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   chronic hepatitis b patients 的翻译结果: 查询用时:0.219秒
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chronic hepatitis b patients
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  慢性乙型肝炎患者
     Changes of Peripheral Blood CD4~+、CD8~+、CD3~+ T Lymphocyte Subsets in Chronic Hepatitis B Patients
     慢性乙型肝炎患者外周血CD4~+、CD8~+、CD3~+T淋巴细胞的变化
短句来源
     Th1/Th2 Cytokines in Serum of Chronic Hepatitis B Patients
     慢性乙型肝炎患者血清Th1/Th2型细胞因子水平研究
短句来源
     Study on Th1/Th2 cytokines in serum of chronic hepatitis B patients
     慢性乙型肝炎患者血清Th1/Th2型细胞因子水平研究
短句来源
     Methods 68 chronic hepatitis B patients whose HBVDNA and HBeAg positive are divided into two groups,the LAM+Tα1 treatment group and single LAM group.
     方法将68例HBVDNA与HBeAg阳性的慢性乙型肝炎患者随机分为2组,LAM+Tα1联合治疗组和单一LAM治疗组。
短句来源
     [Conclusions] The YMDD mutation rate was 32.86% in chronic hepatitis B patients treated with Lamivudine for 48~96 weeks. The main mutation type was rtM204V+rtL180M, and the second was rtM 204 I.
     结论慢性乙型肝炎患者应用拉米夫定48 ̄96周YMDD变异率为32.86%,变异类型以rtM204V/rtL180M为主,其次为rtM204I。
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  慢性乙型肝炎
     Changes of Peripheral Blood CD4~+、CD8~+、CD3~+ T Lymphocyte Subsets in Chronic Hepatitis B Patients
     慢性乙型肝炎患者外周血CD4~+、CD8~+、CD3~+T淋巴细胞的变化
短句来源
     Th1/Th2 Cytokines in Serum of Chronic Hepatitis B Patients
     慢性乙型肝炎患者血清Th1/Th2型细胞因子水平研究
短句来源
     Study on Th1/Th2 cytokines in serum of chronic hepatitis B patients
     慢性乙型肝炎患者血清Th1/Th2型细胞因子水平研究
短句来源
     Methods 68 chronic hepatitis B patients whose HBVDNA and HBeAg positive are divided into two groups,the LAM+Tα1 treatment group and single LAM group.
     方法将68例HBVDNA与HBeAg阳性的慢性乙型肝炎患者随机分为2组,LAM+Tα1联合治疗组和单一LAM治疗组。
短句来源
     [Conclusions] The YMDD mutation rate was 32.86% in chronic hepatitis B patients treated with Lamivudine for 48~96 weeks. The main mutation type was rtM204V+rtL180M, and the second was rtM 204 I.
     结论慢性乙型肝炎患者应用拉米夫定48 ̄96周YMDD变异率为32.86%,变异类型以rtM204V/rtL180M为主,其次为rtM204I。
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  慢性乙肝患者
     Association between expression of Th1/Th2 cytokines and HLA-DRB1 07 genes in chronic hepatitis B patients
     HLA-DRB107与慢性乙肝患者Th1/Th2因子表达水平的相关性
短句来源
     The effect of IFN-α1b on the levels of IL-1、sIL-2R and IFN-γ in sera of chronic hepatitis B patients
     IFN-α1b治疗对慢性乙肝患者血清IL-1、sIL-2R和IFN-γ水平的影响
短句来源
     Detection and Signification of C_(3)d and SC_(5b-9) in Plasma of Chronic Hepatitis B Patients
     慢性乙肝患者血浆中C_(3)d和SC_(5b-9)的检测及其意义
短句来源
     CONCLUSION: T cell subsets in the peripheral blood and liver tissues of transgenic mice C57-TgN (adr2.0) SMMU are different from those in human chronic hepatitis B patients.
     结论: C57 TgN(adr2. 0型 )SMMU的HBV转基因小鼠外周血及肝组织中CD的表达与人慢性乙肝患者的外周血及肝组织有明显不同。
短句来源
     Purpose: To discuss the HBVYMDD variants, the HBV DNA disappearing rate and the ALT recovering rate after the treatment of lamivudine in the chronic hepatitis B patients with positive and negative HBeAg.
     目的:探讨HBeAg阳性和阴性慢性乙肝患者经拉米夫定治疗后HBVYMDD变异、HBV DNA消失率、ALT复常率情况。
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  “chronic hepatitis b patients”译为未确定词的双语例句
     Changes of Renin-angiotensin-aldoster one System and Its Clinical Significance in Chronic Hepatitis B Patients
     Changes of Renin-angiotensin-aldoster one System and Its Clinical Significance in Chronic Hepatitis B Patients
短句来源
     The serum cccDNA level of chronic hepatitis B patients was correlated with the level of ALT ( Rs=0.612 p=0.000 < 0.01 ), with AST ( Rs=0.632 p=0.000 < 0.01), with Tbil(Rs=0.337, p=0.008 < 0.01,but Rs<0.4).
     cccDNA值与AST秩相关(Rs=0.632p=0.000<0.01); cccDNA值与Tbil秩相关(Rs=0.337,p=0.008<0.01,但Rs<0.4)。
短句来源
     Haplotypic frequencies of GGCCT (-238/-308/-857/-863/-1031) in chronic hepatitis B patients was significantly lower than that in self-limited infection subjects (P=003), and the frequencies of haplotype GGCAT or GGTAT in chronic hepatitis B patients were clearly higher than those in self-limited infection subjects (P=0.0001; P=0.004).
     TNFA基因-238/-308/-857/-863/-1031组成的单倍型GGCCT的频率在慢性肝炎组显著低于自限性感染组(P=0.03),单倍型GGCAT与GGTAT在慢性肝炎组的频率显著高于自限性感染组(P=0.0001,P=0.004)。
短句来源
     Furthermore, the CD4/CD8 ratio in acute, but not chronic, hepatitis B patients was remarkably higher than that in the healthy individuals (1.19±0.34 vs 1.50±0.54, P<0.05).
     而且,AHB和正常人相比,CD4/CD8的比值有明显的降低(1.19±0.34vs1.50±0.54,P<0.05).
短句来源
     The FF genotype frequency in chronic hepatitis B patients group was 44.6%,higher than 31.7% in asymptomatic HBV carriers group (P<0.05).
     结果单因素分析结果显示FokⅠ位点FF基因型在慢性乙肝组的频率44.6%显著高于无症状HBV携带组的31.7%(P<0.05)。
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  chronic hepatitis b patients
The present study was designed to identify the variations in the core region of the HBV genome in a local population of chronic hepatitis B patients (n = 57) using a PCR-based restriction fragment length polymorphism (PCR-RFLP) method.
      
