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wild p
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  野生型p53
     Overexpression of HER2/neu downregulates wild p53 protein expression via PI3K and Ras/RaE/ MEK/ERK pathways in human breast cancer cells
     乳腺癌细胞过表达HER2/neu时经PI3K和Ras/Raf/MEK/ERK信号通路下调野生型p53蛋白含量
短句来源
     Presentation of growth retardation and apoptosis in the wild p53 transduced K562 cells
     转导野生型p53的K562细胞出现生长抑制和凋亡
短句来源
     Conclusion suggested that the wild p53 could promote growth retardation and apoptosis of K562 cells.
     结论提示,野生型p53可促进p53表达阴性的K562细胞生长抑制与凋亡。
短句来源
     Objective To investigate the effect of HER2/neu overexpression on the wild p53 gene expression, cell proliferation and sensitivity to γ irradiation via phosphatidylinositol 3 kinase (PI3K) pathway in human breast cancer cell MCF7. Methods Lipofectin mediated gene transfection method was used to transfer HER2/neu into MCF7 cells.
     目的研究HER2/neu基因过表达通过磷脂酰肌醇3激酶(PI3K)通路对乳腺癌细胞MCF7野生型p53基因表达、细胞增殖及对γ射线照射敏感性的影响。 方法以脂质体介导的HER2/neu基因转染MCF7细胞,用G418筛选阳性克隆。
短句来源
     \ (2)The expression of p21\+\{WAF1/CIP1\} in PTC is induced by wild p53\|protein, which serve as a regulative route during carcinogenesis and development of PTC.
     (2 )在 PTC的发生、发展中存在依赖野生型 p5 3蛋白诱导P2 1WAF 1 /CIP1表达的途径
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  “wild p 53”译为未确定词的双语例句
     The upgrading of atypia link with decrea sed expression of wild p53 485mRNA(mild:55.6%;medium:41.7%;severe:26.1%)and increased expression of the muta nt p53protein(mild:11.1%;medium:25.0%;severe:34.8%).
     p53mRNA在乳腺导管非典型增生组织中的表达随着异型性的增加而下降(轻度:55.6%;中度:41.7%;重度:26.1%),而p53蛋白则相应增加(轻度:11.1%;中度:25.0%;重度:34.8%)。
短句来源
     When treated with LY294002 or U0126 for 24 hours, the amount of wild p53 protein in MCF7-neu3 cells was 1. 7 or 1. 5 times higher than those in DMSO treated cells.
     在经PI3K信号通路抑制剂LY294002及MEK抑制剂U0126处理24 h后,MCF7-neu3细胞p53蛋白含量分别上升了1.7和1.5倍(P<0.01),在LY294002和U0126处理48 h后,p53蛋白含量分别升高了4.7倍和5.3倍(P<0.01)。
短句来源
     HepG2 and Lovo cell lines (wild p53) were transfected with p53 antisense ODN to detect the expression of wnt signaling pathway and wnt inhibitor FrpHE and DKK-1 after p53 were blocked.
     并且在不同p53状态的人肝癌、大肠癌、神经胶质瘤细胞株中(U251,p53突变)加入化疗药物后,以RT-PCR技术检测Wnt通路抑制剂FrpHE mRNA和DKK-1 mRNA的表达水平,明确化疗药对Wnt通路抑制剂FrpHE和DKK-1的调节作用。
短句来源
     Objective To investigate expression of HCV core protein, mutant p53,Bcl_2 proteins and explore correlation of these three proteins expression in the tissues of HCC; to explore wether HCV core protein promote wild p53 to mutation p53 and Bcl_2 protein expression.
     目的探讨HCC组织中的核心蛋白、突变p53、Bcl_2的表达以及其相关性,探讨HCV核心蛋白是否促进p53突变和Bcl_2的表达。
短句来源
     Effect of exogenous wild P53expression on sensitization to chemotherapeutic agents in human lungl cancer cells and cloning of related genes
     外源Wtp53表达对人肺癌细胞药物敏感性影响及相关基因克隆
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  相似匹配句对
     Inner Wild
     内敛的狂野
短句来源
     WILD AT HEART
     我心狂野
短句来源
     ALASKA-SPIRIT OF THE WILD
     阿拉斯加:原始之魂
短句来源
     Wild Animals on the Plateau
     高原精灵
短句来源
     temperature 53℃.
     温度53℃。
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  wild p
In this study, we examined the induction of apoptosis and the role of caspases in 5-FC/CD gene therapy using human malignant glioma cells [Gli36Δ5 (mutated p53) and U87MG (wild p53)].
      
p21 expression was seen in 15 of 26 mutant p53-positive and 2 of 4 wild p53-positive tumors.
      


