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   gene p 73 的翻译结果: 查询用时:0.201秒
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gene p
相关语句
  p73基因
     Studying progression in gene p73
     p73基因研究进展
短句来源
     Objective To explore the correlation between the gene P73 and the laryngeal squamous cell carcinoma (LSCC).
     目的 探讨P73基因在喉鳞癌中的表达。
短句来源
     Conclusion The gene P73 might not be a target gene in laryngeal carcinogenesis and not play a major role in development of LSCC.
     结论 P73基因可能并非喉癌癌变过程中的靶基因 ,在喉癌的发生发展中可能不发挥重要作用。
短句来源
     Objective As the first relative of p53 gene which is a classic tumor suppressor gene, p73 has the similar structure and function like p53. We study expression of p53 and p73 proteins in epithelial ovarian tumors and its clinical significance.
     目的 p53基因是一个经典的抑癌基因,而p73基因作为p53基因家族的第一个新成员,与p53在结构和功能方面具有很高的相似性。 本研究探讨了p73、p53蛋白在上皮性卵巢肿瘤组织中的表达情况、二者的相互关系及其临床意义。
短句来源
     Gene P 73 was found by Mourad Kaghad in 1997, which shares considerable homology with the tumor suppressor P 53.However, it is unclear whether this protein can operate in a network of development and cell cycle controls as a tumor suppressor.
     P73 基因是Kaghad等在 1997年克隆得到的一个新基因 ,与P53 具有相似的结构、功能与活性 ,但其是否作为一个抑癌基因发挥作用 ,目前尚存在争论。
短句来源
  “gene p 73”译为未确定词的双语例句
     Correlation between the expression of putative protein tyrosine phosphatase,metastasls-associated gene,p73 and the prognosis in patients with lung cancer
     肺癌PTEN、MTA1、p73表达与预后相关性
短句来源
     The positive expression rates of P73 in LSCC tissues, polyps of the vocal cord tissues, paracancerous tissues, and nontypical hyperplasis tissues were 53.06% (26/49), 36.84% (7/19), 41.67% (5/12) and 37.5% (3/8) respectively(P> 0.05 ). The gene P73 was not correlated with the clinical stages and clinical typing of LSCC.
     P73阳性表达率在喉鳞癌组织、声带息肉、癌旁组织及非典型增生组织中分别为 5 3.0 6 % (2 6 / 4 9) ,36 .84 % (7/ 19) ,4 1.6 7% (5 / 12 ) ,37.5 % (3/ 8) ,P73与喉鳞癌的临床分型、分期无相关性。
短句来源
     As one tumor suppressor gene, P73 has its tissular specificity.
     P73作为抑癌基因有其组织特异性。
短句来源
     As one tumor suppressor gene, P73 has its tissular specificity. Cooperative expression of P73 and PCNA protein could be an important index to judge the malignant transformation and clinicopathological process and prognosis.
     P73作为一个抑癌基因,有其组织特异性:P招和PCNA蛋白的协同表达可能是判断胃癌的恶性转化、临床病理过程及预后的重要指标。
短句来源
     Conclusion:Probably high expression of P 73is one hot spot gene alteration of gastric carcinoma and expression of P 73 protein in gastric carcinoma may play an important role during the course of c ancerous development. As one tumor suppressor gene,P 73has its tiss ular specificity.
     结论 :P73高表达可能是一个胃癌发生的热点基因变化 ,基因蛋白 P73在胃癌中的表达对胃癌的发生发展可能起着重要作用 ,P73作为一个抑癌基因 ,有其组织特异性。
短句来源
  相似匹配句对
     OBESE GENE
     肥胖基因
短句来源
     Rescue Gene
     抢救植物基因
短句来源
     On Gene Patenting
     基因的专利问题
短句来源
     The gene of PNGase F from F.
     为了获得大量廉价的N-糖酰胺酶F,本论文研究的主要内容为根据目的基因N-糖酰胺酶F的cDNA序列设计引物,以F.
短句来源
     p73 Gene and Leukemia
     p73基因与白血病
短句来源
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This is the first report of cytogenetic study of flag leaf position in common wheat, Triti-cum aestivum L. F1 and F2 analyses by monosomics and telocentrics indicated that 2D chromosome of Chinese Spring carried at least two genes for pendulous flag leaves, ie. P1 on 2DL and P3 on 2DS; gene (s) E for erect flag leaves on the same chromosome of Xiaoyan No. 6. Gene P1 expressed fully, and P2 partially. Relativizing gene E, P1 and P2 were dominant and recessive...

This is the first report of cytogenetic study of flag leaf position in common wheat, Triti-cum aestivum L. F1 and F2 analyses by monosomics and telocentrics indicated that 2D chromosome of Chinese Spring carried at least two genes for pendulous flag leaves, ie. P1 on 2DL and P3 on 2DS; gene (s) E for erect flag leaves on the same chromosome of Xiaoyan No. 6. Gene P1 expressed fully, and P2 partially. Relativizing gene E, P1 and P2 were dominant and recessive respectively, and vice versa. The chromosome manipulation of these genes was also discussed.

