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急性肾衰竭
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  acute renal failure
    Acute Renal Failure and Cell Cycle Regulatory Proteins cyclin E/CDK2 and p27~(kip1)
    急性肾衰竭与细胞周期调节蛋白cyclin E/CDK2和P27~(kip1)
短句来源
    Methods Twenty-three patients with acute renal failure were divided into the treatment group (n=10) and the control group (n=13) by a simple random method.
    方法采取抛硬币法将23例急性肾衰竭患者随机分为治疗组(n=10)和对照组(月=13)。
短句来源
    Objective To observe the curative effect and mechanisms of Xuebijing in the acute renal failure(ARF).
    目的观察中药血必净注射液(简称血必净)治疗急性肾衰竭(ARF)临床疗效及作用机制。
短句来源
    Diagnosis and treatment of 23 cases with rhabdomyolysis related acute renal failure
    横纹肌溶解综合征致急性肾衰竭23例诊治分析
短句来源
    Clinical Evidence Acute renal failure
    临床证据(14) 急性肾衰竭
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  “急性肾衰竭”译为未确定词的双语例句
    Methods 64 patients with ARF were randomly divided into two groups:Ⅰgroup,34 patients treated with routine treatment and intravenous drip of Xuebijing, andⅡ group, 30 patients treated with routine treatment.
    方法将64例急性肾衰竭患者随机分组,Ⅰ组在西医综合治疗基础上加用血必净静脉点滴,Ⅱ组仅采用西医综合治疗。
短句来源
    Clinical and Pathological Analysis of Senile Acute Renal Failue (Report of 40 cases)
    老年急性肾衰竭40例临床与病理分析
短句来源
    And every group was divided into 3 sub-groups,1 hour-group( 1 hour after glycerol injection ), 6 hour-group( 6 hours after glycerol injection ) and 24 hour-group( 24 hours after glycerol injection ).
    根据观察各时间组又分为三个亚组即甘油注射后1小时组、甘油注射后6小时组和24小时组。 2建立急性肾衰竭模型:各组大鼠禁水24小时,急性肾衰组大鼠给于50%甘油生理盐水10ml/kg,双后肢肌肉注射;
短句来源
    [Background] Inflammation and oxidative stress often happen after cardiac surgery because the contact of circling pipeline and oxidation instrument, ischemia reperfusion injury and surgical trauma. When this is severe, multiple organ dysfunction syndrome (MODS) arised.
    【背景】心脏手术体外循环(Cardiopulmonary bypass,CPB)时因血液与循环管道和氧合器接触、缺血再灌注损伤、手术损伤等因素常导致术后炎症反应和氧化应激,严重时可发生多脏器功能衰竭,合并重症急性肾衰竭(Acute renal failure,ARF)的多脏器功能障碍综合征(Multiple organ dysfunction syndrome,MODS)患者的死亡率很高。
短句来源
    Objective:To study the effects of CGRP on ARF and to discuss the changes and effects of CGRP and ET-1 ARF.
    目的:研究降钙素基因相关肽(CGRP)对急性肾衰竭(ARF)的影响,探讨CGRP和内皮素-1(ET-1)在ARF中的变化和作用。
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  acute renal failure
Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation
      
An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) after liver transplantation has not been established previously.
      
The main complications after transplantation included pulmonary infection in two cases, acute renal failure in three cases and transplantation-related encephalopathy in one case.
      
Mitochondrial dysfunction at the early stage of cisplatin-induced acute renal failure in rats
      
The present study was undertaken to clarify the pathogenesis of cisplatin-induced acute renal failure at the early stage.
      
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Objective To realize and classify the aristolochic acid nephropathy (AAN) according to its clinical and pathological manifestations. Methods Fifty eight cases in our Division during October 1998 to August 2001 were reviewed, and their clinical, laboratory and pathological manifestations as well as the response of therapy were analyzed. The aristolochic acid (AA) component in some Chinese traditional drugs taken by our patients was detected with thin layer chromatography (TLC) scan. Results AAN might be divided...

