amount of gene expression.Obviously,further studies at the molecular level are necessary to understand the mechanism of regulation of gene and how quercetin affects these processes.

本文主要综述了槲皮素抗肿瘤作用与相关基因调控的最新进展,探讨了槲皮素对相关基因的调控机理,指出对新的抗癌剂槲皮素的研究,具有重要的理论意义和应用前景

 
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