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osteocalcin
相关语句
  骨钙素
    Study of serum osteocalcin and bone mineral density measurement in patients with osteal disorders
    骨骼病变患者血清中骨钙素与骨矿含量的研究
短句来源
    Changes of serum osteocalcin and bone loss in ovariectomized rats
    卵巢切除大鼠血清三种骨钙素变化与骨丢失
短句来源
    The Association between Vitamin D Receptor Gene Polymorphisms,Bone Mineral Density and Osteocalcin in Chinese Women
    中国妇女维生素D受体基因型与骨密度及骨钙素关系的研究
短句来源
    RESULTS: ① Characterization of hOB in vitro: The ALP levels in normal human osteoblasts were (74.3±4.7) U/g protein, and the detectable osteocalcin levels was (3.84±0.39) μg/L protein], which suggested that osteoblasts were the primary cell type found in our bone-derived cell cultures from donors.
    结果: ①人成骨细胞鉴定: 人成骨细胞分泌的碱性磷酸酶活性为(74.3±4.7) U/g; 培养上清液中骨钙素浓度为(3.84±0.39) μg/L。
短句来源
    Immunocytochemical detection showed positive CTLA-4Ig expression in CTLA-4Ig-hMSCs and strongly positive alkali phosphatase staining,as well as positive expression of osteocalcin. Macrocyclin fluorescent labeling indicated there were calcium deposits among hMSCs.
    免疫细胞化学结果显示,CTLA-4Ig-hMSCs的CTLA-4Ig蛋白表达阳性,诱导培养3周的CTLA-4Ig-hMSCs,碱性磷酸酶染色呈强阳性,免疫细胞化学检测骨钙素表达阳性,钙的四环素荧光标记法显示细胞间有钙的沉积。
短句来源
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  “osteocalcin”译为未确定词的双语例句
    Determination of Serum Osteocalcin in Middle and Elderly Aged Healthy Subjects
    Determination of Serum Osteocalcin inMiddle and Elderly Aged Healthy Subjects
短句来源
    The ways of immunocytochemistry, RT-PCR were used to analyse the gene expression of OSX(Osterx),osteocalcin (OCN) ,and the protein of alkaline phosphatase (ALP)、 type I collagen (COL1) and OCN;
    分析与成骨细胞分化有关的OSX(Osterx)、骨钙蛋白(Osteocalcin OCN)基因、碱性磷酸酶(alkaline phosphatase,ALP)、Ⅰ型胶原(type Ⅰ collagen,COLl)、OCN蛋白的表达;
短句来源
    The results were as following: after LMP-1 mRNA was blocked by LMP-1 antisense, both the activity of ALP and synthesis of osteocalcin were reduced. The expression of collagen type Ⅰprotein and mRNA was down-regulated.
    结果显示 :LMP 1mRNA被LMP 1antisense阻断后 ,ALP活性降低、OC分泌减少、Ⅰ型胶原蛋白和mRNA的表达下降。
短句来源
    The expressions of alkaline phosphatase(AKP),osteocalcin and bone tubercula were all examined. Results:It was reasonable that hMSCs were plated at 1×10 5~3×10 5/cm 2cell density and the medium was changed after 48 hours.
    结果 :hMSCs原代培养种植细胞密度为 1× 10 5~ 3× 10 5/cm2 ,4 8h后换液的方法较合理。
短句来源
    ② At day 5 after transfection,from the results of immunohistochemistry,the staining of rhBMP 2,ALP,type collagen Ⅰ and expression of osteocalcin were found positive in AdrhBMP 2 mediated group,and weakly positive in AdGFP transfected and untreansfected groups.
    ②转染后第5天,免疫组化染色显示AdrhBMP-2转染细胞组rhBMP-2阳性、ALP阳性、Ⅰ型胶原阳性,细胞转染AdGFP组和未转染细胞组上述指标染色呈弱阳性。
短句来源
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  osteocalcin
The content of osteocalcin was increased after space flights.
      
The cell morphology and viability, alkaline phosphatase and osteocalcin, as markers of osteoblast proliferation were evaluated at 3, 7 and 25 days of culture.
      
Cells cultured into the COL/β-TCP scaffold presented osteoblast phenotype, intense staining of alkaline phosphatase and increased production of osteocalcin.
      
Furthermore, the mRNA expression of type I collagen, osteocalcin and osteonectin was semi-quantitively evaluated by real-time reverse transcriptase-polymerase chain reaction (RT-PCR).
      
The osteogenic differentiation of PCs was further demonstrated by the detection of type I collagen, osteocalcin and osteonectin gene expression.
      
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The effect of epidermal growth factor(ECF) on bone resorption was determined in neonatal mouse calvaria in organ culture. The results showed that EGF at concentration of 1, 10, 100 ng/ ml stimulated the release of calcium into the supernatant(P<0.001). In addition, ECF at concentration of 1 ng / ml increased the release of osteocalcin into the medium during 3 days of culture(p<0.02). Active resorption was found in cultured calvaria treated with ECF as shown by histological examination.Thus, we concluded...

