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fast cyclic voltammetry
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  快速周期伏安法
     Fast cyclic voltammetry (FCV) was used to investigate the effects of marine acidic oligose HSH971 on dopamine (DA) release from striatum (Str) and amygdala (Amy) in 6-hydroxydopamine (6-OHDA) induced rat models of Parkinson's disease (PD).
     采用快速周期伏安法(FCV),在以6-羟基多巴胺(6-OHDA)制备的帕金森病(PD)模型大鼠上检测褐藻酸性寡糖HSH971对纹状体(Str)、杏仁核(Amy)多巴胺(DA)释放的影响。
短句来源
     Group 3( n =9) ,40 μg FeCl 3. Three weeks after the intranigral injection of FeCl 3, DA release was measured by fast cyclic voltammetry and DA contents by high performance lipid chromotophotography (HPLC).
     9只大鼠左侧SN内注射FeCl3溶液 4 0 μg(Ⅲ组 ) ,3周后采用快速周期伏安法 (FCV)监测纹状体DA的释放量 ,高效液相色谱法 (HPLC)检测纹状体DA含量。
短句来源
     In vivo fast cyclic voltammetry (FCV) was used to investigate dopamine (DA) release fromamygdala (Amy) of female rats in different phases of estrus cycle, ovaricectomized (OVX) rats and malerats. Tyrosine hydroxylase (TH) immunohistochemistry was employed to measure the numbers of immunore-active neurons in ventral tegmental area (VTA) of midbrain in the rats.
     用快速周期伏安法(fast cyclic voltammetry,FCV)测定了动情周期各期雌鼠、去卵巢(ovaricectomized,OVX)鼠和正常雄鼠的杏仁核(amygdala,Amy)多巴胺(dopamine,DA)释放,同时应用酪氨酸羟化酶(tyrosine hydrox-ylase,TH)免疫组化技术检测了以上各组大鼠腹侧背盖区(ventral tegmental area,VTA)的TH阳性神经元数目。
短句来源
     In the present study, using fast cyclic voltammetry (FCV), atomic absorption/flame emission spectrophotometry and immunohistochemistry, we investigated the correlation between iron levels and degeneration of dopaminergic neurons in rat nigrostriatal system during the early 6-OHDA lesions in the medial forebrain bundle (MFB).
     应用快速周期伏安法(fast cyclic voltammetry,FCV)、原子吸收分光光度法及免疫组织化学方法,观察了6-羟基多巴胺(6-hydroxydopamine,6-OHDA)单侧损毁大鼠内侧前脑束(medial forebrain bundle,MFB)早期黑质(substantia nigra,sN)铁水平与多巴胺(dopamine,DA)神经元损伤的变化,以及纹状体(striatum,Str)的DA释放。
短句来源
     \ Methods\ With fast cyclic voltammetry (FCV), the effects of estrogen on DA release as well as the influence of estrogen on rotational behavior in 6 hydroxydopamine (6 OHDA) induced PD model rats were investigated.
     ②方法 采用快速周期伏安法 (FCV) ,在以 6 羟基多巴胺 (6 OHDA)制备的PD模型大鼠身上 ,检测去卵巢(OVX)与苯甲酸雌二醇 (EB)处理对电刺激诱发的CAN区DA释放量的影响 ,同时观察雌激素对PD模型鼠行为的影响。
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  快速循环伏安法
     Fast Cyclic Voltammetry and Its Recent Developments
     快速循环伏安法及其近期发展
短句来源
     MONITORING DOPAMINE RELEASE OF RATS USING FAST CYCLIC VOLTAMMETRY(FCV) IN VIVO
     快速循环伏安法(FCV)在体测定大鼠多巴胺释放
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  “fast cyclic voltammetry”译为未确定词的双语例句
     Methods In vivo fast cyclic voltammetry was used to measure DA release from male and female rats CeA.
     ②方法用快速周期伏安测定法,测定了电刺激腹侧背盖区(VTA)引起的不同性别动物CeA的DA释放量。
短句来源
     The numerical simulation method for fast cyclic voltammetry (FCV) was modified by Glalgorithm to raise its computation speed.
     采用Gl算法改进了快扫伏安曲线的数值模拟,提高了模拟计算的速度.
短句来源
     METHODS:Twenty four rats were equally divided to receive budipine in a dose of 30 mg/kg by intraperitoneal injection,equal volume of 0.1 mol/L phosphate buffer (solvent for 10% cremophor)or equal volume of 10% cremophor(solvent for budipine)and the dopamine overflow evoked by electrical stimulation in unilateral CPu in each group was measured by fast cyclic voltammetry(FCV).
     方法:24只大鼠等分3组,分别ip30mg/kg布地品以及等容量的0.1mol/L磷酸缓冲液(为cremophor的溶剂)和10%cremophor(为布地品的溶剂)。 采用快速循环伏安计测定法(FCV)测定注射药物及对照剂后电刺激MFB引起同侧CPu内多巴胺释放量的变化。
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  fast cyclic voltammetry
Fast cyclic voltammetry measurements in the dorsal raphe nucleus demonstrated significant decreases in electrically evoked 5-HT efflux in lpa1(-/-) mice.
      
