助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   eosinophilic inflammation 的翻译结果: 查询用时:0.01秒
图标索引 在分类学科中查询
所有学科
药学
更多类别查询

图标索引 历史查询
 

eosinophilic inflammation
相关语句
  嗜酸性粒细胞炎症
     Effect of Bambuterol on Eosinophilic Inflammation of Airway in Asthmatic Guinea Pigs and Its Mechanism
     班布特罗对哮喘豚鼠气道嗜酸性粒细胞炎症的作用机理研究
短句来源
  “eosinophilic inflammation”译为未确定词的双语例句
     Growing evidence suggests that inducible nitric oxide synthase (iNOS) is the main source of the high output of exhaled NO (FENO) in asthma, which correlates with the severity of asthma and eosinophilic inflammation.
     越来越多的实验提示诱导型一氧化氮合酶(iNOS)是哮喘呼出气中NO的主要来源,而呼出气中NO浓度(FENO)与哮喘炎症过程及哮喘严重程度相关,可作为哮喘发作及控制的指标。
短句来源
     Overproduction of IL 13 has been shown to induce airway hyperresponsivess, eosinophilic inflammation,mucus hypersecretion, and subepithelial fibrosis. IL 13R is a functional component of the IL 4R complex. The signal transduction pathways of IL 13 are through JAK/STAT, Fes, phosphatases, and BCL 6/SOCS.
     IL 13信号转导途径除了JAK/STAT6以外 ,尚有IRS 1、Fes、磷酸激酶、BCL 6 /SOCS等途径
短句来源
     Conclusions IL 16 is involved in the asthmatic process by recruiting CD + 4 T cells and thus plays an important role in CD + 4 cell dependent eosinophilic inflammation in asthmatic airways.
     结论IL16参与了哮喘的发病过程,其机制可能是通过募集CD+4T细胞从而在CD+4T细胞所介导的哮喘气道嗜酸细胞炎症反应中发挥作用。
短句来源
     Objective To elucidate the roles of interleukin-5 (IL-5),Eotaxin,and CCR-3 in eosinophilic inflammation in guinea pig asthma models and investigate the inhibitory effects of Galectin-3. Methods Thirty-two guinea pigs were randomly assigned to control group,asthma group,Galectin-3 intervention group,and dexamethasone (DXM) intervention group.
     目的 观察哮喘豚鼠模型中白细胞介素- 5 (IL - 5 )、Eotaxin和C- C趋化因子受体3(CCR- 3)在嗜酸粒细胞炎症中的表达和Galectin- 3的干预作用。 方法 32只豚鼠随机分为正常对照组、哮喘组、Galectin- 3干预组和地塞米松(DXM)干预组。
短句来源
     Objective (1) To investigate the concentration, source and significance of serum interleukin-5 (IL-5) in children with allergic asthma. (2) To investigate the effect of IL-5 on eosinophilic inflammation in asthmatic airways in vivo. (3) To investigate the role of IL-5 in the mechanism of airway hyperresposiveness.
     目的 (1)了解过敏性支气管哮喘患儿血清白细胞介素-5(IL-5)的水平、来源及其意义:(2)研究IL-5对哮喘患者气道嗜酸性粒细胞(EOS)性炎症的影响;
短句来源
更多       
  相似匹配句对
     Inflammation
     炎症(1)
短句来源
     Eosinophilic airway inflammation and airway hy-perresponsiveness
     嗜酸粒细胞性气道炎症与气道高反应性
短句来源
     Pathological features of airway inflammation in eosinophilic bronchitis
     嗜酸粒细胞性支气管炎气道炎症病理特征的探讨
短句来源
     Inflammation and Atherosclerosis
     炎症与动脉粥样硬化
短句来源
     Eosinophilic cystitis in children
     儿童嗜酸性膀胱炎的临床及CT表现
短句来源
查询“eosinophilic inflammation”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  eosinophilic inflammation
Eosinophil cationic protein (ECP) is a ribonuclease secreted from activated eosinophils that may cause tissue injure as a result of eosinophilic inflammation.
      
