This paper mainly deals with the problems raised in tumor hyperthermia,with only a few measured temperatures to carry out the parameter identification for reconstruction temperature fields.
These results provide the experimental foundation for the new noninvasive method of blood perfusion estimation, which can have significant applications in future clinical practices, such as tumor hyperthermia using ultrasound, radio frequency or laser.
Conclusions Our results show that the selfprepared nanosized F 2O 3 is a kind of high biocompatibility materials and perhaps is suitable for further application in tumor hyperthermia.
Tumor hyperthermia is a rediscovered technique of oncotherapy which has confirmed value in many studies on cell cultures, rodent and mammalian tumors as well as first investigations on patients with tumors.
Local tumor hyperthermia (42-43°C) during moderate whole body hyperthermia (40°C) and hyperglycemia (5 ? 10-3 g ml-1) led to an amplification of tumor hyperacidification of ΔpH = -0,47 ± 0,19 in 12 from 20 animals.
A nwe method for identification of the temperature-dependant thermal conductivity coefficient K、thermal diffusion coefficient、blood perfusion rate Wb and metabolic rate Qm is presented. In this paper, the discussion is mainly about this condition: the above mentioned coefficients are linearly dependant with temperature change. For more complex case, such as simultaneous space and temperature-dependant problems can be solved by the same method.This method is not limited by the number of unknown parameters. A...
An insulated,water-cooled dipole radiating in a biological tissue,is ana-lyzed with a theoretical electromagnetic model. The specific absorption rate-SAR and tem-perature distribution patterns are calculated taking into account the effect of the water flow-ing inside the applicator,and compared with the temperature distribution of no-water-cooledradiating dipole. The numerical caculated results are comformed with the equivalent musclephantom experiment.It has been shown that , the temperature distribution w...
A new technique was postulated to measure the space-dependent conductivety( K ), blood perfusion rate( W b), metabolic rate( q m), and thermal diffusivity ( α ) in Pennes' bioheat equation, thus overcomes the shortcoming of classical approaches , in which only the constant parameters( K,W b, α ) but q m could be obtained. The over-determined equations were solved by using Householder's transformation. In order to noninvasively measure the subcutaneous temperature, the variational principl...