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obese women
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  肥胖妇女
    Spectrum of NAFLD and diagnostic implications of the proposed new normal range for serum ALT in obese women
    新提出的肥胖妇女血浆中ALT正常范围的NAFLD疾病谱与诊断意义
短句来源
    BODY FAT DISTRIBUTION AND CARDIOVASCULAR DISEASE AND DIABETES MELLITUS RISK FACTORS IN PRE-AND POST-MENOPAUSAL OBESE WOMEN WITH SIMILAR BMI
    肥胖妇女绝经前后体脂分布及心血管病、糖尿病危险因素探讨
短句来源
    Clinical investigation about the effect of rosiglitazone on fourty-two overweight/obese women with menstrual disorders
    罗格列酮治疗42例超重/肥胖妇女月经紊乱的临床观察
短句来源
    Objective:To study the body fat distribution,cardiovascular disease and diabetes mellitus risk factors in pre and post menopausal obese women.
    目的 :观察绝经前后肥胖妇女体脂分布及心血管病、糖尿病的危险因素变化。
短句来源
    Objective:To observe the therapatic effect of rosiglitazone on overweight/obese women with menstruation disorder, and to explore the potential mechanism.
    目的:观察罗格列酮对超重/肥胖妇女月经紊乱的治疗效果,并对其机制进行初步探讨。 方法:42例已排外其他可引起月经紊乱的疾病且存在高胰岛素血症的超重/肥胖伴月经紊乱妇女,给予罗格列酮4~8mg/天治疗6个月。
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  “obese women”译为未确定词的双语例句
    In postmenopausal obese women ,the ISI showed positive correlation with IGFBP-1(P<0. 01) and SHBG(P<0. 01) .
    ISI,IGFBP-1,SHBG明显降低(P<0.01)。
短句来源
    WHR or TC or LDL and FPG were significantly increased and the SHBG were significantly decreased (P<0. 01) in postmenopausal obese women than in pre-menopausal obese women (P<0. 01).
    多元逐步回归分析显示绝经后肥胖女性ISI与IGFBP-1(β=0.202,P=0.003)和SHBG(β=0.138,P=0.003)呈正相关。
短句来源
    The FTI were significantly higher and ISI or IGFBP-1 or SHBG were significantly lower (P<0. 01 ,P<0. 01 ,P<0. 05) in pre-menopausal obese women than in pre-menopausal nonobese women.
    ④与绝经前非肥胖女性比较,绝经后非肥胖女性空腹免疫反应性胰岛素、胰岛素原水平明显升高(P<0.01),SHBG明显降低(P<0.01)。
短句来源
    The FTI were significantly higher and ISI or IGFBP-1were significantly lower in postmenopausal obese women than in postmenopausal nono-bese women (P<0. 01).
    ⑤与绝经前非肥胖女性比较,绝经前肥胖组女性空腹真胰岛素明显升高(P<0.05),ISI,IGFBP-1,SHBG明显降低(P<0.of,P<0.01,P<0.05)。
短句来源
    Conclusions ISI were positively correlated with serum IGFBP 1 and SHBG in postmenopausal obese women.
    ⑤与绝经后非肥胖组比较,绝经后肥胖组真胰岛素水平明显升高(P<0.01),ISI,IGFBP-1明显降低(P<0.01)。
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  obese women
Body fat distribution, blood pressure and blood glucose in Egyptian obese women undergoing a weight control program
      
Genotype-by-nutrient interactions assessed in European obese women
      
Objective Since idiopathic intracranial hypertension (IIH) is most prevalent in obese women of childbearing age, concerns arise regarding the impact of pregnancy on the disorder and the potential teratogenicity of some therapeutic agents.
      
___TAGSTART___BR___TAGEND___Methods: Tenderness was quantitatively assessed using point count of 18 tender points and by dolorimetry thresholds in 54 obese women (BMI >amp;gt; 25) and 54 age-matched women with normal weight.
      
___TAGSTART___BR___TAGEND___Results: The obese women had significantly more tender points and lower dolorimetry thresholds than the normal weight controls.
      
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Objective To study the relationship between soluble tumor necrosis factor receptor (STNFR) 1,2 and insulin resistance (IR). Methods STNFR1 and STNFR2 were measured by ELISA in 43 men and 41 premenopausal women. IR was assessed by Homa Model. Results Obese men and women showed higher levels of STNFR2 than nonobese men and women (P<0.05). No significant difference of STNFR1 level was shown between obese and nonobese. Compared to women, all men showed higher levels of STNFR1 and STNFR2 (P<0.01). Obese men had...

