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   胶原 在 消化系统疾病 分类中 的翻译结果: 查询用时:0.036秒
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胶原     
相关语句
  collagenous
    A QUANTITATIVE ANALYSIS ON THE COLLAGENOUS FIBER IN LIVER WITH TOXIC CIRRHOSIS INDUCED BY CARBON TETRACHLORIDE
    四氯化碳中毒性肝硬化肝胶原纤维的定量分析
短句来源
    There was a significant difference between CIR group(0.108±0.036,0.304±0.131)and SO group(0.031±0.015,0.060±0.038)in the intrahepatic content of VEGF and collagenous fibers(P<0.001).
    3.CIR组VEGF平均积分光密度值(0.108±0.036)以及胶原纤维面密度值(0.304±0.131)与SO组相比(0.031±0.015,0.060±0.038)均具极显著性差异(P<0.001)。
短句来源
    Collagenous colitis
    胶原性结肠炎
短句来源
    Primary AL-amyloidosis, ulcerative colitis and collagenous colitis in a 57-year-old woman: A case study
    患原发性AL-淀粉样变、溃疡性结肠炎和胶原性结肠炎的57岁女性患者:1例病例研究
短句来源
    Colonic mucosal tears in collagenous colitis
    胶原性结肠炎结肠黏膜的撕裂
短句来源
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  collogen
    Results There was a prominent positive correlation between HA and the degree of espophageal varices( r = 0. 446,0. 325) P =0.001,r=0.012. There was no correlation between laminin, human procollogen type Ⅲ and collogen type IV and the degree of esophageal varices. Conclusion Serum hyaluronate is a good parameter reflecting the degree of esophageal varices.
    结果 透明质酸和年龄与食管静脉曲张程度呈显著正相关(r=0.446,r=0.325;P分别为0.001及0.012(双侧检验),而层粘连蛋白、三型前胶原、四型胶原与食管静脉曲张程度均无明显相关。结论 血清透明质酸比层粘连蛋白更能反映食管静脉曲张的有无及程度。
短句来源
    The passaged HSCs were randomly divided into 10 groups and different concentrations of β-Est,2-hydroxyestradiol (2OHE) or 2-methoxyestradiol (2MeOE) were added to the cell groups separately. After 72 hours incubation,the degree of cell proliferation,hyahuronicacid and type Ⅳ collogen secretion,α-smooth muscle actin (α-SMA) and estrogen receptor (ER) expression were determined by MTT assay,ELISA or immunohistochemistry,respectively.
    初次传代后 ,HSC随机分成 10组 ,分别加入不同浓度 β Est、2OHE、2MeOE ,加药后72h ,采用MTT、ELISA及免疫组化法分别检测HSC增殖、培养液中透明质酸 (HA)和Ⅳ型胶原 (CⅣ )含量及细胞中α 平滑肌肌动蛋白 (α SMA)、雌激素受体 (ER)表达。
短句来源
    Objective: To study clinical evaluation of serum type Ⅳ collogen in chronic liver diseases in comparison with serum laminin, hyaluronic acid.
    目的:研究血清Ⅳ型胶原在慢性肝病上的诊断价值并与血清层粘蛋白、透明质酸比较.
短句来源
    Methods: Serum type Ⅳ collogen, laminin, hyaluronic acid were determined by means of RIA in 114 patients with various liver diseases and 30 healthy control.
    方法:用放免法(RIA)测定114例各种肝病患者及30例正常对照者的血清Ⅳ型胶原、层粘蛋白和透明质酸的水平.
短句来源
    Results: Serum type Ⅳ collogen levels was significantly increased in chronic hepatitis, liver cirrhosis and primary hepatic carcinoma (P< 0.001). Serum laminin and hyaluronic acid levels were increased also ( P < 0.05).
    结果:与正常对照比较慢性肝炎、肝硬化和肝细胞癌患者血清Ⅳ型胶原含量升高极显著(P<0.01),层粘蛋白和透明质酸含量亦显著升高(P<0.05).
短句来源
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  pro collagen
    Variations of Hyaluronic Acid,Laminin,Human Procollagen Type Ⅲ and Type Ⅳ collagen in the Serums of the patients with Liver Cirrhosis
    肝硬化时血清透明质酸层粘蛋白人 Ⅲ 型前胶原 Ⅳ 型胶原含量的变化
短句来源
    To determine the relationship between hyaluronic acid(HA),typeⅢ procollagen(PCⅢ),type-Ⅳ collagen(CⅣ) or proline dipeptidase(PLD) and degree of liver fibrosis.
    探讨肝病患者血清透明质酸(HA),Ⅲ型前胶原(PCⅢ),Ⅳ型胶原(CⅣ)及脯氨酸肽酶(PLD)水平与肝纤维化程度的关系。
短句来源
    Methods TGFβ-1 and hyalauronic acid (HA), laminin (LN), type III procollagen (PC III), and type IV collagen (IV-C) were assessed by ELISA and the data were statistically analyzed in 108 patients with type B posthepatitic cirrhosis and 97 normal controls.
    方法分别检测108例乙型肝炎后肝硬化患者(其中Child-pugh分级A级47例,B级40例,C级21例)和97例正常对照血清中TGFβ-1和透明质酸(HA)、层粘蛋白(LN)、Ⅳ型胶原(IV-C)、Ⅲ型前胶原(PCIII)。
短句来源
    Methods The radioimmunoassaywas usedtodetect the levels of plasma ET-1, serum hyaluronic acid (HA), laminin(LN), type Ⅲ procollagen(PⅢP) and collagen type IV(Ⅳ-C) in 23 cases with acute hepatitis B , 81 cases with chronichepatitis B and 64 cases with posthepatitic cirrhosis .
    方法采用放射免疫法测定急性乙型肝炎、慢性乙型肝炎和肝炎肝硬化患者血浆ET-1、血清透明质酸(HA)、层粘蛋白(LN)、Ⅲ型胶原肽(PⅢP)和Ⅳ型胶原(Ⅳ-C)水平。
短句来源
    A Study on the relationship between serum levels of hyaluronic acid, type Ⅲ procollagen, type Ⅳ collagen and hepatic fibrosis
    血清透明质酸、Ⅲ型前胶原、Ⅳ型胶原水平与肝纤维化的关系
短句来源
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  ⅳ collagen
    DIAGNOSTIC VALUE OF SERUM TYPE Ⅳ COLLAGEN AS A MARKER OF HEPATIC FIBROSIS
    血清Ⅳ型胶原对肝纤维化诊断价值的研究
短句来源
    Study on type Ⅳ collagen and fat-storing cells in fibrotic rat liver treated by tetrandrine
    汉防己甲素对实验性大鼠肝纤维化Ⅳ型胶原及储脂细胞的影响
短句来源
    ESTABLISHMENT OF A SANDWICH ELISA FOR THE DETERMINATION OF SERUM HUMAN TYPE Ⅳ COLLAGEN AND ITS PRELIMINARY APPLICATION
    人血清Ⅳ型胶原ELISA检测法的建立与初步应用
短句来源
    A study on type Ⅰ,Ⅱand Ⅳcollagen production in CCL 4 induced rat liver fibrosis.
    CCl_4诱导大鼠肝纤维化动物模型Ⅰ、Ⅲ及Ⅳ型胶原生成变化的研究
短句来源
    Variations of Hyaluronic Acid,Laminin,Human Procollagen Type Ⅲ and Type Ⅳ collagen in the Serums of the patients with Liver Cirrhosis
    肝硬化时血清透明质酸层粘蛋白人 Ⅲ 型前胶原 Ⅳ 型胶原含量的变化
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  collagenous
Also, it has been found for the first time that the protein matrix is constructed of a collagenous protein.
      
