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spondylitis as
相关语句
  相似匹配句对
     Ankylosing spondylitis
     强直性脊柱炎
短句来源
     Ankylosing Spondylitis and Osteoporosis
     强直性脊柱炎与骨质疏松的研究
短句来源
     EXTRASPINAL MANIFESTATION OF ANKYLOSING SPONDYLITIS
     强直性脊柱炎的脊柱外表现
短句来源
     Typhoid spondylitis:one case
     伤寒性脊柱炎1例
短句来源
     Peripheral Arthropathy of Ankylosing Spondylitis (AS)
     强直性脊柱炎的外周关节病
短句来源
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  spondylitis as
Inflammatory low back pain, spinal involvement and sacroiliitis are key features of both brucellosis and ankylosing spondylitis (AS).
      
This study was performed to investigate the relationship between functional disability and depression in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS).
      
The SpA are a cluster of inflammatory arthridites encompassing ankylosing spondylitis (AS), psoriatic arthritis (PsA), Reiter's syndrome/reactive arthritis (ReA), and the arthritis associated with inflammatory bowel disease.
      
Ankylosing Spondylitis (AS) is probably the best studied of these disease.
      
Ankylosing spondylitis (AS) is a chronic systemic rheumatic disease that primarily affects the sacroiliac joints and spine.
      
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The clinical pictures of ankylosing spondylitis ( AS)were analyzed in 157 patients. It was found that AS occurs more frequently between 15 to 30 years of age, being more prevalent in men than in women. The incidence ratio of male to female was 14.7:1. Approximately 23.6% of patients had a positive family history with the disease. The initial joint involvement was usually located in the hip ( 33.1%) , lumbar spine ( 24.2% ) and sacroiliac joints ( 21 .7% ) , and the spine and sacroiliac joints are predominatly...

The clinical pictures of ankylosing spondylitis ( AS)were analyzed in 157 patients. It was found that AS occurs more frequently between 15 to 30 years of age, being more prevalent in men than in women. The incidence ratio of male to female was 14.7:1. Approximately 23.6% of patients had a positive family history with the disease. The initial joint involvement was usually located in the hip ( 33.1%) , lumbar spine ( 24.2% ) and sacroiliac joints ( 21 .7% ) , and the spine and sacroiliac joints are predominatly affected. The definite diagnosis of AS requires X-Ray evidence of unilateral or bilateral sacroiliitis, presence of pain at the dorsolumbar junction or in the lumbar spine with stiffness, progressive limitation of motion of the spine, limitation of chest expansion to less than 2.5cm and HLA-B2v positive and rheumatoid factor ( RF ) negative.

本文对157例强直性脊柱炎患者进行了临床分析。认为AS多初发于15—24岁之间的男性青年,男女发病比例为14.7:1。有23.6%的病人有家族史。初发关节多在髋关节(33.1%)、腰椎(24.2%)及骶髂关节(21.7%);受累关节以骶髂关节及脊柱为主。对AS的诊断必须有经X线摄片证实的单侧或双侧骶髂关节炎,并有腰背部疼痛和僵硬,脊柱活动进行性障碍,胸扩度少于2.5cm及HLA—B_(27)阳性,RF阴性.

Ankylosing spondylitis (AS)was used to be considered as a central type of rheumatoid athritis. According to the study on HLA-B_(27) and the clinical manifestations of AS,AS is considered to be an independant ent- ity.Our study showed that AS is often seen in young people and has a marked hereditary tendency.In the 40 patients,the positive rate of HLA-B_(27) was 90%.18 brothers or sister of 7 HLA-B_(27) positive AS patients were in- vestigated.10 cases had suffered from AS.The incidence was 56%.By exam-...

Ankylosing spondylitis (AS)was used to be considered as a central type of rheumatoid athritis. According to the study on HLA-B_(27) and the clinical manifestations of AS,AS is considered to be an independant ent- ity.Our study showed that AS is often seen in young people and has a marked hereditary tendency.In the 40 patients,the positive rate of HLA-B_(27) was 90%.18 brothers or sister of 7 HLA-B_(27) positive AS patients were in- vestigated.10 cases had suffered from AS.The incidence was 56%.By exam- ination of two D and doppler echocar- diography in 22 patients with AS,it was found,one case with aortic nonc- oronary valvular ring and thickness of valvular leaf,3 cases with slight en- largement of left ventricle and 2 cases with pericardial effusion.In 14 of 18 AS patients,their urine tests were abnormal by detection with SDS-PAGE method.In the chest film of one patient,fibrosis with spot shadow was found in upper parts of both left and right lungs.The pulmonary fun ction of 10 patients was abn ormal in 14 AS patients.Dysfunction of diffusion was especially prominent.

强直性脊拄炎(AS)曾被认为是中心型类风湿关节炎,由于人类组织相关抗原(HLA)的研究进展及 AS 的许多临床表现的研究,证明该病应为一独立的疾病。本文对40例 AS 患者的 HLA 及部分患者骨骼外脏器受损情况进行了研究,证明本病多为青年起病,有明显遗传倾向,患者中 HLA-B27阳性者占90%。7例 HLA-B27阳性患者同一亲代共18例的调查中,10例可确诊为 AS,发病率达56%。随机选择22例行二维超声心动图及多普勒检查,发现1例主动脉无冠瓣环及瓣叶轻度增厚,3例左室内径轻度增大,2例有心包积液。18例行尿十二烷基磺酸钠二聚丙烯胺电泳(SDS-PAGE)测定,14例异常,占77%,以肾小管受损为主。40例患者的胸相中,1例有双上肺纤维化,伴斑点状阴影。14例行肺功能测定患者中,10例异常,占71%,以弥散功能障碍为主。

The link between HLA-B27 and clinical features and immunological changes was studied in 67 cases of patients with ankylosing spondylitis(AS) . The results s howed that the age of onset in HLA- B27 positive AS was 5 years earlier than that in HLA- B27 negative AS (P(?) 0.05); Iridocyclitis and acute conjunctivitis were noted in 17.2% of HLA- B27 positve patients with AS: Serum level of IgG, IgA, IgM and γ-globulin obviously elevated in HLA- B27 positive AS. It was suggested that the pathogenesis of ankylosirg...

The link between HLA-B27 and clinical features and immunological changes was studied in 67 cases of patients with ankylosing spondylitis(AS) . The results s howed that the age of onset in HLA- B27 positive AS was 5 years earlier than that in HLA- B27 negative AS (P(?) 0.05); Iridocyclitis and acute conjunctivitis were noted in 17.2% of HLA- B27 positve patients with AS: Serum level of IgG, IgA, IgM and γ-globulin obviously elevated in HLA- B27 positive AS. It was suggested that the pathogenesis of ankylosirg spondylitis together with eye involvement as well as the enhancement of humoral immune responses in AS be closely related to HLA- B27.

我们研究了67例强直性脊柱炎(AS)患者的临床特点及免疫学变化与HLA-B_(27)的关系。结果表明,HLA-B_(27)阳性AS患者的发病年龄较HLA-B_(27)阴性者平均早5年(P<0.05);HLA-B_(27)阳性的AS患者中17.2%并发虹膜睫状体炎或急性结膜炎;HLA-B_(27)阳性患者血清IgG、IgA、IgM及γ-球蛋白水平明显增高。提示AS患者的发病、眼部损害及体液免疫反应增强均与HLA-B_2密切相关。

 
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