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periodontal fibroblasts
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  牙周膜成纤维细胞
     Conclusion: It was concluded that estrogen could accelerate periodontal fibroblasts'migration and differentiation .
     结论:雌激素能明显促进牙周膜成纤维细胞的迁移,促进其分化。
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     A study on the effects of different stress on cytoskeleton of human periodontal fibroblasts in vitro
     不同应力对人牙周膜成纤维细胞细胞骨架影响的体外研究
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     Soft laser such as He-Ne laser can be used eliminating inflammation,accelerating the wound healing, advancing the proliferation of periodontal fibroblasts.
     弱激光如He -Ne激光可消除炎症、促进创口愈合、促进牙周膜成纤维细胞增殖以期提高牙周新附着的形成等。
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     Conclusion: It is concluded that bFGF could accelerate periodontal fibroblasts’ migration and bFGF could inhibit the ALPase activity of osteoblast .
     结论:bFGF能明显促进牙周膜成纤维细胞的移行; bFGF能抑制成骨细胞的碱性磷酸酶活性。
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     Objective: To investigate the expression of TLR_4 in human periodontal ligament fibroblasts and the effect of lipopolysaccharide of porphyromonas gingivalis(Pg.LPS) on the expression of TLR_4.Methods: Periodontal fibroblasts come from healthy human premolars extracted due to orthodontic treatment.
     目的:探讨TLR4在体外培养的人牙周膜成纤维细胞中的表达情况。
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  “periodontal fibroblasts”译为未确定词的双语例句
     Results Fibromodulin was strongly expressed in the suprabasal gingival epithelium, periodontal ligament, alveolar bone, gingival and periodontal fibroblasts as well as their matrices.
     结果 纤维调节素在靠近口腔牙龈面的区域和牙周韧带 牙槽骨、牙周韧带 牙骨质界面有强阳性表现 ;
短句来源
     Conclusion 2 weeks after periodontal surgery is active phase of proliferation of periodontal fibroblasts. bFGF enhances fibroblast proliferation in early periodontal wound healing, and in turn accelerate periodontal regeneration.
     结论 牙周术后 2周是牙周功能细胞增殖的活跃期 ,bFGF的局部应用可明显促进牙周愈合早期牙周功能细胞的增殖 ,从而促进牙周再生
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  相似匹配句对
     The culture of human periodontal ligament fibroblasts
     人牙周膜成纤维细胞的体外培养
短句来源
     Study of Primary Cultured Human Periodontal Ligament Fibroblasts
     原代人牙周膜成纤维细胞的培养及培养方法的改进
短句来源
     Periodontal disease and atherosclerosis
     牙周炎与动脉粥样硬化
短句来源
     Laser and periodontal therapy
     激光与牙周治疗
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     Osteogenesis ability of fibroblasts
     成纤维细胞的成骨能力
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  periodontal fibroblasts
Variability of inflammatory mediator production by human periodontal fibroblasts stimulated with bacterial lipopolysaccharide
      
Cytotoxic effects, however, were induced by the polylactic acid barrier which slightly inhibited cell metabolism of the periodontal fibroblasts (XTT: 90.1%±3.6 of control value).
      
Moreover, CB-LI was observed in the periodontal fibroblasts in the alveolar half of the apical region.
      
We examined death in cultured periodontal fibroblasts, connective tissue cells that are exposed to heavy applied forces in vivo.
      
We provide below a very brief and narrow set of examples of regulation in sub populations of periodontal fibroblasts.
      
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Objective To study the distribution and expression of fibromodulin in normal periodontium, so as to understand its role in periodontal tissue homeostasis. Methods Five normal male Lewis rats were killed and their bilateral mandibular first molars with surrounding alveolar bones and gingival tissues were taken out. Human gingival fibroblasts, fibroblasts of periodontal ligament, and osteoblasts were cultured. Immunboihistochemistry with anti-fibromodulin, anti-decorin, anti-biglycan, anti-type I collagen, and...

