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   osteogenesis 在 临床医学 分类中 的翻译结果: 查询用时:0.013秒
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osteogenesis
相关语句
  骨生成
    The effect of the bone resorption and osteogenesis in postmenopausal osteoporosis's patients with ~(99) Tc-MDP
    ~(99)Tc-MDP对绝经后骨质疏松骨吸收、骨生成的影响
短句来源
  成骨作用
    Osteogenesis induced by rhBMP-2 enhanced by TGF-βin vivo
    骨诱导和骨形成机制的研究:β转化生长因子增强人重组骨形态发生蛋白-2在体内的诱导成骨作用
短句来源
    SDB has the same osteogenesis induction effect as DBM.
    SDB具有与DBM相似的诱导成骨作用
短句来源
    Objective To observe osteogenesis of percutaneous autogenous bone marrow into cicatrix of bone defect.
    目的观察经皮自体骨髓移植在骨缺损瘢痕组织内的成骨作用
短句来源
    Conclusion Autogenous bone marrow can induce osteogenesis in cicatric bone defect, whereas no osteogenesis is found in the peripheral blood injection side.
    结论经皮自体骨髓注射在骨缺损区的瘢痕组织内有明显成骨作用,外周血注射不能成骨。
短句来源
    Objective To study the osteogenesis of partially deplroteinised bone(PDB) used as a scalfold of osteoblasts.
    目的探讨部分脱蛋白骨(PDB)作为成骨细胞支架材料体内植入的成骨作用
短句来源
  “osteogenesis”译为未确定词的双语例句
    Experimental study of stimulation of periosteal osteogenesis by transforming growth factor β and recombinant human bone morphogenetic protein 2
    转化生长因子-β和重组人骨形成蛋白-2刺激骨膜成骨的实验研究
短句来源
    Radiological Diagnosis of Osteogenesis Imperfecta (Analysis of 21 Cases)
    成骨不全的X线诊断(附21例分析)
短句来源
    X-ray Diagnosis of Osteogenesis Imperfecta:A Report of 10 Cases and Literature Review
    成骨不全症的X线诊断(附10例报告及文献复习)
短句来源
    Materials and Methods: The clinical manifestations and X-ray features of 21 cases (fetus 1 case, new-born baby 6 cases, infant 4 cases, children 6 cases, adult 4 cases) of osteogenesis imperfecta were reported and analysed.
    资料与方法:报告21例(胎儿1例,新生儿6例,婴儿4例,儿童6例,成人4例)成骨不全的临床及X线平片观察。
短句来源
    Results The proof through induced labor and postpartum as followed:2 cases of osteogenesis inperfecta,3 cases of achondrogenesis,1case of suspicious congenital bone syphilis,1case of pointed cranial deformity,1case of arm phalanx,3 cases of upper digestive system atresiaand 4 negative cases.
    结果:经引产及产后证实,成骨不全2例,软骨发育不全3例,可疑骨梅毒1例,上肢缺如1例,尖头畸形1例,上消化道闭锁3例,阴性4例。
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  osteogenesis
Visualization of vascular ultrastructure during osteogenesis by tissue engineering technique
      
The aim of this paper was to observe and visualize the changes in osteoblasts by electron microscopy during osteogenesis using tissue engineering technique.
      
Upon long-term culturing, the mesenchymal stromal cells have proved to lose their potential for adipogenic differentiation but preserve the potential for osteogenesis.
      
Increased levels of osteogenesis and resorption markers were detected in the blood of the cosmonauts in the early rehabilitation period after a spaceflight.
      
Chondrogenesis and Osteogenesis in Ectopic Transplants of the Fetal Liver in Mice
      
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Four different kinds of bone graft were implanted in right or left defective radius of rabbits:perforated decalcified bone matrix(PDBM),non-perforated decalcified bone matrix(NPDBM),perforated stirface-decalcified bone(PSDB)and non-perforated surface-decalcified bone(NPSDB).After implantation, the rabbits were killed at 2,4,8 and 12 weeks respectively,and studied by radionuclide bone imaging,then compared by radiological and histological examinations.The results showed that perforations on bone may enhance the...

