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   botulinum toxin type a (bta) 的翻译结果: 查询用时:0.01秒
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botulinum toxin type a bta
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     Application of botulinum toxin type A for strabismus
     肉毒杆菌毒素A在斜视中的应用
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     Treatment of dystonia with Botulinum toxin type A
     A型肉毒毒素治疗肌张力障碍
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     Treatment of blepharospasm with type A botulinum toxin
     应用A型肉毒素治疗眼睑痉挛
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     Botulinum toxin type A in treating muscle hypertonia
     A型肉毒毒素治疗肌张力过强
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  botulinum toxin type a bta
Sixty patients with idiopathic cervical dystonia were treated a total of 240 times with botulinum toxin type A (BTA).
      


AIM: To evaluate the efficacy and safety of botulinum toxin type A (BTA) in treating hemifacial spasm and cranial_cervical dystonia. METHODS: Injection sites and dosage of BTA were depending on the involved muscles. The efficacy and side effects were compared between the results before and after injection. RESULTS: The 250 patients with hemifacial spasm received a total 1028 injection sessions. Seventy_eight patients with blephrospasm received 260 sessions. Fifty_three patients...

AIM: To evaluate the efficacy and safety of botulinum toxin type A (BTA) in treating hemifacial spasm and cranial_cervical dystonia. METHODS: Injection sites and dosage of BTA were depending on the involved muscles. The efficacy and side effects were compared between the results before and after injection. RESULTS: The 250 patients with hemifacial spasm received a total 1028 injection sessions. Seventy_eight patients with blephrospasm received 260 sessions. Fifty_three patients with oramandibular spasm received 181 sessions. Twenty_eight patients with spasmodic torticollis received 79 sessions. The effective rates and average relief duration were 100% and 16 wk±s 4 wk, 93.9% and 15 wk±4 wk, 85.1% and 14 wk±4 wk, 81% and 14 wk±4 wk, respectively. Side effects were mild and reversible. CONCLUSION: Local injection of BTA is a simple, effective and safe therapy for hemifacial spasm and cranial_cervical dystonia.

目的:探讨A型肉毒毒素局部注射治疗面肌痉挛、各型头颈肌张力障碍的临床疗效和安全性。方法:采用A型肉毒毒素局部多点注射痉挛肌肉,治疗前后对照。结果:治疗面肌痉挛250例(1028轮次),有效率100%,作用持续16wk±s4wk;睑痉挛78例(260轮次),有效率93.9%,作用持续15wk±4wk;口颌肌痉挛53例(181轮次),有效率85.1%,作用持续14wk±4wk;痉挛性斜颈28例(79轮次),有效率81%,作用持续14wk±4wk。副作用轻微、可逆。结论:该疗法安全、有效,可作为面肌痉挛及各型头颈部肌张力障碍的首选治疗。

AIM: To evaluate the efficacy and safety of small dosage(2.0 U) of botulinum toxin type A(BTA) in treating hemifacial spasm. METHODS: Fifty-eight patients(M 24,F 34; age 47 a±s 13 a) with hemifacial spasm were injected with BTA 2.0 U on the spasmodic muscles. The efficacy and side effects were compared between the results before and after injection. RESULTS: Fifty-eight patients with hemifacial spasm received injection. The effective rates and average relief duration were 97...

AIM: To evaluate the efficacy and safety of small dosage(2.0 U) of botulinum toxin type A(BTA) in treating hemifacial spasm. METHODS: Fifty-eight patients(M 24,F 34; age 47 a±s 13 a) with hemifacial spasm were injected with BTA 2.0 U on the spasmodic muscles. The efficacy and side effects were compared between the results before and after injection. RESULTS: Fifty-eight patients with hemifacial spasm received injection. The effective rates and average relief duration were 97 %(56/58) and 15 wk±4 wk. Side effects were mild and reversible. CONCLUSION: Local injection of small dosage of BTA in treating hemifacial spasm is effective and side effects are less.

目的 :探讨小剂量 (2 .0U )A型肉毒毒素局部注射治疗面肌痉挛的临床疗效和安全性。方法 :面肌痉挛病人 5 8例 (男性 2 4例 ,女性 34例 ;年龄 4 7a±s 13a)采用A型肉毒毒素 (2 .0U )局部多点注射痉挛肌肉 ,治疗前后对照。结果 :治疗面肌痉挛 5 8例 ,有效率 97% (5 6 /5 8) ,作用持续 15wk± 4wk。副作用轻微、可逆。结论 :小剂量A型肉毒毒素治疗面肌痉挛疗效肯定 ,副作用少

Objective:To investigate the effect and mechanisms of botulinum toxin type A(BTA)on vasomotor rhinitis.Method:A retrospective study of 32 patients with vasomotor rhinitis who received BTA injection at 4 points in bilateral nasal cavities with 2.5 units at each point had been done.The state of rhinorrhea, nasal obstruction, sneeze and nasal mucosa edema of each patient were recorded and scored before and after the application of BTA respectively with follow-ups of 6~30 months....