Objective To study the distribution and expression of fibromodulin in normal periodontium, so as to understand its role in periodontal tissue homeostasis. Methods Five normal male Lewis rats were killed and their bilateral mandibular first molars with surrounding alveolar bones and gingival tissues were taken out. Human gingival fibroblasts, fibroblasts of periodontal ligament, and osteoblasts were cultured. Immunboihistochemistry with anti-fibromodulin, anti-decorin, anti-biglycan, anti-type I collagen, and anti-type Ⅲ collagen antibodies and RT-PCR were used to detect the tissue distribution and cellular localization of fibromodulin and related proteoglycans, decorin and biglycan, and type Ⅰ and type Ⅲ collagens. Results Fibromodulin was strongly expressed in the suprabasal gingival epithelium, periodontal ligament, alveolar bone, gingival and periodontal fibroblasts as well as their matrices. Strong expression was noted in the area close to oral gingival aspect and the interfaces of periodontal ligament-alveolar bone and periodontal-ligament-cementum. Decorin was strongly expressed in the area close to the gingival sulcus in gingival tissue. Biglycan was stained evidently in gingival epithelium. Fibromodulin, decorin and biglycan mRNAs were strongly expressed in osteoblasts. mRNAs of type Ⅰ and type Ⅲ collagens were strongly expressed in gingival fibroblasts. Conclusion Fibromodulin may interact with other small proteoglycans to regulate the network formation of periodontal collagen fibers, and may be involved in mineralization of the alveolar bone and cementum.

目的 研究纤维调节素 (fibromodulin)在正常牙周组织中的分布和表现 ,以明确纤维调节素在牙周组织自身稳定中的作用。方法 用免疫组织化学和逆转录 -聚合酶链反应技术 ,对正常Lewis鼠磨牙牙周组织的纤维调节素及相关蛋白多糖和胶原的组织分布和牙周细胞的mRNA表现进行分析。结果 纤维调节素在靠近口腔牙龈面的区域和牙周韧带 牙槽骨、牙周韧带 牙骨质界面有强阳性表现 ;核心蛋白聚糖强阳性表现于牙龈组织龈沟附近的区域 ;双糖链蛋白聚糖则在牙龈上皮着色明显。从mRNA的表现可以看出 ,纤维调节素 ,核心蛋白聚糖和双糖链蛋白聚糖在成骨细胞中强烈表现 ,其蛋白密度是其他两种细胞的 1~ 3倍 ;Ⅰ型、Ⅲ型胶原的mRNA在牙龈成纤维细胞中表现水平较高 ,其蛋白密度是其他两种细胞的 1 5倍以上。结论 纤维调节素可能与其他小蛋白多糖相互作用 ,调节胶原纤维的网络形成 ,并可能参与牙槽骨和牙骨质矿化

AIM:To study the effects of different stress on microfilaments of human periodontal fibroblasts cultured in vitro.METHODS:Cyclic strain force, fluid shear stress and compressive pressure force were applied on the third fifth passage human periodontal ligament cells respectively. Morphological changes of cells and filaments were observed in different intervals using phase contrast microscope and Coomassie BB staining.RESULTS:The rearrangement of filaments and cell shrinkage occurred at 6 h after...

AIM:To study the effects of different stress on microfilaments of human periodontal fibroblasts cultured in vitro.METHODS:Cyclic strain force, fluid shear stress and compressive pressure force were applied on the third fifth passage human periodontal ligament cells respectively. Morphological changes of cells and filaments were observed in different intervals using phase contrast microscope and Coomassie BB staining.RESULTS:The rearrangement of filaments and cell shrinkage occurred at 6 h after cyclic fluid shear stress, and some cells died and fell off after 12 h. Whereas there were no markedly changes after12 h compressive pressure (>100 kPa) except slight cell contract and increased space between cells.

