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blind method was used
相关语句
  盲法
    Methods: Double blind method was used in observation on effect of DDN and compared with that of Ritalin.
    方法:用双盲法对照研究中药多动宁(治疗组)与西药利他林(对照组)对儿童多动综合征的疗效及副作用。
短句来源
    Methods: Random single blind method was used in clinical study to observe the clinical effect of YZD and compared with that of Ritalin.
    方法 :临床研究采用单盲法随机观察益智丹与利他林的临床疗效 ;
短句来源
    METHODS single blind method was used in observation on effect of ZYYZF and compared with that of Ritalin .
    方法:采用单盲法对比观察中药滋阴益智方(治疗组)与西药利他灵(对照组)对儿童多动症的疗效及副作用。
    METHODS single blind method was used in observation on effect of XFWSZYF and compared with that of Clomipramine .
    方法:采用单盲法对比观察中药宣肺温肾止遗方(治疗组)与氯丙咪嗪(对照组)对儿童非器质性遗尿症的疗效、遗尿消失时间、复发率及不良反应。
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Objective: To study the effect and side effect of Duodongning (DDN), a Chinese herbal preparation, in treating child hyperkinetic syndrome. Methods: Double blind method was used in observation on effect of DDN and compared with that of Ritalin. Results: In the 37 patients treated with DDN, 17 (45.9%) were markedly effective and 16 (43.2%) were effective. In the 33 Patients treated with Ritalin, the respective case numbers were 15 (45.5%) and 14 (42.4%). The Conners Hyperactive Index of the DDN group before...

Objective: To study the effect and side effect of Duodongning (DDN), a Chinese herbal preparation, in treating child hyperkinetic syndrome. Methods: Double blind method was used in observation on effect of DDN and compared with that of Ritalin. Results: In the 37 patients treated with DDN, 17 (45.9%) were markedly effective and 16 (43.2%) were effective. In the 33 Patients treated with Ritalin, the respective case numbers were 15 (45.5%) and 14 (42.4%). The Conners Hyperactive Index of the DDN group before treatment was 2.01±0.83, and after treatment 1.17±0.76,while that of the Ritalin group was 2.07±0.91 before treatment and 1.47±0.79 respectively after treatment. There were no significant difference between the two groups both in effect and in Conner Index, P>0 05. The main side effect was lack of appetite, it revealed in 3 cases of the DDN group and 7 cases of the Ritalin group, and was severer in the latter. Conclusion: The effect of DDN and Ritalin were not different significantly, but the side effect of Ritalin was severer than that of DDN.

目的:探讨中药多动宁治疗儿童多动综合征的疗效及副作用。方法:用双盲法对照研究中药多动宁(治疗组)与西药利他林(对照组)对儿童多动综合征的疗效及副作用。结果:治疗组37例,显效17例(459%),有效16例(432%)。对照组33例,显效15例(455%),有效14例(424%)。Conners多动指数:对照组治疗前为201±083,治疗后为117±076;治疗组治疗前为207±091,治疗后为147±079;两组疗效及多动指数比较均无显著性差异(P>005)。副作用(主要为食欲减退):治疗组有3例,症状较轻;对照组有7例,症状较严重。结论:两组患者临床疗效相似,而副作用利他林高于中药多动宁。

To observe the clinical effect of Yizhidan (YZD) in treating childhood hyperkinetic syndrome (CHS) and its mechanism. Methods: Random single blind method was used in clinical study to observe the clinical effect of YZD and compared with that of Ritalin. The dysmnesia model animal was used to observe the effect of YZD on learning memory function and cerebral monoamine neurotransmitter content. Results: The markedly effective rate and the total effective rate of YZD were 45.56% and 87.78%, which were...

To observe the clinical effect of Yizhidan (YZD) in treating childhood hyperkinetic syndrome (CHS) and its mechanism. Methods: Random single blind method was used in clinical study to observe the clinical effect of YZD and compared with that of Ritalin. The dysmnesia model animal was used to observe the effect of YZD on learning memory function and cerebral monoamine neurotransmitter content. Results: The markedly effective rate and the total effective rate of YZD were 45.56% and 87.78%, which were similar to those of Ritalin (53.33% and 86.67%). The Conners index lowered in both groups, showing insignificant difference (P>0 05). Experimental observation showed that YZD could significantly improve the soft neurologic signs and abnormal encephalogram with less side-effects in comparing with Ritalin (P<0 05). Moreover, YZD could obviously improve the learning memory disturbance induced by scopolamine, sodium nitrite and ethanol, and significantly increased the contents of DA in cerebral tissue, as compared with that of the control group, the difference was significant (P<0 01). It also showed effect on DOPAC, NE, HVA, 5-HT and 5-HIAA of mice in certain degree. Conclusion: YZD is an effective drug in treating CHS, its mechanism might be probably related to the improvement of the memory and the enhancement of DA receptor in cerebral tissue.

