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multiple malformations
相关语句
  多发性畸形
     ANENCEPHALY AND MULTIPLE MALFORMATIONS
     无脑儿与多发性畸形
短句来源
     143 cases of anencephalies were investigated . 88 cases of them combined with multiple malformations (61.54%).
     本文观察了143例无脑儿,有88例合并多发性畸形,占61.54%,男女之比为1:2.1.合并二脏器以上畸形者有47例;
短句来源
     VACTERL ASSOCIATION - ONE OF THE NEONATES MULTIPLE MALFORMATIONS WHICH MAINLY CHARACTERIZED BY ESOPHAGEAL ATRE- SIA
     VACTERL综合征—一种以食道闭锁为主要特征的新生儿多发性畸形
短句来源
  多发畸形
     The top five most common diagnoses were uro- logical anomalies(18.5%),brain anomalies(15.2%),multiple malformations(10.6%),infections (9.9%)arid congenital heart disease(8.1%).
     胎儿会诊疾病中占据前5名的为泌尿系异常73例(18.5%)、脑部异常包括脑室扩张和脉络膜囊肿60例(15.2%)、多发畸形42例(10.6%)、宫内感染包括宫内发育迟缓39例(9.9%)和心脏畸形32例(8.1%)。
短句来源
     Microdeletion of 22q11 was found in 2 cases with Tetralogy of Fallot(TOF) accompanied by multiple malformations.
     2例法鲁氏四联症伴心外多发畸形患者,有22q11缺失。
短句来源
     0. Congenital multiple malformations (with or without mental retardation), 24 cases, of which 14 were of unknown etiology with significant increase in aneuploids, (the mean value being 11.5%). And there was one case of Fanconi's anemia with high chromosomal aberration rate (25%).
     3.先天多发畸形或伴智力障碍:24例,其中病因不明的14例,患儿非整倍体细胞增加,平均值为11.5%。
短句来源
     Results In the four cases,3 cases underwent one stage perineal anoplasty with low IA after birth and then presented abdominal distend and constipation,two with anus stenosis,another one with high IA and multiple malformations underwent pull-through procedure for anoplasty.
     结果  4例患儿中 3例为低位IA ,一期经会阴肛门成形术后出现腹胀、便秘 ,2例存在肛门狭窄 ,另 1例为高位IA并多发畸形
短句来源
  “multiple malformations”译为未确定词的双语例句
     The 5p deletion syndromes are further divided into 8 types according to the presence or absence of 4 main clinical symptoms, namely, cat-like cry, facial features, mental retardation, and multiple malformations.
     其次,根据5p缺失综合征四个主要临床症状,即似猫叫哭声、典型面部特征、智力低下、以及不同的畸形来剖析5p缺失综合征,将5p缺失综合征患者按表型分为8类,并确定了这8类患者在5号染色体短臂上相应的缺失区域。
短句来源
     A phenotype map of 5p was constructed. Region 5pl2-5p13.32 is responsible for severe mental retardation and multiple malformations;
     依据此细胞遗传图,制作了5p表型图:5p12-5p13.32是严重智力低下及不同的畸形的相关区域;
短句来源
     Among them, four were associated with multiple malformations. In TORCH infection detection, there were five cytomegalovirus (CMV) -DNA positive, two rubella virus (RV) -RNA positive, two toxoplasma (TOX)-DNA positive and two herpes simplex virus (HSV)-DNA positive.
     ②胎儿脐血检测发现巨细胞病毒 (cytomegalovirus ,CMV)感染 5例 ,风疹病毒 (rubellavirus ,RV)感染 2例 ,弓形体 (toxoplasma ,TOX)感染 2例 ,单纯疱疹病毒 (herpessimplexvirus ,HSV)感染 2例 ,宫内TORCH感染发生率为 1 9.6 4 %。
短句来源
     According to the results of ultrasound,MRI and karyotyping,the diagnosis was holoprosencephaly in 3 cases (chromosome aberration of 18 in 2 cases),hydrocephaly in 4 cases (complicated with multiple malformations in 2 cases),enlargement of the cisterna magna in 4 cases (classic Dandy-Walker syndrome in 1 case,complicated with cardiac anomaly in 2 cases,normal development upto 1 year after birth in 1 case),midline cyst in 2 cases,shift of the midline by unilateral intracerebral hemorrhage in 1 case.
     脑积水4例,其中2例合并其他异常; 小脑延髓池增宽4例,其中1例为经典型Dandy-Walker综合征,2例合并心脏异常,1例随访至1岁未见异常;
短句来源
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  multiple malformations
The mothers of children with hydrocephalus and multiple malformations had used oral contraceptives during the first trimester of pregnancy more often than the mothers of the controls.
      
