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   urinary recovery 的翻译结果: 查询用时:0.179秒
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urinary recovery
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  尿药回收率
     (3) The 12h urinary recovery rate of groups were 87.46% and 87.18%, respectively.
     (3) 12 h尿药回收率分别为 87.46 %和 87.18%。
短句来源
     Urinary recovery rates of piperacillin alone and in compound between 0 to 12h were(55.4±22.0)% and(43.6±12.3)% respectively.
     12h尿药回收率分别为(55.4±22.0)%和(43.6±12.3)%。
短句来源
     The urinary recovery rates in 12h of the two groups were ( 55.7 ± 4.0 )% and ( 56.1 ± 3.0 )%,respectively.
     12h尿药回收率分别为 ( 5 5 .7± 4 .0 ) %和 ( 5 6.1± 3 .0 ) %。
短句来源
     The urinary recovery rates(0~48 h)were:56.67%and52.25%.
     0~48h尿药回收率分别为:56.67%和52.25%。
短句来源
     We examined the 48-h urinary recovery of healthy volunteers for dose of 200 mg and ths 24-h urinary recovery of fast and non-fast rats for dose of 50 mg/L, they were 26.79%, 8.41% and 3.98%, respectively.
     同时,还测定了健康志愿者空腹口服环丙氟哌酸200mg及禁食与非禁食大鼠口服50mg/kg后48小时和24小时尿药回收率,分别为26.79%和8.41%、3.98%。
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  尿排出
     The urinary recovery rate of enoxacin over 24h was 52.8% for powder and 54.5% for tablets. The effective urine concentration was maintained for 12~24h.
     单剂空腹口服原粉、片剂400mg后24h的尿排出率为52.8%和54.5%,有效尿浓度可维持至12~24h之久。
短句来源
     The urinary recovery rate within 24 hourswas around 70% after iv, iv infusion and im administraton of the drug.
     24小时内尿排出率为给药量的70%。
短句来源
     Cefadroxil was mainly excreted through kidney. The urinary recovery rate of drug over 24h was above 90%. Based on the pharmacokinetic parameters,a therapeutic regimen is suggested for the treatment of bacterial in fections.
     口服该药主要自肾排出,24h尿排出率为药量的90%左右,根据药动学参数,提出治疗细菌感染的给药方案。
短句来源
     The relative bioavailability of domestic azithromycin capsule was 97.79%,compared with the imported one. The urinary recovery rate of the azithromycin was 11.29% during the period of 144 h after oral adminstration of domestic capsule.
     与进口阿奇霉素比较,国产阿奇霉素胶囊的相对生物利用度为97.79%,口服该药144h尿排出率为给药量的11.29%。
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  “urinary recovery”译为未确定词的双语例句
     Urinary recovery rates were (87. 27 ± 10. 31)% and (90. 45 ±6. 47)% of two doses, respectively.
     尿药浓度测定结果表明,帕珠沙星0-24 h累积排出量分别为(261.82±30.92)mg和(452.27±32.35)mg,0-24 h累积排出百分比分别为(87.27±10.31)%和(90.45±6.47)%。
短句来源
     The urinary recovery of unchanged drug in24 hr after administration was 29.63%.
     24小时尿中回收原型药物为给药剂量的29.63%。
短句来源
     The elimination half life and the apparent volume of distribution ranged from 4. 15 to 4. 82h and 157. 3 to 210. 71. The urinary recovery rate of enoxacin over 24h after dosing was morethan 50%, ranged from 51. 20-54. 60%.
     其消除半衰期为4.15~4.82h,表观分布容积为157.3~210.71。 氟啶酸自尿中排出给药量的51.20~54.66%。
短句来源
     RESULTS In comparison with mice as control, the urinary recovery of MEGX increased by 35.0% and 23.4% ( P <0.05);
     结果 与正常对照组相比 ,地塞米松组小鼠 MEGX累积排泄量增加 35 .0 % (P<0 .0 5 ) ,P45 0 3A酶蛋白含量增加 147.1% (P<0 .0 1) ;
短句来源
     the Vd were 13.48 ±2.94,13.93±2.40L; respectively. Urinary recovery rates were (60.11±5.20)% and (61.23 ±9.81)% of two doses in 12 h, respectively.
     12 h原形药物在尿中累积排泄百分率分别为(60.11±5.20)%与(61.23±9.81)%。
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  urinary recovery
anhydrous ampicillin, attained after one hour, was 5.2 μg/ml.; mean urinary recovery was 72.2%.
      