Dopamine (DA) release in the nucleus accumbens (NAc) and caudate putamen (CPu) was measured in vivo using fast cyclic voltammetry, following electrical stimulation of the medial forebrain bundle.
      
Catecholamine release from single chromaffin cells was measured by means of fast cyclic voltammetry.
      
Release of endogenous dopamine was measured by fast cyclic voltammetry as the increase in the extracellular concentration of dopamine elicited by electrical stimulation.
      
Release of endogenous dopamine elicited in slices of rat neostriatum or nucleus accumbens by a single electric pulse or by trains of 4 or 10 pulses was examined using fast cyclic voltammetry.
      
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Objective To investigate the relationship between sex and dopamine(DA) release from central amygdaloid nucleus evoked by electric stimulation in rats. Methods In vivo fast cyclic voltammetry was used to measure DA release from male and female rats CeA. Results DA release in male and female rats was dependent upon the stimulation intensity, number of pulses and frequencies. With the same stimulation parameters, DA release from female rats was significantly higher than from male rats. Conclusion ...

Objective To investigate the relationship between sex and dopamine(DA) release from central amygdaloid nucleus evoked by electric stimulation in rats. Methods In vivo fast cyclic voltammetry was used to measure DA release from male and female rats CeA. Results DA release in male and female rats was dependent upon the stimulation intensity, number of pulses and frequencies. With the same stimulation parameters, DA release from female rats was significantly higher than from male rats. Conclusion There is an input/output relation between DA release and electric stimulation parameters. And DA release was partly regulated by estrogen.

①目的探讨电刺激诱发的大鼠中央杏仁核(CeA)多巴胺(DA)释放量与性别的关系。②方法用快速周期伏安测定法,测定了电刺激腹侧背盖区(VTA)引起的不同性别动物CeA的DA释放量。③结果雌鼠和雄鼠CeA的DA释放量均具有刺激强度、刺激脉冲和刺激频率依赖关系;在相同刺激条件下,雌性大鼠DA释放量明显高于雄性。④结论大鼠CeA的DA释放量与电刺激参数有量效关系,而且部分受雌激素的控制。

Objective To study the effects of haloperidol(HAL) on electric stimulated dopamine(DA) release from rat nucleus accumbens(Acb). Methods The rats was divided into low dosage(0. 5mg/kg/d) and high dosage(1.0mg/kg/d) of HAL treated groups and control group. Fast cyclic voltammetry was used to check the changes of DA release from Acb after HAL challenge. Results After continuous oral administration of high and low dosages of HAL, the DA release from Acb was significantly decreased( t=7.59; 24.66,P ...

