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cmv-hepatitis
相关语句
  cmv肝炎
    Methods The levels of serum IL-12, IL-18 and TNF-α in 36 in fants with CMV-hepatitis before and after treatment and in 21 normal infants we re detected by enzyme-linked immunosorbent assay.
    方法采用酶联免疫吸附法检测36例CMV肝炎患儿治疗前后及21例健康婴儿血清IL1-2、IL-18及TNF-α的水平。
短句来源
    Results Serum levels of IL-12, IL-18 and TNF-α in infants with CMV-hepatitis were obviously higher than those in normal infants(P< 0. 001) and had a positive correlation with alanine aminotransferase(ALT) respect ively(P< 0.01).
    结果CMV肝炎患儿血清中IL-12、IL-18及TNF-α的水平明显高于正常对照组(P<0.001),且均与血清丙氨酸转氨酶(ALT)显著正相关(P<0.01);
短句来源
    Conclusion In the infants with CMV-hepatitis, the levels of serum IL-12, IL-18 and TNF-α are assisted markers for estimating activity of i nflammation and degree of liver damage and have great values in predicting e ffects of treatments.
    结论血清IL-12、IL-18及TNF-α的检测可作为婴儿CMV肝炎炎症活动性和肝损害程度的评判指标,并对预测药物抗病毒疗效有重要的指导价值。
短句来源
    Methods The levels of serum IL-18 and TNF-α in 36 infants with CMV-hepatitis before and after treatment and in 21 normal infants were detected by enzyme linked immunosorbent assay (ELISA).
    方法采用酶联免疫吸附法(ELISA)检测36例CMV肝炎患儿治疗前后及健康婴儿21 例血清IL-18和TNF—α水平。
短句来源
    Conclusion In the infants with CMV-hepatitis, the levels of serum IL-18 and TNF-α are assisted markers for estimates of activity of inflammation and degree of damage of livers and have great values in predicting effects of treatments.
    结论血清IL-18及TNF—α检测可作为婴儿CMV肝炎炎症活动性和肝损害程度的评判指标,并对预测药物抗病毒疗效有重要指导价值。
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This paper reviewes some climical cultures about thcctiology, particularities and complications of infant hepatitis syndrome in 12 years in our country. In which, there are variant percentage and variant clinical manifes tations of virus hepatitis, CMV hepatitis and bacteria infection or toxic hepatitis etc.

本文综述了国内12年来有关婴儿肝炎综合征的病因、特点及并发症的临床研究论述,阐明病毒性肝炎、巨细胞病毒感染及细菌感染中毒性肝炎等在其中所占的不同比例,临床特点亦各有不同。

In order to investigate the etiology . pathologic changes of congenital biliary atresia (CBA) and the relations of its prognosis with the infection of cytomegalovirus (CMV ) , 14 cases with CBA including those associated with CMV hepatitis are studied. The liver tissues and lymph nodes of porta hepatis obtained through operation were -both detected of CMV by polytnerase chain reaction (PCR-CMV-1DNA ) and examined microscopically with HE stain. Eight being PCR-CMV- 1DNA positive meant the incidence of CMV infection...

In order to investigate the etiology . pathologic changes of congenital biliary atresia (CBA) and the relations of its prognosis with the infection of cytomegalovirus (CMV ) , 14 cases with CBA including those associated with CMV hepatitis are studied. The liver tissues and lymph nodes of porta hepatis obtained through operation were -both detected of CMV by polytnerase chain reaction (PCR-CMV-1DNA ) and examined microscopically with HE stain. Eight being PCR-CMV- 1DNA positive meant the incidence of CMV infection was 57. 1% . The pathological changes in CBA and the degree of hyperplasia of bile ducts correlated with the increase of patients, age. There was no significant difference in cholestasis , liver cell necrosis , and giant cell changes between CMV positive group and negative group. Liver fibrosis was obviously remarkable in CMV negative group , but the necrosis of liver was severe in CMV positive group. On following-up of 8-20 months . 5/6 cases survived in CMV positive group. Conclusion , Some of CMA might be a causative factor and. give rise to a better prognosis of CBA.

为了探讨先天性胆道闭锁(CBA)的原因,分析肝脏病理变化、临床预后与巨细胞病毒(CMV)感染的关系。取14例CBA患儿术中肝脏及肝门淋巴结标本,一份进行多聚酶链反应巨细胞病毒基因(PCR-CMV-DNA)检测,另一份肝脏标本做HE染色光镜检查。结果:14例中CMV阳性占8例。肝脏病理检查表明随手术时日龄增加,胆管增生明显。比较CMV阳性组与CMV阴性组肝细胞病变、淤胆无差异,肝纤维化CMV阴性组重于阳性组;肝细胞坏死CMV阳性组重于阴性组。随访8~20个月,生存6例,其中CMV阳性5例,死亡8例。CMV感染可能是CBA的病因之一,肝纤维化程度、术后胆管炎发生的频率和程度与预后关系密切。从临床归转看CMV感染阳性组预后较好。

In order to study the clinical characteristics and changes of the immune function in infant suffered from cytomegalovirus (CMV) hepatitis,we divided 39 infants suffered from CMV hepatitis into two groups (congenital infection and perinatal period infection),compared the main clinical manifestation and laboratory data of one group with another group, and detected their immune function of various clinical stagesResult:In comparision of the congenital infection of CMV with perinatal period infection of CMV,the...

In order to study the clinical characteristics and changes of the immune function in infant suffered from cytomegalovirus (CMV) hepatitis,we divided 39 infants suffered from CMV hepatitis into two groups (congenital infection and perinatal period infection),compared the main clinical manifestation and laboratory data of one group with another group, and detected their immune function of various clinical stagesResult:In comparision of the congenital infection of CMV with perinatal period infection of CMV,the symptom of congenital infection group was more obvious,total bilirubin and conjugated bilirubin,γ-GT were higher,prothrombin time was more lengthened,the motelity and the incidence of congenital malformation were higher the cellular immunity function of all payients of CMV hepatitis were damagedConclusion:we should pay attention to monitoring CMV infection in gravida so as to reduce the incidence of CMV infection and raise the quality of population

为研究婴儿巨细胞病毒(CMV)肝炎的临床特点及免疫功能变化,将39例婴儿CMV肝炎病人分为先天感染组及围生期感染组,对二组主要临床表现及实验室检查结果进行比较;并对39例患儿不同临床期的细胞免疫功能进行检测。结果:先天感染组的症状较围生期组重,总胆红素、结合胆红素、PT及γ-GT均较围生期组高,病死率及先天畸形发生率亦明显高于围生期组;CMV肝炎患儿细胞免疫功能受损。结论:应重视孕期的CMV感染监测,以降低CMV感染的发病率,提高人口素质。

 
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