目的 :观察益智丹治疗儿童多动症 (CHS)的临床疗效及其作用机制。方法 :临床研究采用单盲法随机观察益智丹与利他林的临床疗效 ;实验研究制作记忆障碍模型 ,观察益智丹对小鼠学习记忆功能和对小鼠脑组织单胺类神经递质含量的影响。结果 :益智丹治疗CHS的显效率、总有效率分别为 4 5 56%、87 78% ,与利他林 ( 53 33%、86 67% )相当 ;Conners指数均明显降低 ,两组间疗效及多动指数比较差异均无显著性 (P >0 0 5)。益智丹还能显著改善患儿软神经征及异常脑电图 ,副反应明显低于利他林组 (P <0 0 1)。对东莨菪碱、亚硝酸钠、乙醇所致的小鼠学习记忆障碍有明显的改善作用 (P <0 0 5) ;且能够显著提高小鼠脑组织多巴胺 (DA)含量 ,与对照组比较差异有显著性 (P <0 0 1) ;对二羟苯乙酸 (DOPAC)、去甲肾上腺素 (NE)、3 甲氧 4 羟基苯乙酸 (HVA)、5 羟色胺 ( 5 HT)、5 羟吲哚乙酸 ( 5 HIAA)也有不同程度的影响。结论 :益智丹是治疗CHS的有效药物 ,其作用机制可能与改善记忆、提高脑组织DA含量有关。

>=OBJECTIVE To study the clinical effect and side-effect of ziyingyizhifang (ZYYZF) , a Chinese herbal preparation , in treating child hyperkinetic syndrome . METHODS single blind method was used in observation on effect of ZYYZF and compared with that of Ritalin . RESULTS In the 42 patients treated with ZYYZF , 19 (45.24%) were markedly effective and 17 (40.48%) were effective . In the 30 patients treated with Ritalin , the respective case numbers were 14 (46.67%) and 12 (40.00%) . The Conners Hyperactive...

>=OBJECTIVE To study the clinical effect and side-effect of ziyingyizhifang (ZYYZF) , a Chinese herbal preparation , in treating child hyperkinetic syndrome . METHODS single blind method was used in observation on effect of ZYYZF and compared with that of Ritalin . RESULTS In the 42 patients treated with ZYYZF , 19 (45.24%) were markedly effective and 17 (40.48%) were effective . In the 30 patients treated with Ritalin , the respective case numbers were 14 (46.67%) and 12 (40.00%) . The Conners Hyperactive Index of the ZYYZF group before treatment was 1.95 ±0.13, and after treatment 1.21 ± 0.44, while that of the Ritalin group was 1.93 ±0.11 before treatment and 1.22 ±0.42 respectively after treatment . There were no significant difference between the two groups both in effect and in Conner Index ( p >0.05 ) ,. The main ADR was lack of appetite , it releaved in 4 cases of the ZYYZF group and 8 cases of the Ritalin group , and was severer in the latter . CONCLUSION The clinical effect of ZYYZF and Ritalin in treating child hyperkinetic syndrome were not different significantly , but the side-effect of Ritalin was severer than that of ZYYZF .

目的:观察中药滋阴益智方治疗儿童多动症的临床疗效及副作用。方法:采用单盲法对比观察中药滋阴益智方(治疗组)与西药利他灵(对照组)对儿童多动症的疗效及副作用。结果:治疗组 42例,显效19例(45.24%),有效17例(40.48%)。对照组30例,显效14例(46.67%),有效12例(40.00%)。 Conners多动指数:治疗组治疗前为1.95±0.13,治疗后为1.21±0.44;对照组治疗前为1.93±0.11, 治疗后为1.22±0.42。两组临床疗效及多动指数比较均无显著性差异(p>0.05)。不良反应:治疗组4 例为轻度食欲减退,对照组8例症状较重,不良反应发生率两组差异具显著性(p<0.05)。结论:滋阴益智方与利他灵治疗儿童多动症的临床疗效相当,而不良反应较少。

 
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