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grafting tumors in mice
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     After grafting, the R.
     接枝条件:剂量率为0.18Mrads/hr,总辐照剂量为4.32Mrads,接枝率为6.5%。
短句来源
     Trichogenic Tumors
     毛源性肿瘤
短句来源
     THE GRAFTING OF SILK
     蚕丝的接枝
短句来源
     Matastatic tumors;
     转移性肿瘤;
短句来源
     Treatment of aggressive tumors of the femoral head and neck by cryosurgery with cortical bone grafting
     冷冻灭活皮质骨移植治疗股骨头颈部侵袭性肿瘤的疗效观察
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Objective To explore the effect of extract of Euphorbiae in anti-tumor.Methods Seeds of Euphorbiae was ex- tracted by polar grade and isolated by silica gel column chromatography.The exytracts of different concentrations of polar grade and the isolators of chromatography were studied on the anti-tumor activity in vitro(by MTT method)and in vivo (grafting tumors in mice).Results The chloroform extract and the acetone extract from Euphorbiae had trmor inhibition effect on K562,HepG_2 and U937 cell line.Besides,they...

Objective To explore the effect of extract of Euphorbiae in anti-tumor.Methods Seeds of Euphorbiae was ex- tracted by polar grade and isolated by silica gel column chromatography.The exytracts of different concentrations of polar grade and the isolators of chromatography were studied on the anti-tumor activity in vitro(by MTT method)and in vivo (grafting tumors in mice).Results The chloroform extract and the acetone extract from Euphorbiae had trmor inhibition effect on K562,HepG_2 and U937 cell line.Besides,they showed obvious therapeutic efficacy in EAC and S180 in vivo. However,the petroleum ether extract,methanol extract and distilled water extract from Euphorbiac showed no obvious anti- tumor activity basically.The multi-isolators of chromatography of effective extracts manifested stronger cytotoxicity on K562,HL-60 and Hela cell line.Conclusion Besides the known Euphorbiae factor 5,there exist many kinds of cytotoxic substance in Euphorbiae with the anti-tumor activity.

目的探索千金子的抗肿瘤作用。方法采用极性梯次提取与硅胶柱层析分离,并对其不同极性段的提取物和分离物进行了体内(小鼠移植性肿瘤)、外(噻唑蓝染色法)抗肿瘤活性研究。结果千金子的氯仿、丙酮段提取物对 K562,HepG_2和 U937细胞株具有抑瘤作用,对在体的 EAC、S180呈现出明显疗效;其石油醚、甲醇、水段提取物则基本上未显示有明显抗癌活性;该有效提取物的硅胶柱层析的多组分离物对K562,HL-60、Hela 细胞呈现出较强的细胞毒作用。结论除已知的千金子因子5外,千金子中还存在有多种细胞毒物质,其物质有抗肿瘤作用。

Objective It is to explore the anti-tumor effect of valerian iridoids. Methods The iridoids were extracted and isolated from valerian. The pan-iridoids, the iridoid glycosides and the iridoidates were observed on the anti-tumor active in vitro (MTT method) and in vivo (grafting tumors in mice). Results The valerian iridoids, the iridoidates and the iridoid glycosides had strong cytotoxin effects on K_ 562 , HL_ 60 , U_ 937 , HepG_2 and Hale cell. The compound of the iridoidates and the iridoid glycosides...

Objective It is to explore the anti-tumor effect of valerian iridoids. Methods The iridoids were extracted and isolated from valerian. The pan-iridoids, the iridoid glycosides and the iridoidates were observed on the anti-tumor active in vitro (MTT method) and in vivo (grafting tumors in mice). Results The valerian iridoids, the iridoidates and the iridoid glycosides had strong cytotoxin effects on K_ 562 , HL_ 60 , U_ 937 , HepG_2 and Hale cell. The compound of the iridoidates and the iridoid glycosides had direct curative effect on EAC (ascites), S_ 180 (entity) in mice. The intensity of anti-tumor activity was the iridoids with conjugate-bonds > the iridoids with mono-alkene > the iridoid glycosides. Conclusion Valerian iridoids have obvious cytotoxic and anti-tumor effect, especially the iridoidates.

目的探索缬草环烯醚萜的抗肿瘤作用。方法对从缬草中提取分离的总环烯醚萜类物质及其中的环烯醚萜甙与环烯醚萜酯进行体内(小鼠移植性肿瘤)、体外(噻唑蓝染色法)抗肿瘤活性研究。结果缬草环烯醚萜甙与环烯醚萜酯对K562,HL60,U937,HepG2和Hale细胞株具有突出的细胞毒作用,对小鼠在体的EAC(腹水型)、S180(实体型)呈现出明显抑瘤作用;其抗癌活性强度为双烯键结构的环烯醚萜酯>单烯键结构的环烯醚萜酯>环烯醚萜甙。结论缬草环烯醚萜类物质具有显著的细胞毒与抗肿瘤作用,尤其是环烯醚萜酯。

 
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