Urinary recovery rates were 57-80% after four hours and 75-100% after 24 hours.
      
The urinary recovery after bacampicillin was 68-75% as compared to 25-41% after ampicillin.
      
Average urinary recovery within eight hours was as low as 26.8%, which suggested accumulation of this antibiotic in the renal tissue.
      
Urinary recovery within 48 hr was 45% to 106% when CCr >amp;gt; 8 ml/min.
      
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The study was carried out in a test group of six partially gastrotomized human volunteers by the urinary excretion method and results obtained were compared with a control group of nine healthy human volunteers. Both groups received three riboflavin solid dosage forms with two different dosage regimens in a crossover design. The observed data were fitted to a two compartment model by using the PKP Ⅱ (2) digital computer program on a microcomputer for both dosage regimens for each subject.A significant difference...

The study was carried out in a test group of six partially gastrotomized human volunteers by the urinary excretion method and results obtained were compared with a control group of nine healthy human volunteers. Both groups received three riboflavin solid dosage forms with two different dosage regimens in a crossover design. The observed data were fitted to a two compartment model by using the PKP Ⅱ (2) digital computer program on a microcomputer for both dosage regimens for each subject.A significant difference in the amount of excretion of riboflavin was found between the two groups, urinary recovery of riboflavin was lower in the test group than in the control group (P<0.01). In comparing the pharmacokinetic parameters, Ka was significantly greater and Tmax was significantly less in the test group than in the control group, but no statistically significant difference in the values of β was observed.These differences are attributed to gastric emptying rates as well as the dissolution rates of the dosage forms.These results suggest that it is practically possible to increase the bioavailability of persons after partial gastroctomy by administering rapid release preparations or by multiple dosage regimen,

以胃大部切除术(Billroth Ⅰ式)后已恢复健康的人为对象,研究核黄素的不同剂型、不同给药方法的生物利用度及动力学参数,将结果与正常人对比(对照组),探讨提高生物利用度的方法。数据处理按PKPⅡ(2)程序在微型计算机上进行。结果表明,胃大部切除者的核黄素口服吸收率低于正常人,而吸收速度大于正常人,动力学参数Ka、Tmax在胃切除组与对照组间可有非常显著或显著的差异,而β无显著差异。作者认为提高胃大部切除者的核黄素生物利用度,可通过制成释放速度较快的制剂或采用小剂量多次给药的方案来实现。

The quantitative determination of furbenicillin in bodyfluids of normal subjects was investigated with a hign-performence liquidchromatograpny (HPLC). The furbenicillin and the chloro-furbenicillin ad-ded as an internal standard were extracted, from urine and serum samples, with cthyl acetate and then re-extracted into sodium hydroxide. The sodiumhydroxide extracts were injected onto the column. The results showed thatthe HPLC method was sensitive, specifical, accurate and precision, andcan therefore be used...

The quantitative determination of furbenicillin in bodyfluids of normal subjects was investigated with a hign-performence liquidchromatograpny (HPLC). The furbenicillin and the chloro-furbenicillin ad-ded as an internal standard were extracted, from urine and serum samples, with cthyl acetate and then re-extracted into sodium hydroxide. The sodiumhydroxide extracts were injected onto the column. The results showed thatthe HPLC method was sensitive, specifical, accurate and precision, andcan therefore be used for the study of clinical pharmacology. The pharmacokinetics of furbenicillin in normal subjects after i. v.bolus injection was studied by the HPLC method. The drug concentration-time curve was a two-compartment open model with an equition Ct=145. 8e~(-2:47t)+18.5e~(-0:64t). The mean peak serum level was 178.3mg/l;the elimination half-life (T1/2β) was 1.08 hr and the apparent volume ofdistribution was 17.69 littres. The urinary recovery of unchanged drug in24 hr after administration was 29.63%.

