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newborns with infection
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  新生儿感染
     Methods Of 48 newborns with infection,23 suffered from bacterial infection and 25 viral infection.
     方法48例新生儿感染住院患儿分2组:细菌感染组23例,病毒感染组25例。
短句来源
     Detectation of urinary high molecular alkaline phosphatase in newborns with infection and its significance
     新生儿感染尿大分子碱性磷酸酶的检测及意义
短句来源
     Change of pathogens isolated from newborns with infection
     新生儿感染病原菌变迁
短句来源
     The change and clinical significance of the molecule CD in the newborns with infection.
     新生儿感染时CD分子变化及临床意义
短句来源
     Objective To investigate the changes of urinary high molecular alkaline phosphatase (HMAP) in newborns with infection and to offer early and sensitive diagnostic methods for renal dysfunction.
     目的 研究新生儿感染患儿尿大分子碱性磷酸酶 (HMAP)的变化 ,为肾功能损害提供早期敏感的诊断方法。
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  “newborns with infection”译为未确定词的双语例句
     The 21 jaundiced newborns with infection were divided into the severe hyperbilirubinemia group (serum bilirubin≥205.2 μmol/L, n=10) and the mild hyperbilirubinemia group (serum bilirubin <205.2 μmol/L, n=11). There was no significant difference of TFPI level between the severe hyperbilirubinemia group and mild hyperbilirubinemia group (P>0.05).
     根据患儿血清胆红素 (SB)浓度 ,将 2 1例感染性黄疸新生儿分为胆红素重度增高感染组 (SB≥ 2 0 5 2 μmol/L ,n =10 )和胆红素轻度增高感染组 (SB <2 0 5 2 μmol/L ,n =11) ,两组间TFPI水平差异无显著性 (P >0 0 5 )。
短句来源
     The aim of this study was to observe the changes of TF and TFPI in plasma of newborns with infection jaundice and to research the effect of jaundice and infection on the balance of TF and TFPI in newborns. Methods The content of TF and TFPI in plasma of 21 jaundiced newborns with infection and 8 jaundiced newborns without infection as control was determined quantitatively with the enzyme-linked immunosorbent assay (ELISA).
     方法 运用酶联免疫吸附法 (ELISA)测定 8例非感染性高胆红素血症新生儿 (对照组 )及 2 1例感染性黄疸新生儿 (感染组 )血浆TF和TFPI水平。
短句来源
     Conclusions Renal injury is common in newborns with infection. Urinary HAMP and β 2 -MG are sensitive diagnostic parameters,which may be used for early detection of the renal injury in newborns with infection.
     结论 感染新生儿常存在肾功能损害 ,尿HMAP可作为监测感染新生儿肾损害的早期诊断指标
短句来源
     Objective To analyze the clinical manifestation of newborns with infection caused by staphylococcus aureus (S. aureus) and investigate the antibiotic-resistance phenotype of these strains.
     目的了解新生儿金黄色葡萄球菌(金葡菌)感染的临床特点及其菌株表型。
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  相似匹配句对
     Hydronephrosis in newborns
     新生儿肾积水
短句来源
     THE EXPERIENCE OF CHEILOPLASTY IN NEWBORNS
     新生儿唇裂修复术探讨
短句来源
     Studies on the Rotavirus Infection in Newborns
     新生儿轮状病毒感染的探讨(附89例分析)
短句来源
     THE NEWBORNS WITH VENTILATOR-ASSOCIATED PNEUMONIA
     新生儿通气相关性肺炎
短句来源
     Change of pathogens isolated from newborns with infection
     新生儿感染病原菌变迁
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Objective Tissue factor (TF) is an important factor in extrinsic coagulation. Tissue factor pathway inhibitor (TFPI) is a negative regulator of coagulation mediated by TF. Studies on TF and TFPI focus mainly on adult objects, seldom have been done on newborns, especially on sick newborns. The aim of this study was to observe the changes of TF and TFPI in plasma of newborns with infection jaundice and to research the effect of jaundice and infection on the balance of TF and TFPI in newborns....