On this physical basis, the specific waveband of high efficiency for transmission of infrared rays exists in the collagenous fibre in a liquid crystal state.
      
In only 22.27% cases of the experimental group, surgical defects filled with cartilaginous tissue on the background of distinct destruction of collagenous matrix in the native cartilage.
      
However, in 55.5% of the control group the defect was spontaneously healed by hyaline cartilaginous tissue completely or partially on the basis of slight destruction of collagenous matrix.
      
The results suggest that Papain did not ameliorate the recovery of cartilage defects acquired through surgically-induced injury of collagenous matrix in native cartilage.
      
更多          
  collogen
Using the rat as an experimental model, we evaluated the effect of estrogen-replacement therapy and its timing on clitoral-cavernosal collogen fiber content after oophorectomy.
      
  pro collagen
Figure 3 Immunocytochemical staining of procol lagen I in germ cell clusters formed from the cul tured seminiferous tubules of 6-day-old mice.
      
Proal chains of the type obtained from acid-extracted pro collagen do not appear in substantial quantities after a chase.
      
Thereafter, we evaluated the ability of SIS3 in the suppression of the TGF1-induced type I pro collagen up-regulation in human dermal fibroblasts.
      
The concentration of NaCl in the supernatant was increased to 25%, and pro collagen and collagen were precipitated by stirring at 40 over night.
      
The extent to which proa chains from acid-extracted pro collagen are reduced in size is difficult to evaluate.
      
  其他


In the present study, liver fibrosis of rats was induced by the use of diethylnitrosamine(DEN). And through liver biopsies at certain intervals, we observed primarily the sequential changes of Ito cells(ICs) and their relation to the genesis of liver fibrosis. It was found that in the course of the genesis and development of liver fibrosis, ICs underwent marked proliferation with collagen deposition in Disse's space and gradual transition to fibroblasts. The proliferated ICs are mainly distributed in the peripheries...