The OVA-FlaB treatment significantly suppressed OVA-induced airway hyperresponsiveness, airway eosinophilic inflammation, and OVA-specific Th2 cytokine productions in splenocytes.
      
In this study we investigate whether BCG infection in ovalbumin (OVA)-presensitized Sprague-Dawley rats suppresses airway hyperresponsiveness and eosinophilic inflammation induced by OVA and Th2 cytokine production.
      
Eosinophilic inflammation and airway remodeling are features of asthma.
      
There is increasing evidence that inflammatory mechanisms other than atopy or eosinophilic inflammation may be involved in the pathogenesis of asthma.
      
更多          


In order to investigate the role of interleukin(IL) 5 in the eosinophilic inflammation of asthmatic airways,eight nonsmokin patients with allergic asthma were treated with recombinant human IL 5 by nebulization The levels of the eosinophil cationic protein(ECP) in the sputum were determined before,and at 2,24,48 h after inhalation Results:Comparing with the pre inhalation baseline value(279 5±45 5 μg/L),inhalation of IL 5 led to a gradual increase of ECPlevels,reaching a maximum value at 24 h(773...

In order to investigate the role of interleukin(IL) 5 in the eosinophilic inflammation of asthmatic airways,eight nonsmokin patients with allergic asthma were treated with recombinant human IL 5 by nebulization The levels of the eosinophil cationic protein(ECP) in the sputum were determined before,and at 2,24,48 h after inhalation Results:Comparing with the pre inhalation baseline value(279 5±45 5 μg/L),inhalation of IL 5 led to a gradual increase of ECPlevels,reaching a maximum value at 24 h(773 5±97 9 μg/L,P<0 01),which lasted at least 48 h(738 5±89 5 μg/L,P<0 01) The results indicate that IL 5 not only can induce eosinophilic infiltration of the asthmatic airways,but also can activate the eosinophils

为探讨白细胞介素-5(IL-5)在支气管哮喘患者气道炎症过程中的作用,随机选择8例哮喘患者雾化吸入人重组IL-5,并分别于吸入前、吸入后2h、24h和48h以放射免疫法测定痰液中嗜酸阳离子蛋白(ECP)水平。结果发现吸入IL-5后ECP水平均随时间而明显升高,至24h达最高值,48h后仍维持在较高水平。这些资料提示IL-5不仅可以直接趋化嗜酸性粒细胞浸润到哮喘患者的呼吸道,而且还能招致其活化从而参与哮喘的发病过程。

Objective:To observe the effects of inhaled interleukin 5(IL 5) on the changes of concentrations of soluable intracellular adhesion molecule 1 (sICAM 1) in serum from both allergic asthmatics and non allergic healthy subjects. Methods:In a randomized double blind, placebo controlled study design, eight nonsmoking patients with allergic asthma and six normal control subjects were administered recombinant human IL 5 by nebulization, and the concentrations of soluble(s)ICAM 1 in serum from each subject...

Objective:To observe the effects of inhaled interleukin 5(IL 5) on the changes of concentrations of soluable intracellular adhesion molecule 1 (sICAM 1) in serum from both allergic asthmatics and non allergic healthy subjects. Methods:In a randomized double blind, placebo controlled study design, eight nonsmoking patients with allergic asthma and six normal control subjects were administered recombinant human IL 5 by nebulization, and the concentrations of soluble(s)ICAM 1 in serum from each subject were determined before, and at 2, 24, 48, 72h after inhalation, respectively. Results:sICAM 1 levels in serum within the control group did not change from the baseline at any time throughout the study. In allergic asthmatics, vehicle challenge was not able to cause any changes in sICAM 1 levels in serum. However, there was an increase in serum sICAM 1 levels after IL 5 inhalation, which was significantly greater than the baseline value, reaching a maximum at 48h, and lasted no less than 72h. Conclusions:IL 5 was capable of inducing elevations of serum sICAM 1 concentrations in allergic asthmatics, but not in normal control subjects. The results also suggest that sICAM 1 might he an important effector in the mechanism by which IL 5 induces airway hyperresponsiveness and eosinophilic inflammation in allergic asthmatics.