Objective Tissue factor (TF) is an important factor in extrinsic coagulation. Tissue factor pathway inhibitor (TFPI) is a negative regulator of coagulation mediated by TF. Studies on TF and TFPI focus mainly on adult objects, seldom have been done on newborns, especially on sick newborns. The aim of this study was to observe the changes of TF and TFPI in plasma of newborns with infection jaundice and to research the effect of jaundice and infection on the balance of TF and TFPI in newborns. Methods The content of TF and TFPI in plasma of 21 jaundiced newborns with infection and 8 jaundiced newborns without infection as control was determined quantitatively with the enzyme-linked immunosorbent assay (ELISA). Results The content of TFPI and TF in plasma of jaundiced newborn with infection was significantly higher than that of controls [TFPI (21.0±4.3)vs.(16.2±1.9) μg/L, P<0.01; TF(177±79)vs.(51±24) ng/L, P<0.01]. The ratio of TFPI/TF was significantly lower in newborn with infection jaundice than the controls (137±61 vs. 319±67, P<0.01). The 21 jaundiced newborns with infection were divided into the severe hyperbilirubinemia group (serum bilirubin≥205.2 μmol/L, n=10) and the mild hyperbilirubinemia group (serum bilirubin <205.2 μmol/L, n=11). There was no significant difference of TFPI level between the severe hyperbilirubinemia group and mild hyperbilirubinemia group (P>0.05). The TF content in the severe hyperbilirubinemia group was higher than that in the mild hyperbilirubinemia group ( 216±79 vs.141±63, P<0.01),while the ration of TFPI/TF was lower in the severe hyperbilirubinemia group than in the mild hyperbilirubinemia group (100±30 vs. 171±74, P<0.01). Conclusion Infection might induce imbalance between the coagulation inhibition and activation in newborns. Hyperbilirubinemia can aggravate the imbalance induced by the infection through increasing plasma TF level.

目的 探讨新生儿感染性黄疸患儿血浆组织因子 (TF)和组织因子途径抑制物 (TFPI)含量的变化及其意义。方法 运用酶联免疫吸附法 (ELISA)测定 8例非感染性高胆红素血症新生儿 (对照组 )及 2 1例感染性黄疸新生儿 (感染组 )血浆TF和TFPI水平。结果 感染组的血浆TFPI含量和TF含量显著高于对照组 [TFPI( 2 1 0± 4 3 )、( 16 2± 1 9) μg/L ,P <0 0 1;TF ( 177± 79)、( 5 1± 2 4)ng/L ,P <0 0 1];TFPI/TF比值显著低于对照组 ( 13 7± 61、3 19± 67,P <0 0 1)。根据患儿血清胆红素 (SB)浓度 ,将 2 1例感染性黄疸新生儿分为胆红素重度增高感染组 (SB≥ 2 0 5 2 μmol/L ,n =10 )和胆红素轻度增高感染组 (SB <2 0 5 2 μmol/L ,n =11) ,两组间TFPI水平差异无显著性 (P >0 0 5 )。胆红素重度增高感染组TF水平高于胆红素轻度增高感染组 [( 2 16± 79)、( 141± 63 )ng/L ,P <0 0 1],而...

目的 探讨新生儿感染性黄疸患儿血浆组织因子 (TF)和组织因子途径抑制物 (TFPI)含量的变化及其意义。方法 运用酶联免疫吸附法 (ELISA)测定 8例非感染性高胆红素血症新生儿 (对照组 )及 2 1例感染性黄疸新生儿 (感染组 )血浆TF和TFPI水平。结果 感染组的血浆TFPI含量和TF含量显著高于对照组 [TFPI( 2 1 0± 4 3 )、( 16 2± 1 9) μg/L ,P <0 0 1;TF ( 177± 79)、( 5 1± 2 4)ng/L ,P <0 0 1];TFPI/TF比值显著低于对照组 ( 13 7± 61、3 19± 67,P <0 0 1)。根据患儿血清胆红素 (SB)浓度 ,将 2 1例感染性黄疸新生儿分为胆红素重度增高感染组 (SB≥ 2 0 5 2 μmol/L ,n =10 )和胆红素轻度增高感染组 (SB <2 0 5 2 μmol/L ,n =11) ,两组间TFPI水平差异无显著性 (P >0 0 5 )。胆红素重度增高感染组TF水平高于胆红素轻度增高感染组 [( 2 16± 79)、( 141± 63 )ng/L ,P <0 0 1],而TFPI/TF低于胆红素轻度增高感染组 ( 10 0± 3 0、171± 74,P <0 0 1)。结论 感染可引起新生儿体内抗凝与促凝作用的平衡失调。黄疸可提高血浆TF水平 ,加重感染新生儿体内抗凝与促凝作用的失衡