Forty-three (44.8%) of the cases had hydrocephalus without other malformations (isolated hydrocephalus), 18 (18.7%) infants had recognized chromosomal or non-chromosomal syndromes and 35 children (36.4%) had multiple malformations.
      
In one patient epilepsy was combined with multiple malformations (normal dwarfism, prematurely old face, skeletal abnormalities) and oligophrenia.
      
Of five additionally tested retinoids, all induced multiple malformations.
      
Of the 1.07% of malformed children, 0.90% had single and 0.17% had multiple malformations.
      
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A cytogenetical study was made on 162 cases of children with congenital malformations and/or mental retardation. Among them there were 32 cases of congenital multiple malformations with mental retardation and dermatoglyphical anomalies, of which there were 27 cases, all being trisomy-21 syndrome, which were shown to have chromosomal aberrations, accounting for 84.4%. Consequently these 8 signs oould be used in combination as a screening test for autosomal disorders.According to clinical features, these...

A cytogenetical study was made on 162 cases of children with congenital malformations and/or mental retardation. Among them there were 32 cases of congenital multiple malformations with mental retardation and dermatoglyphical anomalies, of which there were 27 cases, all being trisomy-21 syndrome, which were shown to have chromosomal aberrations, accounting for 84.4%. Consequently these 8 signs oould be used in combination as a screening test for autosomal disorders.According to clinical features, these 162 cases were divided into 4 groups: A. Trisomy-21 syndrome, 53 cases. Among them, there were 30 cases (56.6%) with karyotype of 47, +21, 20 cases (37.7%) of mosaic type 46/47, +21, and 3 cases (5.7%) with translocation of D; 21 or G; 21. Males predominated in all types. The frequency of the first two types increased with increasing maternal age. B. Disorders of sexual differentiation 44 cases, including 1. Pseudohermaphroditism, 21 cases, the sexual chromosomes being in accordance with their sexual glands. 2. True hermaph-roditism, 5 cases, of which 2 were with 46, XX/46, XY, 2 with 46, XX and 1 with45, X, -Y; -9, +t(Yq; 9p). 3. Gonadal dysgenesis, 5 cases, of which 3 were with 45, X/46, XX, 1 with 45, X/46, XX/47, XXX and 1 with 46, XY/45, X. 4. Congenital testi-cular dysgenesis, 13 cases, of which 2 were with 46 XX/46, XY and the others with46, XY in Karyotype. 0. Congenital multiple malformations (with or without mental retardation), 24 cases, of which 14 were of unknown etiology with significant increase in aneuploids, (the mean value being 11.5%). And there was one case of Fanconi's anemia with high chromosomal aberration rate (25%). D. Mental retardation (with or without single malformation), 41 cases, all of which were cytogenetioally normal.

本文为162例先天畸形和智力障碍儿的染色体观察,发现具有先天多发畸形、智力障碍和肤纹异常者,染色体异常占84.4%,故可以此作为常染色体病的筛选指征。本组病例根据临床可分为4类:1.21三体综合征:53例,其中标准型(47,+21)占56.6%,嵌合型(46/47,+21)占37.7%,易位型(21;D和21;G)占5.7%。2.性分化异常:44例,约半数为假两性畸形,性染色体与性腺相符;真两性畸形5例,核型各为46,XX/46,XY(2例),46,XX(2例)和45,X,-Y,-9,+t(Yq;9p)(1例)。性腺发育不全症5例,核型为45,X/46,XX(3例),45,X/46,XY和45,X/46J XX/47,XXX各1例,均为嵌合型Turner综合征。先天性睾丸发育不全13例,核型多数为46,XY,仅2例为46,XX/46,XY。3.先天多发畸形或伴智力障碍:24例,其中病因不明的14例,患儿非整倍体细胞增加,平均值为11.5%。4.智力障碍儿或伴单发畸形41例,染色体均正常。