Four different kinds of bone graft were implanted in right or left defective radius of rabbits:perforated decalcified bone matrix(PDBM),non-perforated decalcified bone matrix(NPDBM),perforated stirface-decalcified bone(PSDB)and non-perforated surface-decalcified bone(NPSDB).After implantation, the rabbits were killed at 2,4,8 and 12 weeks respectively,and studied by radionuclide bone imaging,then compared by radiological and histological examinations.The results showed that perforations on bone may enhance the incorporation between graff and host bone and the new bone formation. SDB has the same osteogenesis induction effect as DBM.It was concluded that 99mTc-MDP bone imaging was an effective and first chosen method for the early diagnosis of viability in bone allograft.

人工造成家兔桡骨缺损后植入同种异体的微孔和无微孔脱钙骨基质(PDBM、NPDBM)及微孔和无微孔表面脱钙骨(PSDB、NPSDB)等四种骨组织,手术后2、4、8、12周进行99mTc-MDP骨显像,并与X线平片及组织学变化相比较。结果表明,微孔制备有利于植入骨的新骨形成,加速植入材料的新骨替代;SDB具有与DBM相似的诱导成骨作用;核素骨显像对早期判断异体移植骨的成活情况是一种有效而首选的方法。

Objective: To elucidate the origin of cells and the molecular mechanism of periosteal osteogenesis. Methods: Complexes of recombinant human bone morphogenetic protein 2 (rhBMP 2)/ceramic bovine bone (CBB) and transforming growth factor β (TGF β)/CBB were implanted into the muscle pouches of mice. The histological reactions were observed at the intervals of 3, 5, 7, 14 and 21 days post implantation. The thickness of the 14th day newly formed bone was also measured. Results: The average thickness of...

Objective: To elucidate the origin of cells and the molecular mechanism of periosteal osteogenesis. Methods: Complexes of recombinant human bone morphogenetic protein 2 (rhBMP 2)/ceramic bovine bone (CBB) and transforming growth factor β (TGF β)/CBB were implanted into the muscle pouches of mice. The histological reactions were observed at the intervals of 3, 5, 7, 14 and 21 days post implantation. The thickness of the 14th day newly formed bone was also measured. Results: The average thickness of the newly formed bone displayed no significant difference between TGF β and rhBMP 2 group ( P >0.05). The aggregation and proliferation of undifferentiated mesenchymal cells in the periosteum were observed 5 d after implantation of rhBMP 2/CBB. By day 7, new cartilage formation was demonstrated. On 7 d after implantation of TGF β/CBB, cartilage and intramembranous bone formation was seen in the periosteum. By day 14, both of them showed active periosteal bone formation. Newly formed bone trabeculae increased and osteoblasts were around them. By day 21, newly formed bone became more mature and connected with the thigh bone. Conclusion: Both BMP and TGF β are diffusible in vivo and are capable of stimulating periosteal osteogenesis. The target cells in the periosteum are different between BMP and TGF β. BMP can induce undifferentiated cells in the medium layer of the periosteum to differentiate into osteoblasts and chondroblasts, while TGF β stimulates the proliferation as well as the activity of osteoprogenitor cells and osteoblasts in the inner layer of the periosteum.