P. fucata (Gould) and P. chemnitzi (Philippi) are two major species of pearl oysters. And Hepu, Guangxi Province, has been the producing area of world famous pearls-"Nanzhu" since ancient times. With the objective of genetic improvement and selective breeding of the pearl oysters, genetic variation has been assayed by starch gel electrophoresis at 8-13 loci in the wild population of P. fucata and P. chemnitzi sampled from the Hepu coast, the gulf of Beibu, as well as the cultured population...

P. fucata (Gould) and P. chemnitzi (Philippi) are two major species of pearl oysters. And Hepu, Guangxi Province, has been the producing area of world famous pearls-"Nanzhu" since ancient times. With the objective of genetic improvement and selective breeding of the pearl oysters, genetic variation has been assayed by starch gel electrophoresis at 8-13 loci in the wild population of P. fucata and P. chemnitzi sampled from the Hepu coast, the gulf of Beibu, as well as the cultured population of P. fucata at a pearl culture ground. The latter one was produced by artificial hatchery from wild individuals.The average number of allele observed per locus in P. fucata was 2.63 and in P. chemnitzi 2.15. The frequency of polymorphic loci (P<0.99) was 0.750 and 0.692 respectively. The average heterozygosity (0.223) of cultured P. fucata was nearly twice as high as that (0.113) of wild P. fucata which was closely similar to that (0.157) of wild P. chemnitzi.The genetic identity and genetic distance between wild and cultured P. fucata was 0.992 and 0.008, whereas those between wild P. fucata and wild P. chemnitzi was 0.252 and 1.379 respectively.The deficits of heterozygotes were observed in these three samples of the two species studied. It is suggested that natural selection and Wahlund effect could account for these deficits.

用淀粉凝胶电泳测定了养殖合浦珠母贝以及野生合浦珠母贝和长耳珠母贝的8—13个蛋白和同工酶座位的遗传变异。合浦珠母贝每个座位观察到的平均等位基因数为2.63,而长耳珠母贝为2.15。它们多型座位(P≤0.99)的比例则分别为0.750和0.692。由野生贝经人工育苗繁育出来的养殖合浦珠母贝的平均杂合度比野生合浦珠母贝的高近一倍(0.223和0.113),而野生合浦珠母贝和野生长耳珠母贝的平均杂合度水平相近(0.113和0.157)。两个合浦珠母贝群体相比较遗传相似度(Ⅰ)和遗传距(D)为0.992和0.008,野生合浦珠母贝和野生长耳珠母贝相比较为0.252和1.379。 两个种的三个群体样本中都有杂合子缺失现象,这可能是由自然选择和Wahlund效应所引起的。

Residual spraying to control Phlebotomus chinensis with deltamethrin was applied to all field caves and 13-14 villages within the radius of 10 km2 surrounding Yunyan town in 1985-1986. The dosage used was 25 mg/m2 in field caves and livestock caves and 12.5 mg/m2 in villages. The test area covered 74000 m2. In 1985, after spraying, sandfly density decreased to very low level until the end of sandfly season. However, it was still very high in unsprayed field caves throughout the sandfly season.Three and a half...