Objective To investigate the changes of urinary high molecular alkaline phosphatase (HMAP) in newborns with infection and to offer early and sensitive diagnostic methods for renal dysfunction.Methods By using monoclonal antibody,ELISA was adopted to detect the changes of urinary HMAP before and after treatment in infection group (51 cases) and the levels of urinary HMAP in normal control group (21 cases).The levels of urinary β 2 -MG and serum BUN and Cr in two groups were also detected.Results...

Objective To investigate the changes of urinary high molecular alkaline phosphatase (HMAP) in newborns with infection and to offer early and sensitive diagnostic methods for renal dysfunction.Methods By using monoclonal antibody,ELISA was adopted to detect the changes of urinary HMAP before and after treatment in infection group (51 cases) and the levels of urinary HMAP in normal control group (21 cases).The levels of urinary β 2 -MG and serum BUN and Cr in two groups were also detected.Results The levels of urinary HMAP and β 2 -MG in infection group before treatment were significantly higher than those after treatment(P<0 001) and that in control group (P<0 001). Urinary HAMP in infection group was positively correlated with β 2 -MG(P<0 001).The abnormality rates of urinary HAMP and β 2 -MG in infection group (58.82% and 74.51%) were higher than those of serum BUN and Cr (23 53% and 33 33%)(P<0 01).Conclusions Renal injury is common in newborns with infection.Urinary HAMP and β 2 -MG are sensitive diagnostic parameters,which may be used for early detection of the renal injury in newborns with infection.

目的 研究新生儿感染患儿尿大分子碱性磷酸酶 (HMAP)的变化 ,为肾功能损害提供早期敏感的诊断方法。方法 利用抗HMAP的单克隆抗体 ,ELISA方法检测尿HMAP在感染组 (5 1例 )治疗前后的变化及在对照组 (3 6例 )的水平 ,并测定两组的尿 β2 微球蛋白 (β2 MG)和血清尿素氮 (BUN)、肌酐 (Cr)水平。结果 感染组治疗前尿HMAP、β2 MG水平显著高于治疗后和对照组 (P =0 0 0 0 1) ,感染组尿HMAP、β2 MG呈直线正相关(P <0 0 0 1) ,二者的异常发生率 (5 8 82 %和 74 5 1% )高于血清BUN、Cr(2 3 5 3 %和 3 3 3 3 % ) (P <0 0 1)。结论 感染新生儿常存在肾功能损害 ,尿HMAP可作为监测感染新生儿肾损害的早期诊断指标

Objective To assess the clinical characteristic and risk factors of hospital acquired pneumonia in newborns caused by extended-spectrum 3-lactamase (ESBLs )-producing strains. Methods Clinical feature, pathogens, and therapeutic results of the 81 newborns with hospital acquired pneumonia were reviewed. Results Thirty-four ESBL-produing strains were isolated from the respiratory tract specimens of 31 cases, 50 of non-ESBL-producing strains were identified in the other 50 cases. There were high resistance to the...