Objective To realize and classify the aristolochic acid nephropathy (AAN) according to its clinical and pathological manifestations. Methods Fifty eight cases in our Division during October 1998 to August 2001 were reviewed, and their clinical, laboratory and pathological manifestations as well as the response of therapy were analyzed. The aristolochic acid (AA) component in some Chinese traditional drugs taken by our patients was detected with thin layer chromatography (TLC) scan. Results AAN might be divided the following three types: (1) acute AAN ( n =4): acute tubular necrosis and acute renal failure were its pathological and clinical characters, respectively. (2)tubular dysfunctional AAN ( n =7): tubular degradation with atrophy, and renal tubular acidosis and/ or Fanconi syndrome were its main pathological and clinical manifestations, respectively. (3) chronic AAN ( n =47): renal interstitial fibrosis with few infiltrated mononuclear cells, and chronically progressive renal failure were its dominant pathological and clinical findings, respectively. Steroid therapy was tried to treat some patients with AAN, and a few patients in the first two types obtained some good effects. AA component was demonstrated by the TLC scan in the drugs taken by our patients. Conclusion Chinese traditional drugs containing AA are able to cause a special tubulointerstitial nephropathy which may be classified three types with different outcome. The definite effects of steroid on AAN still need to be proved by further studies.

目的 总结马兜铃酸肾病病人的临床及病理表现 ,进行分型 ,以提高对此病的认识。方法 对经中日友好医院治疗的 5 8例马兜铃酸肾病病人进行了肾功能、电解质、尿酸化功能检查 ,并做肾穿刺进行了光镜、免疫荧光及电镜检查。并对部分病人所服药物的马兜铃酸成分及含量进行检测 (薄层析扫描法 )。结果 根据临床 病理表现特点 ,马兜铃酸肾病可分为 3型 :(1)急性型 (4例 ) :病理呈急性肾小管坏死 ,临床出现急性肾衰竭 ;(2 )肾小管功能障碍型 (7例 ) :病理呈肾小管变性及萎缩 ,临床出现肾小管酸中毒和 /或Fanconi综合征 ;(3)慢性型 (4 7例 ) :病理呈寡细胞性肾间质纤维化 ,临床出现慢性进行性肾衰竭 ,部分病例肾损害进展迅速。用类固醇激素对本病部分病人进行治疗 ,前二型个别病例病情好转。药物分析已证实马兜铃酸存在。结论 含马兜铃酸成分的中草药确可引起肾小管 间质肾病 ,此病至少可分为 3种临床 病理类型 ,各型预后不同。类固醇激素是否对此病确具疗效尚需进一步探讨

OBJECTIVE: To explore the mechanism of in- sulin-like growth factor-I(IGF-1) in acute renal failure(ARF). METHOD: Wistar rats were divided into three groups:Pseuoop- erative group (control, n = 16); IARF group(n = 32): rats were subjected to 45 minutes of bilateral renal ischemia; IGF-1 group(n = 16 ): a subcutaneous injection of rhIGF-I (250ng· Kg-1) was given per day after releasing clamped bilateral renal artery, Creatinine clearance(Ccr), urine protein Per 24 hours, serum and urine β2-microglobulin(β2-MG),...

OBJECTIVE: To explore the mechanism of in- sulin-like growth factor-I(IGF-1) in acute renal failure(ARF). METHOD: Wistar rats were divided into three groups:Pseuoop- erative group (control, n = 16); IARF group(n = 32): rats were subjected to 45 minutes of bilateral renal ischemia; IGF-1 group(n = 16 ): a subcutaneous injection of rhIGF-I (250ng· Kg-1) was given per day after releasing clamped bilateral renal artery, Creatinine clearance(Ccr), urine protein Per 24 hours, serum and urine β2-microglobulin(β2-MG), IGF-1, thrombox- ane(TXB2), prostaglandin F1alpha (PGF1) were measured and rend histology was observed. Ccr concentration in IARF group decreased obviously, while proteinuria per 24 hoars, β2-MG, kidney weight/body weight, serum and urine levels of TXB2 were higher and serum and urine levels of PGF1α and urine IGF were lower than those in the control group. RESULTS: To compared with IARF group, Ccr concentration showed increase and a more rapid return toward hasal values, the serum and urine levels of TXB2, urine protein per 24 hours, β2-Mg reduced and serum and urine levels of PGF1α and urine IGF increased in IFG-I group. Kidneys from rats that had received IGF-I were improved in histopathological apperance. CONCLUSION: IGF-I improves renal function, hastens recovery and accelearates re- generation of damaged tubular epithelia following ischernic acute renal failure.