In the present study, liver fibrosis of rats was induced by the use of diethylnitrosamine(DEN). And through liver biopsies at certain intervals, we observed primarily the sequential changes of Ito cells(ICs) and their relation to the genesis of liver fibrosis. It was found that in the course of the genesis and development of liver fibrosis, ICs underwent marked proliferation with collagen deposition in Disse's space and gradual transition to fibroblasts. The proliferated ICs are mainly distributed in the peripheries of the lobule,fibrous septa and the area adjacent to fibrous septa.In end stage of the experiment, IC indices decrease strikingly, which may be due to the transition of ICs to fibroblasts. Such changes are more salient in fibrous septa than in lobule.

本文采用二乙基亚硝胺诱发大鼠肝纤维化,定期进行肝活检,着重观察了Ito细胞(IC)的动态改变及其与肝纤维化发生的关系。结果表明:在肝纤维化的发生发展过程中,IC明显增生,合成胶原蛋白沉积于Disse腔内,并逐步过渡为成纤维细胞;增生的IC主要分布于小叶周边,纤维间隔及邻近间隔的肝小叶内;实验后期,IC指数明显下降,可能与IC转变为成纤维细胞有关,这种转变纤维间隔比小叶内更明显。

Serum antibody to type I collagen was dete cted in experimental liver fibrosis by passive hemagglutination. Our investigation revealed a high incidence (35%) of the antibody in experimental liver fibrosis. The peak levels of the antibody appear earlier than the deposition of collagen in the liver. Furthermore, there is a significant correlation between the antibody titers and the amount of liver collagen deposition (P<0.05). Measurement of collagen antibody may serve as an early diagnostic marker of liver fibrosis...

Serum antibody to type I collagen was dete cted in experimental liver fibrosis by passive hemagglutination. Our investigation revealed a high incidence (35%) of the antibody in experimental liver fibrosis. The peak levels of the antibody appear earlier than the deposition of collagen in the liver. Furthermore, there is a significant correlation between the antibody titers and the amount of liver collagen deposition (P<0.05). Measurement of collagen antibody may serve as an early diagnostic marker of liver fibrosis and may also provide some indication of the severity.

本文检测了突验性肝纤维化中Ⅰ型胶原抗体,实验结果显示:各实验组的总阳性率为35%。其抗体滴度与肝中胶原沉积量有显著相关性,且抗体滴度峰较胶原在肝中沉积高峰提前,提示Ⅰ型胶原抗体出现,可对肝纤维化胶原沉积早期诊断和肝纤维化进展估计具有一定意义。

Ito cells in rat liver was sonfirmed to express desmin by immunohistochemical method. The study has bcea extended to obser ve the changes of desmin-positive cells, lysozyme-positive cells and fi bronectin in a sequential-model of experimental cirrhosis of rat. It was found that desmin-positive cells which were of stellate configuration increased in number in the necrotic areas as well as the early stage of septa. Elonged desmin-positive cells which showed intermidiate features between Ito cells and myofibroblast...

Ito cells in rat liver was sonfirmed to express desmin by immunohistochemical method. The study has bcea extended to obser ve the changes of desmin-positive cells, lysozyme-positive cells and fi bronectin in a sequential-model of experimental cirrhosis of rat. It was found that desmin-positive cells which were of stellate configuration increased in number in the necrotic areas as well as the early stage of septa. Elonged desmin-positive cells which showed intermidiate features between Ito cells and myofibroblast were prodominent in the cellular fi brous septa. Except for desmin-positive cells in the edge of the fibroces septa, seanty typical fibroblasts appeared instead of desmin-positive cells ia the late stags of septa. The results suggested that Ito cells, myofibroblasts and fibroblasts might belong to the same system and they play an important role in pathogenesis of rhosis. Meanwhile, it was noted that lysozyme-positiye cells and fibroaectin were associated with the desmin-positive cells, which provided the cvi dence in vivo that Kupffer cells and fibronectin might have certain eff ects on the changes of Ito cells.

通过免疫组化、组化、电镜及图象分析对四氯化碳诱发大鼠肝硬化过程中结强白(desmin,DM)阳性细胞、溶菌酶(lysozyme,LZ)阳性细胞和纤维联接蛋白(fibronectin,FN)及胶原纤维、网状纤维的演变作了动态观察,发现实验早期DM阳性细胞增加明显,DM表达增强;中期形成以DM阳性细胞为主的细胞纤维间隔;晚期纤维间隔中DM阳性细胞仅存在于间隔边缘部。FN除峰值前移外,与DM阳性细胞的演变基本平行。LZ阳性细胞经历由递增到递减的变化过程。结果提示DM免疫组化染色为Ito细胞及其过渡型的良好标志;Ito细胞、肌纤维母细胞、纤维母细胞可能属于同一细胞系统的不同阶段形式,它们肝硬化的组织发生中起着重要作用,并可能受FN及Kupffer细胞的影响。

 
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