Objective To study the relationship between soluble tumor necrosis factor receptor (STNFR) 1,2 and insulin resistance (IR). Methods STNFR1 and STNFR2 were measured by ELISA in 43 men and 41 premenopausal women. IR was assessed by Homa Model. Results Obese men and women showed higher levels of STNFR2 than nonobese men and women (P<0.05). No significant difference of STNFR1 level was shown between obese and nonobese. Compared to women, all men showed higher levels of STNFR1 and STNFR2 (P<0.01). Obese men had higher levels of STNFR2 than obese women (P<0.05). In all subjects STNFR2 correlated with waist hip ratio (WHR) (r=0.45, P<0.01), fasting plasma insulin (r=0.40, P<0.01), body mass index (BMI) (r=0.34, P<0.05), Homa IR (r=0.32, P<0.05) and fasting insulin (r=0.33, P<0.05). STNFR1 did not associated with any of these variables. In all men STNFR2 positively correlated with leptin (r=0.34, P<0.05),and after adjustment by BMI and WHR, the relationship between them remained significantly (r=0.30, P<0.05). In a multiple stepwise regression analysis, WHR (r=0.29, P<0.01) and STNFR2 (r=0.21, P<0.05) independently influence the value of Homa IR at 41.3%. Conclusion The results show that there is a posistive relationship between STNFR2 and IR, which suggests that the action of TNF system on IR may be through TNFR2.

目的 了解血清可溶性肿瘤坏死因子受体 (STNFR) 1,2与胰岛素抵抗 (IR)的关系。方法 测定 43名男性和 41名绝经期前女性的STNFR1,2。以稳态模型 (HomaModel)公式评估IR。结果 肥胖男、女组STNFR1与非肥胖男、女组相近 ,而其STNFR2高于非肥胖男、女组 ,差异有显著性 (P <0 .0 5 )。所有男性STNFR1和STNFR2水平高于女性 (P <0 .0 1)。所有对象相关分析示STNFR2与臀腰比 (WHR)、空腹血糖、体重指数 (BMI)、HomaIR、空腹胰岛素正相关。STNFR1与上述指标无相关性。在男性中 ,STNFR2与瘦素正相关 (r =0 .34 ,P <0 .0 5 ) ,调整BMI、WHR影响后 ,STNFR2仍与瘦素正相关 (r=0 .30 ,P <0 .0 5 )。逐步回归分析示WHR和STNFR2对HomaIR的影响达 41.3%。结论 STNFR2与IR相关 ,在人类TNF系统对IR的影响可能主要通过TNFR2起作用。

Objective:To study the body fat distribution,cardiovascular disease and diabetes mellitus risk factors in pre and post menopausal obese women.Methods:We selected pre and post menopausal obese women(BMI>27 kg/m 2) whose BMI was matched ( P >0 05) .None of them had hormone replacement therapy.Insulin resistance was evaluated by homeostasis model assessment (HOMA) formula.Intraabdominal fat volume was calculated by the following formula:IAF=0 370×abdominal sagittal diameter -4 85.Results:①In...

Objective:To study the body fat distribution,cardiovascular disease and diabetes mellitus risk factors in pre and post menopausal obese women.Methods:We selected pre and post menopausal obese women(BMI>27 kg/m 2) whose BMI was matched ( P >0 05) .None of them had hormone replacement therapy.Insulin resistance was evaluated by homeostasis model assessment (HOMA) formula.Intraabdominal fat volume was calculated by the following formula:IAF=0 370×abdominal sagittal diameter -4 85.Results:①In age different but BMI Matched post menopausal women,there were not significant differences in insulin and HOMA,but age,WHR and intraabdominal fat ,systolic and diastolic blood pressure,glucose,cholesterol,triglyceride were significantly higher and HDL cholesterol were lower( P <0 05) ;②In age matched pre and post menopausal women there were no significant differences in those mentioned above;③Older post menopausal women(>50 years) had higher systolic blood pressure,WHR,and glucose compared with the younger (<50 year) post menopausal.Conclusion:An increase in abdominal fat accumulation and unfavorable alteration in risk factor disturb post menopausal obese women even if BMI do not change,during menopause transition.Ageing,particular throughout the post menopausal years,has important effects on the detrimental changes associated with menopause.

目的 :观察绝经前后肥胖妇女体脂分布及心血管病、糖尿病的危险因素变化。方法 :筛选肥胖( BMI>2 7kg/m2 )绝经前后妇女 ,其 BMI相似者 ( P>0 .0 5 )并除外接受激素替代治疗个体 ;胰岛素抵抗用HOMA公式计算 ,腹腔内脂肪含量 ( IAF)用公式 [( 0 .370×腹矢状径 ) - 4.85 ]计算。结果 :1 BMI相似而年龄不同绝经后妇女腰臀比、腹腔内脂肪含量、收缩压、血糖、甘油三酯、胆固醇明显升高 ,HDL-胆固醇明显降低 ,胰岛素与 HOMA值无明显变化 ;2年龄与 BMI都相似的个体 ,其上述各项指标无明显变化 ( P>0 .0 5 ) ;3较大年龄绝经妇女比较小年龄绝经妇女有较高的收缩压、腰臀比、血糖。结论 :BMI相似的肥胖妇女其绝经变化、绝经前后年龄差距增大 ,随年龄增大腹腔内脂肪含量增加 ,心血管病的危险因素增加 ,而糖尿病的危险因素并无明显增加

To study the relationship between plasma leptin, adiponectin, insulin, cortisol, aldosterone and BMI in simple obese females, leptin, adiponectin, insulin, cortisol and aldosterone were tested in 48 fat women with BMI ranging 23~24.9kg/m~2 and another 40 with BMI≥25kg/m~2 by radioimmunoassay and immunoradiometric assay. Besides, 42 healthy women(BMI ranging 18~22.9kg/m~2)were also tested as controls. Pearson's correlation and other statistic methods were used in data processing. The results showed that the levels...

