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The characteristics of the spontaneous reactivation of cholinesterase(ChE)activity of rat's blood in vitro after acute dichlorvos and furadanpoisoning was investigated.The results demonstrated that the spontaneousreactivation of inhibited ChE activity reach summit value within 72 hours.On the 17th day after poisoning,the ChE activity was 68.9% in the controlgroup while 16.2% and 41.9% in the dichlorvos and furadan group respec-tively.The results and the significance of the ChE activity reactivation inthe rat's... The characteristics of the spontaneous reactivation of cholinesterase(ChE)activity of rat's blood in vitro after acute dichlorvos and furadanpoisoning was investigated.The results demonstrated that the spontaneousreactivation of inhibited ChE activity reach summit value within 72 hours.On the 17th day after poisoning,the ChE activity was 68.9% in the controlgroup while 16.2% and 41.9% in the dichlorvos and furadan group respec-tively.The results and the significance of the ChE activity reactivation inthe rat's postmortem blood died of dichlorvos and furadan poisoning wasdiscussed. 作者测定了中毒鼠血胆碱酯酶活性在体外室温下的动态变化,观察研究胆碱酯酶自动复能的特点。结果表明中毒鼠血胆碱酯酶活性体外自动复能在72小时内达最大值;敌敌畏中毒鼠血胆碱酯酶自动复能较呋喃丹组幅度大而下降也快;至第17天,与对照组相比,敌敌畏中毒鼠血胆碱酯酯活性仍有显著性差异。根据实验结果就中毒鼠血胆碱酯酶自动复能的法医学意义作了讨论。 In order to evaluate the diagnostic value of determing the serum strotium levelfor the drowning diagnosis,we carried out this study.The results of our expe-rirnental study are summarized as follows:(1).The blood Sr level determinationcould be used as a confirmatory test of drowning merely at the early stage(wi-thin 5 min)of drowning;(2).It could give some help for diagnosing the case ofdrowning submerged in water within 24 hours.It was showed that the durationof submersion has influence upon the postmortem... In order to evaluate the diagnostic value of determing the serum strotium levelfor the drowning diagnosis,we carried out this study.The results of our expe-rirnental study are summarized as follows:(1).The blood Sr level determinationcould be used as a confirmatory test of drowning merely at the early stage(wi-thin 5 min)of drowning;(2).It could give some help for diagnosing the case ofdrowning submerged in water within 24 hours.It was showed that the durationof submersion has influence upon the postmortem blood Sr level.The blood Srlevel was measured in two submerged cases in medico-legal practice.One died ofdrowning and the another was postmortem sbmersion after electrocusion.It is inter-esting that the results of blood Sr determination of human being were more acc-urate than experimental animals.Therefore,we consider that the further studyabout this project is required. 为评价血锶含量测定对诊断鉴定溺死的实用价值,作者用家兔进行实验,分别测定溺死与死后入水家兔左心血中锶含量。结果证实:1.死后较短时间内血锶含量测定确可鉴定溺死;2、死后24小时内仅可帮助鉴定溺死。实验表明水中浸泡时间因素对血锶含量确有显著影响。两例实际检案的应用观察,较实验性研究为佳,值得进一步研究。 The postmortem redistribution of aconitine(AC) and its influencing factors by orally ingested Aconitum brachypodum Diels (AbD) in rabbits were studied. The results showed that postmortem AC redistribution did exist, and the diffusion along a concentration gradient was the major influencing factor on it. Change of temperature and incomplete distribution in life also influenced it.Besides those mentioned above, there were other influencing factors. These may be related to postmortem blood movement and toxin... The postmortem redistribution of aconitine(AC) and its influencing factors by orally ingested Aconitum brachypodum Diels (AbD) in rabbits were studied. The results showed that postmortem AC redistribution did exist, and the diffusion along a concentration gradient was the major influencing factor on it. Change of temperature and incomplete distribution in life also influenced it.Besides those mentioned above, there were other influencing factors. These may be related to postmortem blood movement and toxin released from cells occurring as part of the processes of autolysis and putrefaction. POSTMORTEMREDISTRIBUTIONKINETICSOFACONITINEINRABBITSXuWei;HuBingwei(DepartmentofToxicology,FacultyofForensicMedicine,Xi'anMed...
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