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     Both T1+ (1.5 mmol /L) and Mn2+ (3mmol/L) could inhibit DAD and TA.
     TI~+(1.5mmol/L)及Mn~(2+)(3mmol/L)可抑制DAD及TA。
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     cell death genes comprehend P 35 ,P 53 ,RB,DCC,WT 1,CpGv,Bcr ab1,V erb A,tats20,DAD1,DAO 1/Fas,TGF β,RP 2,RP 8,TRPM 2,SGP 2,T1A,Bax,ICE,C rel,irrec rst and so on .
     与细胞死亡有关的基因包含 P35、P53、RB、DCC、WT- 1、Cp Gv、Bcr- abl、V- erb- A、tats2 0、DAD1、 ADO/Fas、 TGF-β、 TRP- 2、 RP- 8、TRPM- 2、SGP- 2、TIA、Bax、ICE、C- rel、irrec-rst等。
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     Methods Chromatographic column of YMC C18(150 mm×4.6 mm,5 μm)was used,mobile phase was methanol+0.02 mol/L NH4Ac=15+85(V/V),flowing rate was 1.0 ml/min,DAD detection wavelength was 210 nm.
     方法色谱柱为YMC C18(150mm×4.6mm,5μm),流动相为甲醇+0.02mol/LNH4AC=15+85(V/V),流量为1.0ml/min,二极管阵列检测器,检测波长为210nm。 结果该方法的线性范围为0.050~10.0μg/ml;
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     RESULTS: Perfused Phe 1 μmol·L-1 for 60 min, in the absence of Pro, Phe increased the amplitude of DAD from 7. 5±1. 2 to 9. 0±2. 0 mV (n= 8, P<0. 05), nonsignificantly changed the duration of DAD and induced TA in 3/11 preparations;
     结果:Phe 1 μmol·L~(-1)灌流60 min,无Pro时,使DAD幅值由7.5±1.2增加到9.0±2.0 mV(n=8,P<0.05),DAD时程变化不显著,3/11可诱发TA;
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     DAD scores in B group (12.80±1.47) was obvious higher than that of A (7.67±1.20) and D (8.83±1.17) groups (both P<0.01), but there was no difference compared with C group (11.50±1.87, P>0.05).
     肺组织病理DAD评分:B组为(12.80±1.47)分,明显高于A组(7.67±1.20)分和D组(8.83±1.17)分(P均<0.01),但与C组(11.50±1.87)分比较差异无显著性(P>0.05)。
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     My Dad
     我的爸爸
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     Game Dad
     游戏老爸
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  dad
In this paper, high performance liquid chromatography (HPLC) along with mass spectrometry (MS) and HPLC along with a diode array detector (DAD) was used to study the compound Ilex pubescens extract.
      
The liquid chromatograms obtained by DAD, total ion chromatograms (TIC) from positive-and negative-ion ESI-MS and the positive-and negative-ion APCI-MS were compared.
      
The liquid chromatograms obtained by TIC from ESI-MS provided more information on chromatographic peaks than those obtained by DAD or TIC from APCI-MS.
      
It is suggested that the fingerprints of the compound Ilex pubescens extract should be provided by the liquid chromatograms obtained by DAD together with TIC from the negative-ion ESI-MS.
      
The molecular weights of the nine main components in an HPLC-DAD chromatogram were determined by the corresponding positive-and negative-ion ESI and the positive-and negative-ion APCI mass spectra information.
      
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Gadolinium has been proposed for use as neutron poison for the control of criticality during the spent nuclear fuel dissolution, feed preparation, and solvent extraction.The distribution ratio of gadolinium (Dad) in system TBP-nitrate, concentration profiles of Gd in countercurrent extraction process with TBP and solubility of gadolinium nitrate in aqueous solution are presented. The effects of concentration of nitric acid, sodium nitrate, uranyl nitrate and gadolinium nitrate, temperature, and irradiation...

