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急性肾衰竭
相关语句
  acute renal failure
    A Study of Pig Model of Multiple Organ Dysfunction Syndrome with Acute Renal Failure
    猪多器官功能障碍综合征合并急性肾衰竭模型的制作
短句来源
    Objective: To establish a composite pig model with multiple organ dysfunction syndrome (MODS) and acute renal failure (ARF).
    目的:建立一种多器官功能障碍综合征(MODS)合并急性肾衰竭(ARF)的动物模型。
短句来源
    Experimental study of relationship between nitric oxide and ischemic acute renal failure in rats
    一氧化氮与大鼠缺血性急性肾衰竭关系的实验研究
短句来源
    In 1964, Wu songhan reported the first case of acute renal failure after taking large dose of mutong decoctum.
    1964年,国内吴松寒最先报道了服用大剂量木通煎剂引起急性肾衰竭
短句来源
    Based on the experiment using mice suffering from acute renal failure,the middle molecular substance(MMS)content in the serum of the mice was significantly decreased by 2.5%jasmine tea,2.5%tea added with herbal medicine,or 0.3% herbal medicine,and the urea nitrogen content in the serum was remarkably decreased by 2.5% tea added with herbal medicine.
    茉莉花茶、中药和复方茶对急性肾衰竭小鼠的生化及免疫功能试验结果表明,2.5%花茶、2.5%复方茶和0.3%的中药均能明显降低急性肾衰竭小鼠血清中分子物质(MMS)含量。 2.5%复方茶能显著降低肾衰竭小鼠血清尿素氮含量,而花茶和单纯中药的作用不明显。
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  acute renal failure
Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation
      
An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) after liver transplantation has not been established previously.
      
The main complications after transplantation included pulmonary infection in two cases, acute renal failure in three cases and transplantation-related encephalopathy in one case.
      
Mitochondrial dysfunction at the early stage of cisplatin-induced acute renal failure in rats
      
The present study was undertaken to clarify the pathogenesis of cisplatin-induced acute renal failure at the early stage.
      
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Based on the experiment using mice suffering from acute renal failure,the middle molecular substance(MMS)content in the serum of the mice was significantly decreased by 2.5%jasmine tea,2.5%tea added with herbal medicine,or 0.3% herbal medicine,and the urea nitrogen content in the serum was remarkably decreased by 2.5% tea added with herbal medicine.The jasmine tea,herbal medicine or tea added with herbal medicine not only significantly promoted the hyperplasis reactions of speen lymphocytes T and B,but also...

Based on the experiment using mice suffering from acute renal failure,the middle molecular substance(MMS)content in the serum of the mice was significantly decreased by 2.5%jasmine tea,2.5%tea added with herbal medicine,or 0.3% herbal medicine,and the urea nitrogen content in the serum was remarkably decreased by 2.5% tea added with herbal medicine.The jasmine tea,herbal medicine or tea added with herbal medicine not only significantly promoted the hyperplasis reactions of speen lymphocytes T and B,but also in-creased the activities of lymphocytes IL-2 and IL-3.Mechanism of protecting kideny functions by jasmine tea and tea added with herbal medicine was discussed.

茉莉花茶、中药和复方茶对急性肾衰竭小鼠的生化及免疫功能试验结果表明,2.5%花茶、2.5%复方茶和0.3%的中药均能明显降低急性肾衰竭小鼠血清中分子物质(MMS)含量。2.5%复方茶能显著降低肾衰竭小鼠血清尿素氮含量,而花茶和单纯中药的作用不明显。花茶、中药、复方茶均可显著促进小鼠脾T、B淋巴细胞增殖反应,而且都能增强小鼠脾淋巴细胞IL-2、IL-3的活性。文中还对花茶和复方茶保护肾功能的机理进行了讨论。

Objective To study the effects of nitric oxide (NO) on acute renal failure (ARF) induced by ischemia reperfusion in rats Methods ARF model was produced by clamping both renal pedicals 45min followed by releasing clamps These rats recieved saline,L arginine (300mg/kg),D arginine (300mg/kg),N nitro L arginine (NLA,10mg/kg) respectively after releasing clamps Results After L arginine administration inulin clearance and urine flow rate increased(P<0 ...

Objective To study the effects of nitric oxide (NO) on acute renal failure (ARF) induced by ischemia reperfusion in rats Methods ARF model was produced by clamping both renal pedicals 45min followed by releasing clamps These rats recieved saline,L arginine (300mg/kg),D arginine (300mg/kg),N nitro L arginine (NLA,10mg/kg) respectively after releasing clamps Results After L arginine administration inulin clearance and urine flow rate increased(P<0 05),fractional sodium excretion decreased(P<0 05), and renal physiological damage was attenuated (P<0 05), when compared with those after saline administration Although NLA remarkably increased mean arterial pressure (P<0 01),inulin clearance significantly diminished (P<0 01) There were not statistical differences in the above parameters between D arginine group and saline group Conclusion In early stage of ARF induced by ischemia reperfusion in rats,L arginine derived NO is capable of improving suppressed renal function and attenuating renal tissue damage,whereas NO synthase inhibitor NLA exagerate kidneys injurys

