16 wk of treatment with Cap lessened medial thickness of aortae(104.7±6.6 vs 135.7±8.1μm)and abnormal ultrastructural signs of ASMC from SHR including heterogeneous population of nuclei,swelling of mitochondria and tubular systems as Well as decreased [Ca2+] i in ASMC.
New data have been considered concerning the previously unknown intraembryonic hemopoietic organ in mammals, a region of aorta-gonad-mesonephros arising in embryogenesis simultaneously with the yolk sac.
A high efficiency of transfection of primordial germ cells isolated from the gonads has been obtained after DNA injection into the dorsal aorta of 2.5-day-old chicken embryos.
Sialyltransferase Activity in Normal and Atherosclerotic Human Aorta Intima
Sialyltransferase activity has been determined in Golgi membrane fractions isolated from atherosclerotic and normal intima of human aorta by measuring the transfer of N-acetylneuraminic acid (NeuAc) from CMP-NeuAc to asialofetuin.
Effect of L-Arginine on Na+,K+-ATPase Activity in Rat Aorta Endothelium
Histopathological study of congenital aortic valve malformations in 32 children
The histopathological characteristics of congenital aortic valve malformations in children were investigated.
Among 32 children with congenital aortic valve malformations, the age was ranged from six to 18 years, with a mean of 14.9 years, and there were 27 boys and five girls (male: female = 5.4:1).
There were five cases of aortic stenosis (AS, 15.62%), 25 cases of aortic insufficiency (AI, 78.13%) and two cases of AS-AI (6.25%), without other valve diseases.
Twenty cases still had other congenital heart diseases: ventricular septal defect (19 cases), patent ductus arteriosus (two cases), double-chambered right ventricle (one case), aneurysm of the right anterior aortic sinus of valsalva (three cases).
In 2 cases the right coronary artery was without significant atherosclerotic lesions and coursed between the aorta and pulmonary trunk.
The Rashkind-occluder was developed to close persistant ducts between the aorta and pulmonary artery.
Further diagnostics showed a dissected aneurysm of the aorta ascendens (Stanford type A) and a bicuspid aortic valve.
After optimizing medical treatment with an ACE inhibitor and thiazide diuretics, the patient underwent early elective surgical correction by suture of the ruptured aneurysm from the aorta and from the right ventricular outflow tract.
Because of the excellent sensitivity and specificity of transesophageal echocardiography, its findings are sufficient to provide the indication for emergency thoracotomy and replacement of the aorta.