目的:观察白细胞介素-5(IL-5)经雾化吸入后对过敏性哮喘患者和正常人血清中可溶性粘附分子-1(sICAM-1)水平变化的影响。方法:于IL-5吸入前、吸入后2、24、48及72h分别收集8例哮喘患者和6名正常对照者的血清,并以酶联免疫吸附法测定其中sICAM-1水平。结果:IL-5对正常人血清中的sICAM-1水平均无影响。哮喘患者吸入IL-5后2hsICAM-1即明显增高,48h后达最大值,而这种高水平的sICAM-1至少可以维持72h。结论:IL-5可以明显提高哮喘患者而不是正常人的sICAM-1水平;IL-5导致哮喘气道炎症和气道高反应性的一个机制很可能是通过sICAM-1而实现的

Objective To explore the significance of in the terleukin 16 (IL 16) in pathogenesis of bronchial asthma. Methods Induced sputum samples were obtained from 12 allergic asthmatics, 8 non allergic asthmatics,10 non asthma allergic and 10 non asthma non allergic normal subjects. ELISA was used to determine the concentrations of IL 16 in sputum,and CD + 4 T cells and activated eosinophils (EG 2 cells) in sputum were detected by immunostaining. Results IL 16 levels in both allergic and non allergic...

Objective To explore the significance of in the terleukin 16 (IL 16) in pathogenesis of bronchial asthma. Methods Induced sputum samples were obtained from 12 allergic asthmatics, 8 non allergic asthmatics,10 non asthma allergic and 10 non asthma non allergic normal subjects. ELISA was used to determine the concentrations of IL 16 in sputum,and CD + 4 T cells and activated eosinophils (EG 2 cells) in sputum were detected by immunostaining. Results IL 16 levels in both allergic and non allergic asthmatics were much higher than those in non asthma allergic or non asthma non allergic normal subjects. Effective anti asthma treatment led to a significant decrease in IL 16 levels in patients with acute asthma. It was also found that the percentages of CD + 4 and EG 2 cells were all positively correlated to IL 16 levels. Conclusions IL 16 is involved in the asthmatic process by recruiting CD + 4 T cells and thus plays an important role in CD + 4 cell dependent eosinophilic inflammation in asthmatic airways.

目的探讨白细胞介素16(IL16)在支气管哮喘发病机制中的作用。方法收集12例过敏性哮喘患者、8例非过敏性哮喘患者、10例过敏性体质患者和10名正常对照者的痰液,以酶联免疫吸附测定法测定痰中IL16的含量,并以免疫染色技术检测CD+4细胞和活化嗜酸细胞(EG2细胞)数。结果哮喘患者无论是过敏性还是非过敏性,痰液中IL16水平与过敏体质但无哮喘的患者和正常组比较,差异有显著性(P<0.01)。急性发作期哮喘患者经治疗后IL16水平能达缓解期水平。此外,痰液中CD+4细胞和IL16水平比较呈显著正相关(r=0.76,P<0.01),痰液中EG2细胞数与IL16水平呈显著正相关(r=0.61,P<0.01)。结论IL16参与了哮喘的发病过程,其机制可能是通过募集CD+4T细胞从而在CD+4T细胞所介导的哮喘气道嗜酸细胞炎症反应中发挥作用。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关eosinophilic inflammation的内容
在知识搜索中查有关eosinophilic inflammation的内容
在数字搜索中查有关eosinophilic inflammation的内容
在概念知识元中查有关eosinophilic inflammation的内容
在学术趋势中查有关eosinophilic inflammation的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社