助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   peripheral tolerance 的翻译结果: 查询用时:0.008秒
图标索引 在分类学科中查询
所有学科
基础医学
更多类别查询

图标索引 历史查询
 

peripheral tolerance
相关语句
  外周耐受
     Peripheral tolerance also involves in the deletion of autoreactive T cells, which includes all the other means, such as DCs and regulatory T cells.
     因此,机体的免疫系统还会通过其它方式灭活及清除胸腺外的自身反应性T细胞,我们称之为外周耐受
短句来源
     Recent studies demonstrated that self-reactive T cells existed in peripheral blood, but theywere in unresponsive state or peripheral tolerance.
     近年来研究证实外周成熟淋巴细胞中存在着自身反应性T细胞,但处于功能失活状态; 谓之外周耐受
短句来源
     This review focuses on the mechanisms of autoreactive T cells escaping peripheral tolerance, migration from blood to hair follicles, and evidence that alopecia areata is mediated by T cells.
     综述自身反应性T细胞逃逸外周耐受、从外周血向毛囊迁移,及其介导斑秃发病的证据。
短句来源
     The exosomes produced by immature DCs can maintain peripheral tolerance,while exosomes produced by mature DCs can stimulate effector T cells. Therefore the exosomes play a important role in inducing immune tolerance.
     非成熟DC(iDC)产生的外染色体能够维持外周耐受,而成熟DC(mDC)产生的外染色体能够刺激效应性T细胞,因此外染色体在诱导免疫耐受中发挥着重要作用。
短句来源
  外周免疫耐受
     More recent researches have shown that regulatory T cell is a key element in peripheral tolerance.
     越来越多的研究表明调节T细胞是外周免疫耐受的关键。
短句来源
     As one of population of antigen presenting cells, Oendntic cells (DCs) not only can stimulate immune response of T cells but also play an important role in the establishment of both central as well as peripheral tolerance.
     树突状细胞作为一类重要的抗原提呈细胞,不仅能激发免疫应答,而且在中枢免疫耐受和外周免疫耐受中发挥着重要作用。
短句来源
  “peripheral tolerance”译为未确定词的双语例句
     PD-L and PD-1 interaction involves in maintenance of peripheral tolerance.
     PD-1也参与了一系列疾病的发病。
短句来源
     Objective CD4~+CD25~ high regulatory T cells (Treg) have been shown to play an important role in maintaining peripheral tolerance against self and foreign antigens, and in suppressing T cell immune response.
     目的观察不同类型HBV感染患者外周血CD4+CD25high调节性T细胞(Treg)的频率和临床指标的相关性。
短句来源
     Recently, dendritic cells (DCs) are found to play a dual role in the immunological system. Apart from inducing immune response as antigen presenting cells (APCs), DCs can also induce central and peripheral tolerance.
     近年来,树突状细胞(dendritic cells,DCs)被发现在免疫系统中扮演着双重角色,除作为抗原提呈细胞(antigen presenting cells,APC)诱发免疫反应外,还能诱导中枢或周围性免疫耐受。
短句来源
     Part2: Deficiency in both central and peripheral tolerance is essential for the development of MLDS-DM To further study the role of abnormal immunotolerance mechanism in the development of diabetes , the makeup and function of cells in thymus was observed and the frequency and function of CD4+CD25+Treg with immunoregulatory function in the spleen was detected. Ⅰ.
     说明模型鼠胸腺功能异常可能是导致自身反应T 细胞和CD4~+CD25~+Treg 的胸腺选择异常的原因。
短句来源
     Objective: Recent researches showed that dendritic cells can either initiate T cell immunoreaction or promote peripheral tolerance depending on their state of maturaton. Tolerogenic dendritic cells(Tol-DC) have been defined by immature phenotype and the ability to inhibit T cell responses. RelB is a critical nuclear transcription factor NF- κB family member required for myeloid DC maturation.
     树突状细胞(dendritic cell,DC)具有激活免疫应答或诱导免疫耐受的功能,未成熟状态的树突状细胞倾向于诱导免疫耐受产生,被称为“致耐受DC(tolerogenic dendritic cell,Tol DC)”。
短句来源
更多       
查询“peripheral tolerance”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  peripheral tolerance
One is that tumors induce peripheral tolerance of tumor-specific CD8+ T cells.
      
Experimental animal models for autoimmunity have demonstrated the existence and crucial role of CD4+CD25+ T regulatory (Tr) cells in suppressing autoreactive T cells and promoting peripheral tolerance.
      
However, the recovery of the first graft was not associated with antigen-specific peripheral tolerance.
      
In the experimental colitis model NK1.1+ lymphocytes play a dual role: In the presence of peripheral tolerance they may be accountable for keeping the high CD4+IL-4+/CD4+IFN-γ+ ratio and disease alleviation.
      
IL-2, through its pivitol role in activation-induced cell death (AICD), is involved in peripheral tolerance through the elimination of self-reactive T cells.
      