To study the relationship between plasma leptin, adiponectin, insulin, cortisol, aldosterone and BMI in simple obese females, leptin, adiponectin, insulin, cortisol and aldosterone were tested in 48 fat women with BMI ranging 23~24.9kg/m~2 and another 40 with BMI≥25kg/m~2 by radioimmunoassay and immunoradiometric assay. Besides, 42 healthy women(BMI ranging 18~22.9kg/m~2)were also tested as controls. Pearson's correlation and other statistic methods were used in data processing. The results showed that the levels of leptin, insulin, cortisol and aldosterone were linearily postively correlated with BMI in obesity groups, and were higher than those in controls remarkably (P<0.01). Meanwhile, the levels of adiponectin were linearily nagatively correlated with BMI in obesity groups. Our conclusion is that along with increase of BMI, the plasma levels of insulin and leptin increase in obese women, whereas the level of adiponectin decreases. The increasing levels of leptin, insulin, cortisol, aldosterone and decreasing level of adiponectin may be partly indicative of the etiology of diabetes, hypertension and nephrosis in obese females.

探讨女性单纯性肥胖患者血液中瘦素(leptin)、脂联素(adiponectin)、胰岛素(insulin)、皮质醇(cortisol)、醛固酮(aldosterone)等水平的变化及与肥胖程度(BMI)的变化关系、相关关系及其对肥胖的调节,为女性单纯性肥胖患者的临床早期干预和有效防治提供理论依据。研究对象分为:女性肥胖前期患者〈BMI范围23~24.9kg/m2〉48例,肥胖者〈BMI≥25kg/m2〉40例,对照组〈BMI范围18~22.9kg/m2〉42例。用放射免疫法(RIA)测定血浆瘦素、脂联素、胰岛素、醛固酮水平,用免疫放射分析法(IRMA)测定血浆皮质醇水平,各变量之间的关系先进行相关分析,然后用直线回归和多元线性回归分析。结果显示,肥胖前期组和肥胖组血清瘦素、胰岛素、皮质醇、醛固酮水平均明显高于对照组(P<0.01),且各变量值之间呈密切相关;血清脂联素水平则明显低于对照组。其中,血清水平变化与BMI呈直线正相关的激素为:瘦素(P=0.0001)、胰岛素(P=0.0034)、皮质醇(P=0.0469)、醛固酮(P=0.0001),均随着BMI升高而升高;与BMI呈直线负相关的激素有脂联素(P=...

探讨女性单纯性肥胖患者血液中瘦素(leptin)、脂联素(adiponectin)、胰岛素(insulin)、皮质醇(cortisol)、醛固酮(aldosterone)等水平的变化及与肥胖程度(BMI)的变化关系、相关关系及其对肥胖的调节,为女性单纯性肥胖患者的临床早期干预和有效防治提供理论依据。研究对象分为:女性肥胖前期患者〈BMI范围23~24.9kg/m2〉48例,肥胖者〈BMI≥25kg/m2〉40例,对照组〈BMI范围18~22.9kg/m2〉42例。用放射免疫法(RIA)测定血浆瘦素、脂联素、胰岛素、醛固酮水平,用免疫放射分析法(IRMA)测定血浆皮质醇水平,各变量之间的关系先进行相关分析,然后用直线回归和多元线性回归分析。结果显示,肥胖前期组和肥胖组血清瘦素、胰岛素、皮质醇、醛固酮水平均明显高于对照组(P<0.01),且各变量值之间呈密切相关;血清脂联素水平则明显低于对照组。其中,血清水平变化与BMI呈直线正相关的激素为:瘦素(P=0.0001)、胰岛素(P=0.0034)、皮质醇(P=0.0469)、醛固酮(P=0.0001),均随着BMI升高而升高;与BMI呈直线负相关的激素有脂联素(P=0.0001),随着BMI升高而降低。在各种激素的相关关系中,瘦素、脂联素的变化与其他激素有明显相关。结论:激素间的互相作用使“瘦素-胰岛素”平衡、“胰岛素-脂联素”调节、“瘦素-胰岛素”调节等反馈环自身适应性调节,当机体体重大量病理性增加后,其机体内分泌体系为减少体内能量的蓄积作出适应性调节,这会改变各种平衡环的相互间动态平衡,为糖尿病、肾病、高血压等病的发生发展提供了条件。

 
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