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   lamivudine 在 消化系统疾病 分类中 的翻译结果: 查询用时:0.187秒
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lamivudine
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  拉米夫定
    1. The Experimental Study of rALR on Immunologic Response Induced by Exogenous Antigen in Rat 2. Analysis on Cause of Death in 115 Patients with Hepatic Failure Induced by Viral Hepatitis 3. The Primary Clinical Study of Peginterferon Alfa-2a in the Treatment the Patients with HBeAg-Positive Chronic Hepatitis B and with Drug Fast to Lamivudine
    1.肝再生增强因子对外原性抗原引起机体免疫应答影响的初步研究 2.病毒性肝炎肝衰竭患者死亡原因分析 3.聚乙二醇化干扰素α-2a治疗HBeAg阳性的慢性乙型肝炎及其应用于拉米夫定耐药的初步临床观察
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    1.Clinic Study on the Adefovir Dipivoxil Treat Patients with HBeAg(+) Hepatitis B Resistant to Lamivudine 2.Preliminary Study on the Effect of Severe Hepatitis Plasma on Umbilical Cord Blood Mesenchymal Stem Cells in Vitro
    1.阿德福韦酯治疗拉米夫定耐药HBeAg(+)慢性乙肝的临床研究 2.重型肝炎患者血浆对体外培养脐血间充质干细胞影响的初步研究
短句来源
    However,22.8% of patients in the control group had YMDD variant HBV as compared with 3.03% in the treated group,and P value was <0.05.Conclusion:Thymosin-α1 combined with Lamivudine is effective for the patients with chronic hepatitis B and is valuable to be used in clinical.
    HBV YMDD变异株:治疗组仅有1例(3.03%),对照组有8例(22.8%),两组比较,差异有统计学意义(P<0.05)。 结论:拉米夫定联合胸腺肽α1治疗慢性乙型肝炎疗效较好,值得临床应用。
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    METHODS 360 patients with lamivudine was measured by gene-chip,ELISA and autobiological analyzer.
    方法利用基因芯片、ELISA及生化检测技术检测360例慢性乙肝患者服用拉米夫定4~24个月后YMDD变异、HBV-DNA及ALT水平变化。
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    The dosage in the entecavir group and lamivudine group was 0.5 mg/d and 100 mg/d, respectively, and the duration of therapy was 48~96 weeks.
    恩替卡韦组与拉米夫定组的剂量分别为0.5mg/d和100mg/d。 疗程为48~96周。
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  “lamivudine”译为未确定词的双语例句
    Methods The serum YMDD mutation,HBV DNA,ALT and HbeAg levels of 60 patients on lamivudine therapy were detected by FQ-PCR,ELISA,and rate method,respectively.
    方法采用实时荧光定量PCR、ELISA及速率法分别检测60例乙肝患者经拉米呋啶治疗后其血清YMDD、HBV DNA、乙肝标志物及ALT的变化情况。
短句来源
    Results The occurrence of mutation in the patients was 3.3% and 13.3%,respectively after 9-month and one-year treatment with lamivudine.
    结果拉米呋啶治疗9月、1年后YMDD的变异率分别为5%、13.3%。
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    In the meantime,the patients received Tα1 plus lamivudine had less than those YMDD mutant received lamivudine monotherapy [8.3 percent vs.33.3 percent(P<0.05) and 16.7percent vs.52.4 percent(P<0.05),respectively].
    LAM组分别为14.3%,23.8%,38.1%和52.4%(P<0.05;P<0.01)。
短句来源
    45.8 percent of patients receiving Tα1 plus lamivudine achieved complete response,as compared with 9.5 percent in the group receiving lamivudine alone at the first year,and the sustained response rates were 58.3% and 41.7% vs.28.6% and 14.3%,respectively(P<0.01).
    治疗1、2和3年后LAM+Tα1组的完全应答率分别为45.8%,58.3%和41.7%明显高于LAM组的9.5%,28.6%和14.3%(P<0.05;P<0.01);
短句来源
    Results IFN-γ level in patients with CHB before lamivudine treatment was significantly decreased (P<0.01) and IL-6 level increased as compared with the normal control group; IFN-γ level in pre-treatment were 139.98 ±112.61 pg/ml and in control 286.31 ±180.25 pg/ml ( P< 0.01 );
    结果治疗前CHB患者IFN-γ为139.98±112.61pg/ml,对照组286.31±180.25pg/ml(P<0.01);
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  lamivudine
Rapid titrimetric and spectrophotometric assay methods for the determination of lamivudine in pharmaceuticals using iodate and t
      
In titrimetry, an aqueous solution of lamivudine is titrated directly with iodate in an acidic medium, and in the presence of an excess of bromide using methyl orange as an indicator.
      
In all methods, the amount of iodate which reacted corresponds to the amount of lamivudine content.
      
The methods were successfully applied to the assay of lamivudine in tablet form and the results were compared with those of a reference method by applying the Student's t-test and F-test.
      
Disease progression to AIDS was associated with ?4 and ?2, most evident for zidovudine-lamivudine regimens without a protease inhibitor (P = 0.03); and, 3.
      
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The curative effect of interferon alpha plus lamivudine for

采用重组干扰素α联合拉米夫定治疗慢性乙型肝炎(下简称慢乙肝)患者31例(A组),并与31例仅行保肝和对症治疗的慢乙肝患者(B组)进行疗效比较。结果显示,两组临床、生化指标均获改善;A组HBeAg阴转率为65.5%,B组仅10.7%,两组比较差异显著(P<0.01);A组HBV-DNA均转阴,而B组无1例阴转。认为干扰素α联合拉米夫定治疗慢乙肝可改善患者的肝功、稳定病情,提高e抗原阴转率。

The efficacy and safety of new nucleotide analogues lamivudine and famciclovir were studied in the patients with chronic hepatitis B and the patients receiving liver transplant. The results showed that the two drugs could rapidly decrease HBV DNA levels in the serum from the patients with chronic hepatitis B and prevent the recurrence of hepatitis B in some of the liver transplanted patients. Normalization of aminotransferases and histological improvement in most of patients could also be demonstrated....

The efficacy and safety of new nucleotide analogues lamivudine and famciclovir were studied in the patients with chronic hepatitis B and the patients receiving liver transplant. The results showed that the two drugs could rapidly decrease HBV DNA levels in the serum from the patients with chronic hepatitis B and prevent the recurrence of hepatitis B in some of the liver transplanted patients. Normalization of aminotransferases and histological improvement in most of patients could also be demonstrated. However, when there was genetic mutation of the virus in the bodies of the patients or the drug treatment was stopped, the hepatitis would recur in some of the patients.

新药拉咪呋啶和法昔洛韦是治疗慢性乙型肝炎的新型核苷类似物。口服拉咪呋啶或法昔洛韦可使大多数患者血清转氨酶恢复正常及组织学病变明显改善,还可迅速降低血清HBVDNA水平及阻止肝炎、肝移植患者肝炎复发。但已注意到病毒变异的出现和停止治疗后可使肝炎复发

Clinical effects of the treatment for chronic hepatitis B with lamivudine were observed and compared with the effects with virazole. The result showed that daily dose of lamivudine could restrict the replication of HBV obviously, with HBV-DNA and BHeAg turning negative and ALT declining. The curative effect of lamivudine was better than that of virazole

笔者观察了拉米夫定治疗慢性乙型肝炎的临床疗效,并与病毒唑进行对照比较.结果表明,口服拉米夫定100mg/d,可明显抑制乙型肝炎病毒的复制,表现为HBV-DNA、HBeAg转阴及ALT下降,疗效明显优于病毒唑.

 
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