本文报告建立高效液相色谱法测定我国发展成功的呋苄青霉素体液中药物浓度。本法用氯呋苄青霉素作为内标物。固定相为Partisil ODS,10μm;流动相为甲醇/磷酸盐缓冲液,紫外检测波长为275nm,流动相流速为1.5ml/min。方法学多种指标考核表明该法灵敏、特异、准确、精密,可用于呋苄青霉素临床药理研究。正常人静脉注射呋苄青霉素1.0克,药代动力学符合二室开放式模型。药代动力力学方程为Ct=145.8~(e-2?47t)+18.5e~(-0?64t)。即刻血清峰浓度为178.3mg/L,消除半衰期T_(1/2β)为1.08小时,表观分布容积Vd为17.69升;24小时尿中回收原型药物为给药剂量的29.63%。

Leucomycin(LM) is a macrolide antibiotic. It has strong antibacterial effect against Gram-positive organisms,some Gram-negative coccus, Ieptospira, ricke-ttsiat especially aganist penicillin, erythromycin and tetracycline-resistent S. aurens, Streptococcus hemolyttcus and Streptococcus pneumontae.The pharmacokinetics of LM was studied, the dynamic changes of drug level in serum and urine for enteric coated LM were observed. The drug concentration was m-easured by bioassay method and the serum drug level-time...

Leucomycin(LM) is a macrolide antibiotic. It has strong antibacterial effect against Gram-positive organisms,some Gram-negative coccus, Ieptospira, ricke-ttsiat especially aganist penicillin, erythromycin and tetracycline-resistent S. aurens, Streptococcus hemolyttcus and Streptococcus pneumontae.The pharmacokinetics of LM was studied, the dynamic changes of drug level in serum and urine for enteric coated LM were observed. The drug concentration was m-easured by bioassay method and the serum drug level-time profile of LM conformed to the one compartment open model by p. o. administration.After oral administration of 267mg LM.the C_DK for gastric and enteric coated LM capsules were 0.147 and 0.97 μg/ml, respectively. For gastric coated LM capsule, T1/2ka. T1/2ke,MRT, MAT were 0.13, 0.72, 1.22 and O.l8hour,respectively. T_pk was 0.5 hour. For enteric coated LM, the Tpk was 5 hour and the drug level decreased rapidly. Within 24 hours, only a small portion of LM was elimineted from urine. The urinary recovery rate for gastric coated and enteric coated LM was only 7.64‰ and 11.54‰, respectively.In the multiple-dosage group of enteric coated LM capsule, the peak serum level could reach 0.42-0.68μg/ml. It was much higher than that in single dose group.It must be noted that after oral administration of gastric coated LM capsule, the C-T curve showed double peaks. This phenomenon may be caused by enteric-hepatic circulation and equation for non-compartment model should be used in the calculation of pharmacokinetic indices.

本文报道了柱晶白霉素(LM)胃溶片的人体药代动力学研究结果,并对肠溶片口服后的血、尿中药物浓度作了动态观察。血、尿药物浓度用微生物杯碟法测定。健康志愿者分别口服柱晶白霉素胃溶片和肠溶片40万单位(相当于267mg)后,体内药物转运过程均符合一室开放模型。两种制剂的血药浓度达峰时间、峰浓度分别为0.5小时,0.94μg/ml和5小时,0.147μg/ml。其中胃溶片口服后的T(1/2)Ka和T(1/2)Ke分别为0.13和0.72小时,而MRT为1.22小时,MAT为0.18小时。 口服LM肠溶片多剂量组,从第2天起,血药峰浓度波动于0.42~0.68μg/ml,显著高于单剂量组的峰浓度,其谷浓度则波动于0.05~0.34μg /ml。 LM的肾排泄率极低,口服LM的胃溶片和肠溶片后24小时内,从尿中排出的药量仅占给药量的7.64‰和11.54‰。口服LM胃溶片后的C-T曲线出现双峰,可能与肠肝循环有关,在计算药动学参数时应予注意。

 
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