Between sept 1985,and Dec 1986,the kinds and incidence of birth defecls in 7709 perinatal infants in Guangzhou were analysed.There were 88 cases of congenital deformity,in which single malformation 59 cases (67%);multiple malformation 29 cases (33%).The malformation incidence was 11.4‰.The defects involved 109 parts (14.14‰).Facial region 4.15‰;muscular and skeletal system2.59‰; urogenital systeml.56‰;central nervous systeml.29‰;and cases hydrops fetalis (1.29‰).The incidence of malformation...

Between sept 1985,and Dec 1986,the kinds and incidence of birth defecls in 7709 perinatal infants in Guangzhou were analysed.There were 88 cases of congenital deformity,in which single malformation 59 cases (67%);multiple malformation 29 cases (33%).The malformation incidence was 11.4‰.The defects involved 109 parts (14.14‰).Facial region 4.15‰;muscular and skeletal system2.59‰; urogenital systeml.56‰;central nervous systeml.29‰;and cases hydrops fetalis (1.29‰).The incidence of malformation inside the city was 10.28‰;in the suburb 21‰.Statistically,the difference is significant (P<0.05).The malformation incidence was 350‰ in dead infants in perinatal stage;while it was 6.13‰ in term live birth.During the 16 months the incidences varied from 4.96‰ to 22.72‰ monthly.

广州市四所医院连续16个月出生的7709例围产儿中共检出88例畸形儿,其中单一畸形59例(67%);多发畸形29例(33%)。按病例统计的发生率为11.42‰;按畸形累及部位统计则总畸形部位为109例次,发生率为14.14‰,各系统的发生率为:领面部4.15‰;肌肉骨骼系统2.59‰;必尿生殖系统1.56‰;中枢神经系统1.29‰;消化系统1.04‰;心血管系统0.91‰;其它畸形中以水肿儿为多,共10例(1.59‰)。城区的发生率为10.28‰;郊区为21‰。经统计学处理城郊之间差异显著(P<0.05)。围产期死亡婴中的发生率为350‰,足月活婴中的发生率为6.13‰,16个月中的最低一个月发生率为4.96‰,最高一个月为22.72‰。

From October 1st, 1986 to September 30 rd, 1987, 44 238 newborns sampled from obstetrical departments of 30 hospitals of Hubei Province were investigated. Of them 411 were those with defects, with an incidence of 9.29‰. The etiological factors contributing to inborn-defects were studied by paired matching. The results showed that the occurrence of inborn-defects was closely related to parity, gravida's catching of cold with fever, medication, exposure to toxic chemicals and noise, pregnancy complicated by internal...

From October 1st, 1986 to September 30 rd, 1987, 44 238 newborns sampled from obstetrical departments of 30 hospitals of Hubei Province were investigated. Of them 411 were those with defects, with an incidence of 9.29‰. The etiological factors contributing to inborn-defects were studied by paired matching. The results showed that the occurrence of inborn-defects was closely related to parity, gravida's catching of cold with fever, medication, exposure to toxic chemicals and noise, pregnancy complicated by internal diseases, etc., or co-existence of these factors at the first-trimester of pregnancy, and history of inborn-defect in family and heavy smoking of husbands before conception (P<0.01). 56.5% of the defects caused by long-term exposure to noise was multiple-malformation of muscular and skeletal system. The incidence of inborn-defect of newborn from mountain, hill and plain area was 14.58‰, 9.46‰ and 7.95‰ respectively.

1986年10月1日~1987年9月30日全省抽样调查30所医院,共分娩新生儿44238例,其中缺陷儿411例(9.29‰)。对其发病因素进行配对调查,结果出生缺陷的发生与产次,孕头3月内感冒发热、用药、接触化学毒物、噪音影响、合并内科疾病,多种因素协同作用,家族聚集及孕前男方大量吸烟等因素有密切关系(P<0.01)。长期噪音影响引起的缺陷儿中58.5%为肌肉、骨骼系统多发性畸形。居住山区、丘陵、平原的出生缺陷发生率分别为14.58‰、9.48‰及7.95‰。

 
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