本文首次对小麦旗叶姿态进行了比较系统的细胞遗传学研究。单体、端体的F_1及F_2分析表明:中国春2D染色体上至少有两个旗叶下披基因,即位于2DL上的P_1和2DS上的P_2,前者表达能力很强,后者则较弱,与小偃6号旗叶直立基因共存时分别表现为显性和隐性;小偃6号的旗叶直立基因E也位于2D染色体上,同(P_1+P_2)共存时表现为隐性,仅与P_2共存时则表现为显性。文章还就这些基因的染色体操作等进行了讨论。

Allelotype and point mutation of p53 exon 7 were detected in 45 pairs of primary hepatocellular carcinoma (PHC) by restriction fragment length polymorphism (RFLP) and polymerase chain reaction (PCR). Thirty -one gene markers covered 14 chromosomes were used including suppressor genes p53 and RB1. The results showed 19 gene markers covered 8 chromosomes revealed loss of heterozygosity. Six of 28 informative cases showed loss on 6q21 using probe pJCZ30, which had not been reported before....

Allelotype and point mutation of p53 exon 7 were detected in 45 pairs of primary hepatocellular carcinoma (PHC) by restriction fragment length polymorphism (RFLP) and polymerase chain reaction (PCR). Thirty -one gene markers covered 14 chromosomes were used including suppressor genes p53 and RB1. The results showed 19 gene markers covered 8 chromosomes revealed loss of heterozygosity. Six of 28 informative cases showed loss on 6q21 using probe pJCZ30, which had not been reported before. The allele loss was low frequent on the other chromosomes including p53 and RBI.Fourty-five cases of PHC from areas of low aflatoxin Bl (AFB1) exposure but high risk to HBV were examined for identifying point mutation of p53 exon 7 by PCR and restriction enzyme analysis using Rsa Ⅰ, Msp Ⅰ, Hae Ⅲ site at codon 229, 247 and 249, respectively. Two of 45 cases showed point mutation at codon 247 and 249, respectively. Our results indicated that changes of molecular genetics on PHC is a complex event, and there are multiple steps, and multiple genes are involved in hepatocarcinogenesis. Meanwhile, the results supported the postulated role of AFB1 together with HBV in the generation of specific mutation of the p53 gene provide evidence to suggest that HBV infection alone-or exposure to AFB1 alone do not contribute to these base changes.

作者应用Southern杂交和PCR扩增技术,分析了45例配对的原发性肝癌及其癌旁肝组织的等位基因型和p53第七外显子的突变状况.共应用了位于14对染色体的31个基因标志,结果在8对染色体的19个基因位点出现不同程度的杂合型丢失(LOH),丢失频率3.2%~23.5%.其中第6对染色体的pJCZ30位点的LOH为首次报告.应用PCR扩增后限制性酶切,分析了p53第七外显子的229,247和249三个密码子,结果仅2例癌组织分别在247和249密码子出现点突变.本实验结果表明,原发性肝癌的分子遗传学变化是复杂的,不同原因(HBV,黄曲霉毒素)相关的原发性肝癌,其等位基因的变化和LOH的频率存在差异,特别是p53基因第249密码子的特征性点突变差别显著,说明原发性肝癌的发生是一多基因变化,多步骤的过程.

24 female Goats were superovulated with Gonadotrophins. About 48h after first mating,total 155 ova were recovered from 16 stimulated donors. The ova recovery rate was 79.08%(155/196).The average number of ova produced by per donor was about 12.25%(196/16). Pronuclei or nuclei in atotal of 65 one-celled zygotes and 29 two-four cell stage embryos were visualized under Normarski IC microscope, and microinjected with Human Growth Hormone Gene(p~(SMGHI)/BamHI) respectively. 91 injected zygotes and embryos...

24 female Goats were superovulated with Gonadotrophins. About 48h after first mating,total 155 ova were recovered from 16 stimulated donors. The ova recovery rate was 79.08%(155/196).The average number of ova produced by per donor was about 12.25%(196/16). Pronuclei or nuclei in atotal of 65 one-celled zygotes and 29 two-four cell stage embryos were visualized under Normarski IC microscope, and microinjected with Human Growth Hormone Gene(p~(SMGHI)/BamHI) respectively. 91 injected zygotes and embryos were transferred surgically into 14 synchronized recipients. After embryotransfer, 7 recipients became pregnant, and total 12 lambs were born, 11 alive and one dead at parturition.The frequency of hGH integration was examinated by using DNA probes labeled with NonradioactiveDigoxigenin. Results showed that 4 in 12 tested lambs carried the foreign genes, the integration frequencywas 33.33%(4/12). Gene expression in 4 living lambs (2 hGH gene integration positive, 2 negative) wasdetected by ELISA, and no one exprcsscd humane Growth Hormone in plasma.

对24头供体山羊进行超数排卵处理,16头超排有效。在第1次配种后48h左右取卵,共收集到卵155个。回收率79.08%(155/16)。平均每头供体排卵12.25个(196/16)。在Normarski干涉相差显微镜下观察65个单细胞受精卵及29个2~4细胞期胚胎的原核及细胞核,并分别注射人生长激素基因(p~(SMGHI)/BamHI),其中91枚移植到经同期发情处理的14头受体中。结果7头妊娠,共产活羔11头,死胎1头。经用Digoxigcnin标记核酸探针对转移基因羊检测,4头整合了外源基因。整合频率为33.33%(4/12)。采用酶联免疫吸附法(ELISA)对仍存活的2头未整合、2头整合羊检测是否表达外源基因,全为阴性。

 
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