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bone marrow biopsy specimens
相关语句
  骨髓活检标本
     Detection of B-CelI CIonality in Paraffin-Embedded Bone Marrow Biopsy Specimens by Polymerase Chain Reaction
     应用PCR检测石蜡包埋骨髓活检标本B淋巴细胞克隆性增生
短句来源
  骨髓活检组织
     Bone marrow biopsy specimens from 95 adult patients with acute leukemia (70 cases with newly diagnosed untreated acute leukemia, 5 cases with relapse/refractory acute leukemia, 20 cases with acute leukemia achieving bone marrow remission) and 15 normal controls were referred to our experiments.
     国内外尚未见报道。 我们以95例急性白血病患者(包括初发未治70例,复发难治5例和骨髓缓解 20例)和 15名正常成人骨髓活检组织标本为研究对象。
短句来源
     Methods Sixty-two formalin fixed, paraffin embedded bone marrow biopsy specimens were studied. Immunohistochemical and immunoglobulin heavy chain ( IgH ) and T-cell receptor gene rearrangement studies were performed in each case.
     材料与方法 对62例甲醛固定、石蜡包埋的骨髓活检组织,分别做了组织学、EnVision法观察和免疫球蛋白重链(IgH)基因和TCRγ基因重排检测。
短句来源
     Methods One hundred and eighty eight formalin fixed and paraffin embedded bone marrow biopsy specimens were studied.
     方法对188例淋巴瘤患者甲醛固定、石蜡包埋的骨髓活检组织进行临床病理及组织学观察, 并行免疫组织化学染色。
短句来源
  “bone marrow biopsy specimens”译为未确定词的双语例句
     68 cases(98.6%)and 24 cases (34.8%) developed anemia and pancytopenia respectively at diagnosis. Bone marrow aspirate smears showed erythrocyte dysplasia in 91.2% of these patients and granulocytic dysplasia in 34.8% of these patients ,respectively. Bone marrow biopsy specimens showed ALIP (abnormal locatization of immature precursors) in 45.4%(15/33) of patients .
     68例(98.6%)和24例(34.8%)分别有贫血和全血细胞减少,骨髓红系有病态造血达91.2%,粒系病态造血为79.4%,骨髓活检发现不成熟前体细胞异常定位(ALIP)者为45.4%。
短句来源
     Bone marrow aspirate smears showed megaloblastoid erthropoiesis and granulocytopoiesis in 27.3% and 24% patients, micromegakaryocytes were 30.7%. Bone marrow biopsy specimens showed the islands of erythroblasts and abnormal localization of immature precursors(ALIP) in 33.3% and 52.8% patients.
     骨髓中红、粒巨幼样变分别占 2 7.3 %和 2 4%,小巨核细胞检出率占 3 0 .7%,骨髓活检示幼红细胞岛和未成熟前体粒细胞位置异常 (ALIP)现象分别占 3 3 .3 %和 5 2 .8%。
短句来源
  相似匹配句对
     Morphology of the pathogenic fungus in smear and biopsy specimens of bone marrow was observed.
     (2 )骨髓涂片及活检观察真菌形态 ;
短句来源
     Histopathological Diagnosis of Leukemias by Bone Marrow Biopsy
     白血病骨髓穿刺活检的病理诊断(附128例病理分析)
短句来源
     Detection of B-CelI CIonality in Paraffin-Embedded Bone Marrow Biopsy Specimens by Polymerase Chain Reaction
     应用PCR检测石蜡包埋骨髓活检标本B淋巴细胞克隆性增生
短句来源
     Bone Marrow Necrosis
     骨髓坏死
短句来源
     Bone marrow was normal.
     骨髓造血细胞无明显异常。
短句来源
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  bone marrow biopsy specimens
In bone marrow biopsy specimens, Sternberg-Reed cells are found in 80% of cases and fibrosis is common, though it always disappears if remission is achieved.
      
In only 7 of these 33 scans did bone marrow biopsy specimens from the iliac MDP crest contain neuroblastoma cells.
      
Signs of active infection were low-grade fever, pancytopenia, persistent splenomegaly, positive cultures for leishmania in liver and bone marrow biopsy specimens, and newly positive leishmania serology.
      
In addition, no significant correlation was observed between the Bcl-xl expression and the MVD, but MVD was significantly increased as compared to normal bone marrow biopsy specimens (p=0.02).
      
We analyzed bone marrow biopsy specimens obtained from 59 patients with newly diagnosed multiple myeloma.
      
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Among plasma cell disorders, solitary plasmacytoma (solitany-plasmacytoma of bone, SPB and extramedullary plasmacytoma, EMP) is rare as compared with mulitiple myeloma (MM). Furthermore.the relationship between solitary plasmacytoma and MM remains unclear.Between 1960 and 1994, 24 patients with SPB and 20 with EMP were treated. The criteria for diagonosis were: (1) No evidence of other lesions based on clinical and radiologic examinations;(2) Biopsy evidence of a plasma cell neoplasm; (3) Bone...