Objective To study the effects of haloperidol(HAL) on electric stimulated dopamine(DA) release from rat nucleus accumbens(Acb). Methods The rats was divided into low dosage(0. 5mg/kg/d) and high dosage(1.0mg/kg/d) of HAL treated groups and control group. Fast cyclic voltammetry was used to check the changes of DA release from Acb after HAL challenge. Results After continuous oral administration of high and low dosages of HAL, the DA release from Acb was significantly decreased( t=7.59; 24.66,P <0.001). After abdominal injection of HAL, the DA release from Acb in the control group was significantly increased( t=8.15 ̄90.76,P <0.001), while in the HAL treated groups, the changes of DA release were not obvious and the difference of DA release between the HAL treated groups and the control group was significant( t=32.41 ̄115.23,P< 0.001). Conclusion The results suggest that HAL challenge can increase DA release from Acb, while continuous administration of HAL can inhibit DA release.

①目的研究氟哌啶醇(HAL)对大鼠伏核多巴胺(DA)释放的影响。②方法用快速周期伏安法,检测了小剂量(0.5mg·kg-1·d-1),大剂量(1.0mg·kg-1·d-1)HAL给药组和对照组大鼠连续口服或腹腔注射HAL前后伏核DA释放量的改变。③结果在连续21d口服0.5mg·kg-1·d-1和1.0mg·kg-1·d-1HAL的大鼠,其伏核的DA释放量与对照组相比明显减少,差异有显著性(t=7.59,24.66,P均<0.001);腹腔注射HAL激发后,对照组DA释放量较注射前明显增加(t=8.15~90.76,P均<0.001);两给药组DA释放量与注射前相比则变化较小;但与对照组相比,差异有显著性(t=32.41~115.23,P均<0.001)。④结论HAL小剂量腹腔注射可增加伏核的DA释放量,连续口服HAL则可抑制伏核DA释放量。

Objective The Present study investigates that elecrical stimulation of the rat median forebrain bundle (MFB) results in frequency-dependent dopandne (DA) release within th6 ipsilateral caudate putamen (CPu) and nucleus accumbens (ACb).Methods In vivo fast cyclic voltammetry (FCV) with carbon fiber microelectrodes was used to monitor the ds of stimulation frequen cy on DA release from CPu and ACb.The results were analysed statishcally.Results When stimulating Parameters within 340 A. o.5rns square-wave,...

Objective The Present study investigates that elecrical stimulation of the rat median forebrain bundle (MFB) results in frequency-dependent dopandne (DA) release within th6 ipsilateral caudate putamen (CPu) and nucleus accumbens (ACb).Methods In vivo fast cyclic voltammetry (FCV) with carbon fiber microelectrodes was used to monitor the ds of stimulation frequen cy on DA release from CPu and ACb.The results were analysed statishcally.Results When stimulating Parameters within 340 A. o.5rns square-wave, at 100 pulse, significant differnces in stimulated DA release were observed between the frequencthe used in the CPu and ACb. And both DA rehase was dependent on the stimulation frequency. The maximum release from ACb and CPu were evoked by 80 Hz and 100Hz respectively.Conclusion Electrhal stimulatinn of MFB evoked DA release from CPu and ACb were dependent on stimulation frequency and results in simila:" bellrshaped' curves.

目的研究电刺激前脑内侧束引起纹状体和伏位多巴胺释放量与刺激频率的关系.方法应用快速周期伏安法,以碳纤维微电极直接在体研究刺激频率对大鼠纹状体和伏核多巴胶释放的影响,双因素方差分析统计学处理结果。结果应用0.5ms、340μA、100个脉冲的方波电刺激时,纹状体和伏核的多巴胺释放量明显不同,并取决于所应用的刺激频率.当刺激频率为80Hz和100Hz时,分别引起伏核和纹状体的多巴胺释放量达到最大.结论电刺激前脑内侧束(MFB)引起纹状体(CPu)和伏核(ACh)的多巴胺(DA)释放取决于刺激频率。

 
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