Residual spraying to control Phlebotomus chinensis with deltamethrin was applied to all field caves and 13-14 villages within the radius of 10 km2 surrounding Yunyan town in 1985-1986. The dosage used was 25 mg/m2 in field caves and livestock caves and 12.5 mg/m2 in villages. The test area covered 74000 m2. In 1985, after spraying, sandfly density decreased to very low level until the end of sandfly season. However, it was still very high in unsprayed field caves throughout the sandfly season.Three and a half months after spraying, sandfly specimens were collected and forced to contact the intact sprayed wall surface. The first knock-down time was between 33 to 61. minutes. However, contact with poorly sprayed wall surface gave a longer knock-down time between 75 and 305 minutes.In 1986, after spraying, the sandfly densities were markedly decreased as compared with the same months in the previous year. In June in the unsprayed area the sandfly density decreased by 79.1% in field caves and 71.5% in livestock caves of village. In August, the sandfly density decreased by 46.9% in the field caves and 59.6% in village area. The results showed that the residual potency effect of deltamethrin was long enough to suppress sandfly density throughout the sandfly season (3.5 to 4 months).Deltamethrin spraying (25 mg/m2) in field caves and livestock caves before or at the beginning of sandfly season, was effective and practical in the control of peri-wild P. chinensis in the loess plateau of northern Shaanxi.

1985~1986年,在陕北宜川县云岩镇方圆10km~2内400余个野外洞穴和13~14个自然村进行溴氰菊酯杀灭近野栖中华白蛉方法的研究.两年喷洒总面积达74 000m~2。经喷洒野外洞穴和村内畜窑相结合的处理措施,1986年6和8月,野外对照洞穴的白蛉密度比1985年同期分别下降79.1%和46.9%,村内对照畜窑分别下降71.5%和59.6%.连续两年的喷洒实验结果表明,野外洞穴喷洒溴氰菊酯结合村内畜窑喷洒的方法是防治陕北黄土高原近野栖中华白蛉的有效方法。

The fatty acid composition of prawn (Penaeus chinesis) was similar to that in other marine animals, palmitic acid(16:0) and n-3 polyunsaturated fatty acids (20:5n-3, 22:6n-3) predominating in both male and female. The major fatty acids of the hepatopancreas of wild P. chinensis were 16:0 (20. 0-22. 5%), 16:1(9.9-10.1%), 18:0(2.5-2.9%), 18:1n-9 (12.3-14. 0%),18:2n-6(2.4-2.6%), 20:5n-3(6. 1-6. 6%) and 22:6n-3(7. 1-7. 5%). Muscle had almost the same profile. Cultured P. chinensis major fatty acids were...

The fatty acid composition of prawn (Penaeus chinesis) was similar to that in other marine animals, palmitic acid(16:0) and n-3 polyunsaturated fatty acids (20:5n-3, 22:6n-3) predominating in both male and female. The major fatty acids of the hepatopancreas of wild P. chinensis were 16:0 (20. 0-22. 5%), 16:1(9.9-10.1%), 18:0(2.5-2.9%), 18:1n-9 (12.3-14. 0%),18:2n-6(2.4-2.6%), 20:5n-3(6. 1-6. 6%) and 22:6n-3(7. 1-7. 5%). Muscle had almost the same profile. Cultured P. chinensis major fatty acids were similar except that levels of 18:2n-6(6. 3-13. 0%) were higher and 16:1(3. 6-4. 2%)low-er. It was found that wild prawn had higher levels of n-3 and lower levels of n-6, unsaturated fatty acids but the cultured one had lower levels of n-3 and higher levels n-6. The n-3/n-6 ratio of the wild prawn was also higher than that of the cultured one.

野生中国对虾(Penaeus chinensis)脂肪酸的组成类似于其他的海洋动物,即雌、雄虾的肝胰脏和肌肉中,棕榈酸(16:0)和n-3族高不饱和脂肪酸(如20:5n-3和22:6n-3)占优势。野生虾体内含有的脂肪酸种类,尤其是高不饱和脂肪酸的种类多于养殖虾。野生虾肝胰脏中主要脂肪酸为16:0(20.0~22.5%),18:0(2.5~2.9%),18:1 n-9(12.3~14.0%),18:2 n-6(2.4~2.6%),20:5 n-3(6.1~6.6%)和22:6 n-3(7.1~7.5%)。肌肉中的主要脂肪酸种类大致与肝胰脏中相同。养殖虾中除了18:2 n-6(6.3~13.0%)高于和16:l(3.6~4.2%)低于野生虾外,其余的基本类似。野生虾比养殖虾有较高水平的n-3族和较低水平的n-6族不饱和脂肪酸,且野生虾n-3/n-6族脂肪酸的比率同样大于养殖虾。

 
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