RESULTS: The positive expression rates of p gp, GST π and TopoⅡ were 45.7%, 71.3%and 34.0% respectively in osteosarcoma, but they were 0, 12.5% and 87.5% in ossifying fibroma and 20%, 33.3% and 93.3% in normal bone tissues.
Result:Survivin positive expression rate was 63.17% in osteosarcoma,VEGF positive expression rate was 55.26% in osteosarcoma,but no expression of survivin and VEGF was detected in normal osseous tissue.
Results The mean follow-up time was 6.2 months (3 to 9 months). Osteoset pellets began to be absorbed after 1 to 3 months of operation, and were totally absorbed and replaced by osseous tissue after 4 to 6 months.
Biomimetic strengthening polylactide scaffold materials for bone tissue engineering
The novel composite mainly consists of nano-hydroxyapatite (n-HA), which is the main inorganic content in natural bone tissue for the PLA.
The crystal degree of the n-HA in the composite is low and the crystal size is very small, which is similar to that of natural bone.
The biomimetic three-dimensional porous composite can serve as a kind of excellent scaffold material for bone tissue engineering because of its microstructure and properties.
The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
In summary, the SIS/PLGA scaffolds have osteoconductive effects to allow remodeling and replacement by osseous tissue.
Interestingly, we also found the other two types of mutations within the Gsα gene in the patient's affected osseous tissue.
Two patients are described whose skeletal muscle hemangiomas contained abundant osseous tissue.
It is concluded that the histopathologic finding of excessive retentions of chondro-osseous tissue and failure of remodeling of bones is the result of retarded osteocytic osteolysis and osteocytic chondrolysis.
Histopathology of chondro-osseous tissue confirms the similarity in pathologic findings to Kniest dysplasia.