Objective To assess the clinical characteristic and risk factors of hospital acquired pneumonia in newborns caused by extended-spectrum 3-lactamase (ESBLs )-producing strains. Methods Clinical feature, pathogens, and therapeutic results of the 81 newborns with hospital acquired pneumonia were reviewed. Results Thirty-four ESBL-produing strains were isolated from the respiratory tract specimens of 31 cases, 50 of non-ESBL-producing strains were identified in the other 50 cases. There were high resistance to the third-generation cephalosporins, aztreonam, ampicillin for ESBL-producing strains, but these strains were all sensitive to imipenem, and partially sensitive to amikacin and cefepime. The isolation rate of ESBL-producing strains in patients treated by the third-generation cephalosporins and other antimicrobial agents was 65.12% and 7.89% respectively ( P <0.01). Isolation rate of ESBL-producing strains in premature newborns was 63.64%, which was significantly higher than that of full-term newborns (20.83% ) ( P < 0.01). Average mechanical ventilation time in the newborns with infection caused by non-ESBL-producing strains (5.6 d + 1.7 d) was significantly lower than that by ESBL-producing strains (9.8 d + 2.9 d) ( P < 0.01). Conclusion Extensive or long time use of the third-generation cephalosporins, premature newborns, and long time mechanical ventilation were the risk factors of the infection caused by ESBL-producing strains. Imipenem/cilastatin was the most effective antimicrobial agents for ESBL-producing strain infection.

目的探讨新生儿病房超广谱β-内酰胺酶菌株所致院内肺炎的临床特点及相关因素。方法总结我 院新生儿科产超广谱β-内酰胺酶(ESBLs)细菌所致院内肺炎患儿的临床表现、病原学情况、影响因素及治疗转归。 结果在81例院内肺炎的新生儿呼吸道分泌物中培养出产ESBLs细菌34株,来源于31例新生儿院内肺炎的患 儿,主要以肺炎克雷伯菌、大肠埃希菌为主;同期同类菌属中非产ESBLs菌株所致的新生儿院内肺炎50例,致病菌 株50株。产ESBLs菌株对三代头孢菌素、氨曲南、氨苄西林耐药率高,对亚胺培南普遍敏感,对阿米卡星、头孢吡 肟部分敏感。使用三代头孢菌素治疗组与其它抗菌药物治疗组产ESBLs菌株分离率分别为65.12%,7.89%,两组 比较,差异有显著性(P<0.01);早产儿组产ESBLs细菌菌株分离率(63.64%)明显高于足月儿组(20.83%),两 组比较,差异有显著性(P<0.01);在本组研究的患儿疾病种类中,以新生儿感染性肺炎、新生儿肺透明膜病患儿 院内感染产ESBLs细菌的分离率较高,分别为70.00%,58.33%;非产ESBLs细菌感染组平均机械通气时间为5.6 ±1.7 d,明显低于产ESBLs细菌感...

目的探讨新生儿病房超广谱β-内酰胺酶菌株所致院内肺炎的临床特点及相关因素。方法总结我 院新生儿科产超广谱β-内酰胺酶(ESBLs)细菌所致院内肺炎患儿的临床表现、病原学情况、影响因素及治疗转归。 结果在81例院内肺炎的新生儿呼吸道分泌物中培养出产ESBLs细菌34株,来源于31例新生儿院内肺炎的患 儿,主要以肺炎克雷伯菌、大肠埃希菌为主;同期同类菌属中非产ESBLs菌株所致的新生儿院内肺炎50例,致病菌 株50株。产ESBLs菌株对三代头孢菌素、氨曲南、氨苄西林耐药率高,对亚胺培南普遍敏感,对阿米卡星、头孢吡 肟部分敏感。使用三代头孢菌素治疗组与其它抗菌药物治疗组产ESBLs菌株分离率分别为65.12%,7.89%,两组 比较,差异有显著性(P<0.01);早产儿组产ESBLs细菌菌株分离率(63.64%)明显高于足月儿组(20.83%),两 组比较,差异有显著性(P<0.01);在本组研究的患儿疾病种类中,以新生儿感染性肺炎、新生儿肺透明膜病患儿 院内感染产ESBLs细菌的分离率较高,分别为70.00%,58.33%;非产ESBLs细菌感染组平均机械通气时间为5.6 ±1.7 d,明显低于产ESBLs细菌感染组(9.8±2.9 d),两组比较,差异有显著性(P<0.01)。结论广泛或长时 间使用第三头孢菌素、早产、长时间机械通气为产ESBLs细菌感染的危险因素;对于产ESBLs

 
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