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osteocalcin
相关语句
  骨钙素
    Osteocalcin and children's growth and development
    骨钙素与儿童生长发育
短句来源
    Determination and analysis of serum osteocalcin and calcitonin in cord blood of new born infants in excess-fluoride-area
    高氟地区新生儿脐血血清骨钙素与降钙素测定及分析
短句来源
    Study of changes on serum osteocalcin and 25-dihydroxyvitamine D3 and calcium,phosphorus and magnesium in cord blood of the newborns with intrauterine growth retardation
    宫内生长迟缓新生儿的骨钙素、25-OHD_3及钙磷镁代谢的研究
短句来源
    A Study of Changes of Serum Osteocalcin and 25-dihydroxyvitamine D_3 and Calcium, Phosphorus and Magnesium in Cord Blood of the Newborns with Intrauterine Growth Retardation
    宫内生长迟缓新生儿脐血骨钙素、25-OHD_3及钙磷变化的研究
短句来源
    Results\ After exercise treatment,both growth rate and the ratio of height and bone age increased significantly on condition of no sexual inhibition,both serum osteocalcin and IGF-1 level increased while serum IGFBP-3 level and IGFBP-3/IGF-1 decreased significantly.
    结果 ICPP女孩单纯运动治疗后在性腺不抑制的情况下生长速度显著加快 ,身高年龄与骨龄的比值显著增加 ,空腹血清骨钙素、胰岛素样生长因子 1(IGF - 1)水平显著增加 ,胰岛素样生长因子结合蛋白 3(IGFBP - 3)水平及IGFBP - 3/IGF - 1比值显著降低。
短句来源
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  “osteocalcin”译为未确定词的双语例句
    Objective: The concentrations of the serum insulin-like growth factor-I(IGF-1),bone specific alkaline phosphatase (BAP) and osteocalcin (OC) are measured in children of idiopathic short stature(ISS) and try to explore the relationship between these indexs and growth of children.
    目的:检测特发性身材矮小(ISS)患儿血清中胰岛素样生长因子-1(IGF-1)、骨碱性磷酸酶(bone specific alkaline phosphatase,BAP)、骨钙蛋白(osteocalcin,OC)水平,探讨三指标之间的相关性及其与生长发育的关系。
短句来源
    Methods Forty-eight children with idiopathic nephrotic syndrome(INS) were assigned as study group treated with GC and caltrate. Serum levels of osteocalcin(BGP),bone-specific alkaline phosphatase(BALP),parathyroid hormone(PTH) and calcium(Ca) were measured before GC treatment(active stage),just after the urine protein turned to negative(paracme) and after 5 months of the relief from nephropathy state(convalescence stage).
    方法选择初发特发性肾病综合征(INS)患儿48例,予以GC治疗,并辅以钙尔奇D片,分别在GC治疗前(活动期)、激素治疗尿蛋白转阴后(缓解期)及肾病持续缓解5个月时(恢复期)检测血清骨钙蛋白(BGP)、骨特异性碱性磷酸酶(BALP)、甲状旁腺素(PTH)和钙水平。
短句来源
    Effects of prednison on serum osteocalcin and alkaline phosphatase in children with nephrotic syndrome
    泼尼松治疗对肾病综合征患儿血清骨钙蛋白和碱性磷酸酶的影响
短句来源
    Correlation analysis of serum osteocalcin and pain in knees in ad olescents and children at night
    少儿膝关节夜间痛的相关性研究
短句来源
    The third Objectives of it is to investigate the relation between bone alkalinephosphatase and osteocalcin. Methods: 13 cases with middle or little simple bone cyst in which have 10 males and 3 females between 4 years 3 months and 11 years 10 months old (mean age was 8 years 11 months old) were treated by surgery.
    方法:对中、小型骨囊肿共13例(其中男10例,女3例,年龄4y3m至11y10m,平均8y11m,肱骨5例,股骨7例,胫骨1例。)
短句来源
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  osteocalcin
The content of osteocalcin was increased after space flights.
      
The cell morphology and viability, alkaline phosphatase and osteocalcin, as markers of osteoblast proliferation were evaluated at 3, 7 and 25 days of culture.
      
Cells cultured into the COL/β-TCP scaffold presented osteoblast phenotype, intense staining of alkaline phosphatase and increased production of osteocalcin.
      
Furthermore, the mRNA expression of type I collagen, osteocalcin and osteonectin was semi-quantitively evaluated by real-time reverse transcriptase-polymerase chain reaction (RT-PCR).
      
The osteogenic differentiation of PCs was further demonstrated by the detection of type I collagen, osteocalcin and osteonectin gene expression.
      
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Osteocalcin is secreted by osteobiasts and is specific to bone,which is the marker of the formation of bone. This study presented the serum osteocalcin levels in the growing rats fed by low-calcium diet and normal vitamin D intake to demonstrate the osteoblast activeted during low-calcium intake.

