助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   rat collagen induced arthritis 的翻译结果: 查询用时:0.158秒
图标索引 在分类学科中查询
所有学科
更多类别查询

图标索引 历史查询
 

rat collagen induced arthritis
相关语句
  大鼠胶原性关节炎
     Objective To observe the influences of ligustrazine on the development of rat collagen induced arthritis(CIA) and vascular endothelial growth factor(VEGF).
     目的观察川芎嗪对大鼠胶原性关节炎(CIA)炎症发展和滑膜分泌血管内皮生长因子(VEGF)的影响。
短句来源
  相似匹配句对
     Rat
     鼠(美国电影故事)
短句来源
     Immunolocalization of collagen I & Ⅲ in rat reparative dentin
     I型和Ⅲ型胶原在修复性牙本质形成中的免疫定位
短句来源
     Collagen-gel immobilization culture of rat hepatocytes.
     胶原凝胶固定培养大鼠肝细胞的功能与形态观察
短句来源
     MaterialWistar rat;
     Wistar系大鼠;
短句来源
     Studies of collagen in ccl4-induced rat liver fibrosis
     实验性肝纤维化胶原变化的研究
短句来源
查询“rat collagen induced arthritis”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  rat collagen induced arthritis
This report was the first one to show that a retinoid could reduce antibody production and thereby prevent rat collagen-induced arthritis.
      


bjective To investigate the preventive and therapeutic effects of oral AEBFSS on the rat Collagen-Induced Arthritis(CIA) Methods The rat CIA models were established by injecting the soluble Pig-Tail Collagen typeⅡ into the left legs of the rat Results The AEBFSS that had been taken orally before causing inflamation could significantly postpone coming on of the rat CIA,droped the incidence of the CIA,and alleviated the rat Arthritis,when...

bjective To investigate the preventive and therapeutic effects of oral AEBFSS on the rat Collagen-Induced Arthritis(CIA) Methods The rat CIA models were established by injecting the soluble Pig-Tail Collagen typeⅡ into the left legs of the rat Results The AEBFSS that had been taken orally before causing inflamation could significantly postpone coming on of the rat CIA,droped the incidence of the CIA,and alleviated the rat Arthritis,when the dose of the AEBFSS amounted to 4 0mg proteins/kg The AEBFSS taken after causing inflamation could ease the rat Arthritis,which would be manifested more evidently after administrating the AEBFSS for 7 days The pathological examinations of the rat joint revealed that the oral AEBFSS was able to significantly ease the CIA rat Arthritis too Analysis showed that the AEBFSS was not only able to reduce the serum anti-C Ⅱantibody, but also inhibit Delayed Type Hypersensitivity(DTH) of the ear in the rat with CIA Conclusions The oral AEBFSS has significant effects of prevention and curing on the rat CIA,the mechanism of which involves T and B lymphocyte immunity simutaneously

探讨大鼠灌胃给予海蛇乙醇浸出物(AEBFSS)对大鼠胶原性关节炎(CIA)的预防和治疗作用。方法用自制的可溶性猪尾Ⅱ型胶原注入实验大鼠左后足造成胶原诱导性大鼠关节炎模型。结果大鼠在致炎前口服AEBFSS,当剂量达含4.0mg浸出蛋白/kg,可明显推迟CIA发病时间,降低CIA发病率和减轻关节炎症状;大鼠发生关节炎后口服AEBFSS,可明显抑制CIA大鼠关节炎症的程度,其作用在用药后7天表现明显;关节组织病理检查表明,口服AEBFSS显著减轻了患鼠关节的炎症程度。初步分析表明,口服AEBFSS既降低了CIA患鼠血清抗CⅡ抗体水平,又对患鼠耳迟发型超敏反应(DTH)产生了明显的抑制作用。结论口服AEBFSS对大鼠胶原性关节炎有显著的防治作用,其机制同时涉及T和B淋巴细胞免疫。

Objective To observe the influences of ligustrazine on the development of rat collagen induced arthritis(CIA) and vascular endothelial growth factor(VEGF).Methods Rats were given intradermal injection of Collagen II to induce CIA,and then different doses of ligustrazine was perfused,and to take cyclosporin A(CSA) as a positive control.The index score and corn thickness of arthritis were detected and joint structure was examined with X ray.The synovial hemoendothelial ultrastructure...

Objective To observe the influences of ligustrazine on the development of rat collagen induced arthritis(CIA) and vascular endothelial growth factor(VEGF).Methods Rats were given intradermal injection of Collagen II to induce CIA,and then different doses of ligustrazine was perfused,and to take cyclosporin A(CSA) as a positive control.The index score and corn thickness of arthritis were detected and joint structure was examined with X ray.The synovial hemoendothelial ultrastructure was observed by transmission electron microscope(TEM)and the expression of synovial VEGF and microvessel density(MVD) were observed by the immunohistochemistry.Result Compared with the model group CSA and 100 mg/kg.d of ligustrazine decreased the index score and corn thickness of arthritis,relieved the lesion of joint structure,improved the synovial hemoendothelial ultrastructure,inhibited the expression of VEGF and reduced MVD of synovium.Conclusion Ligustrazine can inhibit the development of arthritis and lesion of joint structure in CIA rats.The mechanism may be related to the inhibition effect on the expression of VEGF and angiogenesis in synovium.

目的观察川芎嗪对大鼠胶原性关节炎(CIA)炎症发展和滑膜分泌血管内皮生长因子(VEGF)的影响。方法皮内注射Ⅱ型胶原诱导大鼠CIA,给予不同剂量川芎嗪灌胃,以环孢霉素A(CSA)为阳性对照。检测关节炎指数积分和炎症足垫厚度,X摄片检测关节结构,透射电镜观察滑膜毛细血管内皮细胞超微结构,免疫组化观察滑膜VEGF的表达和滑膜微血管密度(MVD)。结果与模型组比较,CSA和100mg/(kg·d)川芎嗪可降低关节炎指数积分和炎症足垫厚度,减轻炎症关节结构的破坏,改善滑膜毛细血管内皮细胞超微结构,抑制滑膜表达VEGF和减少滑膜MVD。结论川芎嗪可抑制CIA大鼠关节炎症发展和关节结构的破坏,其机制与川芎嗪可抑制滑膜表达VEGF、从而抑制滑膜组织血管生成密切相关。

 
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关rat collagen induced arthritis的内容
在知识搜索中查有关rat collagen induced arthritis的内容
在数字搜索中查有关rat collagen induced arthritis的内容
在概念知识元中查有关rat collagen induced arthritis的内容
在学术趋势中查有关rat collagen induced arthritis的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社