目的:研究不同应力对体外培养的人牙周膜成纤维细胞微丝形态的影响。方法:分别给第3~5代的人牙周膜成纤维细胞施加静压力、周期性牵张力和流体剪切力,用相差显微镜和考马斯亮蓝染色方法观察加力后不同时间细胞及其微丝形态的变化特征。结果:流体剪切力作用6h后,部分人牙周膜成纤维细胞出现收缩、微丝排列等方面的变化;12h后,部分细胞死亡、脱落。较大的静压力(>100kPa)作用12h后,可引起细胞间隙增大等变化,细胞骨架改变较少。结论:一定性质和力量的外力可引起体外培养的人牙周膜成纤维细胞微丝的重排、细胞贴壁及细胞形态的变化。静压力与剪切力、动态张力相比,对体外培养的人牙周膜成纤维细胞微丝形态影响较轻。

Objective To evaluate the effects of basic fibroblast growth factor(bFGF) on proliferation of periodontal fibroblast-like cells in vivo.Methods A U-shaped osseous defect was produced on the buccal side of the mesial root. Four posterior teeth were conducted in four quadrants. Each quadrant included 4 groups: control, bFGF, expanded polytetrafluoroethylene(ePTFE) membrane, bFGF+ePTFE. Each time the 4 teeth sites in one quadrant were operated weekly and each dog experienced 4 times of operations. Bromodeoxyuridine(BrdU)...

Objective To evaluate the effects of basic fibroblast growth factor(bFGF) on proliferation of periodontal fibroblast-like cells in vivo.Methods A U-shaped osseous defect was produced on the buccal side of the mesial root. Four posterior teeth were conducted in four quadrants. Each quadrant included 4 groups: control, bFGF, expanded polytetrafluoroethylene(ePTFE) membrane, bFGF+ePTFE. Each time the 4 teeth sites in one quadrant were operated weekly and each dog experienced 4 times of operations. Bromodeoxyuridine(BrdU) was injected 1 hour prior to sacrificing the dogs at 4 weeks after first surgery. Immunohistochemical method was applied to count the BrdU-labeled fibroblast-like cells.Results The number of BrdU-labeled cells reached the maximum at the 2nd week among all groups and then, decreased with time. Both bFGF and bFGF+ePTFE treated group had significantly more BrdU++ cells than remained control or ePTFE groups (P<0 05) at 1st, 2nd weeks after surgery.Conclusion 2 weeks after periodontal surgery is active phase of proliferation of periodontal fibroblasts. bFGF enhances fibroblast proliferation in early periodontal wound healing, and in turn accelerate periodontal regeneration.

目的 观察碱性成纤维细胞生长因子 (bFGF)对犬牙周成纤维细胞样细胞增殖的影响。方法 选用 4只成年杂种犬 ,将其上颌两侧的前磨牙 (P1_3)、第一磨牙 (M1 )、下颌两侧的前磨牙 (P2_4 )、第一磨牙 (M1 )作为实验牙。在每个象限 4个实验牙的近中根颊侧人工制备“U”形骨缺损 ,并设计为 4组 ,即对照组、bFGF组、ePTFE组、bFGF +ePTFE组。每周手术 1次 ,每次手术做 1个象限的 4个牙位 ,连续 4次。完成 4次手术后 1周处死动物。动物处死前 1h注射尿嘧啶脱氧核苷 (BrdU) ,标本行免疫组化染色 ,显微镜下计数BrdU标记的成纤维细胞样细胞。结果 各组中BrdU+ 细胞数均于术后 2周最多 ,术后 3、4周显著减少。术后 1、2周 ,bFGF组和bFGF +ePTFE组的BrdU+ 细胞明显多于对照组和ePTFE组。结论 牙周术后 2周是牙周功能细胞增殖的活跃期 ,bFGF的局部应用可明显促进牙周愈合早期牙周功能细胞的增殖 ,从而促进牙周再生

 
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