目的:探讨胰岛素样生长因子I(IGF-I)对急性肾功能衰竭(ARF)的治疗作用。方法:建立大鼠缺血性急性肾衰竭模型,Wistar大鼠48只随机分成三组:假手术对照组(n=16),IARF组32只夹闭双肾动脉45min建立IARF模型(n=32),其中随机分16只为IGF-I组:每日皮下注射rhIGF-I一次(250ng.kg-1)。观察内生肌酐清除率(Ccr),24h尿蛋白,β2-MG,血、尿 IGF-I,血栓素B2(TXB2),6-酮-前列腺素 F1(6-keto-PCF1α)水平及肾脏组织形态学改变。结果:缺血后IARF组Ccr显著下降,24h尿蛋白,β2-MG下降,血、尿TXB2及肾重/体重增高,6-Keto-PGF1及尿 IGF-1水平降低,与对照组相比差异显著。 IGF-I组 Ccr升高,且较快恢复到对照水平;24 h尿蛋白,β2-MG及血、尿TXB2下降,6-keto-PGF1及尿IGF-I水平增高;肾组织学观察肾小管损伤程度减轻,肾小管上皮再生恢复快。结论:IGF-I能改善 IARF肾功能,减轻肾小管损伤程度,促进肾小管上皮再生恢复。

To investigate the clinical characteristics of patients with post traumatic acute renal failure (ARF)effect of early renal replacement therapy on their propnosis, a case control study was carried out in 71 cases of post traumatic ARF and 40 cases of post operative ARF. The effect of early renal replacement therapy on prognosis was evaluated. The incidence of post traumatic ARF in traumatic patients was 1 06%, and 16 21% in ARF. Rhabomyolysis and hypovolemia were the most common causes of ARF. Respiratory...

To investigate the clinical characteristics of patients with post traumatic acute renal failure (ARF)effect of early renal replacement therapy on their propnosis, a case control study was carried out in 71 cases of post traumatic ARF and 40 cases of post operative ARF. The effect of early renal replacement therapy on prognosis was evaluated. The incidence of post traumatic ARF in traumatic patients was 1 06%, and 16 21% in ARF. Rhabomyolysis and hypovolemia were the most common causes of ARF. Respiratory failure and coma were the predisposing factors of ARF. The incidence of multiple organ failure was 85 9% and the mortality was 70 4%. Early renal replacement therapy might improve the prognosis. The mortality of patients with Post traumatic ARF remains high, renal replacement therapy should be given as early as possible.

为探讨创伤后急性肾衰竭 (ARF)病人的临床特点及早期肾替代治疗对预后的影响 ,回顾性分析 71例创伤后ARF的临床特点、早晚期肾替代治疗效果 ,并与同期外科术后ARF病人进行了对比。结果发现 ,创伤后ARF占同期因创伤住院病人的 1 0 6 % ,占同期ARF病人数的 16 2 1% ;ARF多见于伤后发生低血容量及横纹肌溶解症的病人 ,并发呼吸和神经系统功能衰竭时 ,更易发生ARF ;其多脏器衰竭发生率为 85 9% ,病死率高达 70 4 % ;早期进行肾替代治疗可改善预后 ,其病死率 (33 3% )明显低于晚期进行肾替代治疗者(5 9 2 % )。说明创伤后ARF病人病情较重 ,预后差 ,肾替代治疗应早期进行。

 
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