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ions response
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     Effects of some metallic ions on electrode response were studied.
     研究了某些金属离子对电极响应的影响。
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     evaluation and response;
     评价与反馈;
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     EFFECTS OF HEAVY METAL IONS ON COUGH RESPONSE OF MUD CARP
     重金属离子(Hg~(2+),Cu~(2+),Ag~+)对鲮鱼咳嗽反应的影响
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     The Challenge and Response
     挑战与回应——全球化背景下公共行政变革的生态学解析
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     K+ ions.
     对Na~+、K~+呈一元酸特性。
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A Dual ISFET based on integrated process is presented The experimental results show that its H+-ion sensing characteristic is good. The H+-ion response feature of constant current electronic is improved by differential amplifer, and other unsteady factors, such as temperature drift, the drift etc., are effectively rejected. Using noble metal film as a counter-electrode of an ideal reference electrode, we can also obtain good results.

报道了采用集成技术制备的差分对结构pH-ISFTET传感器及其特性,实验结果表明,ISFET器件性能良好,经差分放大器输出可以改善恒流电路测量的响应特性,且有效地抑制温漂、时漂等不稳定因素。采用金膜辅助电极替代甘汞参考电极的差分测量仍有较好的结果。

PURPOSE: To know whether the cardiac function of the patients with heart disease is impaired or improved after long-term taking β-AR antagonists. METHODS: After giving the rats β-AR selective antagonist, atenolol, for 12wk, the method of radioligand binding assay and the experiment of isolated left-atrium contractive function were carried out to observe the quantity and distribution of β-AR, its subtypes, α-AR, and the change of left - atrium contractive function. RESULTS: After long-term administration of atenolol,...

PURPOSE: To know whether the cardiac function of the patients with heart disease is impaired or improved after long-term taking β-AR antagonists. METHODS: After giving the rats β-AR selective antagonist, atenolol, for 12wk, the method of radioligand binding assay and the experiment of isolated left-atrium contractive function were carried out to observe the quantity and distribution of β-AR, its subtypes, α-AR, and the change of left - atrium contractive function. RESULTS: After long-term administration of atenolol, there were no any obvious changes in α-AR, the density of the total β-AR, β1-AR, and the proportion of β2-AR in tota1 amount of β-AR, but the con centrat ion - response cu rves shi fted l e ftwa rd s si gn ifi cant ly as compared with control group- The PA2 value of isoprotenol(ISO) - induced positive inotropic effect after antagonized by β1-AR selective antagonist CGP20712A in atenolol group was increased significantly as compared with control group. But the PKB value after antagonized by ICI 118511 showed no obvious difference between two groups. HPLC detection showed that the level of plasma atenolol was 3. 5pmol/L in atenolol group and the leveIs of plasma norepinephrine had no significant difference between two groups. But the level of plasma adrenaline in atenolol group was obviously lower than that in control group. CONCLUSIO- N: The long-term administration of βl-AR antagonist will cause significant increase of the sensitivity of heart β-AR, especially β1-AR to excitant ISO. But the number of β-AR and its subtypes did not change significantly. Besides, after the long-term administration of β1-AR antagonist atenolol, the level of plasma adrenaline in rats was much lower than that in control group.

目的:了解心脏病患者长期服用β-受体桔抗剂后,心功能究竟能否得到改善。方法:给大鼠服用选择性β1-受体桔抗剂氨酰心安12wk后,采用放射配体结合实验和离体左心房收缩功能实验,观察大鼠心脏β-受体及其亚型和α1-受体的数量、分布以及左心房收缩功能的改变。结果:长期服用氨酰心安后心脏α1-受体、总β-受体的密度和β1-受体、β2-受体亚型所占β-受体总数的比例均无明显改变。但氨酰心安组左心房异丙肾上腺素的浓度-收缩效应曲线较对照组明显左移。氨酰心安组的选择性β1-受体桔抗剂 CGP20712A桔抗异丙肾上腺素介导的正性变力效应的 PA2值显著大于对照组;而 ICI 118551桔抗异丙肾上腺素的PKB值在两组间无显著性差异。用高效液相色谱法测定氨酰心安组血浆氨酰心安浓度为3.5umol/L,血浆中去甲肾上腺素水平两组间无显著性区别,但氨酰心安组血浆肾上腺素水平明显低于对照组。结论:长期服用β1-受体桔抗剂后,心脏β-受体对激动剂异丙肾上腺素的敏感性明显增强,且以β1-受体的敏感性增强更为显著。但β-受体及其亚型的受体数目并无明显改变。此外,长期服用β1-受体桔抗剂后,服用氨酰心安组大鼠的血浆肾上腺素水平明显低于对...

目的:了解心脏病患者长期服用β-受体桔抗剂后,心功能究竟能否得到改善。方法:给大鼠服用选择性β1-受体桔抗剂氨酰心安12wk后,采用放射配体结合实验和离体左心房收缩功能实验,观察大鼠心脏β-受体及其亚型和α1-受体的数量、分布以及左心房收缩功能的改变。结果:长期服用氨酰心安后心脏α1-受体、总β-受体的密度和β1-受体、β2-受体亚型所占β-受体总数的比例均无明显改变。但氨酰心安组左心房异丙肾上腺素的浓度-收缩效应曲线较对照组明显左移。氨酰心安组的选择性β1-受体桔抗剂 CGP20712A桔抗异丙肾上腺素介导的正性变力效应的 PA2值显著大于对照组;而 ICI 118551桔抗异丙肾上腺素的PKB值在两组间无显著性差异。用高效液相色谱法测定氨酰心安组血浆氨酰心安浓度为3.5umol/L,血浆中去甲肾上腺素水平两组间无显著性区别,但氨酰心安组血浆肾上腺素水平明显低于对照组。结论:长期服用β1-受体桔抗剂后,心脏β-受体对激动剂异丙肾上腺素的敏感性明显增强,且以β1-受体的敏感性增强更为显著。但β-受体及其亚型的受体数目并无明显改变。此外,长期服用β1-受体桔抗剂后,服用氨酰心安组大鼠的血浆肾上腺素水平明显低于对照?

 
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