Gadolinium has been proposed for use as neutron poison for the control of criticality during the spent nuclear fuel dissolution, feed preparation, and solvent extraction.The distribution ratio of gadolinium (Dad) in system TBP-nitrate, concentration profiles of Gd in countercurrent extraction process with TBP and solubility of gadolinium nitrate in aqueous solution are presented. The effects of concentration of nitric acid, sodium nitrate, uranyl nitrate and gadolinium nitrate, temperature, and irradiation of TBP-kerosene on Dad, are investigated.A maximum and a minimum on Dad vs. nitric acid concentration curves at about 3 mol/1 and 7 mol/1 nitric acid are observed respectively. Dad increases with the increase of concentration of sodium nitrate in aqueous phase. Maximum and minimum of Dad are not found in sodium nitrate solution. Uranium concentration in equilibrated organic phase influences Dad significantly. The change of Dad is not appreciable when gadolinium concentration in aqueous phase increases to 13 g/1.No difference can be seen between Dad with solvent irradiated by 80Co to a level of 3.6×105 Gy and DGd with solvent not irradiated.Cascade countercurrent extraction tests are carried but and decontamination factors from Gd of 104-105 are obtained.The effects of some factors such as concentration of nitric acid and uranium,and temperature on the solubility of gadolinium nitrate in aqueous solution are investigated. The results show that the value of solubility of gadolinium nitrate in aqueous solution decreases with the increase of concentration of nitric acid and uranyl nitrate.

本文研究了HNO_3浓度,UO_2(NO_3)_2浓度,Gd(NO_3)_3浓度,NaNO_3浓度以及温度和溶剂辐照对钆分配系数的影响。对S形分配曲线进行了初步探讨。用串级实验研究了钆在逆流萃取过程中的走向和分布。求得钆的净化系数。研究和测定了不同HNO_3浓度、不同UO_2(NO_3)_2浓度和不同温度下Gd(NO_3)_3在水中的溶解度。

Zinc mixed with quality protein will improve pregnant rate of female mice dad increase the number of baby mice at a birth. In the cold winter when temperature reduced suddenly, it will arise the survival rate of mother mice and decrease the mortality of baby mice. This indicates that quality protein mixed with zinc is apable of improving mice' generative power and cold resistant ability.

鼠摄入锌加优质蛋白质的饲料,可提高鼠怀孕率、平均每窝产仔鼠数和仔鼠体重。在严冬气温剧降时又能使母鼠生存率提高,仔鼠死亡率降低。表明锌加优质蛋白质有促进小白鼠生殖和增强御寒的作用。

After cold treatment (4℃) for 19-21 h, the amplitude of action potential and the action potential duration at 50% of repolarization of the rat ventricular fibers were unchanged significantly, whereas that of 90% of repolarization increased remarkably.Low K+(0.75-1.5 mrnol/L) superfusion might induce delayed af terdepolarization (DAD) and triggered activity (TA) in the papillary muscle fibers treated with cold storage. Application of electrical stimulation either did not affect or only resettle the rhythm...

After cold treatment (4℃) for 19-21 h, the amplitude of action potential and the action potential duration at 50% of repolarization of the rat ventricular fibers were unchanged significantly, whereas that of 90% of repolarization increased remarkably.Low K+(0.75-1.5 mrnol/L) superfusion might induce delayed af terdepolarization (DAD) and triggered activity (TA) in the papillary muscle fibers treated with cold storage. Application of electrical stimulation either did not affect or only resettle the rhythm of the TA, but it could not stop it.Adrenaline (1μg/ml) or high. concentration of Ca2+ (5.4 mmol/L) could iacrease the amplieude of DAD and made the TA more easily be induced. Both T1+ (1.5 mmol /L) and Mn2+ (3mmol/L) could inhibit DAD and TA. The results showed that the electrophisiological properties of the ventricular fibers of rat heart were changed after cold storage. It is suggested that the sensitivity of Na-pump in the cell membrane is increased to the pump-inhibitors and the DAD and TA are induced more easily by low K+ superfusion after cold treatment.

大鼠心室肌纤维经低温(4℃)处理19—21小时后,动作电位幅度及复极50%时的动作电位时程无明显变化,而复极90%的时程明显延长。低钾(0.75—1.5mmol/L)灌流可使低温处理的标本产生迟后去极化(DAD)以及由此产生触发性活动(TA)。施与额外电刺激对TA无影响,或引起该节律的重排,然而不能使之终止。肾上腺素(1μg/ml)或高钙(5.4mmol/L)可以增加DAD幅度,从而使TA更易发生。TI~+(1.5mmol/L)及Mn~(2+)(3mmol/L)可抑制DAD及TA。以上结果表明,低温处理后大鼠心室肌细胞电生理特性发生改变,对钠钾泵抑制剂—低钾—敏感性增高,因而易产生DAD及TA。

 
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