Identification of hepatitis B virus core mutants by PCR-RFLP in chronic hepatitis B patients from Punjab, Pakistan
      
Biopsy specimens of chronic hepatitis B patients were reevaluated for the presence of hepatic granulomas.
      
We aimed to determine the prevalence of hepatic granulomas in a larger group of chronic hepatitis B patients and to compare their presence with the response to interferon therapy.
      
Our longitudinal studies, although based on a small sample of patients, demonstrate that the population of HBcAg-activated T cells alters during the course of disease in chronic hepatitis B patients.
      
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Among 246 cases of various clinical forms of HBV infection, high titers of antiHBc-IgM could be detected in 77(31.30%). 63.33% of acute, and 36.72% of chronic hepatitis B patients developed high titers of antiHBc-IgM, the differences in positive rates between actue and chronic forms of HBV infection are significant (P <0.05). None of the 65 asymptomatic chronic carriers had a positive result, although their HBsAg titers were high. It is indicated that ELISA technique is highly specific and...

Among 246 cases of various clinical forms of HBV infection, high titers of antiHBc-IgM could be detected in 77(31.30%). 63.33% of acute, and 36.72% of chronic hepatitis B patients developed high titers of antiHBc-IgM, the differences in positive rates between actue and chronic forms of HBV infection are significant (P <0.05). None of the 65 asymptomatic chronic carriers had a positive result, although their HBsAg titers were high. It is indicated that ELISA technique is highly specific and sensitive in the detection of antiHBc-IgM which reflects HBV replication and severity of hepatic damage.

本文用ELISA法检测246例各种 HBV感染,检出较高滴度抗 HBC-IgM 者77人(31.30%)。按检出率高低,急性乙肝(63.33%)高于慢性乙肝(36.72%)(P<0.05),而65例无症状的HBsAg 携带者均呈阴性。因而检查抗HBc-IgM可反映出近期乙肝病毒感染,或提示慢性乙肝较严重的肝损害,此外,尚可避免少数因HBsAg滴度过低而被漏诊的急性期病例。

This study deals with the detection of IFN-γ induced by Con A from peripheral mononuclear cells in 28 cases of chronic hepatitis B patients and 20 normal controls for comparison and the identification of T subsets as defined by monocloned antibodies. The mean titer of IFN-γ induced by Con A in chronic hepatitis B patients was 7.858 ± 1.483 log 2U/ml, the mean titer of normal controls was log 2U/ml, there wad no significant difference between these two groups(P>0.05).however, the Induction of, IFN-γ...