本文研究低钙摄入、维生素D供给正常时幼鼠血中骨钙素水平,以了解低钙时成骨细胞活性。实验采用60只21~23日Wistar断乳幼鼠,随机分为四组:A组,正常钙与VitD摄X组;B组,中度低钙组;C组,重度低钙组;D组,VitD缺乏组。定期监测血25-(OH)D_3水平。于实验中期(3周),末期(6周)分别处死1/2幼鼠,取血与左股骨标本。测血骨钙素水平,以股骨钙与股骨长计算股骨含钙指数。实验建立低钙与低VitD动物模型。结果发现严重低钙幼鼠股骨生长显著落后,VitD缺乏幼鼠股骨生长与正常组相似。低钙与VitD缺乏幼鼠股骨含钙指数均明显低于正常组,低钙组更严重。低钙组幼鼠血骨钙素水平略高于正常组,VitD缺乏幼鼠血骨钙素有增高趋势;提示低钙时股骨增生的成骨细胞活性低下,VitD缺乏幼鼠骨生长受阻程度不如低钙组明显,推测VitD缺乏与低钙时对成骨细胞的作用机理不同。本文研究证实低钙对生长期骨骼的影响远远超过临床估计。

Objective To explore the distribution frequencies of vitamin D receptor(VDR) gene polymorphisms in Chinese and the relationship between VDR genotypes and bone mineral density (BMD) or serum osteocalcin level in Chinese women. Methods Polymorphisms of VDR gene were analyzed by polymerase chain reaction (PCR) to amplify the DNA sequence and three restriction enzymes (namely BsmI, ApaI and TaqI) to digest the PCR products in 223 subjects. Some of the VDR genotypes were also confirmed by Southern hybridization...

Objective To explore the distribution frequencies of vitamin D receptor(VDR) gene polymorphisms in Chinese and the relationship between VDR genotypes and bone mineral density (BMD) or serum osteocalcin level in Chinese women. Methods Polymorphisms of VDR gene were analyzed by polymerase chain reaction (PCR) to amplify the DNA sequence and three restriction enzymes (namely BsmI, ApaI and TaqI) to digest the PCR products in 223 subjects. Some of the VDR genotypes were also confirmed by Southern hybridization analysis. BMD was measured at the spine and proximal femur by dual energy X ray absorptiometry (DEXA). Serum osteocalcin concentrations were determined by radioimmunoassay. Results Chinese had high frequencies of "b,a,T" alleles, 95%, 75% and 95% respectively, which were much different from Caucasians. "BB" or "AA" genotype had tendency for higher BMD at some sites in the group of young women, whereas in the group of postmenopausal women, "bb" or "aa" genotype had relationship with lower BMD at femoral neck and trochanter. Furthermore, no relationship were found between VDR genotypes and the serum osteocalcin level in Chinese women. Conclusions Allele frenquencies of VDR gene in Chinese are different from those in Caucasians.VDR gene polymorphisms are associated with BMD in Chinese, but in a different pattern from other reports. Further study on predicting function of VDR for osteoporosis is necessary.

PolymorphismsofvitaminDreceptorgeneanditsasociationwithbonemineraldensityandosteocalcininChineseZhaoJinxiu赵金秀,ZhouXueying周学瀛,...

Objective To study the effect of short-term inhalation of glucocorticoids on bone turnover markers. Methods 8 asthmatic children,with no history of using glucocorticoids,continuously inhaled BDP 200~300μg/d for 1~2 months.Before and after the experiment,serum Ca,P,AKP,osteocalcin,urine hydroxy proline/creatinine ratio were tested.Results After BDP inhalation,serum osteocalcin level decreased 20 56%( P <0 05).Serum Ca,P,AKP levels were of no significant changes,as well as urine hydroxyproline/creatinine.Conclusion...

Objective To study the effect of short-term inhalation of glucocorticoids on bone turnover markers. Methods 8 asthmatic children,with no history of using glucocorticoids,continuously inhaled BDP 200~300μg/d for 1~2 months.Before and after the experiment,serum Ca,P,AKP,osteocalcin,urine hydroxy proline/creatinine ratio were tested.Results After BDP inhalation,serum osteocalcin level decreased 20 56%( P <0 05).Serum Ca,P,AKP levels were of no significant changes,as well as urine hydroxyproline/creatinine.Conclusion Short-term inhalation of low dose BDP may induce the occurrence of inhibition of bone formation,Long-term and dynamic observation of serum osteocalcin is necessary.

目的研究短期吸入小剂量糖皮质激素对哮喘儿童骨转换指标的影响。方法对8例无激素治疗史哮喘儿童持续吸入二丙酸倍氯米松(BDP)200~300μg/d,疗程1~2个月。疗程开始与结束时分别检测血清钙、磷、碱性磷酸酶、骨钙素及尿羟脯氨酸/肌酐比值。结果吸入BDP1~2个月后患儿血清骨钙素水平下降了2056%,P<005,而血钙、磷、碱性磷酸酶水平和尿羟脯氨酸/肌酐比值无明显改变。结论短期内吸入BDP200~300μg/d有可能发生骨生成抑制。有必要对血清骨钙素水平进行长期动态观察

 
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