The effect of epidermal growth factor(ECF) on bone resorption was determined in neonatal mouse calvaria in organ culture. The results showed that EGF at concentration of 1, 10, 100 ng/ ml stimulated the release of calcium into the supernatant(P<0.001). In addition, ECF at concentration of 1 ng / ml increased the release of osteocalcin into the medium during 3 days of culture(p<0.02). Active resorption was found in cultured calvaria treated with ECF as shown by histological examination.Thus, we concluded that ECF stimulates bone resorption in neonatal mouse calvaria in organ culture.

采用新生小鼠颅骨体外培养模型,研究了表皮生长因子调节骨吸收的作用,发现1、10、100ng/ml的表皮生长因子能增加培养上清液中钙的含量,差异非常显著(P<0.001).此外发现:表皮生长因子(1ng/ml)能刺激培养颅骨释放骨钙素。组织学观察发现:表皮生长因子处理过的颅骨骨吸收活跃。结果提示,表皮生长因子具有强烈刺激骨吸收的作用。

Fasting urine and blood samples were collected from 1928 healthy subjects aged 0~87 years and 5345 patients in Beijing and the biochemical markers were measured. The results indicated that serum 25 hydroxy vitamin D(25OHD), alkaline phosphatase(ALP), osteocalcin(BGP), parathyroid hormone(PTH) urine type I collegen crosslinked N-telopeptides creatinine ratio(NTX/Cr) and hydroxyproline creatinine ratio (HOP/Cr) were significant correlates with age. Serum 25OHD, BGP,urine NTX/Cr and HOP/Cr could be used to...

Fasting urine and blood samples were collected from 1928 healthy subjects aged 0~87 years and 5345 patients in Beijing and the biochemical markers were measured. The results indicated that serum 25 hydroxy vitamin D(25OHD), alkaline phosphatase(ALP), osteocalcin(BGP), parathyroid hormone(PTH) urine type I collegen crosslinked N-telopeptides creatinine ratio(NTX/Cr) and hydroxyproline creatinine ratio (HOP/Cr) were significant correlates with age. Serum 25OHD, BGP,urine NTX/Cr and HOP/Cr could be used to predict bone mass. 1, 25 ((OH)2D3, 25OHD,NTX/Cr, HOP/Cr are able to discriminate between premenopansal and late osteoprotic patients. Agerelated bone loss may be due to a fall in 1,25(OH)2D3 and a rise in PTH and renal dysfunction. Postmenopausal bone loss could be due to estrogen deficiency.

本文收集了北京地区1928名不同年龄(0~87岁)健康人及5345例20余种疾病患者空腹尿及血,并对其骨代谢生化指标进行测定。结果表明:血清25羟基维生素D(25OHD),碱性磷酸酶(ALP),骨钙素(BGP),甲状旁腺激素(PTH),尿Ⅰ型胶原交联N末端肽与肌酐比值(NTX/Cr)及羟脯氨酸与肌酐比值(HOP/Cr)与年龄显著相关。血清25OHD,BGP,尿NTX/Cr及HOP/Cr可用于预测骨量。1,25(ON)2D3,25OHD,NTX/Cr和NOP/Cr可用于区分绝经前与绝经后骨质疏松妇女。与年龄有关的骨丢失可能与1,25(OH)2D3的降低、PTH的升高及肾功能减退有关;绝经后骨丢失与雌激素缺乏有关。

Serum osteocalcin in 46 patients with osteal disorders was tested using radioimmunoassay (RIA).In some of cases, their forearm bone mineral density and serum AKP,calcimn and phosphorus were determined,and compared with osteocalcin.As a result,the osteocalcin level was higher than the normal controls in serum of 32 patients with primary osteoporosis(P<0.01),7 patients with primary hyperparathyroidism(P<0.01)and 2 patients with chronic renal insufficiency(P<0.05).Therefore serum osteocalcin...

Serum osteocalcin in 46 patients with osteal disorders was tested using radioimmunoassay (RIA).In some of cases, their forearm bone mineral density and serum AKP,calcimn and phosphorus were determined,and compared with osteocalcin.As a result,the osteocalcin level was higher than the normal controls in serum of 32 patients with primary osteoporosis(P<0.01),7 patients with primary hyperparathyroidism(P<0.01)and 2 patients with chronic renal insufficiency(P<0.05).Therefore serum osteocalcin and bone mineral density deterfornation have some value for the diagnosis of osteoporotic diseases.

用放射免疫分析法测定了46例骨骼疾病患者血清骨钙素含量,并与其中部分病例的骨矿含量、血清碱性磷酸酶、钙、磷等指标进行了比较,结果提示32例原发性骨质疏松症患者和7例原发性甲状旁腺机能亢进患者血清BGP均明显高于对照组(P<0.01),2例慢性肾衰患者的BGP也高于正常组(P<0.05);骨矿含量测定对诊断骨质疏松症等骨病有一定的参考价值。

 
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