Among plasma cell disorders, solitary plasmacytoma (solitany-plasmacytoma of bone, SPB and extramedullary plasmacytoma, EMP) is rare as compared with mulitiple myeloma (MM). Furthermore.the relationship between solitary plasmacytoma and MM remains unclear.Between 1960 and 1994, 24 patients with SPB and 20 with EMP were treated. The criteria for diagonosis were: (1) No evidence of other lesions based on clinical and radiologic examinations;(2) Biopsy evidence of a plasma cell neoplasm; (3) Bone marrow biopsy specimen with negative findings (less than 10% plasma cell); (4) No anemia, hypercalcemia or renal involvement. The average follow-up period was 112 months (from 6 to 360 months). Fifty-four percent of patients with SPB and 40% of patients with EMP developed MM, however, there was no significant statistical difference between SPB and EMP (P <0.05).We suggested that solitary plasmacytomas be classified as two types, latent and aggressive. The former was histologically well-differentiated plasmacytomas. The latter was poorly differentiated tumors which easily progress to MM. The treatment of choice is wide excision or thorough curettage, by cryogenic necrosis with liquid nitrogen or cautery of the bony wall with phenol and the cavity filled with bone grafts or cement. All patients with apparently isolated plasmacytoma should he given if the tumor turns out to be poorly differentiated, in order to delay their progression to MM.

SOLITARYPLASMACYTOMAOFBONEANDEXTRAMEDULLARYPLASMACYTOMAYangDisheng杨迪生;FanShunwu范顺武;TaoHuimin陶惠民;HeRongxin何荣新;YeZhaoming叶招明;Zh...

Objective: To study and analyse clinically 112 cases of myelodysplastic syndromes (MDS) Methods: The general condition, clinical and laboratory features, and therapy of these patients from Oct, 1982 to Oct, 1997 were studied. Results:55 cases (49%) were less than 40 years old.111 cases (99.1%) and 95 cases (84%) developed anemia and pancytopenia respectively at diagnosis. Bone marrow aspirate smears showed megaloblastoid erythropoiesis in all patients and granulocytic dysplasia in 92% of...

Objective: To study and analyse clinically 112 cases of myelodysplastic syndromes (MDS) Methods: The general condition, clinical and laboratory features, and therapy of these patients from Oct, 1982 to Oct, 1997 were studied. Results:55 cases (49%) were less than 40 years old.111 cases (99.1%) and 95 cases (84%) developed anemia and pancytopenia respectively at diagnosis. Bone marrow aspirate smears showed megaloblastoid erythropoiesis in all patients and granulocytic dysplasia in 92% of these patients, respectively. Bone marrow biopsy specimens showed ALIP (abnormal localization of immature precursors) in 39%(14/36) of patients. The level of hemoglobin in 78% (66/85) of patients with refractory anemia (RA) and refractory anemia with ringed sideroblasts (RAS) was increased during androgen therapy, but platelet count was not. The most patients with refractory anemia with excess of blasts, refractory anemia with excess of blasts in transformation and chronic myelomonocytic leukemia died in acute leukemia. Conclusion: Bone marrow cellular morphologic dysplasia and ALIP on bone marrow biopsy are important for diagnosis of MDS. Anemia in patients with RA and RAS can be improved by androgen therapy, but how to protect against transformation from MDS to acute leukemia is going to be further studied.

目的:临床研究和分析骨髓增生异常综合征(MDS)112例。方法:总结自1982年10月至1997年10月期间MDS112例的一般情况、临床和实验室检查特点及治疗。结果:55例(49%)在40岁以下,111例(99.1%)和95例(84%)分别有贫血和全血细胞减少,全部病例骨髓红系有巨幼样变,粒系病态造血达92%,骨髓活检发现不成熟前体细胞异常定位(ALIP)者为39%(14/36),难治性贫血(RA)和难治性贫血伴环状铁粒幼细胞(RAS)型病人用雄性激素治疗后78%(66/85)血红蛋白有提高,而血小板无明显变化,原始细胞增多型难治性贫血、转化中的原始细胞增多型难治性贫血和慢性粒单细胞白血病型病人主要死于急性白血病。结论:骨髓病态造血和ALIP对诊断有重要价值,雄性激素可改善RA和RAS型病人的贫血,但如何防止MDS转化成急性白血病仍需研究

In order to perform immunohistochemistry on bone marrow biopsy specimen sections, the new method of freeze-substitution and subsequent low-temperature plastic embedding was studied. The results showed that the morphologic preservation of bone marrow tissue is excellent and all antigens of blood cells, especially labile lymphocyte surface markers were well preserved, which had an accurate localization, no diffusion, and absence of background staining. This is an ideal method...

In order to perform immunohistochemistry on bone marrow biopsy specimen sections, the new method of freeze-substitution and subsequent low-temperature plastic embedding was studied. The results showed that the morphologic preservation of bone marrow tissue is excellent and all antigens of blood cells, especially labile lymphocyte surface markers were well preserved, which had an accurate localization, no diffusion, and absence of background staining. This is an ideal method for bone marrow biopsy specimen preservation for immunohistochemistry. It is also suitable for processing of needle and endoscopic biopsy specimens.

为进行骨髓活检标本免疫组织化学检验,研究了冰冻置换低温塑料包埋技术处理骨髓活检标本的新方法。结果表明:此技术能良好地保持骨髓组织细胞形态,各种血液细胞抗原成分,尤其是敏感的淋巴细胞抗原保存良好,定位准确,没有弥散,没有背景染色。此方法适用于骨髓活检标本塑料切片的免疫组织化学检验,另外,也可用于处理其它穿刺和内镜活检标本的处理。

 
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