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   genes dna 在 肿瘤学 分类中 的翻译结果: 查询用时:0.38秒
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genes dna
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  基因dna
    Conclusion The regulation of genes including stress response genes,immune related genes,DNA synthesis and repairing genes,metabolic genes may be involved in antitransforming activity of Chlorophylin.
    结论 叶绿酸的抗转化活性与应激反应基因 ,免疫相关基因 ,DNA合成和修复基因 ,代谢相关基因等多类基因的调节有关
短句来源
    Some of the genes were identified by RT PCR. Results Down regulated genes in gastric cancer consist of 60 genes including tumor suppressing genes, apoptosis related genes, DNA replication and transcript or translate related genes, cell cycle related genes, cell migration related genes, etc.
    结果 筛选到 6 0个胃癌下调基因 ,其中包括抑癌基因 ,凋亡相关基因 ,DNA复制、转录、翻译相关基因 ,细胞周期相关基因 ,细胞迁移相关基因等。
短句来源
    Conclusion The regulation of genes including tumor suppressor gene,apoptosis and stress response genes, immune related genes, DNA synthesis and repair genes, metabolism genes may be involved in transforming activity of NiS and BPDE. cDNA microarray technique is effective in screening the differentially expressed genes among different kinds of xenobiotics.
    结论 NiS与BPDE对 16HBE细胞株的转化作用在抑癌基因 ,细胞周期蛋白相关基因 ,细胞凋亡和应激反应基因相关基因 ,DNA合成、修复和重组蛋白相关基因 ,DNA结合、转录和转录因子类基因 ,细胞受体相关基因 ,代谢相关基因 ,蛋白翻译和合成相关基因等多类基因上呈现差异表达。
短句来源
  “genes dna”译为未确定词的双语例句
    Study on polymorphisms in metabolic enzyme genes, DNA repair genes and individual susceptibility to childhood leukemia
    毒物代谢酶、DNA修复基因多态与儿童白血病遗传易感性
短句来源
    Study on polymorphisms in metabolic enzyme genes,DNA repair genes and individual susceptibility to hepatocellular carcinoma
    毒物代谢酶、DNA修复基因多态与肝癌遗传易感性
短句来源
    This is supported by the recent findings that increased DNA methyltransferase levels are connected with the inactivation of some tumor suppressor genes, DNA repair gene, apoptosis regulating gene of cell cycle, hormone receptor gene and inhibition angiopoesis gene. In addition to its potential role in gene expression, the DNA methyltransferase is also implicated in oncogenesis.
    肿瘤细胞中,这些 CpG 岛常变为甲基化状态,其相关基因的表达亦被关闭。 这一观点在对许多基因的研究中也得到了证实,如:肿瘤抑制基因、细胞周期凋亡调节基因、DNA 修复基因、激素受体基因和抑制血管形成基因等。
短句来源
    In recent years, it has been found that resistance to drug after radiation for some tumors (nasopharyngeal carcinoma, lung cancer) emerges, which is the major impediment to successful treatment of many tumor typesAt present, it has been clarified that multidrug resistance of tumor occurs after chemotherapy, which involves many genes such as drug resistance genes, DNA repair gene.
    临床实践发现,某些肿瘤(如肺癌、鼻咽癌、宫颈癌等)在接受放疗后会产生对化疗药物的多药耐药,但迄今为止对这方面的研究报道不多见。 现已明确,肿瘤接受化疗后会出现肿瘤细胞的多药耐药,这种耐药性的产生涉及耐药基因、DNA修复基因等多种基因。
短句来源
    While others like cellular period pro-tein, cytoskeleton and movement protein, receptor genes, DNA demage, repair and recombination, etc.
    而在细胞周期蛋白、细胞骨架和运动、细胞受体、DNA合成和修复及结合和转录等方面则关联甚少。
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  genes dna
Ferritin genes (DNA and RNA) and protein function at the intersection of iron and oxygen chemistry in biology.
      
Screening for mutations in the MODY genes DNA was isolated from peripheral leucocytes.
      
In several regulatory sequences of developmental genes DNA binding sites for regulatory transcription factors are overlapping.
      


AbstractBy Southern blotting hybridization and immunocy-tochernical staining, the structure and expression of p53gene were investigated in 40 patients with myelodysplas-tic syndromes, chronic myelogenous leukemia in blastcrisis or acute leukemias. The results showed that thestructural abnormality of p53 gene was found in 4 pa-tients mainly with ANLL-M5 subtype. High expressionof p53 protein was found in 13 patients and had no rela-tionship with leukemia subtype and the prognosis of thepatients.Key...