目的 研究一氧化氮(NO)在缺血性急性肾衰竭病理过程中的作用。方法 通过夹闭大鼠双侧肾蒂45分钟后再松夹复制出急性肾衰(ARF)模型。各组在松夹后分别静滴生理盐水、L精氨酸、D精氨酸、N硝基L精氨酸(NLA)。结果 与盐水对照组相比,L精氨酸组菊糖清除率和再灌注早期的尿流率增高(P< 005),尿钠排泄分数下降(P< 005),肾病理损害也较轻(P< 005)。NLA虽升高血压(P< 001),但菊糖清除率反而降低(P< 001)。D精氨酸组与对照组相比无差异。结论 L精氨酸通过增加NO的生成,能减轻ARF时的肾损害

Objective: To establish a composite pig model with multiple organ dysfunction syndrome (MODS) and acute renal failure (ARF). Methods: 12 pigs were randomly divided into two groups, group E received cecal ligation and puncture (CLP) plus bilateral ureteral ligation and group C received sham operation. The animals were infused with solutions containing glucose and sodium chloride for 6 days. Results: In group E, the rectal temperature increased 4 hours after operation. The indexes enhanced 72 hours after operation,...

Objective: To establish a composite pig model with multiple organ dysfunction syndrome (MODS) and acute renal failure (ARF). Methods: 12 pigs were randomly divided into two groups, group E received cecal ligation and puncture (CLP) plus bilateral ureteral ligation and group C received sham operation. The animals were infused with solutions containing glucose and sodium chloride for 6 days. Results: In group E, the rectal temperature increased 4 hours after operation. The indexes enhanced 72 hours after operation, including SCr from (91.40 ± 10. 85) μmol/L to (995. 25 ±125. 28)μmol/L, BUN from (4. 08 ± 0. 93) mmol/L to (48. 80±1.4l)mmol/L, serum kalium from (3.81 ±0.57)mmol/ L to (7. 37±0. 66)mmol/L, ALT from (62. 40 ±8. 20)U/L to (115. 75± 33. 42)U/L, AST from (53. 00 ±14. 85)U/L to (278. 00±96. 20)U/L and PaCO2 from (37. 68±3. 10)mmHg to (51.98±4.5l) mmHg ( P < 0. 01). The blood value of pH decrease from 7. 38±0. 04 to 7. 25±0. 05, ( P < 0. 05), and the value of MAP reduced from (160. 20 ± 18. 58) mmHg to (105. 75 ±13. 96)mmHg( P <0.01). The mortality in group E is 100% within 6 days after operation, and the survival time was (74. 96 ±23. 00)h. All the animals, survived in group C. Conclusion: The dysfunction in organs and systems was caused by severe intra-abdominal infection induced by CLP, meanwhile, acute anuric renal failure was produced by bilateral ureteral ligation. It was successful to produce the pig model with MODS and ARF.

目的:建立一种多器官功能障碍综合征(MODS)合并急性肾衰竭(ARF)的动物模型。方法:12只健康杂交家猪随机分成实验组(E组)和假手术对照组(C组)。E组行盲肠结扎加穿孔(CLP),并加做双侧输尿管结扎术(UL)制作成MODS合并ARF的动物模型,C组行盲肠和双侧输尿管探查术。两组动物均予24 h静脉输液,观察6天中动物的生命体征及主要器官功能改变。结果:E组动物在CLP+UL后4 h直肠温度升高;术后72 h血清肌酐(Cr)、尿素氮(BUN)、K+、丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)水平分别从术前的(91.40±10.85))μmol/L、(4.08±0.93)mmol/L、(3.81±0.57)mmol/L、(62.40±8.20)U/L、(53.00±14.85)U/L升高至(995.25±125.28)μmol/L、(48.80±1.41)mmol/L、(7.37±0.66)mmol/L、(115.75±33.42)U/L、(278.00±96.20)U/L,动脉血二氧化碳分压(PaCO2)从术前的(37.68±3.10)mmHg(1mmHg=0.133 kPa)升高至(5...

目的:建立一种多器官功能障碍综合征(MODS)合并急性肾衰竭(ARF)的动物模型。方法:12只健康杂交家猪随机分成实验组(E组)和假手术对照组(C组)。E组行盲肠结扎加穿孔(CLP),并加做双侧输尿管结扎术(UL)制作成MODS合并ARF的动物模型,C组行盲肠和双侧输尿管探查术。两组动物均予24 h静脉输液,观察6天中动物的生命体征及主要器官功能改变。结果:E组动物在CLP+UL后4 h直肠温度升高;术后72 h血清肌酐(Cr)、尿素氮(BUN)、K+、丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)水平分别从术前的(91.40±10.85))μmol/L、(4.08±0.93)mmol/L、(3.81±0.57)mmol/L、(62.40±8.20)U/L、(53.00±14.85)U/L升高至(995.25±125.28)μmol/L、(48.80±1.41)mmol/L、(7.37±0.66)mmol/L、(115.75±33.42)U/L、(278.00±96.20)U/L,动脉血二氧化碳分压(PaCO2)从术前的(37.68±3.10)mmHg(1mmHg=0.133 kPa)升高至(51.98±4.51)mmHg(P均<0.01);pH值分别从术前的7.38±0.04下降至7.25±0.05(P<0.05);平均动脉压(MAP)从术后0 h的(160.20±18.58)mmHg降至术后72 h的(105.75±13.96)mmHg(P<0.01),6天内动物全部死亡,平均生存时间(74.96±23.00)h。C组全部存活。且上述指标基本正常。结论:盲肠结扎加穿孔造成严重腹腔感染致明显的多器官功能障?

 
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