更多          


Immune system how to recognize self and non-self is immunotheoretical core subject.Self antigens are tolerized by self-reactive clone deletion in embryonic phase, non-self antigens areeliminated through immunoresponsiveness,which are the mechanisms of self and non-self recognition. Recent studies demonstrated that self-reactive T cells existed in peripheral blood, but theywere in unresponsive state or peripheral tolerance. Multiple mechanisms participated in the formation process of immunotolerance, including...

Immune system how to recognize self and non-self is immunotheoretical core subject.Self antigens are tolerized by self-reactive clone deletion in embryonic phase, non-self antigens areeliminated through immunoresponsiveness,which are the mechanisms of self and non-self recognition. Recent studies demonstrated that self-reactive T cells existed in peripheral blood, but theywere in unresponsive state or peripheral tolerance. Multiple mechanisms participated in the formation process of immunotolerance, including interaction of immune cells, molecular recognition,signal transduction ajnd so on. Further studies to mechanism of immunotolerance can providetheoretical basis for immunoresponse and immunoregulation and promote the development of immunological theoly.

免疫系统如何识别“自己”和“非己”,这是免疫学理论的核心问题。由于在胚胎期自身反应性细胞克隆被排斥,即形成对自身抗原的耐受;但对外源性“非己”成分能产生免疫应答予以清除,此即免疫系统识别“自己”和“非己”的机制。近年来研究证实外周成熟淋巴细胞中存在着自身反应性T细胞,但处于功能失活状态;谓之外周耐受。目前已明确免疫耐受的形成涉及多种机制的参与,包括免疫细胞的相互作用、免疫细胞的分子识别、信号传递、基因表达等不同层次的调节。对免疫耐受机理的研究可为阐明免疫应答及免疫调节的机制提供依据,必将推动免疫学基础理论研究的发展。

More recent researches have shown that regulatory T cell is a key element in peripheral tolerance.CD4~+CD25~+ regulatory T cell plays a very important role in immune tolerance,autoimmune diseases,graft and tumor development,in which TGF-β is a requisite partner.In some autoimmune diseases like systemic lupus erythematosus,inflammatory bower diseases, there are defects in CD4~+CD25~+ regulatory T cells,and they often correlate with active diseases.Through modifying peripheral regulatory T cells...

More recent researches have shown that regulatory T cell is a key element in peripheral tolerance.CD4~+CD25~+ regulatory T cell plays a very important role in immune tolerance,autoimmune diseases,graft and tumor development,in which TGF-β is a requisite partner.In some autoimmune diseases like systemic lupus erythematosus,inflammatory bower diseases, there are defects in CD4~+CD25~+ regulatory T cells,and they often correlate with active diseases.Through modifying peripheral regulatory T cells and retransfusing them back to patients with autoimmune diseases will probably be a promising method in treating these diseases.

越来越多的研究表明调节T细胞是外周免疫耐受的关键。CD4+CD25+调节T细胞在免疫耐受、自身免疫病、移植、肿瘤等方面均有着极其重要的作用,并需要TGF-β参与。在很多自身免疫性疾病如SLE、炎症性肠病中,CD4+CD25+调节T细胞的数量和/或功能存在显著异常,且多与疾病活动正相关。通过对自身免疫病外周血T细胞亚群进行修饰再自体回输可能是治疗这类疾病新的突破。

As one of population of antigen presenting cells, Oendntic cells (DCs) not only can stimulate immune response of T cells but also play an important role in the establishment of both central as well as peripheral tolerance. The DCs in the thymus have )been subdivided into two populations, lymphoid DCs and myeloid DCs. They can induce negative selection of effective T cells and positive selective of regulatory T cells. This review will discuss the origin of mtrathymic DCs and Us mechanisms of inducing immune...

As one of population of antigen presenting cells, Oendntic cells (DCs) not only can stimulate immune response of T cells but also play an important role in the establishment of both central as well as peripheral tolerance. The DCs in the thymus have )been subdivided into two populations, lymphoid DCs and myeloid DCs. They can induce negative selection of effective T cells and positive selective of regulatory T cells. This review will discuss the origin of mtrathymic DCs and Us mechanisms of inducing immune tolerance.

树突状细胞作为一类重要的抗原提呈细胞,不仅能激发免疫应答,而且在中枢免疫耐受和外周免疫耐受中发挥着重要作用。胸腺中树突状细胞分为淋巴源性和髓源性,参与效应性T细胞的阴性选择和调节性T细胞的阳性选择过程。本文就胸腺内树突状细胞的来源、特点以及在中枢耐受中的机制作一综述。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关peripheral tolerance的内容
在知识搜索中查有关peripheral tolerance的内容
在数字搜索中查有关peripheral tolerance的内容
在概念知识元中查有关peripheral tolerance的内容
在学术趋势中查有关peripheral tolerance的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社