AbstractBy Southern blotting hybridization and immunocy-tochernical staining, the structure and expression of p53gene were investigated in 40 patients with myelodysplas-tic syndromes, chronic myelogenous leukemia in blastcrisis or acute leukemias. The results showed that thestructural abnormality of p53 gene was found in 4 pa-tients mainly with ANLL-M5 subtype. High expressionof p53 protein was found in 13 patients and had no rela-tionship with leukemia subtype and the prognosis of thepatients.Key wards Leukemia p53 gene DNA blot-ting hybridization Immunoenzymetechnique

对40例不同类型的白血病和骨髓增生异常综合征(MDS)患者进行p53基因的DNA印迹杂交分析和p53蛋白的免疫组化染色,发现4例有p53基因结构异常,主要聚集在AML-M5亚型;13例有p53蛋白高表达,与白血病类型,患者预后无直接关系。

P53 gene DNA of 7 cases of 8 hepatocellular carcinomas(HCC) with positive P53 mutation (Guangxi Sciences, 1995, 2 (1): 55~57) were detected by and proceeded for PCR-SSCP analysis and DNA direct sequencing. 7 HCCs showed a single point abnormality at position 3 of exon 7codon 249. One showed a microdelection at position 3 of codon 249 leading to a frame shift, othersix showed two bands for mutants T & C at the third base of codon 249, leading to a polymorphic mutation form. No other mutation was in...

P53 gene DNA of 7 cases of 8 hepatocellular carcinomas(HCC) with positive P53 mutation (Guangxi Sciences, 1995, 2 (1): 55~57) were detected by and proceeded for PCR-SSCP analysis and DNA direct sequencing. 7 HCCs showed a single point abnormality at position 3 of exon 7codon 249. One showed a microdelection at position 3 of codon 249 leading to a frame shift, othersix showed two bands for mutants T & C at the third base of codon 249, leading to a polymorphic mutation form. No other mutation was in exon 5, 6, 8 and 9. There may be more other factors besides aftaloxin B1 for these polymorphic mutations. Nanning prefecture could be confirmed as a third area in the world with mutational hot-spot at canon 249 in the P53 gene in HCC.

对P53阳性的8例肝细胞性肝癌(HCC)广西科学,1995,2(1):55~57)中的7例的P53基因进行DNA单键构象多态性分析(SSCP)和PCR扩增物直接测序。结果,7例均在P53第7外显子第249编码区的3号位发现异常。1例在249编码区的第3碱基微小丧失引起乱码突变;另6例在此位点同时出现突变的T和C带,成为的多态性突变形式。外显子5、6、8和9没有异常。估计除黄曲霉毒素B1外可能有别的致癌因素协同作用造成此种多态性。认为南宁地区是继中国江苏启东和莫桑比克后的第3个HCCP53基因249编码区有集中突变热点的地区。

To investigate the role of asbestos fibers in the etiology of human malignant mesothelioma,the point mutation in p53 gene DNA sample of 12 patients from crocidolite contamination area was examined.Non isotopic PCR SSCP was used to detect point mutation of p53 exons 5,6,7,8 of p53 gene in paraffin embedded mesothelioma tissues.After 4 DNA fragments of p53 exons 5 ̄8 in p53 gene were put to undergo electrophoresis in a nondenaturing polyacrylamide gel,the abnormal migration of the single...

To investigate the role of asbestos fibers in the etiology of human malignant mesothelioma,the point mutation in p53 gene DNA sample of 12 patients from crocidolite contamination area was examined.Non isotopic PCR SSCP was used to detect point mutation of p53 exons 5,6,7,8 of p53 gene in paraffin embedded mesothelioma tissues.After 4 DNA fragments of p53 exons 5 ̄8 in p53 gene were put to undergo electrophoresis in a nondenaturing polyacrylamide gel,the abnormal migration of the single stranded DNA was identified in 4 out of 12 cases.The mutations of 2 cases were found in exon 5,2 cases in exon 6.The result suggested that point mutation of p53 gene may be present in human malignant mesothelioma.

为研究石棉纤维在人恶性间皮瘤病因学中的作用,检查了青石棉污染区12例间皮瘤DNA样品的p53基因点突变。应用非同位素PCR-SSCP方法,聚丙烯酰胺凝胶电泳分析了p53基因5,6,7,8外显子的4个DNA片段,结果显示:4例有异常移动的单链DNA电泳带,其中2例位于外显子5,2例位于外显子6。提示:这些病例的p53基因存在点突变

 
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