Objective:To investigate the effect and mechanisms of botulinum toxin type A(BTA)on vasomotor rhinitis.Method:A retrospective study of 32 patients with vasomotor rhinitis who received BTA injection at 4 points in bilateral nasal cavities with 2.5 units at each point had been done.The state of rhinorrhea, nasal obstruction, sneeze and nasal mucosa edema of each patient were recorded and scored before and after the application of BTA respectively with follow-ups of 6~30 months. Twelve guinea pigs were randomly divided into 2 groups: BTA group and control group. Merocel sponge soaked with 10 units ( 0.2 ml) BTA was put into left nasal cavity under general anesthesia for one hour in BTA group. Saline replaced BTA in control group. The inferior turbinate mucosa of guinea pig ware harvested under general anesthesia at 7, 14, 28 days after BTA treatment and was observed with HE staining and electron microscope.Result:Rhinorrhea improved significantly in all 32 patients while sneeze, nasal obstruction and mucosa edema reduced partly. The reducing of rhinorrhea lasted averagely 6 weeks. Twelve patients had an episode of nasal dryness or increased rhinorrhea at the day of injection. No other complications were found. Seven, fourteen days after local BTA application, the degenerations of glandular epithelium and canal epithelium were observed in nasal mucosa of guinea pigs. Most of the glandular cells showed normal at 28 days after BTA treatment.Conclusion:BTA can induce the degeneration of glandular cells in nasal mucosa and thus obviously relieve over rhinorrhea of patients with vasomotor rhinitis.

目的 :探讨A型肉毒杆菌毒素 (BTA)治疗血管运动性鼻炎的作用及机制。方法 :32例血管运动性鼻炎患者鼻腔注射BTA ,每侧鼻腔各注射两点 ,每点 2 .5U ,总量 10U。记录注射前后鼻溢液、鼻塞、喷嚏、鼻黏膜水肿的情况并评分。 12只豚鼠随机分为BTA组和对照组。BTA组左侧鼻腔以浸有 10U(0 .2ml)BTA的Mero cel海绵作用 1h ;对照组以生理盐水代替BTA。分别于用药后第 7、14、2 8天全麻下切取豚鼠左侧下鼻甲黏膜 ,行苏木精 伊红染色及电镜观察。结果 :鼻溢液亢进完全缓解 2 6例 (81.3% ) ,明显缓解 6例 (18.8% ) ;打喷嚏完全缓解 10例 (31.3% ) ,部分缓解 4例 (12 .5 % ) ,无缓解 18例 (5 6 .3% ) ;鼻塞完全缓解 4例 (14 .8% ) ,部分缓解 5例(18.5 % ) ,无缓解 18例 (6 6 .7% ) ;鼻黏膜肿胀完全缓解 8例 (2 5 .0 % ) ,明显缓解 6例 (18.8% ) ,部分缓解 4例(12 .5 % ) ,无缓解 14例 (4 3.8% )。 12例患者有一过性鼻干或注射当天鼻溢液加...

目的 :探讨A型肉毒杆菌毒素 (BTA)治疗血管运动性鼻炎的作用及机制。方法 :32例血管运动性鼻炎患者鼻腔注射BTA ,每侧鼻腔各注射两点 ,每点 2 .5U ,总量 10U。记录注射前后鼻溢液、鼻塞、喷嚏、鼻黏膜水肿的情况并评分。 12只豚鼠随机分为BTA组和对照组。BTA组左侧鼻腔以浸有 10U(0 .2ml)BTA的Mero cel海绵作用 1h ;对照组以生理盐水代替BTA。分别于用药后第 7、14、2 8天全麻下切取豚鼠左侧下鼻甲黏膜 ,行苏木精 伊红染色及电镜观察。结果 :鼻溢液亢进完全缓解 2 6例 (81.3% ) ,明显缓解 6例 (18.8% ) ;打喷嚏完全缓解 10例 (31.3% ) ,部分缓解 4例 (12 .5 % ) ,无缓解 18例 (5 6 .3% ) ;鼻塞完全缓解 4例 (14 .8% ) ,部分缓解 5例(18.5 % ) ,无缓解 18例 (6 6 .7% ) ;鼻黏膜肿胀完全缓解 8例 (2 5 .0 % ) ,明显缓解 6例 (18.8% ) ,部分缓解 4例(12 .5 % ) ,无缓解 14例 (4 3.8% )。 12例患者有一过性鼻干或注射当天鼻溢液加重 ,无其他并发症。BTA局部应用 7、14d ,豚鼠鼻黏膜下腺上皮及导管上皮退化、变性 ,部分腺细胞呈不可逆变性 ;2 8d后大部分腺细胞恢复正常。结论 :BTA可引起鼻黏膜腺细胞变性 ,明显减轻血管运动性鼻炎鼻溢液亢进的症状

 
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