This study deals with the detection of IFN-γ induced by Con A from peripheral mononuclear cells in 28 cases of chronic hepatitis B patients and 20 normal controls for comparison and the identification of T subsets as defined by monocloned antibodies. The mean titer of IFN-γ induced by Con A in chronic hepatitis B patients was 7.858 ± 1.483 log 2U/ml, the mean titer of normal controls was log 2U/ml, there wad no significant difference between these two groups(P>0.05).however, the Induction of, IFN-γ in the patients group showed a wide range of variation among different individuals, with the coefficient of variability (C. V.) of 18.9%, it was greater than that of control group with C.V. of 7.9% only. The T4/T8 ratio of chronic hepatitis B patients was not significantly different with normal controls (p>0.05). But in patients group, the T4/T8 ratio also sh owed a wide range of variation. Among 28 chronic hepatitis B patients, the T4/T8 ratio were abnormal in 14 patients(8 decreased, 6 increased), it was more prominent in HBeA-g positive patients. In 5 patients with decreased production of IFNγ, the T4/T8 ratio was all abnormal(3 decreased, 2 increased). It suggested that in patients which IFN γ production was decreased might have greater derangement in cellular immunity.

本文对28例慢乙肝病人的外周血单个核细胞进行ConA诱生γ干扰素的测定,同时用T细胞单克隆抗体系统检测其T细胞亚群。结果发现,慢乙肝病人ConA诱生的γ干扰素效价为7.858±1.483log2U/ml,而正常对照组为7.839±0.621log2U/ml,两组间无显著性差异,但在慢乙肝病人组内个体间IFN-γ的效价差别显著大于对照组(P<0.05).慢乙肝病人组T细胞亚群的T_4/T_3比例与对照组无显著差异。但IFN-γ反应低下组的5人均有T_4/T_3比例异常。在28例病人中有14例T_4/T_3比例异常(高于或低于正常),且20例HBeAg阳性病人中有12例T_4/T_3比例异常;8例HBeAg阴性病人中仅2例T_4/T_3比例异常。

In this study, we detected HBV marks in the peripheral blood mononuclear cells (PBMCs) and T, B lymphocytes from 38 patients with chronic hepatitis B.HBV marks were found in 29/38 cases (76.3%).Out of 17 patients 4 have positive HBsAg result, 2 positive HBeAg and 14 positive HBV-DNA in PBMCs. Positive HBsAg and HBeAg were found in T cells in 2 out of 21 patients, and HBV-DNA, in 1 patient.Positive HBsAg was observed in B cells in 3 of 21 patients, positive...

In this study, we detected HBV marks in the peripheral blood mononuclear cells (PBMCs) and T, B lymphocytes from 38 patients with chronic hepatitis B.HBV marks were found in 29/38 cases (76.3%).Out of 17 patients 4 have positive HBsAg result, 2 positive HBeAg and 14 positive HBV-DNA in PBMCs. Positive HBsAg and HBeAg were found in T cells in 2 out of 21 patients, and HBV-DNA, in 1 patient.Positive HBsAg was observed in B cells in 3 of 21 patients, positive HBeAg in 6, positive HBV-DNA in 1.The positive ratios of HBV marks of active patients were higher than those of stable ones.These results suggest that HBV may destroy lymphocytes directly, especially during B the active stage of hepatitis,which may be one of the causes for immunological abnormality in chronic hepatitis B patients.

本文报告在慢性乙型肝炎38例的外周血单核细胞(PBMC)和T、B淋巴细胞中检测到HBV标志物阳性29例(76.3%)。其中17例病人的PBMC中HBsAg,HBeAg和HBV-DNA阳性者分别为4,2和14例。21例病人分离出T,B淋巴细胞,其中T细胞中HBsAg,HBeAg与HBV-DNA阳性分别为2,2和1例;B细胞中分别为3,6,1例。血清HBV标志物阳性的病人其PBMC中这些标志物的检出率(13/15例)明显高于血清抗HBc和抗HBe阳性的稳定期病人(3/7例)。提示HBV可能感染和损害慢性乙型肝炎病人的淋巴细胞,这也许是乙型肝炎病人免疫功能异常的原因之一。

 
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