助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   tgf 在 消化系统疾病 分类中 的翻译结果: 查询用时:0.168秒
图标索引 在分类学科中查询
所有学科
消化系统疾病
泌尿科学
特种医学
肿瘤学
中药学
外科学
眼科与耳鼻咽喉科
儿科学
更多类别查询

图标索引 历史查询
 

tgf
相关语句
  转化生长因子
    To study the relationship between serum TGFβ1 and liver fibrosis parameters in posthepatitic cirrhosis patients with different Child-pugh stages.
    目的探讨不同Child-pugh分级的患者血清转化生长因子-1(TGFβ-1)与血清肝纤维化指标的关系。
短句来源
    Objective To explore the association of transforming growth factor β1(TGFβ1),collagen type Ⅳ (IVC),hyauline(HA) and collagen type Ⅲ N-terminal peptide(PⅢNP) with liver fibrosis.
    目的探讨血清转化生长因子-β1(TGFβ1)、Ⅳ型胶原(IVC)、透明质酸(HA)及Ⅲ型前胶原N端肽(PⅢNP)的浓度与肝硬化的关系。
短句来源
    3. TGFβ1 can prevent HOC from excessive proliferation in the course of formation and reversion of rat cirrhosis treated with DMN.
    3、转化生长因子(TGFβ1)在DMN大鼠肝硬化形成与逆转过程中可能起到控制肝脏卵圆细胞过度增殖的作用。
    The serum TGF β1 in the patients with chronic hepatitis B involving in liver cell damage and liver fibrosis formation
    转化生长因子β1在慢性乙型肝炎患者肝细胞损伤和肝纤维化形成中的意义
短句来源
    Study of Serum TGF β_1 of Patients in Liver Disease
    肝病患者血清转化生长因子β_1水平及其临床意义
短句来源
更多       
  “tgf”译为未确定词的双语例句
    Study on TGFβ_1 Inducing Fibronectin Expression and Promoting Hepatic Fibrosis
    TGFβ_1诱导纤维粘连蛋白表达促进肝纤维化的研究
短句来源
    Study on the relationship between the high proliferation of gastric epithelial cells in Hp infection and the expression of TGF α ECFR
    幽门螺杆菌感染的高增殖状态及其与TGF-α、EGFR表达的关系
短句来源
    THE MEASUREMENT OF SERUM TGFβ_1,, Ⅰ-C AND Ⅲ -C IN PATIENTS WITH CHR0NIC LIVER DISEASES AND THE RELATIONSHIP BETWEEN THESE INDICES AND HEPATIC FIBROSIS
    慢性肝病患者血清TGFβ1、Ⅰ-C、Ⅲ-C水平及其与肝纤维化的关系
短句来源
    Methods TGFβ-1 and hyalauronic acid (HA), laminin (LN), type III procollagen (PC III), and type IV collagen (IV-C) were assessed by ELISA and the data were statistically analyzed in 108 patients with type B posthepatitic cirrhosis and 97 normal controls.
    方法分别检测108例乙型肝炎后肝硬化患者(其中Child-pugh分级A级47例,B级40例,C级21例)和97例正常对照血清中TGFβ-1和透明质酸(HA)、层粘蛋白(LN)、Ⅳ型胶原(IV-C)、Ⅲ型前胶原(PCIII)。
短句来源
    Linear regression analysis suggested that TGFβ1 positively correlated with HA, LN, PC III and IV-C.
    各组血清HA、IVC、LN、PCIII均与血浆TGFβ1呈明显正相关。
短句来源
更多       
查询“tgf”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  tgf
Efficient bioinformatic analysis has fundamentally determined that KIAA0372 is an extracellular protein which may be involved in TGF-β signaling.
      
We studied the effect of extractive substances (ES) and total glycoside fraction (TGF) from Panax ginseng on plant cell growth.
      
Such are the suggested effects on telomerase of Myc, p53, Waf1, protein kinases B and C, Wnt5A, TGFβ, WT1, and estrogens.
      
However, Myc, p53, WT1, estrogens, protein kinases B and C, and TGFβ can also directly influence telomerase independently of the G1-S checkpoint mechanism.
      
The aim of this study was to evaluate how growth factors (PDGF-BB, EGF, and TGF-1β) modulate hyaluronan synthase (HAS) activities in normal or stressed cultured human skin fibroblasts.
      
更多          


Objective:To study the mechanism and early diagnosis of liver fibrosis and provide a theoretical basis for its therapy.Methods:Hepatic Ito cells,hepatocytes,endothelial cells and Kupffer cells were cultured.The effects of cytokines,extracellular matrix(ECM) and some traditional Chinese medicines on cell collagen mRNA expression were studied.Some collagens,glycoprotein and proteoglycans were isolated and purified,and corresponding assaying methods were set up. Results:The expression of collagen mRNA was increased...