目的:探讨骨膜成骨的细胞来源及分子机制.方法:将转化生长因子-β(TGF-β)和重组人骨形成蛋白-2(rhBMP-2)分别与陶瓷化牛骨(CBB)复合后,种植于小鼠股骨附近的肌肉间隙内.植入后3,5,7,14,21d取材,光镜观察股骨的组织学变化并测量第14日标本的股骨厚度.结果:植入rhBMP-2/CBB后第5日,骨膜内未分化间充质细胞聚集增生,第7日可见软骨生成.植入TGF-β/CBB第7日,骨膜内见大量软骨及膜内骨形成.第14日,上述两种植入物骨膜内均见新骨形成活跃,新生骨小梁增多,其周围有成骨细胞.第21日,骨膜内的新生骨均趋向成熟并与宿主股骨相连.新生骨的厚度二组间无显著性差异(P>0.05).结论:骨形成蛋白和TGF-β在体内均具有扩散作用并可刺激骨膜成骨.二者在骨膜内的靶细胞不同.骨形成蛋白诱导骨膜中间层的未分化间充质细胞向骨细胞系分化;TGF-β刺激骨膜深层的骨祖母细胞、成骨细胞等的增殖和功能活跃.

In order to observe the properties of the domestic hydroxyapatite (HA) in vivo and the effect of fixation to prosthesis under loading , the authors implanted domestic HA coated hip implants into 20 adult dogs, which were then divided into 5 groups and each group was sacrificed at 3, 6, 12, 24 and 40 weeks after surgery . Histomorphological studies were carried out with light , scanning electron , fluoresence and polarized light microscopes . No degradation was found in...

In order to observe the properties of the domestic hydroxyapatite (HA) in vivo and the effect of fixation to prosthesis under loading , the authors implanted domestic HA coated hip implants into 20 adult dogs, which were then divided into 5 groups and each group was sacrificed at 3, 6, 12, 24 and 40 weeks after surgery . Histomorphological studies were carried out with light , scanning electron , fluoresence and polarized light microscopes . No degradation was found in the sintered HA coating after surgery . The integration of the interface between HA coating and Ti substrate was solid and the sintered HA coating of the implant formed tight bonding with the surrounding bony tissue in the specimens of different follow-up periods .The apposition of new bone formation on HA surface was most prominent at the anterior and medial aspects of the implant . Histologically, the HA surface was covered by fibrous membrane which was most prominent at the posterior and lateral aspects of the implant. The extent of osteogenesis and the formation of fibrous membrance over the HA surface was different at different follow-up periods .The average coverage of the HA surface by the bony tissue and the fibrous membrane was 66.44%~78% and 16.22~18.54% respectively. No ectopic bone formation was seen on the HA surface . There was no cortical atrophy of the femoral shaft nor bone radiolucent line except in one implant with broken HA coating.Subcortical cancellous bone formation(SCBF) between the implant and the femoral cortex was seen in different degrees in the follow-up period and the incidence of SCBF was 100% at the Gruen zone 4 . The shear strength of the implace increased gradually within 24 weeks after the operation, with a range of 33. 09 MPa to 0.28 MPa . The result of this study strongly demonstrated that the domestric HA material as a coating of the implant could fix the prosthesis effectively .

本实验以国产HA涂层烧结的犬用人工股骨柄为研究对象,将行关节置换后的20只成年犬,按术后3、6、12、24、40周平均分成5个组,全面观察HA涂层在体内的性能和在负重情况下对假体的固定效果。综合运用了普通光镜、偏振光显微镜、扫描电镜、荧光显微镜来进行组织学观察,发现术后各期HA涂层都无明显降解,HA周围无炎性细胞,HA涂层与钛基底的结合基本良好,HA外都有骨组织与之紧密结合,并且HA表面的成骨多集中在股骨的前侧、内侧。HA表面的部分区域被纤维组织覆盖,且多见于股骨的后侧、外侧。组织计量分析示:术后各期HA表面骨及纤维膜的占有率分别在66.44%~78%及16.22%~18.58%之间。影像学示:所有术侧股骨都未见异位骨化、骨皮质反应、骨外膜反应和骨反应线,假体周围都未见透亮线(1例HA层有碎裂的假体除外)。所有假体周围都有不同程度的皮质骨下新生骨形成。力学测试示:假体上、中、下3段的剪切强度随植入时间的增加而增大,最大剪切强度为33.09MPa,最小剪切强度为0.28MPa。本实验表明,用国产HA涂层来固定人工股骨柄是切实可行的。

 
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