Objective:To study the mechanism and early diagnosis of liver fibrosis and provide a theoretical basis for its therapy.Methods:Hepatic Ito cells,hepatocytes,endothelial cells and Kupffer cells were cultured.The effects of cytokines,extracellular matrix(ECM) and some traditional Chinese medicines on cell collagen mRNA expression were studied.Some collagens,glycoprotein and proteoglycans were isolated and purified,and corresponding assaying methods were set up. Results:The expression of collagen mRNA was increased in vivo and in vitro studies on cultured cells and in rat fibrotic liver.Serum levels of ECM were parallelled with the degrees of hepatic injuries and fibrogenesis.Conclusions:The increased deposition of ECM proteins is due to the increased transcription of ECM genes,which are regulated by cytokines,such as TGF-β,PDGF, EGF,TNF-α,IL-1,IL-6,IFN-γ,etc.Assessment of serum ECM contents may be used as an index for early diagnosis and treatment of liver fibrosis.

目的:研究肝纤维化的发生机制和诊断方法,为治疗提供理论依据。方法:分离动物肝间质和实质细胞,观察细胞因子、细胞外间质(Extracellularmatrix,ECM)、中药等对细胞及动物肝脏中胶原mRNA表达的影响;提纯ECM成分,制备抗体并建立检测方法,以血清中ECM含量变化判断早期肝纤维化的形成。结果:肝纤维化发生时,肝内细胞胶原mRNA表达增强,细胞因子有重要调节作用。血清中ECM水平与肝组织纤维增生变化相平行。结论:肝纤维化大量ECM增生原因为其基因激活转录所致,这种激活受细胞因子调节。ECM的血清学检测可作为早期诊断和监测临床治疗情况的指标。

The purpose of the present study is to analyse the expression and localization of PDGF, bFGF, EGF, TGFα in gastric coronary veins of cirrhotic and non-cirrhotic patients with immunohistochemistry technique. The strong positive rates were 93%, 89%, 70% and 68% respectively in cirrhotic patients (n=30), and 0% in non-cirrhotic patients (n -10). It is concluded that the portal vein system could produce growth factors during cirrhosis , and then the growth factors could act on the portal vein system by autocrine...

The purpose of the present study is to analyse the expression and localization of PDGF, bFGF, EGF, TGFα in gastric coronary veins of cirrhotic and non-cirrhotic patients with immunohistochemistry technique. The strong positive rates were 93%, 89%, 70% and 68% respectively in cirrhotic patients (n=30), and 0% in non-cirrhotic patients (n -10). It is concluded that the portal vein system could produce growth factors during cirrhosis , and then the growth factors could act on the portal vein system by autocrine and paracrine, resulting in vascular remodeling and disturbance of its function. It is clear that this experiment gives fresh insight into the growth factor blocker/antagonist treatment of vascular remodeling.

采用免疫组织化学技术,研究血小板源性生长因子(PDGF)、碱性成纤维细胞生长因子(bFGF)、表皮生长因子(EGF)和转化生长因子α(TGFα)在肝硬变(n=30)和非肝硬变患者(n=10)胃冠状静脉壁的表达与分布.结果:肝硬变患者的强阳性检出率分别为93%、89%、70%和68%,非肝硬变者均为0.提示肝硬变门静脉高压症时,门静脉系统的血管壁可产生多种生长因子,并以旁分泌和自分泌方式作用于血管本身,引起血管构形改建和功能障碍.为生长因子阻断/拮抗疗法用于防治血管构形改建提供理论基础.

TGF-βisthemostimportantcytokineintheprocessofliverfibrosis.TheeffectofTGF-βmonoclonalantibodyonNIH/3T3cellproliferationandprocollagenⅢexpressionwasstudiedwithcellMTTbioassayandinsituhybridization.OurresultsindicatedthattheTGF-βmonoclonalantibodyinhibited3T3cellproliferationandhenceinhibitedprocollagenⅢmRNAexpression.Thesefindings.suggestthatculturedfibroblastinvitromayhaveautocrinesecretionofTGF-β.TGF-βmonoclonalantibodypreventscellproliferationandprocollagenexpressionsignificant-ly.

TGF-β在肝纤维化的形成中起着重要作用。以MTT法及原位杂交检测法研究TGF-β单抗对NIH/3T3细胞增殖及Ⅲ型前胶原表达的影响。结果表明,TGF-β单抗抑制3T3细胞增殖,并显著抑制细胞Ⅲ型前胶原mRNA的表达,提示离体培养的成纤维细胞可能存在TGF-β自分泌,TGF-β单抗能显著阻断其效应,阻止细胞增殖及胶原表达。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关tgf的内容
在知识搜索中查有关tgf的内容
在数字搜索中查有关tgf的内容
在概念知识元中查有关tgf的内容
在学术趋势中查有关tgf的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社